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Journal Articles

CBFB-MYH11 Is Required for the Maintenance of Inv(16) AML

Sipra Panda, Yiqian Wang, Lisa Richter, Michelle Becker, Lisa J Garrett, Cecilia Rivas, Lemlem Alemu, Ling Zhao, Paul P. Liu, R. Katherine Hyde

Blood (2022) 140 (Supplement 1): 2995–2996.

https://doi.org/10.1182/blood-2022-169475

Published: 2022

Journal Articles

RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development

Tao Zhen, Yaqiang Cao, Gang Ren, Ling Zhao, R. Katherine Hyde, Guadalupe Lopez, Dechun Feng, Lemlem Alemu, Keji Zhao, P. Paul Liu

Blood (2020) 136 (21): 2373–2385.

https://doi.org/10.1182/blood.2020007747

Published: 2020

Includes: Supplemental data

Journal Articles

Title: Runx1 Is Indispensable for Leukemia Development Induced By Cbfb-MYH11

Tao Zhen, PhD, Erika Mijin Kwon, PhD, R. Katherine Hyde, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Lemlem Alemu, BS, Paul P Liu, MD PhD

Blood (2018) 132 (Supplement 1): 1337.

https://doi.org/10.1182/blood-2018-99-116930

Published: 2018

Journal Articles

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

Tao Zhen, Erika M. Kwon, Ling Zhao, Jingmei Hsu, R. Katherine Hyde, Ying Lu, Lemlem Alemu, Nancy A. Speck, P. Paul Liu

Blood (2017) 130 (22): 2431–2442.

https://doi.org/10.1182/blood-2017-04-780106

Published: 2017

Includes: Supplemental data

Journal Articles

RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML

Yiqian Wang, Kira Hannon, Lisa Richter, Michelle Becker, Lisa Garett, Cecilia Rivas, Lemlem Alemu, Ling Zhao, MD PhD, Pu Paul Liu, MD PhD, R. Katherine Hyde, PhD

Blood (2016) 128 (22): 2715.

https://doi.org/10.1182/blood.V128.22.2715.2715

Published: 2016

Journal Articles

Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development

Tao Zhen, PhD, Erika Mijin Kwon, PhD, R. Katherine Hyde, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Lemlem Alemu, Pu Paul Liu, MD PhD

Blood (2016) 128 (22): 2722.

https://doi.org/10.1182/blood.V128.22.2722.2722

Published: 2016

Journal Articles

Runx1 Deficiency and MDS-Associated U2af1 Mutation Cooperate for Leukemia Development in a New Mouse Model

Tao Zhen, PhD, Dennis Liang Fei, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Harold Varmus, MD, Pu Paul Liu, MD PhD

Blood (2016) 128 (22): 964.

https://doi.org/10.1182/blood.V128.22.964.964

Published: 2016

Journal Articles

CHD7 Deficiency Inhibits CBFB-MYH11 -Induced Leukemogenesis

Tao Zhen, PhD, Ling Zhao, MD PhD, R. Katherine Hyde, PhD, Lemlem Alemu, Pu Paul Liu, MD PhD

Blood (2015) 126 (23): 3662.

https://doi.org/10.1182/blood.V126.23.3662.3662

Published: 2015

Journal Articles

The Multimerization Domain of Cbfß-SMMHC Is Required for Leukemogenesis

Ling Zhao, MD PhD, Lemlem Alemu, Jun Cheng, Tao Zhen, PhD, Alan D. Friedman, MD, Pu Paul Liu, MD PhD

Blood (2015) 126 (23): 3666.

https://doi.org/10.1182/blood.V126.23.3666.3666

Published: 2015

Journal Articles

Functional Dissection of the C Terminus of CBFβ-SMMHC Indicates a Critical Role of the Multimerization Domain during Hematopoiesis and Leukemogenesis

Ling Zhao, MD PhD, Lemlem Alemu, Jun Cheng, Tao Zhen, PhD, Alan D. Friedman, MD, Pu Paul Liu, MD PhD

Blood (2014) 124 (21): 2218.

https://doi.org/10.1182/blood.V124.21.2218.2218

Published: 2014

Journal Articles

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

Yasuhiko Kamikubo, R. Katherine Hyde, Ling Zhao, Lemlem Alemu, Cecilia Rivas, Lisa J. Garrett, P. Paul Liu

Blood (2013) 121 (4): 638–642.

https://doi.org/10.1182/blood-2012-06-434688

Published: 2013

Includes: Supplemental data

Journal Articles

Runx1 Is Required by the Inv(16) Fusion Gene Cbfb-MYH11 .

