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Ryan D. Cassaday
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Journal Articles

Autoimmune Outcomes in Patients with Concurrent Autoimmune Disease Receiving CD19 CAR T-Cell Therapy for Lymphoma

Jennifer J. Huang, Namrata Singh, Mazyar Shadman, Ryan S. Basom, Andrea Kalus, Andrew J Portuguese, Emily C Liang, Natalie Wuliji, Alexandre V. Vinaud Hirayama, Aude G Chapuis, Folashade Otegbeye, Filippo Milano, Ryan D. Cassaday, Ajay K. Gopal, Brian G. Till, Edus H. Warren, Jordan Gauthier, Lawrence Fong, David G. Maloney
Journal: Blood
Blood (2024) 144 (Supplement 1): 7132.
https://doi.org/10.1182/blood-2024-201809
Published: 2024
Journal Articles

NGS MRD Negativity on Day 28 after Brexu Cel in Adults with R/R ALL Is Associated with Favorable Progression Free Survival

Yannis K. Valtis, David Nemirovsky, Sean M. Devlin, Gregory W Roloff, Ibrahim Aldoss, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Anjali S. Advani, Marlise R. Luskin, Evan C. Chen, Omer Jamy, Michael R. Grunwald, Ibrahim Muhsen, Noam E. Kopmar, Bhagirathbhai Dholaria, Simone E. Dekker, Jessica T. Leonard, George Yaghmour, Stephanie B. Tsai, Wendy Stock, Jozal Moore, Kristen M. O'Dwyer, Aaron C. Logan, Matthew P Connor, Noelle Frey, Evandro Bezerra, Sumithira Vasu, Kaitlyn C Dykes, Minoo Battiwalla, Chenyu Lin, Matthew Ulrickson, Ran Reshef, Ryan D. Cassaday, Laquisha C. Hill, Catherine J. Lee, Vamsi K. Kota, Jacob Boccucci, Joshua Sasine, Akil Merchant, Vinod Pullarkat, Amelia Langston, Talal Hilal, Rawan Faramand, Melhem M. Solh, Tamer Othman, Timothy E O'Connor, Navneet Majhail, Shabaz Malik, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Muthu V. Kumaran, Marc Schwartz, Veronika Bachanova, Sean I. Tracy, Maria Odstrcil Bobillo, Abdullah Ladha, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Michael Daunov, John Mathews, Paul Shaughnessy, Bijal D Shah, Lori Muffly, Jae H. Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 4200.
https://doi.org/10.1182/blood-2024-201610
Published: 2024
Journal Articles

Phase I Trial Combining Venetoclax with Cladribine, Cytarabine, G-CSF, and Mitoxantrone (CLAG-M) for Patients with Acute Myeloid Leukemia (AML) and High-Grade Myeloid Neoplasms

Suravi Raychaudhuri, Ted Gooley, Allegra Rasmussen, Kim Quach, Zach Gill, Anna B. Halpern, Jacob S. Appelbaum, Cristina Maria Ghiuzeli, Paul C. Hendrie, Ryan D. Cassaday, Roland B. Walter, Elihu Estey, Mary-Elizabeth M. Percival
Journal: Blood
Blood (2024) 144 (Supplement 1): 4288.
https://doi.org/10.1182/blood-2024-200883
Published: 2024
Journal Articles

Extended Follow-up of Dose-Adjusted EPOCH (DA-EPOCH) Plus Inotuzumab Ozogamicin (InO) in Adults with Relapsed/Refractory (R/R) B-Cell Acute Lymphoblastic Leukemia (B-ALL): A Safe and Effective Salvage Therapy

Noam E. Kopmar, Henry Le, Kim Quach, Ted Gooley, Christen Martino, Ashtyn Sherrow, Sindhu Cherian, Mary-Elizabeth M. Percival, Anna B. Halpern, Cristina Maria Ghiuzeli, Janis L. Abkowitz, Roland B. Walter, Ryan D. Cassaday
Journal: Blood
Blood (2024) 144 (Supplement 1): 4209.
https://doi.org/10.1182/blood-2024-208875
Published: 2024
Journal Articles

