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Journal Articles

Characterization of Dysregulated Transcription in TP53 -Mutated AML Subpopulations

Ghayas C. Issa, Vakul Mohanty, Edward Ayoub, Feng Wang, Jake Leighton, Xiaogang Wu, Aram Bidikian, Tallie Patsilevas, Zoe Alaniz, Jabra Zarka, Rashmi Kanagal-Shamanna, Andy Futreal, Naval Daver, Marina Konopleva, Nicholas Navin, Jianhua Zhang, Ken Chen, Michael Andreeff
Journal: Blood
Blood (2022) 140 (Supplement 1): 6323–6325.
https://doi.org/10.1182/blood-2022-168136
Published: 2022
Journal Articles

Somatic Mutations in TP53 Identified in T-Cells of Patients with TP53- mutated AML

Ghayas C. Issa, Aram Bidikian, Edward Ayoub, Feng Wang, Vakul Mohanty, Jake Leighton, Xiaogang Wu, Tallie Patsilevas, Zoe Alaniz, Jabra Zarka, Rashmi Kanagal-Shamanna, Naval Daver, Andy Futreal, Marina Konopleva, Nicholas Navin, Jianhua Zhang, Ken Chen, Michael Andreeff
Journal: Blood
Blood (2022) 140 (Supplement 1): 6267–6269.
https://doi.org/10.1182/blood-2022-165439
Published: 2022
Journal Articles

Targeting EZH1/2 to Restore Chemosensitivity in Dormant Myeloid Leukemia Stem Cells

Kyung Hee Chang, Mahesh Basyal, Zoe Alaniz, Daisuke Honma, Shinji Tsutsumi, Cedric E. Dos Santos, Naval Daver, Michael Andreeff
Journal: Blood
Blood (2021) 138 (Supplement 1): 2943.
https://doi.org/10.1182/blood-2021-152884
Published: 2021
Journal Articles

Venetoclax enhances T cell–mediated antileukemic activity by increasing ROS production

Jong Bok Lee, Dilshad H. Khan, Rose Hurren, Mingjing Xu, Yoosu Na, Hyeonjeong Kang, Sara Mirali, Xiaoming Wang, Marcela Gronda, Yulia Jitkova, Neil MacLean, Andrea Arruda, Zoe Alaniz, Marina Y. Konopleva, Michael Andreeff, Mark D. Minden, Li Zhang, Aaron D. Schimmer
Journal: Blood
Blood (2021) 138 (3): 234–245.
https://doi.org/10.1182/blood.2020009081
Published: 2021
Includes: Supplemental data
Journal Articles

High-Dimensional Single-Cell Proteomic Analysis Reveals Therapeutic Vulnerabilities in Relapsed/Refractory AML By Concomitant Analysis of Cell Surface Antigens, Signaling Pathways and Anti-Apoptotic Proteins

Muharrem Muftuoglu, MD, Zoe Alaniz, BS, Duncan Mak, BSc, MPhil, Angelique J. Lin, MS, Jared K. Burks, PhD, Bing Z Carter, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26.
https://doi.org/10.1182/blood-2020-143432
Published: 2020
Journal Articles

Mdm2 Loss of Heterozygosity Cooperates with Mutant p53 in Acute Myeloid Leukemia

Rasoul Pourebrahim, MDPhD, Rafael Heinz Montoya, BS, Zoe Alaniz, Lauren B Ostermann, BS, Hung Alex Luong, Joseph D. Khoury, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-142523
Published: 2020
Journal Articles

Osterix Marks a Distinct Population of Circulatory Bone Marrow Mesenchymal Stem Cells That Is Increased upon Oncogenic Stress

Rafael Heinz Montoya, BS, Rasoul Pourebrahim, Zoe Alaniz, BS, Lauren B Ostermann, BS, Jared K. Burks, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-142713
Published: 2020
Journal Articles

