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Journal Articles

Impact of MDS-associated mutations and age on outcomes in NPM1-mutated AML

Vivian Liu, Megan Othus, Rhonda Ries, Jasmine Naru, Era Pogosova-Agadjanyan, Frederick Appelbaum, Lan Beppu, Thomas Chauncey, Harry Erba, John Godwin, Matthew Fitzgibbon, Min Fang, Stanley Lee, Anna Moseley, Jerald Radich, Cheryl Willman, Feinan Wu, Soheil Meshinchi, Derek Stirewalt

Blood (2025) 146 (Supplement 1): 6999.

https://doi.org/10.1182/blood-2025-6999

Published: 2025

Journal Articles

Chromosome genomic array testing (CGAT) improves diagnostic yield in patients with AML and MDS and has the potential for better risk stratefication - an NCI myelomatch and SWOG report

Min Fang, Megan Othus, Xiaoyu QU, Kate Kroeger, Jacob Wilson, Alyssa Ng, Cecilia Yeung, Shahanawaz Jiwani, Lyndsay Harris, Brent Wood, Harry Erba, Jerald Radich, Richard Little

Blood (2025) 146 (Supplement 1): 3501.

https://doi.org/10.1182/blood-2025-3501

Published: 2025

Journal Articles

Improving karyotype success for myelomatch: Evidence-based culturing optimization for rapid AML screening - an NCI myelomatch and SWOG report

Xiaoyu QU, Shane McClung, Nicole Shepherd, Kate Kroeger, Beverly Hale, Othus Megan, Harry Erba, Lyndsay Harris, Richard Little, Jerald Radich, Min Fang

Blood (2025) 146 (Supplement 1): 3473.

https://doi.org/10.1182/blood-2025-3473

Published: 2025

Journal Articles

Myeloid malignancies molecular analysis for therapy choice (myeloMATCH): Rapid availability of clinical, pathologic and molecular features for treatment assignment in the first 550 patients.

Blood (2025) 146 (Supplement 1): 5279.

https://doi.org/10.1182/blood-2025-5279

Published: 2025

Journal Articles

Biallelic TP53 aberrations and double TP53 mutations are prevalent in AML/MDS patients with del(5q) complex karyotype - an NCI myelomatch and SWOG report

Min Fang, Megan Othus, Kate Kroeger, Thaiha Nguyen, Xiaoyu QU, Brent Wood, Lyndsay Harris, Harry Erba, Jerald Radich, Richard Little, Cecilia Yeung, Shahanawaz Jiwani

Blood (2025) 146 (Supplement 1): 5276.

https://doi.org/10.1182/blood-2025-5276

Published: 2025

Journal Articles

Identifying fusions in AML/MDS: An experience from first 400 patients enrolled into myelomatch

Shahanawaz Jiwani, Min Fang, Cecilia Yeung, Xiaoyu QU, Xueyan Chen, Brent Wood, Andrea Zak, Srikrishna Narava, Ting-Chia Chang, Celso Baldivieso, Megha Kamath, Megan Othus, Bhanumati Ramineni, Harry Erba, Mark Litzow, James Doroshow, Lyndsay Harris, Jerald Radich, Richard Little

Blood (2025) 146 (Supplement 1): 340.

https://doi.org/10.1182/blood-2025-340

Published: 2025

Journal Articles

Genomic Proximity Mapping (GPM): Evaluation of a Next Generation Cytogenomic Assay for Improved Risk Stratification in Acute Myeloid Leukemia

Blood (2024) 144 (Supplement 1): 6157.

https://doi.org/10.1182/blood-2024-211570

Published: 2024

Journal Articles

Karyotype AI for Precision Oncology

Min Fang, Zahra Shamsi, Drew Bryant, Jacob Wilson, Xiaoyu Qu, Avinava Dubey, Konik Kothari, Mostafa Dehghani, Mariya Chavarha, Valerii Likhosherstov, Brian Williams, Michael Frumkin, Frederick R. Appelbaum, Krzysztof Choromanski, Ali Bashir

Blood (2024) 144 (Supplement 1): 1544.

https://doi.org/10.1182/blood-2024-211644

Published: 2024

Journal Articles

Loss of 5q Drives Evolution to Aneuploidy in an iPSC Model of Complex Karyotype AML

J. Philip Creamer, Suhita Ray, Sintra Stewart, Jacob S. Appelbaum, Min Fang, Elizabeth Swisher, Sergei Doulatov

Blood (2024) 144 (Supplement 1): 629.

https://doi.org/10.1182/blood-2024-206210

Published: 2024

Journal Articles

4q Copy Neutral Loss of Heterozygosity and KMT2A Partial Tandem Duplication Identified By Chromosomal Genomic Array Testing (CGAT) Correlated with Decreased Overall Survival in Acute Myeloid Leukemia (AML)

