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Frederick R. Appelbaum
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Journal Articles

Genetic risk classification for adults with AML receiving less-intensive therapies: the 2024 ELN recommendations

Hartmut Döhner, Courtney D. DiNardo, Frederick R. Appelbaum, Charles Craddock, Hervé Dombret, Benjamin L. Ebert, Pierre Fenaux, Lucy A. Godley, Robert P. Hasserjian, Richard A. Larson, Ross L. Levine, Yasushi Miyazaki, Dietger Niederwieser, Gert Ossenkoppele, Christoph Röllig, Jorge Sierra, Eytan M. Stein, Martin S. Tallman, Hwei-Fang Tien, Jianxiang Wang, Agnieszka Wierzbowska, Andrew H. Wei, Bob Löwenberg
Journal: Blood
Blood (2024) 144 (21): 2169–2173.
https://doi.org/10.1182/blood.2024025409
Published: 2024
Journal Articles

Impact of Socioeconomic Factors on Access to and Outcomes of Allogeneic Hematopoietic Cell Transplantation (allo-HCT) for Acute Myeloid Leukemia (AML): A Multi-Center Observational Study

Natalie Wuliji, Ted Gooley, Salene Jones, Aaron T. Gerds, Bruno Medeiros, Paul J. Shami, John Galvin, Kehinde Adekola, Selina Luger, Maria R. Baer, David A. Rizzieri, Tanya M. Wildes, Eunice S. Wang, Mikkael A. Sekeres, Sudipto Mukherjee, Julie C. Smith, Mitchell A. Garrison, Kiarash Kojouri, Jacob S. Appelbaum, Mary-Elizabeth M. Percival, Brenda M. Sandmaier, Frederick R. Appelbaum, Mohamed Sorror
Journal: Blood
Blood (2024) 144 (Supplement 1): 6.
https://doi.org/10.1182/blood-2024-202664
Published: 2024
Journal Articles

Karyotype AI for Precision Oncology

Min Fang, Zahra Shamsi, Drew Bryant, Jacob Wilson, Xiaoyu Qu, Avinava Dubey, Konik Kothari, Mostafa Dehghani, Mariya Chavarha, Valerii Likhosherstov, Brian Williams, Michael Frumkin, Frederick R. Appelbaum, Krzysztof Choromanski, Ali Bashir
Journal: Blood
Blood (2024) 144 (Supplement 1): 1544.
https://doi.org/10.1182/blood-2024-211644
Published: 2024
Journal Articles

10 Year Follow-up of CALGB 10603/Ratify: Midostaurin Versus Placebo Plus Intensive Chemotherapy in Newly Diagnosed FLT3 Mutant Acute Myeloid Leukemia Patients Aged 18-60 Years

Richard M Stone, Jun Yin, Sumithra J Mandrekar, Axel Benner, Maral Saadati, Ilene A. Galinsky, Ben L. Sanford, Rebecca Teske, Susan M. Geyer, Thomas Prior, Sergio Amadori, Frederick R. Appelbaum, Joseph Brandwein, Konstanze Döhner, Gerhard Ehninger, Arnold Ganser, Rebecca B. Klisovic, Jürgen Krauter, Guido Marcucci, Bruno Medeiros, Dietger W. Niederwieser, Miguel A. Sanz, Richard F. Schlenk, Hubert Serve, Jorge Sierra, Martin S. Tallman, Andrew H Wei, Theo J.M. de Witte, Christian Thiede, Hartmut Döhner, Richard A. Larson
Journal: Blood
Blood (2024) 144 (Supplement 1): 218.
https://doi.org/10.1182/blood-2024-201058
Published: 2024
Journal Articles

Evaluation of ELN2022 Risk Stratification in NPM1 Mutated AML: A Study from the Fred Hutch and SWOG

Vivian M. Liu, Megan Othus, Rhonda E. Ries, Jasmine Naru, Era L. Pogosova-Agadjanyan, Frederick R. Appelbaum, Lan W. Beppu, Thomas R. Chauncey, Harry P. Erba, John E. Godwin, Matthew Fitzgibbon, Min Fang, Stanley C. Lee, Anna B. Moseley, Jerald P. Radich, Cheryl L. Willman, Feinan Wu, Soheil Meshinchi, Derek L. Stirewalt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4309.
https://doi.org/10.1182/blood-2024-198506
Published: 2024
Journal Articles