Dose Optimization of Inotuzumab Ozogamicin in Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Daniel J. DeAngelo, Ying Chen, Ryan D. Cassaday, Jennifer Hibma, Derek Z Yang, May Garrett, Fan Zhang, Svetoslav H Dimitrov, Erik Vandendries, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 732.
https://doi.org/10.1182/blood-2024-194244
Published: 2024
Journal Articles

Single-Agent Subcutaneous Blinatumomab for Advanced B-Cell Acute Lymphoblastic Leukemia: Long-Term Follow-up from a Phase 1b Dose Expansion Cohort

Elias Jabbour, Gerhard Zugmaier, Pilar Martinez Sanchez, Jose J. Rifon, Vaibhav Agrawal, Ryan D Cassaday, Thomas Cluzeau, Françoise Huguet, Vladan Vucinic, Boris Böll, Anita W. Rijneveld, Mar Tormo, Maher Abdul-Hay, Paul R Gordon, Alessandro Rambaldi, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 1440.
https://doi.org/10.1182/blood-2024-205662
Published: 2024
Journal Articles

Efficacy and Safety of Brexucabtagene Autoleucel for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in Patients Aged 60 and Above

Ibrahim Muhsen, Anjali S. Advani, Gregory W Roloff, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Michael R. Grunwald, Vamsi K. Kota, Jacob Boccucci, Matthew Ulrickson, Joshua Sasine, Ibrahim Aldoss, Tamer Othman, Sumithira Vasu, Ran Reshef, Marlise R. Luskin, Evan C. Chen, Chenyu Lin, Amelia Langston, Ryan D. Cassaday, Noam E. Kopmar, Stephanie B. Tsai, Timothy E O'Connor, Talal Hilal, Rawan Faramand, Jae H. Park, Yannis K. Valtis, Melhem M. Solh, Evandro Bezerra, Jessica T. Leonard, Simone E. Dekker, Navneet Majhail, Minoo Battiwalla, Shahbaz A. Malik, John Mathews, Paul Shaughnessy, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Kaitlyn C Dykes, Aaron C. Logan, Muthu V. Kumaran, Wendy Stock, Marc Schwartz, Veronika Bachanova, Sean Tracy, Kristen M. O'Dwyer, Jozal Moore, Catherine J. Lee, Maria Silvina Odstrcil Bobillo, Noelle Frey, Matthew P Connor, Omer Jamy, Michael Daunov, Abdullah Ladha, George Yaghmour, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Bhagirathbhai Dholaria, Vinod Pullarkat, Akil Merchant, Bijal D Shah, Lori Muffly, LaQuisa Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 523.
https://doi.org/10.1182/blood-2024-210682
Published: 2024
Journal Articles

Dose-Dense Brentuximab Vedotin Plus Ifosfamide, Carboplatin, and Etoposide (ICE) in Second Line Treatment of Relapsed/Refractory Classical Hodgkin Lymphoma: 5-Year Long Term Follow up

Ryan C. Lynch, Ryan D. Cassaday, Stephen D. Smith, Andrew J. Cowan, Edus H. Warren, Mazyar Shadman, Brian G. Till, Chaitra S. Ujjani, Karolyn Morris, Heather Rasmussen, Jenna M. Voutsinas, Ajay K. Gopal
Journal: Blood
Blood (2024) 144 (Supplement 1): 3043.
https://doi.org/10.1182/blood-2024-206047
Published: 2024
Journal Articles

HA-1–targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation

Clinical Trials & Observations
Elizabeth F. Krakow, Michelle Brault, Corinne Summers, Tanya M. Cunningham, Melinda A. Biernacki, R. Graeme Black, Kyle B. Woodward, Nicole Vartanian, Sami B. Kanaan, Albert C. Yeh, Robson G. Dossa, Merav Bar, Ryan D. Cassaday, Ann Dahlberg, Brian G. Till, Andrew E. Denker, Cecilia C. S. Yeung, Ted A. Gooley, David G. Maloney, Stanley R. Riddell, Philip D. Greenberg, Aude G. Chapuis, Evan W. Newell, Scott N. Furlan, Marie Bleakley
Journal: Blood
Blood (2024) 144 (10): 1069–1082.
https://doi.org/10.1182/blood.2024024105
Published: 2024
Includes: Supplemental data
Journal Articles

