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Luca Paruzzo
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Journal Articles

Efficacy and Safety of Anti-CD19 and Anti-BCMA Chimeric Antigen Receptor (CAR) T-Cell Therapies in Patients with Autoimmune Disease and Lymphoma or Myeloma

Luca Paruzzo, Riemke Bouvier, Guido Ghilardi, Eugenio Fardella, Bria Fulmer, Ivan J Cohen, Elise A. Chong, Jakub Svoboda, Sunita D. Nasta, Daniel J. Landsburg, Vrutti Patel, Li Ziyu, Raymone Pajarillo, Adam Waxman, Adam D. Cohen, Dan T. Vogl, Stefan K. Barta, Patrizia Porazzi, Joseph A. Fraietta, Vijay Bhoj, Alfred L. Garfall, Edward A. Stadtmauer, Stephen J. Schuster, Jordan S. Carter, Sokratis A. Apostolidis, Sandra Susanibar-Adaniya, Marco Ruella
Journal: Blood
Blood (2024) 144 (Supplement 1): 7243.
https://doi.org/10.1182/blood-2024-206608
Published: 2024
Journal Articles

Ketogenic Diet Enhances CAR T Cell Antitumor Function Via β-Hydroxybutyrate

Shan Liu, Puneeth Guruprasad, Kecheng Han, Luca Paruzzo, Alexander Shestov, Andre Kelly, Kevin R. Amses, Amichay Afriat, Bhoomi Madhu, Lev Litichevskiy, Ezra Dubowitz, Neil Tangal, Alana McSween, Melody Tan, Alberto Carturan, Andrew Lee, Yunlin Zhang, Giulia Gabrielli, Raymone Pajarillo, Ruchi P. Patel, Guido Ghilardi, Patrizia Porazzi, Stephen J. Schuster, Roddy S. O'Connor, Michael C. Milone, Joshua Rabinowitz, Maayan Levy, Marco Ruella
Journal: Blood
Blood (2024) 144 (Supplement 1): 4.
https://doi.org/10.1182/blood-2024-208913
Published: 2024
Journal Articles

EZH1/2 Inhibition Improves the Anti-Tumor Efficacy of CAR and TCR T-Cell Based Therapies Against Multiple Liquid and Solid Tumors

Siena Nason, Ziqi Yang, Guido Ghilardi, Luca Paruzzo, Alberto Carturan, Eugenio Fardella, Puneeth Guruprasad, Anushka Anant Padmanabhan, Tatiana Blanchard, Gerald Linette, Beatriz M. Carreno, Sandra Susanibar-Adaniya, Alfred L. Garfall, Marco Ruella, Patrizia Porazzi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4792.
https://doi.org/10.1182/blood-2024-206011
Published: 2024
Journal Articles

Access and Outcomes of Minority Health Populations Receiving Commercial Anti-BCMA CART Therapy for Multiple Myeloma

Luca Paruzzo, Khashayar Eshaghi, Guido Ghilardi, Abigail Doucette, Adam Waxman, Adam D. Cohen, Dan T. Vogl, Shivani Kapur, Eugenio Fardella, Alberto Carturan, Luke Maillie, Sofia Kaparis, Jalpa A. Doshi, Alfred L. Garfall, Edward A. Stadtmauer, Carmen E Guerra, Sandra Susanibar-Adaniya, Marco Ruella
Journal: Blood
Blood (2024) 144 (Supplement 1): 3779.
https://doi.org/10.1182/blood-2024-206544
Published: 2024
Journal Articles

Clinical Activity of Tisagenlecleucel in Large B Cell Lymphomas According to the 5 th Edition of the Who Classification

Guido Ghilardi, Emeline R. Chong, Luca Paruzzo, Giulia Gabrielli, Sunita D. Nasta, Vrutti Patel, Eugenio Fardella, Daniel J. Landsburg, Jordan Carter, Colin Thomas, Stefan K. Barta, Elise A. Chong, Jakub Svoboda, Marco Ruella, Stephen J. Schuster
Journal: Blood
Blood (2024) 144 (Supplement 1): 1750.
https://doi.org/10.1182/blood-2024-206027
Published: 2024
Journal Articles

CD19 CAR-T Cell Therapy Is Effective in Richter Transformation: A Multicenter Retrospective Analysis By the European Research Initiative on Chronic Lymphocytic Leukemia

Ofrat Beyar-Katz, Ohad Benjamini, Julio Delgado, Marco Ruella, Ron Ram, Sigal Grisariu, Andrea Visentin, Elisabeth Vandenberghe, Massimo Gentile, Abraham Avigdor, Avichai Shimoni, Roni Shouval, Ronit Marcus, Stephen J. Schuster, Valentin Ortiz-Maldonado, Guido Ghilardi, Luca Paruzzo, Tsila Zuckerman, Tamar Tadmor, Riva Fineman, Odelia Amit, Nuria Martinez-Cibrian, Giulia Gabrielli, Batia Avni, Eva Minga, Noga Shem-Tov, Lydia Scarfo, Ronit Yerushalmi, Arnon Nagler, Ronit Leiba, Ivetta Danylesko, Kostas Stamatopoulos, Thomas Chatzikonstantinou, Paolo Ghia, Yair Herishanu
Journal: Blood
Blood (2024) 144 (Supplement 1): 4504.
https://doi.org/10.1182/blood-2024-200050
Published: 2024
Journal Articles

Alternative splicing of its 5′-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

