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Matthew Ho
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Journal Articles

CCR5 blockade: A therapeutic approach to uncouple CART-BCMA expansion from CART-mediated immune toxicities.

Free
Luca Paruzzo, Matthew Ho, Julia Han Noll, Federico Stella, Ivan Cohen, Angel Ramirez-Fernandez, Adam Waxman, Shivani Kapur, Fang Chen, Andrew Huff, Danuta Jarocha, Owen Koucky, Caitlin Hopkins, Alex Dimitri, Maya Lavorando, Dan Vogl, John Scholler, Aoife Doto, John Everett, Frederic Bushman, Katherine Nathanson, Patrizia Porazzi, Edward Stadtmauer, Sandra Susanibar-Adaniya, Alfred Garfall, Adam Cohen, Joseph Fraietta, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 5945.
https://doi.org/10.1182/blood-2025-5945
Published: 2025
Journal Articles

Naive CD4+ at apheresis and disease control at infusion are associated with improved efficacy in second-line CAR T-cells

Free
Federico Stella, Michael Schneider, Luca Paruzzo, Julia Han Noll, Pooja Devi, Victor Babatunde, Elise Chong, Matthew Ho, Colin Thomas, Michael Cook, Nasheed Hossain, Jordan Carter, Ziyu Li, Melody Tan, Peter Michener, Puneeth Guruprasad, Vrutti Patel, Antonio Imparato, Alberto Carturan, Jean Lemoine, Vitor Souza, Patrizia Porazzi, Joseph Fraietta, Stefan Barta, Sunita Dwivedy Nasta, Jakub Svoboda, Stephen J. Schuster, Ivan Maillard, Daniel Landsburg, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 2755.
https://doi.org/10.1182/blood-2025-2755
Published: 2025
Journal Articles

Epigenetic reprogramming via EZH1/2 inhibition enhances T cell-mediated immunotherapies against multiple myeloma

Free
Patrizia Porazzi, Martina Pucillo, Anushka Anant Padmanabhan, Siena Nason, Zhixuan Zheng, Luca Paruzzo, Matthew Ho, Peter Michener, Federico Stella, Antonio Imparato, Sandra Susanibar-Adaniya, Alfred Garfall, Joseph Fraietta, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 2160.
https://doi.org/10.1182/blood-2025-2160
Published: 2025
Journal Articles

Delayed neurotoxicity, enterocolitis, and BCMA-CART-associated immune-related adverse events (CirAE)  are caused by CD4+ CAR T-cells

Free
Julia Han Noll, Matthew Ho, Luca Paruzzo, Federico Stella, Pooja Devi, Sonia Ndeupen, Gregory Chen, Ivan Cohen, Angel Ramirez-Fernandez, Adam Waxman, Shivani Kapur, Fang Chen, Rong Xu, Andrew Huff, Danuta Jarocha, Vrutti Patel, Audrey Bochi-Layec, Ranjani Ramasubramanian, Shan Liu, Riemke Bouvier, Vitor Souza, Heta Patel, Ziyu Li, Alberto Carturan, Peter Michener, Caitlin Hopkins, Owen Koucky, Janna Minehart, Alex Dimitri, Neel Nabar, Zainul Hasanali, Bryan Ciccarelli, Erik Williams, Robert Bartoszek, Maya Lavorando, Suyash Mohan, Vanessa Gonzalez, Patrizia Porazzi, Vijay Bhoj, Sokratis Apostolidis, Dan Vogl, David Porter, John Scholler, Caroline Diorio, Aoife Doto, John Everett, Frederic Bushman, Katherine Nathanson, Edward Stadtmauer, Sandra Susanibar-Adaniya, Alfred Garfall, Marco Ruella, Adam Cohen, Joseph Fraietta
Journal: Blood
Blood (2025) 146 (Supplement 1): 804.
https://doi.org/10.1182/blood-2025-804
Published: 2025
Journal Articles

Phase 2 study of cevostamab consolidation following BCMA CAR T cell therapy:  preliminary safety, efficacy, and correlative data from the “STEM” (Sequential T Cell-Engagement for Myeloma) trial

