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Courtney D. DiNardo
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Journal Articles

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

Fernanda Gutierrez-Rodrigues, Emma M. Groarke, Natthakan Thongon, Juan Jose Rodriguez-Sevilla, Luiz Fernando B. Catto, Marena R. Niewisch, Ruba Shalhoub, Lisa J. McReynolds, Diego V. Clé, Bhavisha A. Patel, Xiaoyang Ma, Dalton Hironaka, Flávia S. Donaires, Nina Spitofsky, Barbara A. Santana, Tsung-Po Lai, Lemlem Alemu, Sachiko Kajigaya, Ivana Darden, Weiyin Zhou, Paul V. Browne, Subrata Paul, Justin Lack, David J. Young, Courtney D. DiNardo, Abraham Aviv, Feiyang Ma, Michel Michels De Oliveira, Ana Paula de Azambuja, Cynthia E. Dunbar, Malgorzata Olszewska, Emmanuel Olivier, Eirini P. Papapetrou, Neelam Giri, Blanche P. Alter, Carmem Bonfim, Colin O. Wu, Guillermo Garcia-Manero, Sharon A. Savage, Neal S. Young, Simona Colla, Rodrigo T. Calado
Journal: Blood
Blood (2024) 144 (23): 2402–2416.
https://doi.org/10.1182/blood.2024025023
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic risk classification for adults with AML receiving less-intensive therapies: the 2024 ELN recommendations

Hartmut Döhner, Courtney D. DiNardo, Frederick R. Appelbaum, Charles Craddock, Hervé Dombret, Benjamin L. Ebert, Pierre Fenaux, Lucy A. Godley, Robert P. Hasserjian, Richard A. Larson, Ross L. Levine, Yasushi Miyazaki, Dietger Niederwieser, Gert Ossenkoppele, Christoph Röllig, Jorge Sierra, Eytan M. Stein, Martin S. Tallman, Hwei-Fang Tien, Jianxiang Wang, Agnieszka Wierzbowska, Andrew H. Wei, Bob Löwenberg
Journal: Blood
Blood (2024) 144 (21): 2169–2173.
https://doi.org/10.1182/blood.2024025409
Published: 2024
Journal Articles

Genetic risk stratification and outcomes among treatment-naive patients with AML treated with venetoclax and azacitidine

CME Clinical Trials & Observations
Hartmut Döhner, Keith W. Pratz, Courtney D. DiNardo, Andrew H. Wei, Brian A. Jonas, Vinod A. Pullarkat, Michael J. Thirman, Christian Récher, Andre C. Schuh, Sunil Babu, Xiaotong Li, Grace Ku, Zihuan Liu, Yan Sun, Jalaja Potluri, Monique Dail, Brenda Chyla, Daniel A. Pollyea
Journal: Blood
Blood (2024) 144 (21): 2211–2222.
https://doi.org/10.1182/blood.2024024944
Published: 2024
Includes: Supplemental data
Journal Articles

Preclinical efficacy of CDK7 inhibitor-based combinations against myeloproliferative neoplasms transformed to AML

Warren Fiskus, Christopher P Mill, Prithviraj Bose, Lucia Masarova, Naveen Pemmaraju, Andrew Dunbar, Christine Birdwell, John A Davis, Kaberi Das, Hanxi Hou, Taghi Manshouri, Antrix Jain, Anna Malovannaya, Kevin Philip, Noor Alhamadani, Alicia Matthews, Katie Lin, Lauren Flores, Sanam Loghavi, Courtney D. DiNardo, Xiaoping Su, Raajit K. Rampal, Kapil N Bhalla
Journal: Blood
Blood blood.2024026388.
https://doi.org/10.1182/blood.2024026388
Published: 2024
Includes: Supplemental data
Journal Articles

IO-202, a Novel Anti-LILRB4 Antibody, with Azacitidine for Hypomethylating Agent-Naive Chronic Myelomonocytic Leukemia: Phase 1b Expansion Cohort Results

