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Latasha Little
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Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney D. DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z. Orlowski, Muzaffar H. Qazilbash, Kapil N. Bhalla, Simona Colla, Hagop M. Kantarjian, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Daisuke Nakada, Jeffrey J. Molldrem, Gheath Alatrash, Andrew Futreal, Elizabeth J. Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 346.
https://doi.org/10.1182/blood-2024-208106
Published: 2024
Journal Articles

Lenalidomide promotes the development of TP53 -mutated therapy-related myeloid neoplasms

Clinical Trials & Observations
Adam S. Sperling, Veronica A. Guerra, James A. Kennedy, Yuanqing Yan, Joanne I. Hsu, Feng Wang, Andrew T. Nguyen, Peter G. Miller, Marie E. McConkey, Vanessa A. Quevedo Barrios, Ken Furudate, Linda Zhang, Rashmi Kanagal-Shamanna, Jianhua Zhang, Latasha Little, Curtis Gumbs, Naval Daver, Courtney D. DiNardo, Tapan Kadia, Farhad Ravandi, Hagop Kantarjian, Guillermo Garcia-Manero, P. Andrew Futreal, Benjamin L. Ebert, Koichi Takahashi
Journal: Blood
Blood (2022) 140 (16): 1753–1763.
https://doi.org/10.1182/blood.2021014956
Published: 2022
Includes: Supplemental data
Journal Articles

Clonal dynamics and clinical implications of postremission clonal hematopoiesis in acute myeloid leukemia

Clinical Trials & Observations Brief Report
Tomoyuki Tanaka, Kiyomi Morita, Sanam Loghavi, Feng Wang, Ken Furudate, Yuya Sasaki, Latasha Little, Curtis Gumbs, Jairo Matthews, Naval Daver, Naveen Pemmaraju, Courtney D. DiNardo, Koji Sasaki, Musa Yilmaz, Tapan M. Kadia, Farhad Ravandi, Marina Y. Konopleva, Hagop M. Kantarjian, Richard E. Champlin, Gheath Al-Atrash, Guillermo Garcia-Manero, Sa A. Wang, P. Andrew Futreal, Koichi Takahashi
Journal: Blood
Blood (2021) 138 (18): 1733–1739.
https://doi.org/10.1182/blood.2020010483
Published: 2021
Includes: Supplemental data
Journal Articles

Single-Cell Characterization of Acute Myeloid Leukemia (AML) and Its Microenvironment Identifies Signatures of Resistance to PD-1 Blockade Based Therapy

Hussein A Abbas, MDPhD, Dapeng Hao, Katarzyna Tomczak, PhD, Praveen Barrodia, Jin S. Im, Patrick K Reville, MD, Zoe Alaniz, Wei Wang, MD PhD, Ruiping Wang, PhD, Feng Wang, PhD, Koichi Takahashi, MD PhD, Jing Ning, PhD, Maomao Ding, Jairo A. Matthews, Latasha Little, BS, Jianhua Zhang, PhD, Sreyashi Basu, PhD, Courtney D. DiNardo, MD MSCE, Tapan M. Kadia, MD, Farhad Ravandi, MBBS, Gautam Borthakur, MD, Marina Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Michael R Green, PhD, Gheath Alatrash, Padmanee Sharma, James P Allison, PhD, Steven M. Kornblau, MD, Kunal Rai, Linghua Wang, PhD, P Andrew Futreal, PhD, Naval Daver, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–31.
https://doi.org/10.1182/blood-2020-137335
Published: 2020
Journal Articles

Prognostic Significance of Genetic Alterations in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated with Hyper-CVAD Plus Dasatinib or Hyper-CVAD Plus Ponatinib

Yuya Sasaki, MDPhD, Hagop M. Kantarjian, MD, Nicholas J. Short, MD, Nitin Jain, MD, Koji Sasaki, MD, Farhad Ravandi, MBBS, Marina Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Latasha Little, BS, Curtis Gumbs, Li Zhao, PhD, P Andrew Futreal, PhD, Feng Wang, PhD, Ken Furudate, DDM, PhD, Rebecca Garris, MSc, Koichi Takahashi, MD PhD, Elias Jabbour, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-136676
Published: 2020
Journal Articles