Inhibition of EZH1 and EZH2 Restores Chemosensitivity of Leukemia Stem Cells in Acute Myeloid Leukemia By Recruitment of Quiescent AML Stem/Progenitor Cells

Kyung Hee Chang, PhD, Zoe Alaniz, Yuki Nishida, MDPhD, Cedric E. Dos Santos, PhD, Eric Slosberg, PhD, Naval Daver, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-142071
Published: 2020
Journal Articles

Single-Cell Characterization of Acute Myeloid Leukemia (AML) and Its Microenvironment Identifies Signatures of Resistance to PD-1 Blockade Based Therapy

Hussein A Abbas, MDPhD, Dapeng Hao, Katarzyna Tomczak, PhD, Praveen Barrodia, Jin S. Im, Patrick K Reville, MD, Zoe Alaniz, Wei Wang, MD PhD, Ruiping Wang, PhD, Feng Wang, PhD, Koichi Takahashi, MD PhD, Jing Ning, PhD, Maomao Ding, Jairo A. Matthews, Latasha Little, BS, Jianhua Zhang, PhD, Sreyashi Basu, PhD, Courtney D. DiNardo, MD MSCE, Tapan M. Kadia, MD, Farhad Ravandi, MBBS, Gautam Borthakur, MD, Marina Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Michael R Green, PhD, Gheath Alatrash, Padmanee Sharma, James P Allison, PhD, Steven M. Kornblau, MD, Kunal Rai, Linghua Wang, PhD, P Andrew Futreal, PhD, Naval Daver, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–31.
https://doi.org/10.1182/blood-2020-137335
Published: 2020
Journal Articles

Mdm2 Haplo-Insufficiency in Hematopoietic and Mesenchymal Progenitor Cells Results in Cell Death

Rasoul Pourebrahim, MDPhD, Rafael Heinz Montoya, BS, Zoe Alaniz, BS, Lauren B Ostermann, BS, Edward Ayoub, PhD MS, BSc, Patrick P Lin, MD, Jared K. Burks, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-142662
Published: 2020
Journal Articles

p53 Mediated Bone Marrow Mesenchymal Stem Cell Expansion Supports Acute Myeloid Leukemia Development

Rasoul Pourebrahimabadi, MD PhD, Zoe Alaniz, Lauren B Ostermann, Hung Alex Luong, Rafael Heinz Montoya, Peter P. Ruvolo, PhD, Steven M. Kornblau, MD, Joseph D. Khoury, MD, Carlos E. Bueso-Ramos, MD PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 523.
https://doi.org/10.1182/blood-2019-127245
Published: 2019
Journal Articles

Identification of Gene Expression Signatures in Leukemia Stem Cells and Minimal Residual Disease Following Treatment of Adverse Risk Acute Myeloid Leukemia

Ghayas C. Issa, MD, Christopher B. Benton, MD, Vakul Mohanty, PhD, Yifei Shen, PhD, Zoe Alaniz, Feng Wang, PhD, P. Andrew Futreal, PhD, Wei Wang, MD PhD, Jeffrey L. Jorgensen, MD PhD, Nicholas Navin, PhD, Marina Y Konopleva, MD PhD, Ken Chen, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2717.
https://doi.org/10.1182/blood-2019-130540
Published: 2019
Journal Articles

Distinct Gene Expression Patterns of Minimal Residual Disease (MRD) Cells in High-Risk AML Patients Identified By RNA-Sequencing

Christopher B. Benton, MD, Ahmed Al Rawi, Feng Wang, PhD, Jianhua Zhang, PhD, Jeffrey L. Jorgensen, MD PhD, Hong Mu, MD PhD, Wendy Schober, Zoe Alaniz, Curtis Gumbs, Andy Futreal, PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Nicholas Navin, PhD, Marina Y. Konopleva, MD PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2757.
https://doi.org/10.1182/blood-2018-99-120260
Published: 2018