Treatment Outcomes for Adults with Mixed Phenotypic Acute Leukemia: A Large Single-Center Retrospective Study

Jennifer J. Huang, Jacob S. Appelbaum, Kathryn Russell, Carole Shaw, Ashley M. Eckel, Xueyan Chen, Rutu D. Vyas, Paul C. Hendrie, Anna B. Halpern, Raya Mawad, Ryan D Cassaday, Roland B. Walter, Mary-Elizabeth M. Percival, Cristina Maria Ghiuzeli
Journal: Blood
Blood (2023) 142 (Supplement 1): 2838.
https://doi.org/10.1182/blood-2023-188461
Published: 2023
Journal Articles

The Impact of Inotuzumab Ozogamicin (InO) Treatment on Brexucabtagene Autoleucel (Brexu-cel) Outcomes in Adults with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Ibrahim Aldoss, Gregory W Roloff, Anjali S. Advani, Noam E. Kopmar, Chenyu Lin, Simone E. Dekker, Vishal K Gupta, Nikeshan Jeyakumar, Timothy E O'Connor, Amy Zhang, Katharine Miller, Kaitlyn C Dykes, Mohamed Ahmed, Hector Zambrano, Danielle Bradshaw, Santiago Mercadal, Marc Schwartz, Sean Tracy, Bhagirathbhai Dholaria, Michal Kubiak, Akash Mukherjee, Navneet Majhail, Minoo Battiwalla, Luke Mountjoy, Shahbaz A. Malik, John Mathews, Paul Shaughnessy, Aaron C. Logan, Abdullah Ladha, George Yaghmour, Maryann Stefan, Caitlin Guzowski, Rasmus T. Hoeg, Talal Hilal, Jozal Moore, Kristen M. O'Dwyer, Stephanie B. Tsai, Joshua Sasine, Melhem M. Solh, Catherine J. Lee, Vamsi K. Kota, Divya Koura, Muthu Veeraputhiran, Betsy Blunk, Jessica T. Leonard, Caspian H. Oliai, Veronika Bachanova, Wendy Stock, Ahmed Galal, Vinod Pullarkat, Ryan D Cassaday, Bijal D. Shah, Rawan Faramand, Lori S. Muffly
Journal: Blood
Blood (2023) 142 (Supplement 1): 4877.
https://doi.org/10.1182/blood-2023-182404
Published: 2023
Journal Articles

Phase 2 Study of CD19 CAR T Cells with a Fully Human Binder for Large B-Cell Lymphoma in Relapse or Progression after a Murine Binder-Bearing CD19 CAR T-Cell Therapy

Jordan Gauthier, Jennifer J. Huang, Carla Jaeger-Ruckstuhl, Emily C Liang, Aya Albittar, Andrew J Portuguese, Qian Wu, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, Christina Poh, Ajay K Gopal, Stanley R. Riddell, David G Maloney, Cameron J. Turtle
Journal: Blood
Blood (2023) 142 (Supplement 1): 6860.
https://doi.org/10.1182/blood-2023-181273
Published: 2023
Journal Articles

Factors Associated with Prolonged CRS and Neurotoxicity after Treatment with Axicabtagene Ciloleucel

Aya Albittar, Jenna M Voutsinas, Andrew J Portuguese, Jennifer J. Huang, Emily C Liang, Qian Wu, Xinyi Fan, Alexandre V Hirayama, Erik L Kimble, Lorenzo Iovino, Christina Poh, Ajay K Gopal, Mazyar Shadman, Brian G Till, Filippo Milano, Aude G Chapuis, Ryan D Cassaday, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 2126.
https://doi.org/10.1182/blood-2023-180128
Published: 2023
Journal Articles

Impact of Prior Response to Blinatumomab on Outcomes of Brexucabtagene Autoleucel (Brexu-cel) in Adult Patients with Relapsed or Refractory (r/r) B-Cell Acute Lymphoblastic Leukemia (B-ALL): Results from the Real-World Outcomes Collaborative of CAR-T in Adult ALL (ROCCA)