Clonal Dynamics and Clinical Implications of Post-Remission Clonal Hematopoiesis in Acute Myeloid Leukemia (AML)

Tomoyuki Tanaka, Kiyomi Morita, MD, Feng Wang, PhD, Latasha Little, Curtis Gumbs, Jairo Matthews, Courtney D. DiNardo, MDMSc, Tapan M. Kadia, MD, Farhad Ravandi, MD, Marina Y Konopleva, MD PhD, Hagop M. Kantarjian, MD, Richard E. Champlin, MD, Guillermo Garcia-Manero, MD, P Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 17.
https://doi.org/10.1182/blood-2019-122274
Published: 2019
Journal Articles

Prognostic Significance of IKZF1 , PAX5 , and CDKN2A Deletions in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated with Hyper-CVAD/MA with Dasatinib or Ponatinib

Yuya Sasaki, MD PhD, Nicholas J. Short, MD, Hagop M. Kantarjian, MD, Rebecca Garris, MSc, Nitin Jain, MD, Koji Sasaki, MD, Farhad Ravandi, MD, Marina Y Konopleva, MD PhD, Michael E. Rytting, MD, Guillermo Garcia-Manero, MD, Latasha Little, BS, Curtis Gumbs, Li Zhao, PhD, P. Andrew Futreal, PhD, Feng Wang, PhD, Koichi Takahashi, MD, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2753.
https://doi.org/10.1182/blood-2019-122017
Published: 2019
Journal Articles

Comprehensive Analysis of Genotype and Prior Exposures in Therapy-Related Myeloid Neoplasms (t-MNs)

Veronica A Guerra, MD, Yan Yuanqing, PhD, Joanne Hsu, BS, Feng Wang, PhD, Mansour Alfayez, MD, Kiyomi Morita, MD, Xingzhi Song, PhD, Courtney D. DiNardo, MD MSc, Marina Y Konopleva, MD PhD, Gautam M. Borthakur, MD, Guillermo Montalban Bravo, MD, Jianhua Zhang, PhD, Latasha Little, BS, Curtis Gumbs, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 458.
https://doi.org/10.1182/blood-2019-127498
Published: 2019
Journal Articles

Characterization of Changes in the T-Cell Receptor Repertoire in Patients with Acute Myeloid Leukemia with Durable Remission Following Allogeneic Stem Cell Transplant

Ronald M. Paranal, MD, Hagop M. Kantarjian, MD, Alexandre Reuben, PhD, Celine Kerros, PhD, Priya Koppikar, PhD, Latasha Little, BS, Curtis Gumbs, Nicholas J. Short, MD, Jorge E. Cortes, MD, Elias Jabbour, MD, Jeffrey J. Molldrem, P. Andrew Futreal, PhD, Ghayas C. Issa, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5186.
https://doi.org/10.1182/blood-2019-129911
Published: 2019
Journal Articles

Pan-Myeloid Leukemia Analysis: Machine Learning-Based Approach to Predict Phenotype and Clinical Outcomes Using Mutation Data

Kiyomi Morita, MD, Feng Wang, PhD, Hideki Makishima, MD PhD, Yuanqing Yan, PhD, Tetsuichi Yoshizato, MD PhD, Kenichi Yoshida, MD PhD, Bartlomiej P. Przychodzen, Keyur Patel, MD PhD, Carlos E. Bueso-Ramos, MD PhD, Curtis Gumbs, Latasha Little, Samantha Tippen, Jianhua Zhang, PhD, Xingzhi Song, PhD, Tapan M. Kadia, MD, Naval G. Daver, MD, Naveen Pemmaraju, MD, Courtney D. DiNardo, MDMSc, Farhad Ravandi, MD, Srdan Verstovsek, MD PhD, Elias J. Jabbour, MD, Jorge E. Cortes, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, Jaroslaw P. Maciejewski, Seishi Ogawa, MD PhD, P Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1801.
https://doi.org/10.1182/blood-2018-99-116685
Published: 2018
Journal Articles

Single-Cell Atlas of Driver Mutations in Acute Myeloid Leukemia (AML)

