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Journal Articles

Novel Transcriptomics Based Stratification Approach Using the Commpass Dataset Reveals Mechanistic Insights into Current and Upcoming MM Therapies

Habib Hamidi, Teiko Sumiyoshi, Cedric E. Dos Santos, Samuel Tracy, Hearn J. Cho, Stephanie Hilz, Vivek S. Chopra
Journal: Blood
Blood (2022) 140 (Supplement 1): 7208–7210.
https://doi.org/10.1182/blood-2022-163868
Published: 2022
Journal Articles

The Pre-Existing T Cell Landscape Is Associated with Response to High Dose Melphalan and Autologous Stem Cell Transplant in Multiple Myeloma

Mohammad Issam Abu Zaid, Parvathi Sudha, Travis S Johnson, Vivek S. Chopra, Cedric E. Dos Santos, Michael Nixon, Attaya Suvannasankha, Sherif S Farag, Kelvin P. Lee, Rafat Abonour, Brian A. Walker
Journal: Blood
Blood (2022) 140 (Supplement 1): 9919–9920.
https://doi.org/10.1182/blood-2022-167619
Published: 2022
Journal Articles

Single Cell Multiomic Analysis Reveals Relapsed and Refractory Multiple Myeloma Cells Associated with 1q, TP53 , and PHF19 alterations That Affect Subclonal Chromatin Accessibility

Travis S Johnson, Parvathi Sudha, Enze Liu, Vivek S. Chopra, Cedric E. Dos Santos, Michael Nixon, Kun Huang, Rafat Abonour, Mohammad Issam Abu Zaid, Brian A. Walker
Journal: Blood
Blood (2022) 140 (Supplement 1): 598–599.
https://doi.org/10.1182/blood-2022-167301
Published: 2022
Journal Articles

Targeting EZH1/2 to Restore Chemosensitivity in Dormant Myeloid Leukemia Stem Cells

Kyung Hee Chang, Mahesh Basyal, Zoe Alaniz, Daisuke Honma, Shinji Tsutsumi, Cedric E. Dos Santos, Naval Daver, Michael Andreeff
Journal: Blood
Blood (2021) 138 (Supplement 1): 2943.
https://doi.org/10.1182/blood-2021-152884
Published: 2021
Journal Articles

Inhibition of EZH1 and EZH2 Restores Chemosensitivity of Leukemia Stem Cells in Acute Myeloid Leukemia By Recruitment of Quiescent AML Stem/Progenitor Cells

Kyung Hee Chang, PhD, Zoe Alaniz, Yuki Nishida, MDPhD, Cedric E. Dos Santos, PhD, Eric Slosberg, PhD, Naval Daver, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-142071
Published: 2020
Journal Articles

Clonal Expansion of Mutant p53 Clones By MDM2 Inhibition in Acute Myeloid Leukemias

Yuki Nishida, MDPhD, Rafael Heinz Montoya, BS, Kiyomi Morita, MDPhD, Tomoyuki Tanaka, MDPhD, Feng Wang, PhD, Koichi Takahashi, MD PhD, Jo Ishizawa, MDPhD, Prasanna Kumar, PhD, Parul Patel, PhD, Cedric E. Dos Santos, PhD, Courtney D. DiNardo, MD MSCE, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-142794
Published: 2020
Journal Articles

Effect of Co-Mutations and FLT3 -ITD Variant Allele Frequency (VAF) on Response to Quizartinib or Salvage Chemotherapy (SC) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Alexander E. Perl, MD, Jorge E. Cortes, MD, Siddhartha Ganguly, MD, Samer K. Khaled, MD, Alwin Krämer, MD, Giovanni Martinelli, MD, Nigel H. Russell, MD, Ken CN Chang, PhD, Derek E. Mires, PharmD, Kazunobu Kato, MD PhD, Yufen Zhang, PhD, Sergey Korkhov, Zhenyu Wang, PhD, Tobias Günnel, PhD, Hiroyuki Sumi, PhD, Takeshi Isoyama, PhD, Arnaud Lesegretain, Flora Berisha, MS, Cedric E. Dos Santos, PhD, Mark J. Levis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 737.
https://doi.org/10.1182/blood-2019-121880
Published: 2019
Journal Articles

IDO Pathway Analysis for Identifying Novel Biomarkers in Multiple Myeloma

Vladimir Petrovic, PhD, Jamie Wong, Cedric E. Dos Santos, PhD, Richard Smith, Dan Fitzpatrick, Robert Loberg, Ariel Avilion, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5572.
https://doi.org/10.1182/blood-2018-99-111392
Published: 2018
Journal Articles

Utilization of Metabolomics to Identify Biomarkers in Hematological Malignancies: Role of IDO and the Tryptophan Pathway

Elizabeth Finger, Jamie Wong, Julia Gray, Dan Rock, Robert Loberg, Dan Fitzpatrick, Richard Smith, Xiaozhen Wang, Cedric E. Dos Santos
Journal: Blood
Blood (2017) 130 (Supplement 1): 5100.
https://doi.org/10.1182/blood.V130.Suppl_1.5100.5100
Published: 2017
Journal Articles

Baseline Biomarkers Influencing Clinical Outcomes in Adults with Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia (R/R ALL) Treated with Blinatumomab Versus Standard-of-Care Chemotherapy (SOC) from a Randomized Phase 3 Study

Andrew Wei, MBBS, PhD FRACP, FRCPA, Josep-Maria Ribera, MD, Giovanni Martinelli, Richard A. Larson, MD, David Ritchie, MD PhD, Armin Ghobadi, MD, Yuqi Chen, Cedric E. Dos Santos, Zachary F. Zimmerman, MD PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2556.
https://doi.org/10.1182/blood.V130.Suppl_1.2556.2556
Published: 2017
Journal Articles

Peripheral Blood As a Substitute for Bone Marrow for Assessing the Immune Profile in AML

Robin Lesley, PhD, Karl Beutner, Abraham A Anderson, Dan Fitzpatrick, Robert Loberg, Bhakti Mehta, Cedric E. Dos Santos
Journal: Blood
Blood (2017) 130 (Supplement 1): 3924.
https://doi.org/10.1182/blood.V130.Suppl_1.3924.3924
Published: 2017
Journal Articles

CD33/CD3-Bispecific T-Cell Engaging (BiTE®) Antibody Constructs Efficiently Target Monocytic CD14 + hla-DR low IDO + aml-MDSCs

Dimitrios Mougiakakos, Domenica Saul, Martina Braun, Dr., Sehmus Tohumeken, Roman Kischel, MD, Lutteropp Michael, Dr., Cedric E. Dos Santos, Regina Jitschin, PhDMD, Andreas Mackensen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1363.
https://doi.org/10.1182/blood.V130.Suppl_1.1363.1363
Published: 2017