Free
Adam Cohen, Sandra Susanibar-Adaniya, Alfred Garfall, Dan Vogl, Shivani Kapur, Adam Waxman, Danielle Zubka, Wei-Ting Hwang, Cynthia Diaczynsky, Julia Han Noll, Matthew Ho, Luca Paruzzo, Bing Yi, Rong Xu, Elina Thai, Vanessa Gonzalez, Peter Michener, Marco Ruella, Joseph Fraietta, Edward Stadtmauer
Journal: Blood
Blood (2025) 146 (Supplement 1): 699.
https://doi.org/10.1182/blood-2025-699
Published: 2025
Journal Articles

Chimeric antigen receptor T-cell therapy in patients with coexisting malignancy and autoimmune disease

Free
Luca Paruzzo, Riemke Bouvier, Bria Fulmer, Ivan Cohen, Elise Chong, Jakub Svoboda, Sunita Dwivedy Nasta, Daniel Landsburg, Vrutti Patel, Matthew Ho, Alberto Carturan, Federico Stella, Adam Waxman, Adam Cohen, Dan Vogl, Stefan Barta, Audrey Bochi-Layec, Patrizia Porazzi, Joseph Fraietta, Alfred Garfall, Vijay Bhoj, Edward Stadtmauer, David Porter, James Riley, Peter Merkel, Stephen Schuster, Jordan Carter, Sokratis Apostolidis, Sandra Susanibar-Adaniya, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 4543.
https://doi.org/10.1182/blood-2025-4543
Published: 2025
Journal Articles

Rebuilding immunity: Kinetics and clinical impact of immune reconstitution after CAR T-cell therapy in multiple myeloma

Free
Heta Patel, Luca Paruzzo, Oxana Megherea, Matthew Ho, Thomas Luo, Dan Vogl, Shivani Kapur, Adam Waxman, Federico Stella, Alberto Carturan, Martina Pucillo, Antonio Imparato, Edward Stadtmauer, Alfred Garfall, Adam Cohen, Marco Ruella, Sandra Susanibar-Adaniya
Journal: Blood
Blood (2025) 146 (Supplement 1): 3995.
https://doi.org/10.1182/blood-2025-3995
Published: 2025
Journal Articles

Patients with Monoclonal Gammopathy Have a High Rate of Second Symptomatic COVID-19 Infection Even after a Prior COVID-19 Infection and Vaccination

Free
Saurabh Zanwar, Matthew Ho, Francis K. Buadi, Sikander Ailawadhi, Jeremy T. Larsen, P. Leif Bergsagel, Moritz Binder, Asher Chanan-Khan, David Dingli, Angela Dispenzieri, Rafael Fonseca, Morie A. Gertz, Wilson I. Gonsalves, Ronald Go, Suzanne R. Hayman, Prashant Kapoor, Taxiarchis Kourelis, Martha Q. Lacy, Nelson Leung, Yi Lin, Eli Muchtar, Vivek Roy, Taimur Sher, Rahma M Warsame, Amie Fonder, Miriam A. Hobbs, Yi L. Hwa, Robert A. Kyle, S. Vincent Rajkumar, Shaji K Kumar
Journal: Blood
Blood (2022) 140 (Supplement 1): 10017–10019.
https://doi.org/10.1182/blood-2022-167181
Published: 2022
Journal Articles

Risk factors for severe infection and mortality in COVID-19 and monoclonal gammopathy of undetermined significance

Free
Matthew Ho, Saurabh Zanwar, Francis K. Buadi, Sikander Ailawadhi, Jeremy Larsen, Leif Bergsagel, Moritz Binder, Asher Chanan-Khan, David Dingli, Angela Dispenzieri, Rafael Fonseca, Morie A. Gertz, Wilson Gonsalves, Ronald S. Go, Suzanne Hayman, Prashant Kapoor, Taxiarchis Kourelis, Martha Q. Lacy, Nelson Leung, Yi Lin, Eli Muchtar, Vivek Roy, Taimur Sher, Rahma Warsame, Amie Fonder, Miriam Hobbs, Yi L. Hwa, Robert A. Kyle, S. Vincent Rajkumar, Shaji Kumar
Journal: Blood
Blood (2022) 140 (18): 1997–2000.
https://doi.org/10.1182/blood.2022017616
Published: 2022
Includes: Supplemental data
Journal Articles