Gabriel N Mannis, Ahmed Aribi, Neil Dunavin, Hetty E. Carraway, Jennifer N. Saultz, Gail J. Roboz, Brian A. Jonas, Yazan F Madanat, Guillermo Garcia-Manero, Deepa Jeyakumar, Daniel A Pollyea, Olatoyosi Odenike, William Blum, Gary J. Schiller, Yasuhiro Tabata, Donna Valencia, Tao Huang, Wen Hong Lin, Hong Xiang, Charlene Liao, Courtney D. DiNardo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1008.
https://doi.org/10.1182/blood-2024-206538
Published: 2024
Journal Articles

Updated Results from a Phase II Study of Vibecotamab, a CD3-CD123 Bispecific T-Cell Engaging Antibody, for MDS or CMML after Hypomethylating Failure and in MRD-Positive AML

Daniel Nguyen, Farhad Ravandi, Sa A. Wang, Jeffrey L. Jorgensen, Wei WANG, Sanam Loghavi, Jaehyun Lee, Pavan Bachireddy, Courtney D. DiNardo, Kelly S. Chien, Guillermo Montalban-Bravo, Ghayas C. Issa, Abhishek Maiti, Yesid Alvarado Valero, Naval Daver, Elias Jabbour, Tapan M. Kadia, Naveen Pemmaraju, Musa Yilmaz, Danielle T Nguyen, Uday Popat, Elizabeth J. Shpall, Guillermo Garcia-Manero, Hagop Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 1007.
https://doi.org/10.1182/blood-2024-208684
Published: 2024
Journal Articles

Clonal Basis of Resistance and Response to Ivosidenib Combination Therapies Is Established Early during Treatment in IDH1 -Mutated Myeloid Malignancies

Sven Turkalj, Bilyana Stoilova, Angus J Groom, Felix A Radtke, Rabea Mecklenbrauck, Niels Asger Jakobsen, Curtis A Lachowiez, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Zhihong Zeng, Sanam Loghavi, Jennifer Marvin-Peek, Verena Körber, Farhad Ravandi, Ghayas C. Issa, Tapan M. Kadia, Vasiliki Symeonidou, Anne De Groot, Hagop M. Kantarjian, Koichi Takahashi, Marina Konopleva, Courtney D. DiNardo, Paresh Vyas
Journal: Blood
Blood (2024) 144 (Supplement 1): 642.
https://doi.org/10.1182/blood-2024-201970
Published: 2024
Journal Articles

Safety and Efficacy of G-CSF with Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia: A Subgroup Analysis of the Phase II Trial of Venetoclax in Combination with Cladribine, Idarubicin, and Cytarabine

Ian M. Bouligny, Hagop M. Kantarjian, Musa Yilmaz, Naval Daver, Gautam Borthakur, Courtney D. DiNardo, Guillermo Montalban-Bravo, Nicholas J. Short, Yesid Alvarado Valero, Nitin Jain, Naveen Pemmaraju, Danielle Hammond, Kelly S. Chien, Koichi Takahashi, Ghayas C. Issa, Hussein A. Abbas, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 446.
https://doi.org/10.1182/blood-2024-203938
Published: 2024
Journal Articles

Impact of Flow Cytometry-Based Measurable Residual Disease Clearance Kinetics in Patients with Acute Myeloid Leukemia Undergoing Intensive Chemotherapy

Wei-Ying Jen, Koji Sasaki, Farhad Ravandi, Tapan M. Kadia, Sa A. Wang, Wei Wang, Sanam Loghavi, Naval Daver, Courtney D. DiNardo, Ghayas C. Issa, Hussein A. Abbas, Cedric Nasnas, Alex Bataller, Samuel Urrutia, Sherry Pierce, Hagop M. Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 1572.
https://doi.org/10.1182/blood-2024-212036
Published: 2024
Journal Articles

Impact of Post-Remission Intensive (IC) Consolidation Chemotherapy Cycles on Overall and Relapse Free Survival after Allogeneic Stem Cell Transplant (SCT) in Patients with Acute Myeloid Leukemia (AML) Receiving IC + Venetoclax

Jennifer Marvin-Peek, Hagop M. Kantarjian, Wei-Ying Jen, Gautam Borthakur, Naval Daver, Abhishek Maiti, Nicholas J. Short, Steven M. Kornblau, Naveen Pemmaraju, Eitan Kugler, Alexandre Bazinet, Yesid Alvarado-Valero, Hussein A. Abbas, Guillermo Garcia-Manero, Uday Popat, Elizabeth J. Shpall, Farhad Ravandi, Courtney D. DiNardo, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 3572.
https://doi.org/10.1182/blood-2024-202414
Published: 2024
Journal Articles