Impact of Socioeconomic Disparities on Outcomes in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia

Daniel J Olivieri, Megan Othus, Corentin Orvain, Eduardo Rodríguez-Arbolí, Filippo Milano, Brenda M. Sandmaier, Irum Khan, Chris Davis, Ryan S. Basom, Frederick R. Appelbaum, Roland B. Walter
Journal: Blood
Blood (2023) 142 (Supplement 1): 3809.
https://doi.org/10.1182/blood-2023-181244
Published: 2023
Journal Articles

Role of Measurable Residual Disease (MRD) Testing for the Prediction of Late Relapses Following Allogeneic Hematopoietic Cell Transplantation in Adult Acute Myeloid Leukemia

Naveed Ali, Othus Megan, Eduardo Rodríguez-Arbolí, Corentin Orvain, Filippo Milano, Brenda M. Sandmaier, Chris Davis, Ryan S. Basom, Frederick R. Appelbaum, Roland B. Walter
Journal: Blood
Blood (2023) 142 (Supplement 1): 4308.
https://doi.org/10.1182/blood-2023-183117
Published: 2023
Journal Articles

Allogeneic Hematopoietic Cell Transplantation in the 7 th Decade of Life and Beyond

Mary-Elizabeth M. Percival, Ted Gooley, Chris Davis, Ryan S. Basom, Stephanie J. Lee, Frederick R. Appelbaum, Mohamed Sorror
Journal: Blood
Blood (2023) 142 (Supplement 1): 3608.
https://doi.org/10.1182/blood-2023-185037
Published: 2023
Journal Articles

Relative Prognostic Value of Flow Cytometric Measurable Residual Disease before Allogeneic Hematopoietic Cell Transplantation for Adults with MDS/AML or AML

Corentin Orvain, Naveed Ali, Megan Othus, Eduardo Rodríguez-Arbolí, Filippo Milano, Brenda M. Sandmaier, Bart L. Scott, Frederick R. Appelbaum, Roland B. Walter
Journal: Blood
Blood (2023) 142 (Supplement 1): 4315.
https://doi.org/10.1182/blood-2023-188633
Published: 2023
Journal Articles

An 8-year pragmatic observation evaluation of the benefits of allogeneic HCT in older and medically infirm patients with AML

Clinical Trials & Observations
Mohamed L. Sorror, Ted A. Gooley, Barry E. Storer, Aaron T. Gerds, Mikkael A. Sekeres, Bruno C. Medeiros, Eunice S. Wang, Paul J. Shami, Kehinde Adekola, Selina Luger, Maria R. Baer, David A. Rizzieri, Tanya M. Wildes, Jamie Koprivnikar, Julie Smith, Mitchell Garrison, Kiarash Kojouri, Tammy A. Schuler, Wendy M. Leisenring, Lynn E. Onstad, Pamela S. Becker, Jeannine S. McCune, Stephanie J. Lee, Brenda M. Sandmaier, Frederick R. Appelbaum, Elihu H. Estey
Journal: Blood
Blood (2023) 141 (3): 295–308.
https://doi.org/10.1182/blood.2022016916
Published: 2023
Includes: Supplemental data
Journal Articles

Characteristics and Prognostic Effects of DNMT3A Co-Mutations

Alireza Torabi, Todd A. Alonzo, Megan Othus, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Jerald P. Radich, Frederick R. Appelbaum, Kristin O'Dwyer, Harry P. Erba, Martin S. Tallman, Mark R. Litzow, Ehab L. Atallah, Selina M. Luger, Anders E. Kolb, Omar Abdel-Wahab, Derek Stirewalt, Ross L. Levine, Elisabeth Paietta, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 745–747.
https://doi.org/10.1182/blood-2022-162526
Published: 2022
Journal Articles

Novel Data Analytics Identify Predictors of Quality-of-Life Trajectories in Patients with AML or High-Risk Myeloid Neoplasms