R. Katherine Hyde, PhD, Ling Zhao, MD/PhD, Lemlem Alemu, Pu Paul Liu, MD/PhD

Blood (2012) 120 (21): 2434.

https://doi.org/10.1182/blood.V120.21.2434.2434

Published: 2012

Journal Articles

KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

Ling Zhao, Jan J. Melenhorst, Lemlem Alemu, Martha Kirby, Stacie Anderson, Maggie Kench, Shelley Hoogstraten-Miller, Lauren Brinster, Yasuhiko Kamikubo, D. Gary Gilliland, P. Paul Liu

Blood (2012) 119 (6): 1511–1521.

https://doi.org/10.1182/blood-2011-02-338210

Published: 2012

Includes: Supplemental data

Journal Articles

The C-Terminal of MYH11 Is Required for Cbfb-MYH11 Activity During Embryonic Hematopoiesis and Leukemogenesis

R. Katherine Hyde, PhD, Yasuhiko Kamikubo, Ling Zhao, MD, PhD, Lemlem Alemu, Lisa Garrett, Pu Paul Liu, MD, PhD

Blood (2011) 118 (21): 2472.

https://doi.org/10.1182/blood.V118.21.2472.2472

Published: 2011

Journal Articles

Runx1 Is Required for Cbfb-MYH11 Activity During Primitive Hematopoiesis

R. Katherine Hyde, PhD, Ling Zhao, MD, PhD, Lemlem Alemu, Pu Paul Liu, MD, PhD

Blood (2011) 118 (21): 1357.

https://doi.org/10.1182/blood.V118.21.1357.1357

Published: 2011

Journal Articles

KIT with D816 Mutations Cooperates with CBFB-MYH11 for Leukemogenesis in Mice

Ling Zhao, MD, PhD, J. Joseph Melenhorst, PhD, Lemlem Alemu, Stacie Anderson, Martha Kirby, Shelley Hoogstraten-Miller, Lauren Brinster, Maggie Kench, Yasuhiko Kamikubo, D. Gary Gilliland, MD, PhD, Pu Paul Liu, MD, PhD

Blood (2011) 118 (21): 867.

https://doi.org/10.1182/blood.V118.21.867.867

Published: 2011

Journal Articles

Cbfb/Runx1 repression–independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11

R. Katherine Hyde, Yasuhiko Kamikubo, Stacie Anderson, Martha Kirby, Lemlem Alemu, Ling Zhao, P. Paul Liu

Blood (2010) 115 (7): 1433–1443.

https://doi.org/10.1182/blood-2009-06-227413

Published: 2010

Includes: Supplemental data

Journal Articles

C-KIT with D816Y/V Mutations Cooperate with CBFB-MYH11 to Accelerate Leukemogenesis in Mice.

Ling Zhao, J. Joseph Melenhorst, Ph.D., Lemlem Alemu, Martha Kirby, Stacie M Anderson, Shelley Hoogstraten-Miller, Yasuhiko Kamikubo, MD, PhD, D. Gary Gilliland, MD, PhD, Pu Paul Liu

Blood (2009) 114 (22): 274.

https://doi.org/10.1182/blood.V114.22.274.274

Published: 2009

Journal Articles

Cbfb-MYH11 Can Block Hematopoiesis and Alter Gene Expression through Mechanisms Independent of Cbfb and Runx1 Repression

R. Katherine Hyde, PhD, Yasuhiko Kamikubo, MD, PhD, Lemlem Alemu, Ling Zhao, MD, PhD, Chenwei Wang, Pu Paul Liu, MD, PhD

Blood (2008) 112 (11): 747.

https://doi.org/10.1182/blood.V112.11.747.747

Published: 2008

Journal Articles

CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus

Ling Zhao, Jennifer L. Cannons, Stacie Anderson, Martha Kirby, Liping Xu, Lucio H. Castilla, Pamela L. Schwartzberg, Rémy Bosselut, P. Paul Liu

Blood (2006) 109 (8): 3432–3440.

https://doi.org/10.1182/blood-2006-10-051508

Published: 2006

Includes: Supplemental data

NARROW

CBFB-MYH11 Is Required for the Maintenance of Inv(16) AML

RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development

Title: Runx1 Is Indispensable for Leukemia Development Induced By Cbfb-MYH11

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML

Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development

Runx1 Deficiency and MDS-Associated U2af1 Mutation Cooperate for Leukemia Development in a New Mouse Model

CHD7 Deficiency Inhibits CBFB-MYH11 -Induced Leukemogenesis

The Multimerization Domain of Cbfß-SMMHC Is Required for Leukemogenesis

Functional Dissection of the C Terminus of CBFβ-SMMHC Indicates a Critical Role of the Multimerization Domain during Hematopoiesis and Leukemogenesis

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

Runx1 Is Required by the Inv(16) Fusion Gene Cbfb-MYH11 .

KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

The C-Terminal of MYH11 Is Required for Cbfb-MYH11 Activity During Embryonic Hematopoiesis and Leukemogenesis

Runx1 Is Required for Cbfb-MYH11 Activity During Primitive Hematopoiesis

KIT with D816 Mutations Cooperates with CBFB-MYH11 for Leukemogenesis in Mice

Cbfb/Runx1 repression–independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11

C-KIT with D816Y/V Mutations Cooperate with CBFB-MYH11 to Accelerate Leukemogenesis in Mice.

Cbfb-MYH11 Can Block Hematopoiesis and Alter Gene Expression through Mechanisms Independent of Cbfb and Runx1 Repression

CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus

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American Society of Hematology

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American Society of Hematology

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