Suravi Raychaudhuri, Ted Gooley, Megan Othus, Xiaoyu Qu, Carole Shaw, Kathryn Russell, Rutu D. Vyas, Jacob S. Appelbaum, Anna B. Halpern, Roland B. Walter, Harry P. Erba, Min Fang, Mary-Elizabeth M. Percival

Blood (2024) 144 (Supplement 1): 1530.

https://doi.org/10.1182/blood-2024-201213

Published: 2024

Journal Articles

Evaluation of ELN2022 Risk Stratification in NPM1 Mutated AML: A Study from the Fred Hutch and SWOG

Vivian M. Liu, Megan Othus, Rhonda E. Ries, Jasmine Naru, Era L. Pogosova-Agadjanyan, Frederick R. Appelbaum, Lan W. Beppu, Thomas R. Chauncey, Harry P. Erba, John E. Godwin, Matthew Fitzgibbon, Min Fang, Stanley C. Lee, Anna B. Moseley, Jerald P. Radich, Cheryl L. Willman, Feinan Wu, Soheil Meshinchi, Derek L. Stirewalt

Blood (2024) 144 (Supplement 1): 4309.

https://doi.org/10.1182/blood-2024-198506

Published: 2024

Journal Articles

Prognostic Value of Copy Number Aberrations and Copy Neutral Loss of Heterozygosity in Acute Myeloid Leukemia

Suravi Raychaudhuri, Ted Gooley, Xiaoyu Qu, Carole Shaw, Kathryn Russell, Rutu D. Vyas, Jacob S. Appelbaum, Anna B. Halpern, Roland B. Walter, Min Fang, Mary-Elizabeth M. Percival

Blood (2023) 142 (Supplement 1): 2945.

https://doi.org/10.1182/blood-2023-184402

Published: 2023

Journal Articles

Resistance to CD38 Antigen Targeted Therapy in Multiple Myeloma May Result from Underrecognized Chromosome 4 Gene Deletions

Andrew J Portuguese, Min Fang, Sherilyn A. Tuazon, Margot Pont, Xiaoyu Qu, Carolyn Shasha, Melissa L Comstock, Justina Lyons, Gabriel Cole, Evan W. Newell, Emily Glynn, Lorinda Soma, Damian J Green

Blood (2023) 142 (Supplement 1): 1976.

https://doi.org/10.1182/blood-2023-186688

Published: 2023

Journal Articles

Prognostic Significance of Chromosomal Genomic Array Testing in Adults with Newly Diagnosed Acute Lymphoblastic Leukemia

Noam E. Kopmar, Xiaoyu Qu, Yajuan J. Liu, Ted A. Gooley, Lucas Zarling, Mary-Elizabeth M. Percival, Cristina Ghiuzeli, Min Fang, Ryan D. Cassaday

Blood (2022) 140 (Supplement 1): 9196–9197.

https://doi.org/10.1182/blood-2022-168183

Published: 2022

Journal Articles

Global Proteomic Profiling Identifies Novel Prognostic Factors in Undifferentiated Leukemia Blasts from Patients with NPM1 Mutations: A Previously Unreported Approach to Biomarker Discovery from the Fred Hutch and SWOG

Blood (2021) 138 (Supplement 1): 799.

https://doi.org/10.1182/blood-2021-151678

Published: 2021

Journal Articles

Loss of Lamin B1 in Myeloid Neoplasms with 5q Deletion Causes Myeloid-Biased Hematopoiesis and Pelger-Huet Nuclear Anomaly

Andreea Reilly, J. Philip Creamer, Massiel Chavez Stolla, Yuchuan Wang, Jing Du, Rachel Wellington, Stephanie Busch, Elihu H. Estey, Pamela S. Becker, Min Fang, Sioban B. Keel, Janis L. Abkowitz, Lorinda A. Soma, Jian Ma, Zhijun Duan, Sergei Doulatov

Blood (2021) 138 (Supplement 1): 502.

https://doi.org/10.1182/blood-2021-154121

Published: 2021

Journal Articles

Proteogenomic Characterization of Highly Enriched Viable Leukemic Blasts in Acute Myeloid Leukemia: A SWOG Report

Blood (2021) 138 (Supplement 1): 522.

https://doi.org/10.1182/blood-2021-151246

Published: 2021

Journal Articles

Reduced-Intensity Therapy with Dose-Adjusted Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) Yields Durable Remissions in Adults with Newly-Diagnosed Acute Lymphoblastic Leukemia/Lymphoma (ALL): Final Results of a Phase II Trial

Ryan D. Cassaday, Kelsey-Leigh A. Garcia, Olga Sala-Torra, Philip A. Stevenson, Christen H. Martino, Yajuan J. Liu, Min Fang, Mary-Elizabeth M. Percival, Anna B. Halpern, Pamela S. Becker, Vivian G. Oehler, Andrei R Shustov, Jason P. Cooper, Johnnie J. Orozco, Paul C. Hendrie, Roland B. Walter, Jerry P. Radich, Lorinda A. Soma, Elihu H. Estey