Jordan Gauthier, Bianca Furtuna, Jacopo Mangiavacchi, Shahrzad Gholami, Juan Lavista Ferres, Rahul Dodhia, Amir T. Fathi, Andrew M. Brunner, Aaron T. Gerds, Mikkael A. Sekeres, Bruno C. Medeiros, Eunice S. Wang, Paul J Shami, Kehinde Adekola, Selina M. Luger, Maria R. Baer, David A Rizzieri, Tanya Wildes, Jamie L. Koprivnikar, Julie Smith, Mitchell A. Garrison, Kiarash Kojouri, Frederick R. Appelbaum, Mary-Elizabeth M. Percival, Stephanie J. Lee, Mohamed L. Sorror
Journal: Blood
Blood (2022) 140 (Supplement 1): 5254–5257.
https://doi.org/10.1182/blood-2022-165437
Published: 2022
Journal Articles

Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN

Hartmut Döhner, Andrew H. Wei, Frederick R. Appelbaum, Charles Craddock, Courtney D. DiNardo, Hervé Dombret, Benjamin L. Ebert, Pierre Fenaux, Lucy A. Godley, Robert P. Hasserjian, Richard A. Larson, Ross L. Levine, Yasushi Miyazaki, Dietger Niederwieser, Gert Ossenkoppele, Christoph Röllig, Jorge Sierra, Eytan M. Stein, Martin S. Tallman, Hwei-Fang Tien, Jianxiang Wang, Agnieszka Wierzbowska, Bob Löwenberg
Journal: Blood
Blood (2022) 140 (12): 1345–1377.
https://doi.org/10.1182/blood.2022016867
Published: 2022
Journal Articles

Conditioning intensity and peritransplant flow cytometric MRD dynamics in adult AML

Clinical Trials & Observations
Gabrielle Paras, Linde M. Morsink, Megan Othus, Filippo Milano, Brenda M. Sandmaier, Lucas C. Zarling, Raffaele Palmieri, Gary Schoch, Chris Davis, Marie Bleakley, Mary E. D. Flowers, H. Joachim Deeg, Frederick R. Appelbaum, Rainer Storb, Roland B. Walter
Journal: Blood
Blood (2022) 139 (11): 1694–1706.
https://doi.org/10.1182/blood.2021014804
Published: 2022
Includes: Supplemental data
Journal Articles

Enrollment Characteristics and Outcomes of Hispanic and Black AYA ALL Patients Enrolled on a U.S. Intergroup Clinical Trial: A Comparison of the CALGB 10403 (Alliance) Cohort with U.S. Population-Level Data

Lori Muffly, Jun Yin, Sawyer Jacobson, Anjali Advani, Selina M. Luger, Martin S. Tallman, Mark R. Litzow, Matthew C. Foster, Frederick R. Appelbaum, Richard A. Larson, Theresa Keegan, Wendy Stock
Journal: Blood
Blood (2021) 138 (Supplement 1): 337.
https://doi.org/10.1182/blood-2021-148804
Published: 2021
Journal Articles

Proteogenomic Characterization of Highly Enriched Viable Leukemic Blasts in Acute Myeloid Leukemia: A SWOG Report

Jasmine Naru, Megan Othus, ChenWei Lin, Anna Moseley, Cheryl L Willman, Era L Pogosova-Agadjanyan, Feinan Wu, Frederick R. Appelbaum, Harry P. Erba, Isaac C. Jenkins, Jacob J Kennedy, Jeffrey Delrow, Jeffrey Whiteaker, Jerald P. Radich, John E. Godwin, Lan Beppu, Matthew Fitzgibbon, Min Fang, Pei Wang, Phillip R Gafken, Richard G Ivey, Soheil Meshinchi, Thomas R. Chauncey, Travis D Lorentzen, Uliana J Voytovich, Amanda G Paulovich, Derek Stirewalt
Journal: Blood
Blood (2021) 138 (Supplement 1): 522.
https://doi.org/10.1182/blood-2021-151246
Published: 2021
Journal Articles

Global Proteomic Profiling Identifies Novel Prognostic Factors in Undifferentiated Leukemia Blasts from Patients with NPM1 Mutations: A Previously Unreported Approach to Biomarker Discovery from the Fred Hutch and SWOG

