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Journal Articles

Separation of B- and T-Cell-Specific Signaling Molecules Prevents Oncogenic Transformation in Lymphoid Malignancies

Franz Ketzer, Lars Klemm, Mark E Robinson, Christian Loucks, David Fonseca Arce, Kadriye Nehir Cosgun, Shalin Kothari, Markus Müschen

Blood (2023) 142 (Supplement 1): 1396.

https://doi.org/10.1182/blood-2023-189221

Published: 2023

Journal Articles

PTEN Counter Balances mTORC1 and PI3K Activities to Maintain Metabolic Homeostasis of B-ALL

Huimin Liu, Junzhe Song, Mark E Robinson, Gang Xiao, Markus Müschen

Blood (2023) 142 (Supplement 1): 2780.

https://doi.org/10.1182/blood-2023-184800

Published: 2023

Journal Articles

MYC to BCL6 State-Transitions Determine Cell Size and Metabolic Fluctuations and Define a Novel Biorhythm in B-Cell Malignancies

Zhangliang Cheng, Kohei Kume, Markus Müschen

Blood (2023) 142 (Supplement 1): 2769.

https://doi.org/10.1182/blood-2023-190972

Published: 2023

Journal Articles

Dynamic Recruitment of Inhibitory Complexes Controls Oncogenic Signaling in B-Cell Malignancies

Ruifeng Sun, Jaewoong Lee, Mark E Robinson, Kohei Kume, Ning Ma, Kadriye Nehir Cosgun, Lai N Chan, Irina Antoshkina, Dhruv Khanduja, Etienne Leveille, Samuel G. Katz, Jianjun Chen, Elisabeth Paietta, Nagarajan Vaidehi, Markus Müschen

Blood (2023) 142 (Supplement 1): 719.

https://doi.org/10.1182/blood-2023-189742

Published: 2023

Journal Articles

STAT5-Feedback Controls Distinct Metabolic States for Dynamic Transitions between Cellular Activation and Quiescence in Acute Lymphoblastic Leukemia

Kohei Kume, Zhengshan Chen, Mark E Robinson, Lai N Chan, Etienne Leveille, Kadriye Nehir Cosgun, Zhangliang Cheng, David Fonseca Arce, Dhruv Khanduja, Thomas Graeber, Markus Müschen

Blood (2023) 142 (Supplement 1): 2977.

https://doi.org/10.1182/blood-2023-191006

Published: 2023

Journal Articles

Mechanistic Elucidation of the Tumor-Promoting Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 in B-Cell Receptor Signaling in Mantle Cell Lymphoma

Serene Xavier, Vivian Nguyen, Vishal Khairnar, An Phan, Lu Yang, Michael Nelson, Elizabeth Tseng, Aimin Li, Joo Y Song, Dennis D. Weisenburger, Wing C. Chan, Markus Müschen, Vu N. Ngo

Blood (2023) 142 (Supplement 1): 720.

https://doi.org/10.1182/blood-2023-175064

Published: 2023

Journal Articles

The Transcriptional Landscape of Ph+B-ALL Is Orchestrated By Long-Range Enhancer-Promoter Interactions and the Coordinated Action of Phosphorylation-Dependent and Phosphorylation-Independent Transcription Factors

Han Leng Ng, Mark E Robinson, Valeria Malysheva, Ozgen Deniz, Nicholas Crump, Kadriye Nehir Cosgun, Kaiyue Helian, Mikhail Spivakov, Markus Müschen, Niklas Feldhahn

Blood (2023) 142 (Supplement 1): 2779.

https://doi.org/10.1182/blood-2023-173435

Published: 2023

Journal Articles

Optogenetic Control of Oncogenic Signaling in B-Cell Malignancies

Kohei Kume, Jaewoong Lee, Zhangliang Cheng, Mark E Robinson, Etienne Leveille, Kadriye Nehir Cosgun, Lai N Chan, Yanzhi Feng, David Fonseca Arce, Dhruv Khanduja, Derek Toomre, Markus Müschen

Blood (2023) 142 (Supplement 1): 4138.

https://doi.org/10.1182/blood-2023-190926

Published: 2023

Journal Articles

Immunoglobulin Light Chains Control Permissiveness to Malignant B-Cell Transformation By RAS-Pathway Lesions

Lai N Chan, Kohei Kume, Christian Hurtz, Mark E Robinson, Kadriye Nehir Cosgun, Markus Müschen

Blood (2023) 142 (Supplement 1): 2974.

https://doi.org/10.1182/blood-2023-190163

Published: 2023

Journal Articles

Development of Chimeric Antigen Receptor (CAR) T Cells Targeting MET in Lymphomas and Solid Tumors

Pohan Chen, Rianna Raghunandan, Markus Müschen, Samuel G. Katz

Blood (2023) 142 (Supplement 1): 6805.

https://doi.org/10.1182/blood-2023-186161

Published: 2023

Journal Articles

Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies

Blood (2023) 142 (Supplement 1): 2818.

https://doi.org/10.1182/blood-2023-190522

Published: 2023

Journal Articles

Computational Discovery and Validation of NAD+ Biosynthesis As Unique Vulnerability in B-Lymphoid Malignancies

Qin Li, Mark E Robinson, Etienne Leveille, Chang Zhang, Ruifeng Sun, Zhangliang Cheng, Kohei Kume, Kadriye Nehir Cosgun, Shalin Kothari, Dhruv Khanduja, Daisuke Nakada, Markus Müschen

Blood (2023) 142 (Supplement 1): 418.

https://doi.org/10.1182/blood-2023-190269

Published: 2023

Journal Articles

Genetic Knockin Approaches to Reconstructing DLBCL-Subtypes from Human Germinal Center B-Cells