Kiyomi Morita, MD, Feng Wang, PhD, Robert Durruthy-Durruthy, PhD, Anup Parikh, Jairo Matthews, BA, Latasha Little, Samantha Tippen, Curtis Gumbs, Jianhua Zhang, PhD, Xingzhi Song, PhD, Erika Thompson, MS, Keyur Patel, MD PhD, Carlos E. Bueso-Ramos, MD PhD, Courtney D. DiNardo, MDMSc, Farhad Ravandi, MD, Elias J. Jabbour, MD, Michael Andreeff, MD PhD, Jorge E. Cortes, MD, Marina Y. Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Dennis J. Eastburn, PhD, P Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 88.
https://doi.org/10.1182/blood-2018-99-117358
Published: 2018
Journal Articles

Clinical Heterogeneity of AML Is Associated with Mutational Heterogeneity

Mahesh Swaminathan, MD, Kiyomi Morita, MD, Yan Yuanqing, Feng Wang, PhD, Jared K Burks, PhD, Curtis Gumbs, Latasha Little, Samantha Tippen, Rebecca Thornton, Marcus Coyle, Jianhua Zhang, PhD, Xingzhi Song, PhD, Courtney D. DiNardo, MD MSc, Elias J. Jabbour, MD, Tapan M. Kadia, MD, Jorge E. Cortes, MD, Naval G. Daver, MD, Naveen Pemmaraju, MD, Keyur Patel, MD PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Carlos E. Bueso-Ramos, MD PhD, Andy Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5240.
https://doi.org/10.1182/blood-2018-99-117287
Published: 2018
Journal Articles

Comprehensive Genomic Analysis of IDH Inhibitor-Treated AML Samples Delineates Molecular Mechanisms of Differentiation and Heterogeneous Patterns of Acquired Resistance

Feng Wang, PhD, Kiyomi Morita, MD, Courtney D. DiNardo, MDMSc, Keyur Patel, MD PhD, Kyle MacBeth, PhD, Alessandra Tosolini, BS, Mark G. Frattini, MD, Jairo Matthews, BA, Latasha Little, Curtis Gumbs, Samantha Tippen, Xingzhi Song, PhD, Jianhua Zhang, PhD, Erika Thompson, MS, Tapan M. Kadia, MD, Guillermo Garcia-Manero, MD, Elias J. Jabbour, MD, Farhad Ravandi, MD, Marina Y. Konopleva, MD PhD, Hagop M. Kantarjian, MD, Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 441.
https://doi.org/10.1182/blood-2018-99-116383
Published: 2018
Journal Articles

Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

Clinical Trials & Observations
Koichi Takahashi, Boyu Hu, Feng Wang, Yuanqing Yan, Ekaterina Kim, Candida Vitale, Keyur P. Patel, Paolo Strati, Curtis Gumbs, Latasha Little, Samantha Tippen, Xingzhi Song, Jianhua Zhang, Nitin Jain, Philip Thompson, Guillermo Garcia-Manero, Hagop Kantarjian, Zeev Estrov, Kim-Anh Do, Michael Keating, Jan A. Burger, William G. Wierda, P. Andrew Futreal, Alessandra Ferrajoli
Journal: Blood
Blood (2018) 131 (16): 1820–1832.
https://doi.org/10.1182/blood-2017-11-817296
Published: 2018
Includes: Supplemental data
Journal Articles

Persistent Somatic Mutation at Remission Is Associated with Poor Survival and Higher Risk of Relapse in Patients with Acute Myeloid Leukemia

Kiyomi Morita, MD, Feng Wang, PhD, Keyur Patel, MD PhD, Carlos Bueso-Ramos, MD PhD, Ghayas C. Issa, MD, Xingzhi Song, Jianhua Zhang, Samantha Tippen, Rebecca Thornton, Marcus Coyle, Latasha Little, Curtis Gumbs, Farhad Ravandi, MBBS, Tapan Kadia, MD, Naval Daver, MD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Jorge E. Cortes, MD, Guillermo Garcia-Manero, MD, Elias J. Jabbour, MD, Andrew Futreal, PhD, Hagop M. Kantarjian, MD, Koichi Takahashi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2667.
https://doi.org/10.1182/blood.V130.Suppl_1.2667.2667
Published: 2017