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Mariusz Wasik
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Journal Articles

Inosine Monophosphate Dehydrogenase-2 (IMPDH2) As the Potential Novel Therapeutic Target in Mantle Cell Lymphoma (MCL): The Underlying Tyrosine Phosphorylation-Based Activation Mechanism and Translational Implications

Johnvesly Basappa, Shengchun Wang, Cosimo Lobello, David Rushmore, Olga Melnikov, Neil Sen, Vinay Mallikarjuna, Priyanka Jain, Pin Lu, Y. Lynn Wang, Kathy Cai, Reza Nejati, Aaron Goldman, Mariusz Wasik
Journal: Blood
Blood (2024) 144 (Supplement 1): 1602.
https://doi.org/10.1182/blood-2024-203257
Published: 2024
Journal Articles

Mitochondrial ACSS1 Regulates Oncometabolite 2-Hydroxyglutarate and De Novo Pyrimidine Biosynthesis in Lymphoma Cells: Functional Insights and Translational Implications

Johnvesly Basappa, Aaron Goldman, Cosimo Lobello, Shengchun Wang, David Rushmore, Pin Lu, Reza Nejati, Mariusz Wasik
Journal: Blood
Blood (2024) 144 (Supplement 1): 4120.
https://doi.org/10.1182/blood-2024-205334
Published: 2024
Journal Articles

DNA polymerase θ protects leukemia cells from metabolically induced DNA damage

Umeshkumar Vekariya, Monika Toma, Margaret Nieborowska-Skorska, Bac Viet Le, Marie-Christine Caron, Anna-Mariya Kukuyan, Katherine Sullivan-Reed, Paulina Podszywalow-Bartnicka, Kumaraswamy N. Chitrala, Jessica Atkins, Malgorzata Drzewiecka, Wanjuan Feng, Joe Chan, Srinivas Chatla, Konstantin Golovine, Jaroslav Jelinek, Tomasz Sliwinski, Jayashri Ghosh, Ksenia Matlawska-Wasowska, Gurushankar Chandramouly, Reza Nejati, Mariusz Wasik, Stephen M. Sykes, Katarzyna Piwocka, Emir Hadzijusufovic, Peter Valent, Richard T. Pomerantz, George Morton, Wayne Childers, Huaqing Zhao, Elisabeth M. Paietta, Ross L. Levine, Martin S. Tallman, Hugo F. Fernandez, Mark R. Litzow, Gaorav P. Gupta, Jean-Yves Masson, Tomasz Skorski
Journal: Blood
Blood (2023) 141 (19): 2372–2389.
https://doi.org/10.1182/blood.2022018428
Published: 2023
Includes: Supplemental data
Journal Articles

Overcoming CD19-Negative Relapses in Patients with B-Cell Lymphomas Treated with Tisagenlecleucel

Guido Ghilardi, Yong Gu Lee, Patrizia Porazzi, Ivan Cohen, Luca Paruzzo, Ositadimma H Ugwuanyi, Raymone Pajarillo, Yunlin Zhang, Puneeth Guruprasad, Ruchi P. Patel, Elise A. Chong, Sunita Dwivedy Nasta, Stefan K. Barta, Alfred L. Garfall, Daniel J. Landsburg, Sam Sadigh, Mariusz Wasik, Jakub Svoboda, Siddharth Bhattacharyya, Stephen J. Schuster, Marco Ruella
Journal: Blood
Blood (2022) 140 (Supplement 1): 7371–7373.
https://doi.org/10.1182/blood-2022-167601
Published: 2022
Journal Articles

Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms

Margaret Nieborowska-Skorska, Silvia Maifrede, Yashodhara Dasgupta, Katherine Sullivan, Sylwia Flis, Bac Viet Le, Martyna Solecka, Elizaveta A. Belyaeva, Lucia Kubovcakova, Morgan Nawrocki, Martin Kirschner, Huaqing Zhao, Josef T. Prchal, Katarzyna Piwocka, Alison R. Moliterno, Mariusz Wasik, Steffen Koschmieder, Tony R. Green, Radek C. Skoda, Tomasz Skorski
Journal: Blood
Blood (2017) 130 (26): 2848–2859.
https://doi.org/10.1182/blood-2017-05-784942
Published: 2017
Includes: Supplemental data
Journal Articles

Normal ABL1 Is a Tumor Suppressor and Therapeutic Target In BCR-ABL1–positive Leukemias

Yashodhara Dasgupta, Mateusz Koptyra, PhD, Margaret Nieborowska-Skorska, MD, PhD, Elisabeth Bolton Gillespie, PhD, Tomasz Stoklosa, MD, PhD, Grazyna Hoser, PhD, Mariusz Wasik, MD, Markus Muschen, Christine Richardson, PhD, Tomasz Skorski, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1466.
https://doi.org/10.1182/blood.V122.21.1466.1466
Published: 2013
Journal Articles

BCR/ABL→STAT5 Pathway Stimulates Helix-Loop-Helix Id-1 Protein To Enhance the MMP9 - Dependent Invasiveness of Leukemia Cells.

Margaret Nieborowska-Skorska, MD, PhD, Grazyna Hoser, PhD, Maciej Malecki, PhD, Mariusz Wasik, MD, PhD, Tomasz Skorski, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 2954.
https://doi.org/10.1182/blood.V104.11.2954.2954
Published: 2004
Journal Articles

STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

Christine Brender, Mette Nielsen, Keld Kaltoft, Gitte Mikkelsen, Qian Zhang, Mariusz Wasik, Nils Billestrup, Niels Ødum
Journal: Blood
Blood (2001) 97 (4): 1056–1062.
https://doi.org/10.1182/blood.V97.4.1056
Published: 2001
Journal Articles

Bcl-2 expression restores the leukemogenic potential of a BCR/ABL mutant defective in transformation

Maria Cirinnà, Rossana Trotta, Paolo Salomoni, Plamen Kossev, Mariusz Wasik, Danilo Perrotti, Bruno Calabretta
Journal: Blood
Blood (2000) 96 (12): 3915–3921.
https://doi.org/10.1182/blood.V96.12.3915
Published: 2000
Journal Articles

Role of p53 in Hematopoietic Recovery After Cytotoxic Treatment

Pawel Wlodarski, Mariusz Wasik, Mariusz Z. Ratajczak, Cinzia Sevignani, Grazyna Hoser, Jerzy Kawiak, Alan M. Gewirtz, Bruno Calabretta, Thomas Skorski
Journal: Blood
Blood (1998) 91 (8): 2998–3006.
https://doi.org/10.1182/blood.V91.8.2998.2998_2998_3006
Published: 1998
Journal Articles

The SH3 Domain Contributes to BCR/ABL-Dependent Leukemogenesis In Vivo: Role in Adhesion, Invasion, and Homing

Tomasz Skorski, Malgorzata Nieborowska-Skorska, Pawel Wlodarski, Mariusz Wasik, Rossana Trotta, Palanisamy Kanakaraj, Paolo Salomoni, Mark Antonyak, Robert Martinez, Miroslaw Majewski, Albert Wong, Bice Perussia, Bruno Calabretta
Journal: Blood
Blood (1998) 91 (2): 406–418.
https://doi.org/10.1182/blood.V91.2.406
Published: 1998