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Journal Articles

Targeting β-Catenin Protein Degradation in Refractory B-Cell Malignancies

Kadriye Nehir Cosgun, Mark E Robinson, Nikol Agadzhanian, Philipp Berning, David Fonseca-Arce, Etienne Leveille, Shalin Kothari, Matthew S. Davids, Julia Jellusova, Markus Müschen

Blood (2024) 144 (Supplement 1): 1412.

https://doi.org/10.1182/blood-2024-208598

Published: 2024

Journal Articles

Metabolic Determinants of Ferroptosis in B-Cell Lymphoma

Etienne Leveille, Eden Bramson, Mark E Robinson, Thierry Bertomeu, Andrew Chatr-Aryamontri, Shalin Kothari, Markus Müschen

Blood (2024) 144 (Supplement 1): 976.

https://doi.org/10.1182/blood-2024-209077

Published: 2024

Journal Articles

Mechanism of Negative Feedback Regulation of Oncogenic BCR-Signaling in Mature B-Cell Lymphoma

Ruifeng Sun, Jaewoong Lee, Mark E Robinson, Kohei Kume, Chuanzong Zhan, Zhangliang Cheng, Kadriye Nehir Cosgun, Lai N Chan, Etienne Leveille, Shalin Kothari, Samuel G. Katz, Ning Ma, Vivasvan S Vykunta, Brian Shy, Daniel J Hodson, Alexander Marson, Nagarajan Vaidehi, Markus Müschen

Blood (2024) 144 (Supplement 1): 3003.

https://doi.org/10.1182/blood-2024-211693

Published: 2024

Journal Articles

PKCδ-Mediated Phosphorylation of CD25 Initiates Feedback Control of Oncogenic Tyrosine Kinases in Acute Lymphoblastic Leukemia

Ruifeng Sun, Jaewoong Lee, Dewan Artadji, Mark E Robinson, Kohei Kume, Zhangliang Cheng, Kadriye Nehir Cosgun, Lai N Chan, Etienne Leveille, Ning Ma, Huimin Geng, Elisabeth Paietta, Nagarajan Vaidehi, Markus Müschen

Blood (2024) 144 (Supplement 1): 632.

https://doi.org/10.1182/blood-2024-211038

Published: 2024

Journal Articles

STAT5-Feedback Controls Distinct Metabolic States for Dynamic Transitions between Cellular Activation and Quiescence in Acute Lymphoblastic Leukemia

Kohei Kume, Zhengshan Chen, Mark E Robinson, Lai N Chan, Etienne Leveille, Kadriye Nehir Cosgun, Zhangliang Cheng, David Fonseca Arce, Dhruv Khanduja, Thomas Graeber, Markus Müschen

Blood (2023) 142 (Supplement 1): 2977.

https://doi.org/10.1182/blood-2023-191006

Published: 2023

Journal Articles

Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies

Blood (2023) 142 (Supplement 1): 2818.

https://doi.org/10.1182/blood-2023-190522

Published: 2023

Journal Articles

Computational Discovery and Validation of NAD+ Biosynthesis As Unique Vulnerability in B-Lymphoid Malignancies

Qin Li, Mark E Robinson, Etienne Leveille, Chang Zhang, Ruifeng Sun, Zhangliang Cheng, Kohei Kume, Kadriye Nehir Cosgun, Shalin Kothari, Dhruv Khanduja, Daisuke Nakada, Markus Müschen

Blood (2023) 142 (Supplement 1): 418.

https://doi.org/10.1182/blood-2023-190269

Published: 2023

Journal Articles

Optogenetic Control of Oncogenic Signaling in B-Cell Malignancies

Kohei Kume, Jaewoong Lee, Zhangliang Cheng, Mark E Robinson, Etienne Leveille, Kadriye Nehir Cosgun, Lai N Chan, Yanzhi Feng, David Fonseca Arce, Dhruv Khanduja, Derek Toomre, Markus Müschen

Blood (2023) 142 (Supplement 1): 4138.

https://doi.org/10.1182/blood-2023-190926

Published: 2023

Journal Articles

Genetic Knockin Approaches to Reconstructing DLBCL-Subtypes from Human Germinal Center B-Cells

Dhruv Khanduja, Mark E Robinson, David Fonseca Arce, Lars Klemm, Etienne Leveille, Shalin Kothari, Rebecca Caeser, Daniel James Hodson, Markus Müschen

Blood (2023) 142 (Supplement 1): 1627.

https://doi.org/10.1182/blood-2023-190634

Published: 2023

Journal Articles

Dynamic Recruitment of Inhibitory Complexes Controls Oncogenic Signaling in B-Cell Malignancies

Ruifeng Sun, Jaewoong Lee, Mark E Robinson, Kohei Kume, Ning Ma, Kadriye Nehir Cosgun, Lai N Chan, Irina Antoshkina, Dhruv Khanduja, Etienne Leveille, Samuel G. Katz, Jianjun Chen, Elisabeth Paietta, Nagarajan Vaidehi, Markus Müschen

Blood (2023) 142 (Supplement 1): 719.

https://doi.org/10.1182/blood-2023-189742

Published: 2023

Journal Articles

CAR T-Related Toxicities Based on Dynamic Proteomic Profiles Identifies Risk Factors for Cytokine Release Syndrome (CRS) and Immune Effector Cell -Associated Neurotoxicity Syndrome (ICANS)