Outcomes of Triple Class (Proteasome Inhibitor, IMiDs and Monoclonal Antibody) Refractory Patients with Multiple Myeloma

Free
Saurabh Zanwar, Matthew Ho, Prashant Kapoor, Angela Dispenzieri, Morie A. Gertz, Martha Q. Lacy, Francis K. Buadi, Suzanne R. Hayman, David Dingli, Taxiarchis Kourelis, Amie Fonder, Yi L. Hwa, Miriam A. Hobbs, Wilson I Gonsalves, Rahma M Warsame, Eli Muchtar, Nelson Leung, Robert A. Kyle, S. Vincent Rajkumar, Shaji Kumar
Journal: Blood
Blood (2021) 138 (Supplement 1): 1632.
https://doi.org/10.1182/blood-2021-145085
Published: 2021
Journal Articles

The Prognostic Impact of Abnormal Protein Bands in Multiple Myeloma: A Systematic Review and Meta-Analysis

Free
Soon Khai Low, Matthew Ho, Saad Jamshed
Journal: Blood
Blood (2021) 138 (Supplement 1): 4738.
https://doi.org/10.1182/blood-2021-151765
Published: 2021
Journal Articles

YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma

Free
Yan Xu, Mariateresa Fulciniti, Mehmet K. Samur, Matthew Ho, Shuhui Deng, Lanting Liu, Kenneth Wen, Tengteng Yu, Zuzana Chyra, Sanika Dereibal, Li Zhang, Yao Yao, Chandraditya Chakraborty, Eugenio Morelli, Na Li, Michael A. Lopez, Tommaso Perini, Shidai Mu, Gang An, Rafael Alonso, Giada Bianchi, Yu-Tzu Tai, Kenneth C. Anderson, Lugui Qiu, Nikhil C. Munshi
Journal: Blood
Blood (2020) 136 (4): 468–479.
https://doi.org/10.1182/blood.2019004147
Published: 2020
Includes: Supplemental data
Journal Articles

The Transmembrane Receptor Roundabout 1 (ROBO1) Is Necessary for Multiple Myeloma Proliferation and Homing to the Bone Marrow Niche

Free
Giada Bianchi, MD, Peter G. Czarnecki, MD, Matthew Ho, PhD, Aldo M. Roccaro, MD PhD, Antonio Sacco, RN, Yawara Kawano, MD PhD, Anil Aktas Samur, PhD, Annamaria Gulla, MD, Tianzeng Chen, Kenneth Wen, Xinchen Wu, Yu-Tzu Tai, PhD, Gulden Camci-Unal, PhD, Irene M. Ghobrial, MD, Ruben D. Carrasco, MD PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 507.
https://doi.org/10.1182/blood-2019-128778
Published: 2019
Journal Articles

Ywhae/14-3-3ε Expression Promotes Translation Initiation and Protein Synthesis in Multiple Myeloma Regulating Proteasome Load and Contributing to Proteasome Inhibitor Sensitivity/Resistance

Free
Yan Xu, MD, Matthew Ho, PhD, Mehmet Kemal Samur, PhD, Kenneth Wen, Shuhui Deng, MD, Lanting Liu, MD, Tengteng Yu, MD PhD, Zuzana Chyra, PhD, Sanika Derebail, Kenneth C. Anderson, MD, Lugui Qiu, MD PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5539.
https://doi.org/10.1182/blood-2019-130902
Published: 2019
Journal Articles

Dysregulated Translational Control Is a Central Feature of MM Mediated By 14-3-3ε Interactome Promoting Multiple Myeloma Cell Growth and Viability

