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Journal Articles

Selective Support of CAR-T Cell Therapies By Cis-Targeted IL-2 Enhances Anti-Tumor Activity and Obviates the Need for Lymphodepletion in Non-Human Primates

Sara Sleiman, Tyler Hansen, Nathan D Mathewson, Feng Shen, Miroslaw Kozlowski, Olga Shestova, Maksim Shestov, Danuta Jarocha, Vanessa Gonzalez, Joseph A. Fraietta, Hannah Thomas, Jack Swain, Raimon Duran-Struuck, Kelly D. Moynihan, Paul Bessette, Chris Kimberlin, Meghana Sukthankar, Terrence Park, Andy Yeung, Ivana Djuretic, Saar Gill
Journal: Blood
Blood (2024) 144 (Supplement 1): 499.
https://doi.org/10.1182/blood-2024-198249
Published: 2024
Journal Articles

Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy

Maxwell E. Chappell, Laura Breda, Lucas Tricoli, Amaliris Guerra, Danuta Jarocha, Carlo Castruccio Castracani, Tyler E. Papp, Naoto Tanaka, Nolan Hamilton, Michael P. Triebwasser, Valentina Ghiaccio, Megan T. Fedorky, Kandace L. Gollomp, Veronica Bochenek, Aoife M. Roche, John K. Everett, Emma J. Cook, Frederic D. Bushman, Nattiya Teawtrakul, Stavros Glentis, Antonis Kattamis, Barbara L. Mui, Ying K. Tam, Drew Weissman, Osheiza Abdulmalik, Hamideh Parhiz, Stefano Rivella
Journal: Blood
Blood (2024) 144 (15): 1633–1645.
https://doi.org/10.1182/blood.2023023349
Published: 2024
Includes: Supplemental data
Journal Articles

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Brian Estevez, Sara Borst, Danuta Jarocha, Varun Sudunagunta, Michael Gonzalez, James Garifallou, Hakon Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy Speck, Deborah L. French, Paul Gadue, Mortimer Poncz
Journal: Blood
Blood (2021) 137 (19): 2662–2675.
https://doi.org/10.1182/blood.2020006389
Published: 2021
Includes: Supplemental data
Journal Articles

GNE variants causing autosomal recessive macrothrombocytopenia without associated muscle wasting

Clinical Trials & Observations
Shoshana Revel-Vilk, Ela Shai, Ernest Turro, Nivin Jahshan, Esti Hi-Am, Galia Spectre, Hagit Daum, Yossef Kalish, Karina Althaus, Andreas Greinacher, Chaim Kaplinsky, Shai Izraeli, Rutendo Mapeta, Sri V. V. Deevi, Danuta Jarocha, Willem H. Ouwehand, Kate Downes, Mortimer Poncz, David Varon, Michele P. Lambert
Journal: Blood
Blood (2018) 132 (17): 1851–1854.
https://doi.org/10.1182/blood-2018-04-845545
Published: 2018
Includes: Supplemental data
Journal Articles

Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake

Xiuli Sim, Danuta Jarocha, Vincent Hayes, Hayley A. Hanby, Michael S. Marks, Rodney M. Camire, Deborah L. French, Mortimer Poncz, Paul Gadue
Journal: Blood
Blood (2017) 130 (2): 192–204.
https://doi.org/10.1182/blood-2017-01-761049
Published: 2017
Includes: Supplemental data
Journal Articles

Comparative analysis of human ex vivo–generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

Yuhuan Wang, Vincent Hayes, Danuta Jarocha, Xiuli Sim, Dawn C. Harper, Rudy Fuentes, Spencer K. Sullivan, Paul Gadue, Stella T. Chou, Beverly J. Torok-Storb, Michael S. Marks, Deborah L. French, Mortimer Poncz
Journal: Blood
Blood (2015) 125 (23): 3627–3636.
https://doi.org/10.1182/blood-2014-08-593053
Published: 2015
Includes: Supplemental data
Journal Articles

Comparative Analysis of Infused “Static”, Ex Vivo-Generated Platelets Vs. Infused Megakaryocytes-Generated Platelets: A Cautionary Tale

Yuhuan Wang, PhD, Vincent Hayes, Danuta Jarocha, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2014) 124 (21): 2881.
https://doi.org/10.1182/blood.V124.21.2881.2881
Published: 2014
Journal Articles

Increased Expression of Pro-Angiogenic and Decreased Expression of Osteogenic Genes by Multipotential Stromal Cells after Stimulation with Myeloma-Derived Microvesicles.

Anna Zebzda, M.Sci., Artur Jurczyszyn, M.D., Ph.D., Danuta Jarocha, M.Sci., Aleksander B. Skotnicki, M.D., Ph.D., Marcin Majka, PhD
Journal: Blood
Blood (2007) 110 (11): 3515.
https://doi.org/10.1182/blood.V110.11.3515.3515
Published: 2007
Journal Articles

Comparison of Different Strategies of MSC Isolation Revels Advantage To Expand MSC Directly from Purified CD105 + and CD271 + Cells.

Danuta Jarocha, MSci, Ewa Lesko, MSci, Mariusz Z. Ratajczak, MD, PhD, Marcin Majka, PhD
Journal: Blood
Blood (2006) 108 (11): 2566.
https://doi.org/10.1182/blood.V108.11.2566.2566
Published: 2006
Journal Articles

Different Sensitivity of Normal and Malignant Cells to HSP90 Inhibitors.

Ewa Lesko, MSci, Anna Zebzda, MSci, Danuta Jarocha, Msci, Marcin Majka, PhD
Journal: Blood
Blood (2006) 108 (11): 4377.
https://doi.org/10.1182/blood.V108.11.4377.4377
Published: 2006
Journal Articles

Unexpected Evidence That Dimethylsulphoxide (DMSO) Upregulates Expression of CXCR4 on Hematopoietic Stem/Progenitor Cells (HSPC), Increases Their Responsiveness to an SDF-1 Gradient and Enhances Homing to Bone Marrow.

Marcin Majka, PhD, Danuta Jarocha, MSci, Marcin Wysoczynski, MSci, Duygu Sag, Ewa Zuba-Surma, PhD, Jacek Kijowski, MD, PhD, Jolanta Gozdzik, MD, PhD, Mariusz Z. Ratajczak, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 1973.
https://doi.org/10.1182/blood.V106.11.1973.1973
Published: 2005