Vishal K Gupta, Gregory W Roloff, Lori S. Muffly, Ibrahim Aldoss, Noam E. Kopmar, Chenyu Lin, Simone E. Dekker, Nikeshan Jeyakumar, Timothy E O'Connor, Amy Zhang, Katharine Miller, Kaitlyn C Dykes, Mohamed Ahmed, Danielle Bradshaw, Santiago Mercadal, Marc Schwartz, Sean Tracy, Bhagirathbhai Dholaria, Michal Kubiak, Akash Mukherjee, Navneet Majhail, Minoo Battiwalla, Luke Mountjoy, Shabaz Malik, John Mathews, Paul Shaughnessy, Aaron C. Logan, Abdullah Ladha, George Yaghmour, Anjali S. Advani, Maryann Stefan, Caitlin Guzowski, Rasmus T. Hoeg, Talal Hilal, Jozal Moore, Kristen M. O'Dwyer, Stephanie B. Tsai, Joshua Sasine, Catherine J. Lee, Vamsi K. Kota, Divya Koura, Muthu Veeraputhiran, Betsy Blunk, Jessica T. Leonard, Wendy Stock, Ahmed Galal, Vinod Pullarkat, Ryan D Cassaday, Bijal D. Shah, Rawan Faramand, Caspian H. Oliai
Journal: Blood
Blood (2023) 142 (Supplement 1): 2119.
https://doi.org/10.1182/blood-2023-182915
Published: 2023
Journal Articles

Brexucabtagene Autoleucel in Adults with Relapsed/Refractory B-Cell ALL: Outcomes and Novel Insights from the Real-World Outcomes Collaborative of CAR T in Adult ALL (ROCCA)

Gregory W Roloff, Ibrahim Aldoss, Noam E. Kopmar, Chenyu Lin, Simone E. Dekker, Vishal K Gupta, Nikeshan Jeyakumar, Timothy E O'Connor, Amy Zhang, Katharine Miller, Kaitlyn C Dykes, Mohamed Ahmed, Hector Zambrano, Danielle Bradshaw, Santiago Mercadal, Marc Schwartz, Sean Tracy, Bhagirathbhai Dholaria, Michal Kubiak, Akash Mukherjee, Navneet Majhail, Minoo Battiwalla, Luke Mountjoy, Shahbaz A. Malik, John Mathews, Paul Shaughnessy, Aaron C. Logan, Abdullah Ladha, George Yaghmour, Anjali S. Advani, Maryann Stefan, Caitlin Guzowski, Rasmus T. Hoeg, Talal Hilal, Jozal Moore, Kristen M. O'Dwyer, Stephanie B. Tsai, Joshua Sasine, Melhem M. Solh, Catherine J. Lee, Vamsi K. Kota, Divya Koura, Muthu Veeraputhiran, Betsy Blunk, Jessica T. Leonard, Veronika Bachanova, Wendy Stock, Ahmed Galal, Vinod Pullarkat, Ryan D Cassaday, Bijal D. Shah, Rawan Faramand, Lori S. Muffly
Journal: Blood
Blood (2023) 142 (Supplement 1): 1030.
https://doi.org/10.1182/blood-2023-182531
Published: 2023
Journal Articles

Machine Learning-Based Time-Series Clustering Identifies Archetypal Trajectories of Hematotoxicity after CAR T-Cell Therapy

Emily C Liang, Aya Albittar, Andrew J Portuguese, Jennifer J. Huang, Qian Wu, Joseph De Los Reyes, Nikki Pin, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Joshua A. Hill, Rahul Banerjee, Andrew J. Cowan, Damian J Green, Ajay K Gopal, Christina Poh, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 2143.
https://doi.org/10.1182/blood-2023-174106
Published: 2023
Journal Articles

Day +3/Day 0 Ferritin Ratio: A Simple Point-of-Care Index Predictive of Severe Immune Effector Cell-Associated Neurotoxicity Syndrome after CD19 CAR T-Cell Therapy

Jennifer J. Huang, Emily C Liang, Aya Albittar, Andrew J Portuguese, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, Cameron J. Turtle, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 3495.
https://doi.org/10.1182/blood-2023-182597
Published: 2023
Journal Articles

