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R. Katherine Hyde
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Journal Articles

PTBP1, an RNA Binding Protein and Splicing Regulator, Binds RUNX1 and Co-Localizes at Target Gene Promoters in Leukemia

Arjun Dhir, Alexander Ethell, Kevin Tur-Rodriguez, Jim Persinger, Michelle Becker, Abu Rafay, Vikas Kumar, Sandipan Brahma, Jordan Rowley, R. Katherine Hyde
Journal: Blood
Blood (2024) 144 (Supplement 1): 2728.
https://doi.org/10.1182/blood-2024-205878
Published: 2024
Journal Articles

CBFB-MYH11 Is Required for the Maintenance of Inv(16) AML

Sipra Panda, Yiqian Wang, Lisa Richter, Michelle Becker, Lisa J Garrett, Cecilia Rivas, Lemlem Alemu, Ling Zhao, Paul P. Liu, R. Katherine Hyde
Journal: Blood
Blood (2022) 140 (Supplement 1): 2995–2996.
https://doi.org/10.1182/blood-2022-169475
Published: 2022
Journal Articles

Polymeric CXCR4 Inhibitors Exhibit Novel Anti-Leukemic Effects

Calvin Lam, Ekta Kapoor, Siyuan Tang, David Oupicky, R. Katherine Hyde
Journal: Blood
Blood (2022) 140 (Supplement 1): 9080–9081.
https://doi.org/10.1182/blood-2022-169813
Published: 2022
Journal Articles

RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development

Tao Zhen, Yaqiang Cao, Gang Ren, Ling Zhao, R. Katherine Hyde, Guadalupe Lopez, Dechun Feng, Lemlem Alemu, Keji Zhao, P. Paul Liu
Journal: Blood
Blood (2020) 136 (21): 2373–2385.
https://doi.org/10.1182/blood.2020007747
Published: 2020
Includes: Supplemental data
Journal Articles

Title: Runx1 Is Indispensable for Leukemia Development Induced By Cbfb-MYH11

Tao Zhen, PhD, Erika Mijin Kwon, PhD, R. Katherine Hyde, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Lemlem Alemu, BS, Paul P Liu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1337.
https://doi.org/10.1182/blood-2018-99-116930
Published: 2018
Journal Articles

Cbfb-MYH11 + Leukemia Stem Cells Are Heterogeneous and Show Dynamic Marker Expression

Yiqian Wang, BS, Michelle Becker, Lisa Richter, R. Katherine Hyde, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2504.
https://doi.org/10.1182/blood.V130.Suppl_1.2504.2504
Published: 2017
Journal Articles

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

Tao Zhen, Erika M. Kwon, Ling Zhao, Jingmei Hsu, R. Katherine Hyde, Ying Lu, Lemlem Alemu, Nancy A. Speck, P. Paul Liu
Journal: Blood
Blood (2017) 130 (22): 2431–2442.
https://doi.org/10.1182/blood-2017-04-780106
Published: 2017
Includes: Supplemental data
Journal Articles

RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML

Yiqian Wang, Kira Hannon, Lisa Richter, Michelle Becker, Lisa Garett, Cecilia Rivas, Lemlem Alemu, Ling Zhao, MD PhD, Pu Paul Liu, MD PhD, R. Katherine Hyde, PhD
Journal: Blood
Blood (2016) 128 (22): 2715.
https://doi.org/10.1182/blood.V128.22.2715.2715
Published: 2016
Journal Articles

Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development

Tao Zhen, PhD, Erika Mijin Kwon, PhD, R. Katherine Hyde, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Lemlem Alemu, Pu Paul Liu, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2722.
https://doi.org/10.1182/blood.V128.22.2722.2722
Published: 2016
Journal Articles

HDAC1 Cooperates with CBFβ-SMMHC in Regulating Gene Expression in Inversion 16 Acute Myeloid Leukemia

Lisa Richter, Yiqian Wang, Michelle Becker, R. Katherine Hyde, PhD
Journal: Blood
Blood (2016) 128 (22): 2690.
https://doi.org/10.1182/blood.V128.22.2690.2690
Published: 2016
Journal Articles

CHD7 Deficiency Inhibits CBFB-MYH11 -Induced Leukemogenesis

Tao Zhen, PhD, Ling Zhao, MD PhD, R. Katherine Hyde, PhD, Lemlem Alemu, Pu Paul Liu, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3662.
https://doi.org/10.1182/blood.V126.23.3662.3662
Published: 2015
Journal Articles

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

Brief Report
Yasuhiko Kamikubo, R. Katherine Hyde, Ling Zhao, Lemlem Alemu, Cecilia Rivas, Lisa J. Garrett, P. Paul Liu
Journal: Blood
Blood (2013) 121 (4): 638–642.
https://doi.org/10.1182/blood-2012-06-434688
Published: 2013
Includes: Supplemental data
Journal Articles

Runx1 Is Required by the Inv(16) Fusion Gene Cbfb-MYH11 .

R. Katherine Hyde, PhD, Ling Zhao, MD/PhD, Lemlem Alemu, Pu Paul Liu, MD/PhD
Journal: Blood
Blood (2012) 120 (21): 2434.
https://doi.org/10.1182/blood.V120.21.2434.2434
Published: 2012
Journal Articles

The C-Terminal of MYH11 Is Required for Cbfb-MYH11 Activity During Embryonic Hematopoiesis and Leukemogenesis

R. Katherine Hyde, PhD, Yasuhiko Kamikubo, Ling Zhao, MD, PhD, Lemlem Alemu, Lisa Garrett, Pu Paul Liu, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2472.
https://doi.org/10.1182/blood.V118.21.2472.2472
Published: 2011
Journal Articles

Runx1 Is Required for Cbfb-MYH11 Activity During Primitive Hematopoiesis

R. Katherine Hyde, PhD, Ling Zhao, MD, PhD, Lemlem Alemu, Pu Paul Liu, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1357.
https://doi.org/10.1182/blood.V118.21.1357.1357
Published: 2011
Journal Articles

Cbfb/Runx1 repression–independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11

R. Katherine Hyde, Yasuhiko Kamikubo, Stacie Anderson, Martha Kirby, Lemlem Alemu, Ling Zhao, P. Paul Liu
Journal: Blood
Blood (2010) 115 (7): 1433–1443.
https://doi.org/10.1182/blood-2009-06-227413
Published: 2010
Includes: Supplemental data
Journal Articles

Cbfb-MYH11 Can Block Hematopoiesis and Alter Gene Expression through Mechanisms Independent of Cbfb and Runx1 Repression

R. Katherine Hyde, PhD, Yasuhiko Kamikubo, MD, PhD, Lemlem Alemu, Ling Zhao, MD, PhD, Chenwei Wang, Pu Paul Liu, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 747.
https://doi.org/10.1182/blood.V112.11.747.747
Published: 2008
Journal Articles

CBFB -Independent Activities of the Inv(16) Fusion Gene CBFB-MYH11 .

R. Katherine Hyde, PhD, Claire E. Kreycik, Pu Paul Liu, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 3376.
https://doi.org/10.1182/blood.V110.11.3376.3376
Published: 2007