Causes of Death in Patients with Myelodysplastic Syndrome and Spliceosome Mutations

Arjun S. Peddireddy, Panayiotis Kontoyiannis, Koji Sasaki, Kelly S. Chien, Jayastu Senapati, Guillermo Montalban-Bravo, Courtney D. DiNardo, Gautam Borthakur, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Sherry Pierce, Hagop M. Kantarjian, Guillermo Garcia-Manero, Samuel Urrutia
Journal: Blood
Blood (2024) 144 (Supplement 1): 6704.
https://doi.org/10.1182/blood-2024-202540
Published: 2024
Journal Articles

Phase 1b/2 Study of Decitabine and Venetoclax in Combination with the Targeted Mutant IDH1 Inhibitor Olutasidenib for Patients with Relapsed/Refractory AML, High Risk MDS, or Newly Diagnosed AML Not Eligible for Chemotherapy with an IDH1 Mutation

Courtney D. DiNardo, Kelly S. Chien, Jillian Mullin, Danielle Hammond, Jeremy Ramdial, Tapan M. Kadia, Fadi G. Haddad, Musa Yilmaz, Koji Sasaki, Ghayas C. Issa, Koichi Takahashi, Elizabeth J. Shpall, Farhad Ravandi, Naval Daver, Hagop Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 1527.2.
https://doi.org/10.1182/blood-2024-208771
Published: 2024
Journal Articles

A Phase I/II Study of Gilteritinib and Momelotinib for Patients with Relapsed/Refractory FLT3 -Mutated Acute Myeloid Leukemia: A Trial in Progress

Nicholas J. Short, Farhad Ravandi, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Tapan M. Kadia, Musa Yilmaz, Ghayas C. Issa, Regina Abramova, Araceli Isabella Garza, Hagop M. Kantarjian, Hussein A. Abbas
Journal: Blood
Blood (2024) 144 (Supplement 1): 4288.1.
https://doi.org/10.1182/blood-2024-200923
Published: 2024
Journal Articles

Ivosidenib in Patients with Mutant Isocitrate Dehydrogenase 1 (m IDH1 ) Relapsed/Refractory Myelodysplastic Syndromes: Update of the Phase 1 Substudy per the International Working Group 2023 Response Criteria

Yazan F Madanat, Amir T. Fathi, Guillermo Garcia-Manero, Gail J. Roboz, Justin M. Watts, Gabrielle T. Prince, Praneeth Baratam, Stephane De Botton, Anthony S. Stein, James M. Foran, Martha L. Arellano, David Sallman, Yuanye (Vickie) Zhang, Stephanie M. Kapsalis, Prapti A. Patel, Courtney D. DiNardo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1841.
https://doi.org/10.1182/blood-2024-204862
Published: 2024
Journal Articles

A Phase I Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with High Risk or Refractory/Relapsed Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Gheath Alatrash, Cristina Knape, Laura Whited, Dawen Sui, Cara L Haymaker, Jason Yeh, Megan Marcotulli, Pariya Sukhumalchandra, Lisa St. John, Hsinyi Lu, Daniela E. Duenas, Ignacio Wistuba, Julia Mendoza Perez, Beatriz Sanchez Espiridion, Roland L. Bassett, Tapan M. Kadia, Courtney D. DiNardo, Farhad Ravandi, Jeremy Ramdial, Rohtesh S. Mehta, Amin M. Alousi, Betul Oran, Issa F. Khouri, Qaiser Bashir, Chitra Hosing, Muzaffar H. Qazilbash, Jin S. Im, Partow Kebriaei, Pavan Bachireddy, Jeffrey J. Molldrem, Jeffrey L. Jorgensen, Sa A. Wang, Wei WANG, Uday Popat, Elizabeth J. Shpall, Richard E. Champlin, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 1047.
https://doi.org/10.1182/blood-2024-211343
Published: 2024
Journal Articles

A Phase II Trial of Azacitidine with Ipilimumab, Nivolumab, or Ipilimumab and Nivolumab in Previously Untreated Myelodysplastic Syndrome

