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Zhangliang Cheng
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Journal Articles

PKCδ-Mediated Phosphorylation of CD25 Initiates Feedback Control of Oncogenic Tyrosine Kinases in Acute Lymphoblastic Leukemia

Ruifeng Sun, Jaewoong Lee, Dewan Artadji, Mark E Robinson, Kohei Kume, Zhangliang Cheng, Kadriye Nehir Cosgun, Lai N Chan, Etienne Leveille, Ning Ma, Huimin Geng, Elisabeth Paietta, Nagarajan Vaidehi, Markus Müschen
Journal: Blood
Blood (2024) 144 (Supplement 1): 632.
https://doi.org/10.1182/blood-2024-211038
Published: 2024
Journal Articles

Identification of High-Efficiency β-Catenin Protein Degradation As Critical Vulnerability in B-Cell Malignancies

Kadriye Nehir Cosgun, Mark E Robinson, Nikol Agadzhanian, Zhangliang Cheng, Salim Oulghazi, Philipp Berning, David Fonseca-Arce, Kohei Kume, Jake Fontaine, Lai N Chan, Jaewoong Lee, Fang Yu, Zhijian Qian, Joo Y. Song, Wing Chung Chan, Jianjun Chen, Mark M Taketo, Hilde Schjerven, Markus Müschen
Journal: Blood
Blood (2024) 144 (Supplement 1): 4125.
https://doi.org/10.1182/blood-2024-208125
Published: 2024
Journal Articles

Cell Growth Trajectories of B-Cell Lymphomas Are Defined By Oscillations between MYC- and BCL6-Dependent States

Zhangliang Cheng, Kohei Kume, Vignesh Shanmugam, Markus Müschen
Journal: Blood
Blood (2024) 144 (Supplement 1): 45.
https://doi.org/10.1182/blood-2024-206563
Published: 2024
Journal Articles

Identification of Nuclear NAD+ Salvage As a Therapeutic Vulnerability in B-Lymphoid Malignancies

Mark E Robinson, Qin Li, Chang Zhang, Chuanzong Zhan, Zhangliang Cheng, Kohei Kume, Kadriye Nehir Cosgun, Shalin Kothari, Nikol Agadzhanian, Daisuke Nakada, Markus Müschen
Journal: Blood
Blood (2024) 144 (Supplement 1): 4164.
https://doi.org/10.1182/blood-2024-205729
Published: 2024
Journal Articles

Mechanism of Negative Feedback Regulation of Oncogenic BCR-Signaling in Mature B-Cell Lymphoma

Ruifeng Sun, Jaewoong Lee, Mark E Robinson, Kohei Kume, Chuanzong Zhan, Zhangliang Cheng, Kadriye Nehir Cosgun, Lai N Chan, Etienne Leveille, Shalin Kothari, Samuel G. Katz, Ning Ma, Vivasvan S Vykunta, Brian Shy, Daniel J Hodson, Alexander Marson, Nagarajan Vaidehi, Markus Müschen
Journal: Blood
Blood (2024) 144 (Supplement 1): 3003.
https://doi.org/10.1182/blood-2024-211693
Published: 2024
Journal Articles

MYC to BCL6 State-Transitions Determine Cell Size and Metabolic Fluctuations and Define a Novel Biorhythm in B-Cell Malignancies

Zhangliang Cheng, Kohei Kume, Markus Müschen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2769.
https://doi.org/10.1182/blood-2023-190972
Published: 2023
Journal Articles

STAT5-Feedback Controls Distinct Metabolic States for Dynamic Transitions between Cellular Activation and Quiescence in Acute Lymphoblastic Leukemia

Kohei Kume, Zhengshan Chen, Mark E Robinson, Lai N Chan, Etienne Leveille, Kadriye Nehir Cosgun, Zhangliang Cheng, David Fonseca Arce, Dhruv Khanduja, Thomas Graeber, Markus Müschen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2977.
https://doi.org/10.1182/blood-2023-191006
Published: 2023
Journal Articles

Computational Discovery and Validation of NAD+ Biosynthesis As Unique Vulnerability in B-Lymphoid Malignancies

Qin Li, Mark E Robinson, Etienne Leveille, Chang Zhang, Ruifeng Sun, Zhangliang Cheng, Kohei Kume, Kadriye Nehir Cosgun, Shalin Kothari, Dhruv Khanduja, Daisuke Nakada, Markus Müschen
Journal: Blood
Blood (2023) 142 (Supplement 1): 418.
https://doi.org/10.1182/blood-2023-190269
Published: 2023
Journal Articles

Optogenetic Control of Oncogenic Signaling in B-Cell Malignancies

Kohei Kume, Jaewoong Lee, Zhangliang Cheng, Mark E Robinson, Etienne Leveille, Kadriye Nehir Cosgun, Lai N Chan, Yanzhi Feng, David Fonseca Arce, Dhruv Khanduja, Derek Toomre, Markus Müschen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4138.
https://doi.org/10.1182/blood-2023-190926
Published: 2023