Free
Yan Xu, MD, Mariateresa Fulciniti, PhD, Matthew Ho, Mehmet Kemal Samur, PhD, Michael A Lopez, Na Li, MD, Giada Bianchi, MD, Raphael Szalat, MD, Jianhong Lin, MD MSc, Tommaso Perini, MD, Srikanth Talluri, PhD, Tengteng Yu, MD, Kenneth Wen, BS, Jiye Liu, PhD, Li Zhang, MD, Liang Lin, PhD, Lijie Xing, MD, Gang An, MD, Yu-Tzu Tai, PhD, Kenneth Anderson, MD, Lugui Qiu, MD PhD, Nikhil Munshi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3176.
https://doi.org/10.1182/blood-2018-99-118994
Published: 2018
Journal Articles

Blocking HDAC3 in Bone Marrow Stromal Cells Has Direct Anti-Multiple Myeloma Effect and Modulates T Cell Function

Free
Matthew Ho, Jiye Liu, PhD, Alireza Kalbasi, PharmD, Takeshi Harada, MDPhD, Teru Hideshima, MD PhD, Paul Dowling, BSc, PhD, Yu-Tzu Tai, PhD, Li Zhang, MD, Kenneth Wen, BS, Ralph Mazitschek, Amanda McCann, Kenneth C Anderson, MD, Peter O'Gorman, MD PhD FRCP, FRCPath, Giada Bianchi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4429.
https://doi.org/10.1182/blood.V130.Suppl_1.4429.4429
Published: 2017
Journal Articles

Ywhae Located on Chromosome 17p13 Promotes Myeloma Cells Proliferation Via Induction of Anti-Apoptosis and Survival Signaling Pathways

Free
Yan Xu, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Raphael Szalat, MD, Matthew Ho, Michael A Lopez, BS, Na Li, MD, Jianhong Lin, MD MSc, Tommaso Perini, MD, Srikanth Talluri, PhD, Jiye Liu, PhD, Kenneth Wen, BS, Giada Bianchi, MD, Li Zhang, MD, Lijie Xing, MD, An Gang, MD, Liang Lin, PhD, Yu-Tzu Tai, PhD, Lugui Qiu, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1755.
https://doi.org/10.1182/blood.V130.Suppl_1.1755.1755
Published: 2017
Journal Articles

Novel Mechanisms Underlying IMiDs Resistance in Multiple Myeloma: Therapeutic Implications

Free
Jiye Liu, PhD, Wenrong Zhou, PhD, Lijie Xing, MD, Matthew Ho, Kenneth Wen, BS, Tianyu Song, Yu-Tzu Tai, PhD, Teru Hideshima, MD PhD, Yong Cang, PhD, Kenneth C Anderson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 594.
https://doi.org/10.1182/blood.V130.Suppl_1.594.594
Published: 2017
Journal Articles

Anti-Tumor Activities of XBP1 Antigen-Specific Cytotoxic T Lymphocytes Are Enhanced By HDAC6 Inhibitor ACY241

Free
Jooeun Bae, PhD, Matthew Ho, Brandon Nguyen, Arghya Ray, PhD, Dharminder Chauhan, PhD, Teru Hideshima, MD PhD, Nikhil Munshi, MD, Kenneth C Anderson, MD
Journal: Blood
Blood (2016) 128 (22): 2143.
https://doi.org/10.1182/blood.V128.22.2143.2143
Published: 2016
Journal Articles

Identification and Validation of HLA-A24 XBP1 us , XBP1 sp , CD138, and CS1 Peptides to Generate Antigens Specific-Cytotoxic T Lymphocytes: Preclinical Basis for Vaccine Therapy in HLA-A24 Patients with Multiple Myeloma and Other Cancers

Free
Jooeun Bae, PhD, Brandon Nguyen, Matthew Ho, Yan Song, PhD, Noopur Raje, MD, Paul G. Richardson, MD, Teru Hideshima, MD PhD, Dharminder Chauhan, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2016) 128 (22): 5689.
https://doi.org/10.1182/blood.V128.22.5689.5689
Published: 2016