Derek Stirewalt, Megan Othus, Jasmine Naru, Jacob J Kennedy, Era L Pogosova-Agadjanyan, Frederick R. Appelbaum, Lan Beppu, Thomas R. Chauncey, Jeffrey Delrow, Harry P. Erba, Phillip R Gafken, John E. Godwin, Matthew Fitzgibbon, Xing Hua, Isaac C. Jenkins, Min Fang, Richard G Ivey, ChenWei Lin, Travis D Lorentzen, Anna Moseley, Jerald P. Radich, Uliana J Voytovich, Pei Wang, Jeffrey Whiteaker, Cheryl L Willman, Feinan Wu, Soheil Meshinchi, Amanda G Paulovich
Journal: Blood
Blood (2021) 138 (Supplement 1): 799.
https://doi.org/10.1182/blood-2021-151678
Published: 2021
Journal Articles

Multisite 11-year experience of less-intensive vs intensive therapies in acute myeloid leukemia

Clinical Trials & Observations
Mohamed L. Sorror, Barry E. Storer, Amir T. Fathi, Andrew Brunner, Aaron T. Gerds, Mikkael A. Sekeres, Sudipto Mukherjee, Bruno C. Medeiros, Eunice S. Wang, Pankit Vachhani, Paul J. Shami, Esteban Peña, Mahmoud Elsawy, Kehinde Adekola, Selina Luger, Maria R. Baer, David Rizzieri, Tanya M. Wildes, Jamie Koprivnikar, Julie Smith, Mitchell Garrison, Kiarash Kojouri, Wendy Leisenring, Lynn Onstad, Jennifer E. Nyland, Pamela S. Becker, Jeannine S. McCune, Stephanie J. Lee, Brenda M. Sandmaier, Frederick R. Appelbaum, Elihu H. Estey
Journal: Blood
Blood (2021) 138 (5): 387–400.
https://doi.org/10.1182/blood.2020008812
Published: 2021
Includes: Supplemental data
Journal Articles

Characteristics and Prognostic Effects of IDH Mutations across the Age Spectrum in AML: A Collaborative Analysis from COG, SWOG, and ECOG

Sara Zarnegar-Lumley, MD, Todd A. Alonzo, PhD, Megan Othus, PhD, Zhuoxin Sun, PhD, Rhonda E. Ries, MA, Yi-Cheng Wang, MS, Amanda R. Leonti, MS, Matthew A. Kutny, MD, Derek Stirewalt, MD, Jerald P. Radich, MD, Frederick R. Appelbaum, MD, Era L Pogosova-Agadjanyan, BS, Kristen Marie O'Dwyer, MD, Harry P. Erba, MD PhD, Omar Abdel-Wahab, MD, Martin S. Tallman, MD, Mark Litzow, MD, Ehab L. Atallah, MD, Selina M. Luger, MD FRCPC, Ross L. Levine, MD, Todd M. Cooper, DO, Alan S. Gamis, MD MPH, Richard Aplenc, MD PhD, Anders E. Kolb, MD, Soheil Meshinchi, MDPhD, Katherine Tarlock, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-134211
Published: 2020
Journal Articles

A Multi-Center Biologic Assignment Trial Comparing Reduced Intensity Allogeneic Hematopoietic Cell Transplantation to Hypomethylating Therapy or Best Supportive Care in Patients Aged 50-75 with Advanced Myelodysplastic Syndrome: Blood and Marrow Transplant Clinical Trials Network Study 1102

Ryotaro Nakamura, MD, Wael Saber, MD MS, Michael J Martens, PhD, Alyssa Ramirez, Bart L. Scott, MD, Betul Oran, MDMS, Eric Leifer, PhD, Roni Tamari, MD, Asmita Mishra, MD, Richard T. Maziarz, MD, Joseph P. McGuirk, DO, Peter Westervelt, MD PhD, Sumithra Vasu, MDMBBS, Mrinal M. Patnaik, MDMBBS, Rammurti Kamble, MD, Stephen J. Forman, MD, Mikkael A. Sekeres, Frederick R. Appelbaum, MD, Adam M. Mendizabal, MS, Brent Logan, PhD, Mary M. Horowitz, MD MS, Corey Cutler, MD MPH, FRCPC
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–21.
https://doi.org/10.1182/blood-2020-136828
Published: 2020