Ian M. Bouligny, Guillermo Montalban-Bravo, Koji Sasaki, Naval Daver, Elias Jabbour, Yesid Alvarado Valero, Courtney D. DiNardo, Farhad Ravandi, Gautam Borthakur, Prithviraj Bose, Naveen Pemmaraju, Steven M. Kornblau, Tapan M. Kadia, Lucia Masarova, Koichi Takahashi, Michael Andreeff, Alexandre Bazinet, Hui Yang, Rashmi Kanagal-Shamanna, Chitra Hosing, Sherry Pierce, Meghan Anne Meyer, Xuelin Huang, Guillermo Garcia-Manero
Journal: Blood
Blood (2024) 144 (Supplement 1): 4601.
https://doi.org/10.1182/blood-2024-204040
Published: 2024
Journal Articles

Characteristics and Outcomes of Patients (pts) with Acute Myeloid Leukemia (AML) and FLT3 -Tyrosine Kinase Domain (TKD) Mutations

Sankalp Arora, Musa Yilmaz, Wei-Ying Jen, Nicholas J. Short, Sanam Loghavi, Tapan M. Kadia, Courtney D. DiNardo, Gautam Borthakur, Indraneel Deshmukh, Ghayas C. Issa, Joseph E. Jabbour, Naveen Pemmaraju, Michael Andreeff, Koichi Takahashi, Kapil N. Bhalla, Hussein A. Abbas, Guillermo Garcia-Manero, Farhad Ravandi, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 841.
https://doi.org/10.1182/blood-2024-204042
Published: 2024
Journal Articles

Early Obinutuzumab Significantly Increases Bone Marrow Undetectable MRD (10 -4 sensitivity) (uMRD4) Rate When Combined with Acalabrutinib and Venetoclax in a Randomized Phase II Trial for Treatment Naïve CLL

Mahesh Swaminathan, Philip A. Thompson, Jan A. Burger, Musa Yilmaz, Nitin Jain, Tapan M. Kadia, Lucia Masarova, Yesid Alvarado Valero, Prithviraj Bose, Alessandra Ferrajoli, Ghayas C. Issa, Steven M. Kornblau, Farhad Ravandi, Koji Sasaki, Gautam Borthakur, Kelly S. Chien, Courtney D. DiNardo, Danielle Hammond, Elias Jabbour, Guillermo Montalban-Bravo, Naveen Pemmaraju, Nicholas J. Short, Koichi Takahashi, Francesco Paolo Tambaro, Wei Qiao, Naveen Garg, Michael J. Keating, William G. Wierda
Journal: Blood
Blood (2024) 144 (Supplement 1): 1855.
https://doi.org/10.1182/blood-2024-211110
Published: 2024
Journal Articles

Distinct Impact of Platinum Chemotherapies on the Fitness and Genome of Hematopoietic Stem Cells and the Risk of Therapy-Related Myeloid Neoplasms

Jeremy Connors, Linda Zhang, Hidetaka Uryu, Koji Sasaki, Jennifer Padilla, Zongrui Li, Ken Furudate, Tomoyuki Tanaka, Courtney D. DiNardo, Nicholas J. Short, Naval Daver, Gautham Borthakur, Farhad Ravandi, Tapan M. Kadia, Hagop M. Kantarjian, Elias Jabbour, Simona Colla, Branko Cuglievan, Andrew Futreal, Adam S. Sperling, Guillermo Garcia-Manero, Margaret Goodell, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1816.
https://doi.org/10.1182/blood-2024-212052
Published: 2024
Journal Articles

Adolescents and Young Adults (AYA) with Myeloproliferative Neoplasms (MPNs): Analysis of Patient Outcomes and Impact of High-Molecular Risk Mutations

Hannah Goulart, Hagop M. Kantarjian, Lucia Masarova, Naval Daver, Elias Jabbour, Tapan M. Kadia, Guillermo Garcia-Manero, Farhad Ravandi, Courtney D. DiNardo, Sherry Pierce, Lingsha Zhou, Mahesh Swaminathan, Gautam Borthakur, Nitin Jain, Prithviraj Bose, Naveen Pemmaraju
Journal: Blood
Blood (2024) 144 (Supplement 1): 1800.
https://doi.org/10.1182/blood-2024-202606
Published: 2024