Toxicity Profile of Brexucabtagene Autoleucel (brexu-cel; CD19-directed CAR T-cell therapy) in Adult Patients (pts) with Relapsed/Refractory (R/R) B-Cell Acute Lymphoblastic Leukemia (B-ALL): Results from a Multicenter Real-World Outcomes Study

Noam E. Kopmar, Ted Gooley, Gregory W Roloff, Ibrahim Aldoss, Chenyu Lin, Simone E. Dekker, Vishal K Gupta, Nikeshan Jeyakumar, Timothy O'connor, Kaitlyn C Dykes, Mohamed Ahmed, Hector Zambrano, Danielle Bradshaw, Santiago Mercadal, Marc Schwartz, Sean Tracy, Bhagirathbhai Dholaria, Michal Kubiak, Akash Mukherjee, Navneet Majhail, Minoo Battiwalla, Luke Mountjoy, Shabaz Malik, Paul Shaughnessy, John Mathews, Aaron C. Logan, Abdullah Ladha, George Yaghmour, Anjali S. Advani, Maryann Stefan, Caitlin Guzowski, Rasmus T. Hoeg, Talal Hilal, Jozal Moore, Kristen M. O'Dwyer, Stephanie B. Tsai, Joshua Sasine, Melhem M. Solh, Catherine J. Lee, Vamsi K. Kota, Divya Koura, Muthu Veeraputhiran, Betsy Blunk, Jessica T. Leonard, Caspian H. Oliai, Veronika Bachanova, Wendy Stock, Ahmed Galal, Vinod Pullarkat, Bijal D. Shah, Rawan Faramand, Lori S. Muffly, Ryan D Cassaday
Journal: Blood
Blood (2023) 142 (Supplement 1): 522.
https://doi.org/10.1182/blood-2023-185107
Published: 2023
Journal Articles

The Impact of Social Determinants of Health on Brexucabtagene Autoleucel Outcomes in Adults with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Timothy E O'Connor, Chenyu Lin, Gregory W Roloff, Amy Zhang, Ibrahim Aldoss, Rawan Faramand, Noam E. Kopmar, Kaitlyn C Dykes, Nikeshan Jeyakumar, Simone E. Dekker, Vishal K Gupta, Mohamed Ahmed, Aaron C. Logan, Hector Zambrano, Danielle Bradshaw, Santiago Mercadal, Marc Schwartz, Sean Tracy, Michal Kubiak, Akash Mukherjee, Navneet Majhail, Minoo Battiwalla, Luke Mountjoy, Shabaz Malik, John Mathews, Paul Shaughnessy, Abdullah Ladha, George Yaghmour, Anjali S. Advani, Maryann Stefan, Caitlin Guzowski, Rasmus T. Hoeg, Talal Hilal, Jozal Moore, Joshua Sasine, Melhem M. Solh, Catherine J. Lee, Vamsi K. Kota, Divya Koura, Muthu Veeraputhiran, Betsy Blunk, Jessica T. Leonard, Caspian H. Oliai, Veronika Bachanova, Wendy Stock, Ryan D Cassaday, Bijal D. Shah, Katharine Miller, Lori S. Muffly, Ahmed Galal, Stephanie B. Tsai, Bhagirathbhai Dholaria
Journal: Blood
Blood (2023) 142 (Supplement 1): 671.
https://doi.org/10.1182/blood-2023-182566
Published: 2023
Journal Articles

Lisocabtagene Maraleucel Versus Axicabtagene Ciloleucel: Efficacy and Toxicity in a Real-World Setting

Andrew J Portuguese, Aya Albittar, Emily C Liang, Jennifer J. Huang, Alexandre V Hirayama, Erik L Kimble, Lorenzo Iovino, Christina Poh, Ajay K Gopal, Mazyar Shadman, Brian G Till, Hans-Peter Kiem, Filippo Milano, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, David G Maloney, Jordan Gauthier
Journal: Blood
Blood (2023) 142 (Supplement 1): 2131.
https://doi.org/10.1182/blood-2023-172978
Published: 2023