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Journal Articles

Novel p53 Mutant Mouse Model Recapitulates the Biology of Human Therapy-Related Myeloid Neoplasms

Rasoul Pourebrahim, Dexin Yang, Priyanka Khanna, Muharrem Muftuoglu, Lauren B. Ostermann, Shayaun Khazaei, Ran Zhao, Mihai Gagea, Simona Colla, Guillermo Garcia-Manero, Ruoyan Li, Michael Andreeff, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 882.
https://doi.org/10.1182/blood-2024-207582
Published: 2024
Journal Articles

Mitigating Therapy-Related Myeloid Neoplasia in p53-Mutant Clones through Targeted DNA Repair Pathway Inhibition with PARP Inhibitors

Rasoul Pourebrahim, Priyanka Khanna, Dexin Yang, Muharrem Muftuoglu, Lauren B. Ostermann, Shayaun Khazaei, Ran Zhao, Amma Asare, Richard A. Hajek, Sanghoon Lee, Sara Corvingo, Mihai Gagea, Anil Sood, Ruoyan Li, Koichi Takahashi, Michael Andreeff
Journal: Blood
Blood (2024) 144 (Supplement 1): 726.
https://doi.org/10.1182/blood-2024-208373
Published: 2024
Journal Articles

Age-Specific Induction of Mutant p53 Drives Clonal Hematopoiesis in Adult Mice Leading to Acute Myeloid Leukemia

Rasoul Pourebrahim, Shayaun Khazaei, Lauren B. Ostermann, Ran Zhao, Muharrem Muftuoglu, Michael Andreeff
Journal: Blood
Blood (2023) 142 (Supplement 1): 1382.
https://doi.org/10.1182/blood-2023-186454
Published: 2023
Journal Articles

Mdm2 Loss of Heterozygosity Cooperates with Mutant p53 in the Development of Acute Myeloid Leukemia

Rasoul Pourebrahim, Rafael Heinz Montoya, Edward Ayoub, Hiroki Akiyama, Natalia Baran, Tom Lesluyes, Lauren B Ostermann, Bin Liu, Jo Ishizawa, Joseph D. Khoury, Marina Konopleva, Peter Van Loo, Michael Andreeff
Journal: Blood
Blood (2022) 140 (Supplement 1): 5876–5878.
https://doi.org/10.1182/blood-2022-167859
Published: 2022
Journal Articles

Traceable Mouse Models for Tracking p53-Mutant Subclones in Acute Myeloid Leukemia

Rasoul Pourebrahim, Rafael Heinz Montoya, Lauren B Ostermann, Michael Andreeff
Journal: Blood
Blood (2022) 140 (Supplement 1): 2964–2965.
https://doi.org/10.1182/blood-2022-167905
Published: 2022
Journal Articles

Mdm2 Maintains Cholesterol Biosynthesis in Hematopoietic Stem/Progenitor Cells Independent of p53

Rasoul Pourebrahim, Rafael Heinz Montoya, Edward Ayoub, Joseph D. Khoury, Michael Andreeff
Journal: Blood
Blood (2021) 138 (Supplement 1): 1152.
https://doi.org/10.1182/blood-2021-152899
Published: 2021
Journal Articles

Mdm2 Loss of Heterozygosity Cooperates with Mutant p53 in Acute Myeloid Leukemia

Rasoul Pourebrahim, MDPhD, Rafael Heinz Montoya, BS, Zoe Alaniz, Lauren B Ostermann, BS, Hung Alex Luong, Joseph D. Khoury, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-142523
Published: 2020
Journal Articles

Osterix Marks a Distinct Population of Circulatory Bone Marrow Mesenchymal Stem Cells That Is Increased upon Oncogenic Stress

Rafael Heinz Montoya, BS, Rasoul Pourebrahim, Zoe Alaniz, BS, Lauren B Ostermann, BS, Jared K. Burks, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-142713
Published: 2020
Journal Articles

Mdm2 Haplo-Insufficiency in Hematopoietic and Mesenchymal Progenitor Cells Results in Cell Death

Rasoul Pourebrahim, MDPhD, Rafael Heinz Montoya, BS, Zoe Alaniz, BS, Lauren B Ostermann, BS, Edward Ayoub, PhD MS, BSc, Patrick P Lin, MD, Jared K. Burks, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-142662
Published: 2020
Journal Articles

Genetic Dissection of p53 Driven Senescence of Bone Marrow Mesenchymal Cells in Acute Myeloid Leukemia

Rasoul Pourebrahim, MD PhD, Peter P. Ruvolo, PhD, Steven M. Kornblau, MD, Carlos E. Bueso-Ramos, MD PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2625.
https://doi.org/10.1182/blood-2018-99-117585
Published: 2018