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Federico Stella
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Journal Articles

Precision targeting of the malignant clone in B-cell malignancies using chimeric antigen receptor T cells against the clonotypic IGHV3-23 B cell receptor

Free
Jean Lemoine, Ivan Cohen, Gabrielle Croston, Audrey Bochi-Layec, David Espie, Ranjani Ramasubramanian, Patrizia Porazzi, Federico Stella, Pedram Bayat, Seul Jung, Anastasia Iatrou, Andreas Agathangelidis, Stephen Schuster, Paolo Ghia, Kostas Stamatopoulos, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 2348.
https://doi.org/10.1182/blood-2025-2348
Published: 2025
Journal Articles

Delayed neurotoxicity, enterocolitis, and BCMA-CART-associated immune-related adverse events (CirAE)  are caused by CD4+ CAR T-cells

Free
Julia Han Noll, Matthew Ho, Luca Paruzzo, Federico Stella, Pooja Devi, Sonia Ndeupen, Gregory Chen, Ivan Cohen, Angel Ramirez-Fernandez, Adam Waxman, Shivani Kapur, Fang Chen, Rong Xu, Andrew Huff, Danuta Jarocha, Vrutti Patel, Audrey Bochi-Layec, Ranjani Ramasubramanian, Shan Liu, Riemke Bouvier, Vitor Souza, Heta Patel, Ziyu Li, Alberto Carturan, Peter Michener, Caitlin Hopkins, Owen Koucky, Janna Minehart, Alex Dimitri, Neel Nabar, Zainul Hasanali, Bryan Ciccarelli, Erik Williams, Robert Bartoszek, Maya Lavorando, Suyash Mohan, Vanessa Gonzalez, Patrizia Porazzi, Vijay Bhoj, Sokratis Apostolidis, Dan Vogl, David Porter, John Scholler, Caroline Diorio, Aoife Doto, John Everett, Frederic Bushman, Katherine Nathanson, Edward Stadtmauer, Sandra Susanibar-Adaniya, Alfred Garfall, Marco Ruella, Adam Cohen, Joseph Fraietta
Journal: Blood
Blood (2025) 146 (Supplement 1): 804.
https://doi.org/10.1182/blood-2025-804
Published: 2025
Journal Articles

Precision targeting of pathogenic B cells and autoantibodies in systemic lupus erythematosus using CAR T cells against the IGHV4-34 B cell receptor

Free
Audrey Bochi-Layec, Ivan Cohen, Jean Lemoine, Scott Jenks, Pedram Bayat, Ki Hyun Kim, Huiwu Zhao, Ositadimma Ugwuanyi, Federico Stella, Guido Ghilardi, Giulia Gabrielli, Sarah McCuaig, Anastasia Iatrou, Elisavet Vlachonikola, Maria Karypidou, Eleni Bouziani, Ranjani Ramasubramanian, Andreas Agathangelidis, Luca Paruzzo, Regina Bugrovsky, Puneeth Guruprasad, Li-Ping Wang, Jaryse Harris, Yunlin Zhang, Raymone Pajarillo, Portia Kreiger, Bria Fulmer, Marcos Cases, Patrizia Porazzi, E. John Wherry, Sokratis Apostolidis, Vijay Bhoj, Stephen J. Schuster, Paolo Ghia, Kostas Stamatopoulos, Edward Behrens, Ignacio Sanz, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 4120.
https://doi.org/10.1182/blood-2025-4120
Published: 2025
Journal Articles

CCR5 blockade: A therapeutic approach to uncouple CART-BCMA expansion from CART-mediated immune toxicities.

Free
Luca Paruzzo, Matthew Ho, Julia Han Noll, Federico Stella, Ivan Cohen, Angel Ramirez-Fernandez, Adam Waxman, Shivani Kapur, Fang Chen, Andrew Huff, Danuta Jarocha, Owen Koucky, Caitlin Hopkins, Alex Dimitri, Maya Lavorando, Dan Vogl, John Scholler, Aoife Doto, John Everett, Frederic Bushman, Katherine Nathanson, Patrizia Porazzi, Edward Stadtmauer, Sandra Susanibar-Adaniya, Alfred Garfall, Adam Cohen, Joseph Fraietta, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 5945.
https://doi.org/10.1182/blood-2025-5945
Published: 2025
Journal Articles

Naive CD4+ at apheresis and disease control at infusion are associated with improved efficacy in second-line CAR T-cells

Free
Federico Stella, Michael Schneider, Luca Paruzzo, Julia Han Noll, Pooja Devi, Victor Babatunde, Elise Chong, Matthew Ho, Colin Thomas, Michael Cook, Nasheed Hossain, Jordan Carter, Ziyu Li, Melody Tan, Peter Michener, Puneeth Guruprasad, Vrutti Patel, Antonio Imparato, Alberto Carturan, Jean Lemoine, Vitor Souza, Patrizia Porazzi, Joseph Fraietta, Stefan Barta, Sunita Dwivedy Nasta, Jakub Svoboda, Stephen J. Schuster, Ivan Maillard, Daniel Landsburg, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 2755.
https://doi.org/10.1182/blood-2025-2755
Published: 2025
Journal Articles