Blood (2021) 138 (Supplement 1): 4397.

https://doi.org/10.1182/blood-2021-145648

Published: 2021

Journal Articles

Pembrolizumab with R-CHOP in Previously Untreated Diffuse Large B-Cell Lymphoma: Long Term Follow up and Analysis of the Mechanism of Pdl-1 Tumor Expression

Stephen D. Smith, MD, Jonathan R. Fromm, MD PhD, Min Fang, MD PhD, Brian G. Till, MD, Mazyar Shadman, MDMPH, Ryan C. Lynch, MD, Andrew J. Cowan, MD, Qian Vicky Wu, PhD, Jenna Voutsinas, MPH, Heather A. Rasmussen, BS, Katie Blue, Chaitra S. Ujjani, MD, Andrei R Shustov, MD, Ryan D. Cassaday, MD, Ajay K. Gopal, MD

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-137328

Published: 2020

Journal Articles

Accrual Barriers and Detection of Early Toxicity Signal in Older Less-Fit Patients Treated with Azacitidine and Nivolumab for Newly Diagnosed Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) in the SWOG 1612 Platform Randomized Phase II/III Clinical Trial

Annette E. Hay, Sarit Assouline, MD, Roland B. Walter, MD PhD MS, Richard F. Little, MD MPH, Anna Moseley, M.S., Sperling M Gail, MPH, CHES, Annie Im, MD, James M. Foran, MD, Jerald P. Radich, MD, Min Fang, MD PhD, Megan Othus, PhD, Harry P. Erba, MD PhD, Laura C. Michaelis, MD

Blood (2019) 134 (Supplement_1): 3905.

https://doi.org/10.1182/blood-2019-124320

Published: 2019

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Impact of MDS-associated mutations and age on outcomes in NPM1-mutated AML

Chromosome genomic array testing (CGAT) improves diagnostic yield in patients with AML and MDS and has the potential for better risk stratefication - an NCI myelomatch and SWOG report

Improving karyotype success for myelomatch: Evidence-based culturing optimization for rapid AML screening - an NCI myelomatch and SWOG report

Myeloid malignancies molecular analysis for therapy choice (myeloMATCH): Rapid availability of clinical, pathologic and molecular features for treatment assignment in the first 550 patients.

Biallelic TP53 aberrations and double TP53 mutations are prevalent in AML/MDS patients with del(5q) complex karyotype - an NCI myelomatch and SWOG report

Identifying fusions in AML/MDS: An experience from first 400 patients enrolled into myelomatch

Genomic Proximity Mapping (GPM): Evaluation of a Next Generation Cytogenomic Assay for Improved Risk Stratification in Acute Myeloid Leukemia

Karyotype AI for Precision Oncology

Loss of 5q Drives Evolution to Aneuploidy in an iPSC Model of Complex Karyotype AML

4q Copy Neutral Loss of Heterozygosity and KMT2A Partial Tandem Duplication Identified By Chromosomal Genomic Array Testing (CGAT) Correlated with Decreased Overall Survival in Acute Myeloid Leukemia (AML)

Evaluation of ELN2022 Risk Stratification in NPM1 Mutated AML: A Study from the Fred Hutch and SWOG

Prognostic Value of Copy Number Aberrations and Copy Neutral Loss of Heterozygosity in Acute Myeloid Leukemia

Resistance to CD38 Antigen Targeted Therapy in Multiple Myeloma May Result from Underrecognized Chromosome 4 Gene Deletions

Prognostic Significance of Chromosomal Genomic Array Testing in Adults with Newly Diagnosed Acute Lymphoblastic Leukemia

Global Proteomic Profiling Identifies Novel Prognostic Factors in Undifferentiated Leukemia Blasts from Patients with NPM1 Mutations: A Previously Unreported Approach to Biomarker Discovery from the Fred Hutch and SWOG

Loss of Lamin B1 in Myeloid Neoplasms with 5q Deletion Causes Myeloid-Biased Hematopoiesis and Pelger-Huet Nuclear Anomaly

Proteogenomic Characterization of Highly Enriched Viable Leukemic Blasts in Acute Myeloid Leukemia: A SWOG Report

Reduced-Intensity Therapy with Dose-Adjusted Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) Yields Durable Remissions in Adults with Newly-Diagnosed Acute Lymphoblastic Leukemia/Lymphoma (ALL): Final Results of a Phase II Trial

Pembrolizumab with R-CHOP in Previously Untreated Diffuse Large B-Cell Lymphoma: Long Term Follow up and Analysis of the Mechanism of Pdl-1 Tumor Expression

Accrual Barriers and Detection of Early Toxicity Signal in Older Less-Fit Patients Treated with Azacitidine and Nivolumab for Newly Diagnosed Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) in the SWOG 1612 Platform Randomized Phase II/III Clinical Trial

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