Tariq Kewan, Sayeef Mirza, Alexander B Pine, Yusuf Rasheed, Ramzi Hamouche, Etienne Leveille, George Goshua, Sean X Gu, Yuxin Liu, Jennifer Vanoudenhove, Noffar Bar, Natalia Neparidze, Francine M. Foss, Lohith Gowda, Iris Isufi, Stephanie Halene, Alfred I Lee, Stuart Seropian

Blood (2023) 142 (Supplement 1): 2132.

https://doi.org/10.1182/blood-2023-187295

Published: 2023

Journal Articles

Proteomic Profiles of Cytokine Release Syndromes Following Lisocabtagene Maraleucel and Idecabtagene Vicleucel

Abu-Sayeef Mirza, Alexander Pine, Yusuf Rasheed, Ramzi Hamouche, Etienne Leveille, George Goshua, Sean Gu, Yuxin Liu, Jennifer VanOudenhove, Noffar Bar, Natalia Neparidze, Francine M. Foss, Lohith Gowda, Iris Isufi, Stephanie Halene, Alfred I Lee, Stuart Seropian

Blood (2022) 140 (Supplement 1): 10410–10412.

https://doi.org/10.1182/blood-2022-168374

Published: 2022

Journal Articles

A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling

Blood (2022) 140 (Supplement 1): 1698–1699.

https://doi.org/10.1182/blood-2022-170324

Published: 2022

Journal Articles

Divergent MYC- and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell Malignancies

Kohei Kume, Zhengshan Chen, Lai N. Chan, Mark E. Robinson, Etienne Leveille, Jaewoong Lee, Kadriye Nehir Cosgun, David Fonseca Arce, Dhruv Khanduja, Lars Klemm, Markus Müschen

Blood (2022) 140 (Supplement 1): 5900–5901.

https://doi.org/10.1182/blood-2022-170396

Published: 2022

Journal Articles

Structural Elements of the BCR Determine Permissiveness to Oncogenic RAS-Driven B-Cell Transformation

Lai N. Chan, Mark E. Robinson, Kadriye Nehir Cosgun, Xiaohui Yu, Etienne Leveille, Huimin Geng, Markus Müschen

Blood (2022) 140 (Supplement 1): 8758–8759.

https://doi.org/10.1182/blood-2022-170079

Published: 2022

Journal Articles

BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation

Lai N. Chan, Christian Hurtz, Mark E. Robinson, Etienne Leveille, Huimin Geng, Rebecca Caeser, Liang Xu, Kohei Kume, Gang Xiao, Markus Müschen

Blood (2022) 140 (Supplement 1): 9177–9178.

https://doi.org/10.1182/blood-2022-169946

Published: 2022

Journal Articles

Beta-Catenin Forms Repressive Complexes with Ikzf1 and Ikzf3 to Orchestrate Tumor-Suppression in B-Cell Malignancies

Kadriye Nehir Cosgun, Mark E. Robinson, Lai N. Chan, Matthew Hur, Etienne Leveille, Joo Song, Wing (John) C. Chan, Markus Müschen

Blood (2021) 138 (Supplement 1): 29.

https://doi.org/10.1182/blood-2021-148597

Published: 2021

Journal Articles

Identification of BCL6 As Synthetic Lethality in RAS-Driven B-Cell Transformation

Lai N. Chan, Christian Hurtz, Etienne Leveille, Kohei Kume, Mark E. Robinson, Huimin Geng, Kadriye Nehir Cosgun, Markus Müschen

Blood (2021) 138 (Supplement 1): 792.

https://doi.org/10.1182/blood-2021-148653

Published: 2021

NARROW

Targeting β-Catenin Protein Degradation in Refractory B-Cell Malignancies

Metabolic Determinants of Ferroptosis in B-Cell Lymphoma

Mechanism of Negative Feedback Regulation of Oncogenic BCR-Signaling in Mature B-Cell Lymphoma

PKCδ-Mediated Phosphorylation of CD25 Initiates Feedback Control of Oncogenic Tyrosine Kinases in Acute Lymphoblastic Leukemia

STAT5-Feedback Controls Distinct Metabolic States for Dynamic Transitions between Cellular Activation and Quiescence in Acute Lymphoblastic Leukemia

Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies

Computational Discovery and Validation of NAD+ Biosynthesis As Unique Vulnerability in B-Lymphoid Malignancies

Optogenetic Control of Oncogenic Signaling in B-Cell Malignancies

Genetic Knockin Approaches to Reconstructing DLBCL-Subtypes from Human Germinal Center B-Cells

Dynamic Recruitment of Inhibitory Complexes Controls Oncogenic Signaling in B-Cell Malignancies

CAR T-Related Toxicities Based on Dynamic Proteomic Profiles Identifies Risk Factors for Cytokine Release Syndrome (CRS) and Immune Effector Cell -Associated Neurotoxicity Syndrome (ICANS)

Proteomic Profiles of Cytokine Release Syndromes Following Lisocabtagene Maraleucel and Idecabtagene Vicleucel

A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling

Divergent MYC- and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell Malignancies

Structural Elements of the BCR Determine Permissiveness to Oncogenic RAS-Driven B-Cell Transformation

BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation

Beta-Catenin Forms Repressive Complexes with Ikzf1 and Ikzf3 to Orchestrate Tumor-Suppression in B-Cell Malignancies

Identification of BCL6 As Synthetic Lethality in RAS-Driven B-Cell Transformation

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American Society of Hematology

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American Society of Hematology

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