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Daisuke Nakada
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Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney D. DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z. Orlowski, Muzaffar H. Qazilbash, Kapil N. Bhalla, Simona Colla, Hagop M. Kantarjian, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Daisuke Nakada, Jeffrey J. Molldrem, Gheath Alatrash, Andrew Futreal, Elizabeth J. Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 346.
https://doi.org/10.1182/blood-2024-208106
Published: 2024
Journal Articles

Identification of Nuclear NAD+ Salvage As a Therapeutic Vulnerability in B-Lymphoid Malignancies

Mark E Robinson, Qin Li, Chang Zhang, Chuanzong Zhan, Zhangliang Cheng, Kohei Kume, Kadriye Nehir Cosgun, Shalin Kothari, Nikol Agadzhanian, Daisuke Nakada, Markus Müschen
Journal: Blood
Blood (2024) 144 (Supplement 1): 4164.
https://doi.org/10.1182/blood-2024-205729
Published: 2024
Journal Articles

Purine Metabolism Modulates Leukemia Stem Cell Maintenance in MLL-Rearranged Acute Leukemia

Xiangguo Shi, Minhua Li, Lin Tan, Zian Liu, Yudan Zhu, Tiessen Jonathan, Jing Zhou, Mengdie Feng, Yuki Kageyama, Hassan Samee, Kristen Andreozzi, Philip Lorenzi, Koichi Takahashi, Michalis Agathocleous, Daisuke Nakada
Journal: Blood
Blood (2023) 142 (Supplement 1): 582.
https://doi.org/10.1182/blood-2023-190833
Published: 2023
Journal Articles

Computational Discovery and Validation of NAD+ Biosynthesis As Unique Vulnerability in B-Lymphoid Malignancies

Qin Li, Mark E Robinson, Etienne Leveille, Chang Zhang, Ruifeng Sun, Zhangliang Cheng, Kohei Kume, Kadriye Nehir Cosgun, Shalin Kothari, Dhruv Khanduja, Daisuke Nakada, Markus Müschen
Journal: Blood
Blood (2023) 142 (Supplement 1): 418.
https://doi.org/10.1182/blood-2023-190269
Published: 2023
Journal Articles

Targeting ADSS2 Enhances BH3 Mimetics Treatment Induced Mitochondrial Apoptosis in AML Cells

Xin He, Lei Zhang, Yang Li, Haojie Dong, Lianjun Zhang, Daisuke Nakada, Guido Marcucci, Yun Luo, Ling Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 577.
https://doi.org/10.1182/blood-2023-186907
Published: 2023
Journal Articles

Clonal Competition: Cisplatin Treatment Drives Dominance of TP53- over Tet2-Mutant Stem Cell Clones

Katharina Wohlan, Lorenzo Brunetti, Joanne I. Hsu, Katie A. Matatall, Rebecca L. Murdaugh, Linda Zhang, Anna Guzman, Jack Toups, Daniel Hormaechea-Agulla, Carina Rosas, Meghan Kisiel, Ayumi Kitano, Tianyuan Hu, Yu-Jung Tseng, Bailee N. Kain, Sara Biesiadny, Jonathan Tiessen, Minhua Li, Marcus Florez, Sarah Waldvogel, Kristen Kurtz, Mira Jeong, Duy Le, Daniel E. Morales-Mantilla, Hannah Yan, Alejandra Garcia Martell, Chiraag D. Kapadia, Yung-Hsin Huang, Shannon E. Conneely, Rogelio Aguilar, Xiangguo Shi, Tianpeng Gu, Hyojeong Han, Yajian Jiang, Jason Rogers, Taishi Yonezawa, Apoorva Thatavarty, Ruoqiong Cao, Trisha K. Wathan, Nesa Mercer, Daniel Kennedy, Ayala Tovy, Jaime M. Reyes, Marek Kimmel, Yun Huang, Daisuke Nakada, Katherine Y. King, Margaret A. Goodell
Journal: Blood
Blood (2022) 140 (Supplement 1): 8590–8591.
https://doi.org/10.1182/blood-2022-164858
Published: 2022
Journal Articles

AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia

Yajian Jiang, Tianyuan Hu, Tao Wang, Xiangguo Shi, Ayumi Kitano, Kenneth Eagle, Kevin A. Hoegenauer, Marina Y. Konopleva, Charles Y. Lin, Nicolas L. Young, Daisuke Nakada
Journal: Blood
Blood (2019) 134 (24): 2183–2194.
https://doi.org/10.1182/blood.2019001076
Published: 2019
Includes: Supplemental data
Journal Articles