Epigenetic reprogramming via EZH1/2 inhibition enhances T cell-mediated immunotherapies against multiple myeloma

Free
Patrizia Porazzi, Martina Pucillo, Anushka Anant Padmanabhan, Siena Nason, Zhixuan Zheng, Luca Paruzzo, Matthew Ho, Peter Michener, Federico Stella, Antonio Imparato, Sandra Susanibar-Adaniya, Alfred Garfall, Joseph Fraietta, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 2160.
https://doi.org/10.1182/blood-2025-2160
Published: 2025
Journal Articles

Large B-cell lymphoma following CD19-directed CART-cell therapy failure: Impact of CAR construct on disease features and outcomes of subsequent therapies

Free
Luca Paruzzo, Amelia Mantione, Elise Chong, Sunita Dwivedy Nasta, Daniel Landsburg, Jordan Carter, Michael Cook, Eugenio Fardella, Ashkan Bigdeli, Vrutti Patel, Antonio Imparato, Colin Thomas, Vitor Souza, Alberto Carturan, Federico Stella, Martina Pucillo, Pooja Devi, Emily Tomasulo, Stefan Barta, Stephen Schuster, Eitan Halper-Stromberg, Marco Ruella, Jakub Svoboda
Journal: Blood
Blood (2025) 146 (Supplement 1): 5501.
https://doi.org/10.1182/blood-2025-5501
Published: 2025
Journal Articles

A newly identified role for IL-5 in regulating CART-associated toxicity and efficacy

Free
Alberto Carturan, Carli Stewart, Andrew Lee, Sophia Goldberg, Luca Paruzzo, Grace DeFranco, Raymone Pajarillo, Brooke Kimball, Puneeth Guruprasad, Elizabeth Siegler, Yunlin Zhang, Ruchi Patel, Federico Stella, Melody Tan, Shan Liu, Siena Nason, Patrizia Porazzi, Stephen J. Schuster, Marco Ruella, Saad Kenderian
Journal: Blood
Blood (2025) 146 (Supplement 1): 808.
https://doi.org/10.1182/blood-2025-808
Published: 2025
Journal Articles

Chimeric antigen receptor T-cell therapy in patients with coexisting malignancy and autoimmune disease

Free
Luca Paruzzo, Riemke Bouvier, Bria Fulmer, Ivan Cohen, Elise Chong, Jakub Svoboda, Sunita Dwivedy Nasta, Daniel Landsburg, Vrutti Patel, Matthew Ho, Alberto Carturan, Federico Stella, Adam Waxman, Adam Cohen, Dan Vogl, Stefan Barta, Audrey Bochi-Layec, Patrizia Porazzi, Joseph Fraietta, Alfred Garfall, Vijay Bhoj, Edward Stadtmauer, David Porter, James Riley, Peter Merkel, Stephen Schuster, Jordan Carter, Sokratis Apostolidis, Sandra Susanibar-Adaniya, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 4543.
https://doi.org/10.1182/blood-2025-4543
Published: 2025
Journal Articles

Rebuilding immunity: Kinetics and clinical impact of immune reconstitution after CAR T-cell therapy in multiple myeloma

Free
Heta Patel, Luca Paruzzo, Oxana Megherea, Matthew Ho, Thomas Luo, Dan Vogl, Shivani Kapur, Adam Waxman, Federico Stella, Alberto Carturan, Martina Pucillo, Antonio Imparato, Edward Stadtmauer, Alfred Garfall, Adam Cohen, Marco Ruella, Sandra Susanibar-Adaniya
Journal: Blood
Blood (2025) 146 (Supplement 1): 3995.
https://doi.org/10.1182/blood-2025-3995
Published: 2025
Journal Articles

Non-Restrictive Diet Does Not Increase Infections in Patients with Neutropenia after Stem Cell Transplantation: Final Analysis of the Neutrodiet Multicenter, Randomized Trial

Free
Federico Stella, Vincenzo Marasco, Giorgia Virginia Levati, Cecilia Vismara, Anna Guidetti, Annalisa Chiappella, Giulia Perrone, Cristina Tecchio, Nicola Mordini, Martina Pennisi, Giorgia Ferrara, Giorgia Gobbi, Lucia Saracino, Cristiana Carniti, Paolo Corradini
Journal: Blood
Blood (2022) 140 (Supplement 1): 417–419.
https://doi.org/10.1182/blood-2022-158662
Published: 2022
Journal Articles

Tisagenlecleucel and Axicabtagene Ciloleucel Expansion Kinetics and CAR T Cell Attributes in the Infusion Products Are Early Predictors of Clinical Efficacy

Free
Cristiana Carniti, Chiara Monfrini, Vanessa Aragona, Martina Magni, Cristina Vella, Eugenio Fardella, Riccardo Betta, Anisa Bermema, Federico Stella, Anna Dodero, Annalisa Chiappella, Anna Guidetti, Paolo Corradini
Journal: Blood
Blood (2021) 138 (Supplement 1): 3877.
https://doi.org/10.1182/blood-2021-152309
Published: 2021