Zhiwei Ang, Luca Paruzzo, Katharina E. Hayer, Carolin Schmidt, Manuel Torres Diz, Feng Xu, Urvi Zankharia, Yunlin Zhang, Samantha Soldan, Sisi Zheng, Catherine D. Falkenstein, Joseph P. Loftus, Scarlett Y. Yang, Mukta Asnani, Patricia King Sainos, Vinodh Pillai, Emeline Chong, Marilyn M. Li, Sarah K. Tasian, Yoseph Barash, Paul M. Lieberman, Marco Ruella, Stephen J. Schuster, Andrei Thomas-Tikhonenko
Journal: Blood
Blood (2023) 142 (20): 1724–1739.
https://doi.org/10.1182/blood.2023020400
Published: 2023
Includes: Supplemental data
Journal Articles

A First-in-Human Phase I Study of AT101, a Novel Anti-CD19 Chimeric Antigen Receptor T Cell Product Targeting a Membrane-Proximal Domain of CD19 in Adults with Relapsed or Refractory B Cell Non-Hodgkin Lymphoma

Yunlin Zhang, Ruchi P. Patel, Ki Hyun Kim, Hyungwoo Cho, Jae-Cheol Cho, Seong Hyun Jeong, Sung Yong Oh, Yoon Seok Choi, Sung-Hyun Kim, Ji Hyun Lee, Mathew G. Angelos, Puneeth Guruprasad, Ivan J Cohen, Ositadimma Ugwuanyi, Yong Gu Lee, Raymone Pajarillo, Jong Hyun Cho, Alberto Carturan, Luca Paruzzo, Guido Ghilardi, Soohwan Kim, Sung Min Kim, Hyun Jong Lee, Ji Ho Park, Lei Guang Cui, Tae Bum Lee, Insik Hwang, Youngha Lee, Yong-Jun Lee, Patrizia Porazzi, Dongfang Liu, Yoon Lee, Jong Hoon Kim, Jong Seo Lee, Dok Hyun Yoon, Junho Chung, Marco Ruella
Journal: Blood
Blood (2023) 142 (Supplement 1): 2096.
https://doi.org/10.1182/blood-2023-189369
Published: 2023
Journal Articles

Bendamustine Is Less Toxic Than Fludarabine-Cyclophosphamide-Based Lymphodepletion before CD28-Costimulated CART19 through Reduced Inflammatory Cytokines

Guido Ghilardi, Luca Paruzzo, Jakub Svoboda, Elise A. Chong, Alexander Shestov, Linhui Chen, Ivan J Cohen, Giulia Gabrielli, Dwivedy S. Nasta, Patrizia Porazzi, Daniel J. Landsburg, James Gerson, Jordan Carter, Stefan K. Barta, Rebecca Yelton, Raymone Pajarillo, Griffin W White, Hatcher Ballard, Elizabeth Weber, Ellen B. Napier, Emeline R. Chong, Joseph A Fraietta, Alfred L. Garfall, David L. Porter, Michael C. Milone, Roderick O'Connor, Stephen J. Schuster, Marco Ruella
Journal: Blood
Blood (2023) 142 (Supplement 1): 4483.
https://doi.org/10.1182/blood-2023-182234
Published: 2023
Journal Articles

Modulation of the Btla-HVEM Axis to Enhance CAR T Cell Immunotherapy Against Cancer

Puneeth Guruprasad, Alberto Carturan, Yunlin Zhang, Kingsley Gideon Kumashie, Ivan J Cohen, Guido Ghilardi, Ki-Hyun Kim, Jong-Seo Lee, Yoon Lee, Jong-Hoon Kim, Junho Chung, Maksim Shestov, Raymone Pajarillo, Jaryse Harris, Yong Gu Lee, Michael Wang, Hatcher Ballard, Aasha Gupta, Ositadimma Ugwuanyi, Seok Jae Hong, Linhui Chen, Luca Paruzzo, Shane Kammerman, Ruchi P. Patel, Olga Shestova, Laura Vella, Stephen J. Schuster, Jakub Svoboda, Patrizia Porazzi, Marco Ruella
Journal: Blood
Blood (2023) 142 (Supplement 1): 768.
https://doi.org/10.1182/blood-2023-189633
Published: 2023
Journal Articles

Access and Outcomes of Minority Health Populations Receiving Commercial Anti-CD19 CART Therapy for Non-Hodgkin Lymphoma

Guido Ghilardi, Staci Williamson, Raymone Pajarillo, Luca Paruzzo, Linhui Chen, Connor Grady, Abigail Doucette, Eneida R Nemecek, Giulia Gabrielli, Stefan K. Barta, Jakub Svoboda, Elise A. Chong, Rebecca Yelton, Dwivedy S. Nasta, Daniel J. Landsburg, Ositadimma Ugwuanyi, Andy Chen, Levanto Schachter, Griffin W White, Hatcher Ballard, Elizabeth Weber, Cara Curley, David L. Porter, Alfred L. Garfall, Wei-Ting Hwang, Carmen E Guerra, Richard T Maziarz, Stephen J Schuster, Marco Ruella
Journal: Blood
Blood (2023) 142 (Supplement 1): 2416.
https://doi.org/10.1182/blood-2023-187524
Published: 2023
Journal Articles

Overcoming CD19-Negative Relapses in Patients with B-Cell Lymphomas Treated with Tisagenlecleucel

Guido Ghilardi, Yong Gu Lee, Patrizia Porazzi, Ivan Cohen, Luca Paruzzo, Ositadimma H Ugwuanyi, Raymone Pajarillo, Yunlin Zhang, Puneeth Guruprasad, Ruchi P. Patel, Elise A. Chong, Sunita Dwivedy Nasta, Stefan K. Barta, Alfred L. Garfall, Daniel J. Landsburg, Sam Sadigh, Mariusz Wasik, Jakub Svoboda, Siddharth Bhattacharyya, Stephen J. Schuster, Marco Ruella
Journal: Blood
Blood (2022) 140 (Supplement 1): 7371–7373.
https://doi.org/10.1182/blood-2022-167601
Published: 2022