Hematopoietic Hierarchy Under Steady-State and Stress Conditions

Yu-Jung Tseng, BS,MS, Richard Chapple, PhD, Tianyuan Hu, PhD, Kimal Rajapakshe, Kevin Hoegenauer, BS, Cristian Coarfa, PhD, Daisuke Nakada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1181.
https://doi.org/10.1182/blood-2019-125110
Published: 2019
Journal Articles

Targeting NMNAT1 in Acute Myeloid Leukemia

Xiangguo Shi, PhD, Daisuke Nakada, PhD, Ayumi Kitano, Rebecca Murdaugh, BS, Yu-Jung Tseng, BS,MS, Kevin Hoegenauer, Tianyuan Hu, PhD, Yajian Jiang, BS
Journal: Blood
Blood (2019) 134 (Supplement_1): 879.
https://doi.org/10.1182/blood-2019-132139
Published: 2019
Journal Articles

Adult Hematopoietic Stem and Progenitor Cell Maintenance Requires Histone Variant H3.3 Regulation By Hira

Rebecca Murdaugh, BS, Kevin Hoegenauer, Xiangguo Shi, PhD, Ayumi Kitano, Richard Chapple, PhD, Tianyuan Hu, PhD, Jonathan Tiessen, BS, Daisuke Nakada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2473.
https://doi.org/10.1182/blood-2019-131358
Published: 2019
Journal Articles

An Oncogenic Enhancer Encodes Selective Selenium Dependency in AML

Charles Y Lin, PhD, Joanna S. Yi, MD, Yajian Jiang, MBBS, Daisuke Nakada, PhD, Monika Perez, BS, Jost Koren, M.S., Kenneth Eagle
Journal: Blood
Blood (2019) 134 (Supplement_1): 638.
https://doi.org/10.1182/blood-2019-129433
Published: 2019
Journal Articles

Integrating Enhancer Profiling and CRISPR Dropout Screen Revealed Selenoprotein Synthesis Pathway As a New Vulnerability in AML

Yajian Jiang, MBBS, Xiangguo Shi, PhD, Kenneth Eagle, Charles Y Lin, PhD, Daisuke Nakada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 639.
https://doi.org/10.1182/blood-2019-126904
Published: 2019
Journal Articles

PRDM16s transforms megakaryocyte-erythroid progenitors into myeloid leukemia–initiating cells

Tianyuan Hu, Kiyomi Morita, Matthew C. Hill, Yajian Jiang, Ayumi Kitano, Yusuke Saito, Feng Wang, Xizeng Mao, Kevin A. Hoegenauer, Kazuhiro Morishita, James F. Martin, P. Andrew Futreal, Koichi Takahashi, Daisuke Nakada
Journal: Blood
Blood (2019) 134 (7): 614–625.
https://doi.org/10.1182/blood.2018888255
Published: 2019
Includes: Supplemental data
Journal Articles

ENLightening YEATS in antagonizing polycomb repression

Daisuke Nakada
Journal: Blood
Blood (2018) 131 (6): 591.
https://doi.org/10.1182/blood-2017-12-821553
Published: 2018
Journal Articles

AMPK Links Metabolic Regulation to Epigenome Modification in Leukemia-Initiating-Cell

Yajian Jiang, MBBS, Daisuke Nakada, PhD, Ayumi Kitano
Journal: Blood
Blood (2017) 130 (Supplement 1): 2488.
https://doi.org/10.1182/blood.V130.Suppl_1.2488.2488
Published: 2017
Journal Articles

The Role of Histone Variant H3.3 Regulation By Hira in Hematopoiesis

Rebecca Murdaugh, BS, Kevin Hoegenauer, BS, Richard Chapple, MS, Angelique Lin, MS, Daisuke Nakada, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2415.
https://doi.org/10.1182/blood.V130.Suppl_1.2415.2415
Published: 2017
Journal Articles

AMPK Protects Against Energy Stress and Maintains Histone Acetylation in Leukemia-Initiating-Cell

Yajian Jiang, MBBS, Daisuke Nakada, PhD, Ayumi Kitano, Richard Chapple, MS, Tianyuan Hu, PhD, Angelique Lin, BS
Journal: Blood
Blood (2016) 128 (22): 2701.
https://doi.org/10.1182/blood.V128.22.2701.2701
Published: 2016