Dhruv Khanduja, Mark E Robinson, David Fonseca Arce, Lars Klemm, Etienne Leveille, Shalin Kothari, Rebecca Caeser, Daniel James Hodson, Markus Müschen

Blood (2023) 142 (Supplement 1): 1627.

https://doi.org/10.1182/blood-2023-190634

Published: 2023

Journal Articles

Structural Elements of the BCR Determine Permissiveness to Oncogenic RAS-Driven B-Cell Transformation

Lai N. Chan, Mark E. Robinson, Kadriye Nehir Cosgun, Xiaohui Yu, Etienne Leveille, Huimin Geng, Markus Müschen

Blood (2022) 140 (Supplement 1): 8758–8759.

https://doi.org/10.1182/blood-2022-170079

Published: 2022

Journal Articles

Divergent MYC- and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell Malignancies

Kohei Kume, Zhengshan Chen, Lai N. Chan, Mark E. Robinson, Etienne Leveille, Jaewoong Lee, Kadriye Nehir Cosgun, David Fonseca Arce, Dhruv Khanduja, Lars Klemm, Markus Müschen

Blood (2022) 140 (Supplement 1): 5900–5901.

https://doi.org/10.1182/blood-2022-170396

Published: 2022

Journal Articles

IFITM3 Acts As a PIP 3 Scaffold in TCR-PI3K Signaling

Andrew Takeda, Jaewoong Lee, Tim Wartewig, Alberto Bigogno, David Fonseca Arce, Markus Müschen

Blood (2022) 140 (Supplement 1): 3030–3031.

https://doi.org/10.1182/blood-2022-170540

Published: 2022

Journal Articles

Repressive β-Catenin-Ikaros Complexes Are Essential to Prevent Clonal Evolution of Human Lymphopoiesis

Kadriye Nehir Cosgun, Wei Liu, Mark E. Robinson, David Fonseca Arce, Jennifer VanOudenhove, Alberto Bigogno, Richard Flavell, Stephanie Halene, Markus Müschen

Blood (2022) 140 (Supplement 1): 8744–8745.

https://doi.org/10.1182/blood-2022-170409

Published: 2022

Journal Articles

CD25 As Feedback Regulator of Oncogenic TCR Signaling in T-Cell Lymphoma

Ruifeng Sun, Jaewoong Lee, Tim Wartewig, Mark E. Robinson, Alberto Bigogno, David Fonseca Arce, Abu-Sayeef Mirza, Andrew Takeda, Lars Klemm, Vivasvan Vykunta, Brian Shy, Alexander Marson, Markus Müschen

Blood (2022) 140 (Supplement 1): 5975–5976.

https://doi.org/10.1182/blood-2022-170076

Published: 2022

Journal Articles

BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation

Lai N. Chan, Christian Hurtz, Mark E. Robinson, Etienne Leveille, Huimin Geng, Rebecca Caeser, Liang Xu, Kohei Kume, Gang Xiao, Markus Müschen

Blood (2022) 140 (Supplement 1): 9177–9178.

https://doi.org/10.1182/blood-2022-169946

Published: 2022

Journal Articles

GSK3β Inhibition Is a Unique Vulnerability in Lymphoid Malignancies

Kadriye Nehir Cosgun, Huda Jumaa, Mark E. Robinson, Lai N. Chan, Jaewoong Lee, Kohei Kume, David Fonseca Arce, Julia Jellusova, Markus Müschen

Blood (2022) 140 (Supplement 1): 3114–3115.

https://doi.org/10.1182/blood-2022-169961

Published: 2022

NARROW

Separation of B- and T-Cell-Specific Signaling Molecules Prevents Oncogenic Transformation in Lymphoid Malignancies

PTEN Counter Balances mTORC1 and PI3K Activities to Maintain Metabolic Homeostasis of B-ALL

MYC to BCL6 State-Transitions Determine Cell Size and Metabolic Fluctuations and Define a Novel Biorhythm in B-Cell Malignancies

Dynamic Recruitment of Inhibitory Complexes Controls Oncogenic Signaling in B-Cell Malignancies

STAT5-Feedback Controls Distinct Metabolic States for Dynamic Transitions between Cellular Activation and Quiescence in Acute Lymphoblastic Leukemia

Mechanistic Elucidation of the Tumor-Promoting Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 in B-Cell Receptor Signaling in Mantle Cell Lymphoma

The Transcriptional Landscape of Ph+B-ALL Is Orchestrated By Long-Range Enhancer-Promoter Interactions and the Coordinated Action of Phosphorylation-Dependent and Phosphorylation-Independent Transcription Factors

Optogenetic Control of Oncogenic Signaling in B-Cell Malignancies

Immunoglobulin Light Chains Control Permissiveness to Malignant B-Cell Transformation By RAS-Pathway Lesions

Development of Chimeric Antigen Receptor (CAR) T Cells Targeting MET in Lymphomas and Solid Tumors

Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies

Computational Discovery and Validation of NAD+ Biosynthesis As Unique Vulnerability in B-Lymphoid Malignancies

Genetic Knockin Approaches to Reconstructing DLBCL-Subtypes from Human Germinal Center B-Cells

Structural Elements of the BCR Determine Permissiveness to Oncogenic RAS-Driven B-Cell Transformation

Divergent MYC- and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell Malignancies

IFITM3 Acts As a PIP 3 Scaffold in TCR-PI3K Signaling

Repressive β-Catenin-Ikaros Complexes Are Essential to Prevent Clonal Evolution of Human Lymphopoiesis

CD25 As Feedback Regulator of Oncogenic TCR Signaling in T-Cell Lymphoma

BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation

GSK3β Inhibition Is a Unique Vulnerability in Lymphoid Malignancies

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American Society of Hematology

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ASH Publications

American Society of Hematology

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