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Margot Pont
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Journal Articles

Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy

David G Coffey, Pinar Ataca Atilla, Erden Atilla, Ola Landgren, Andrew J Cowan, Sylvain Simon, Margot Pont, Melissa L. Comstock, Geoffrey R Hill, Stanley R. Riddell, Damian J Green
Journal: Blood
Blood blood.2024025231.
https://doi.org/10.1182/blood.2024025231
Published: 2024
Includes: Supplemental data
Journal Articles

Resistance to CD38 Antigen Targeted Therapy in Multiple Myeloma May Result from Underrecognized Chromosome 4 Gene Deletions

Andrew J Portuguese, Min Fang, Sherilyn A. Tuazon, Margot Pont, Xiaoyu Qu, Carolyn Shasha, Melissa L Comstock, Justina Lyons, Gabriel Cole, Evan W. Newell, Emily Glynn, Lorinda Soma, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 1976.
https://doi.org/10.1182/blood-2023-186688
Published: 2023
Journal Articles

Seven-Day Vein-to-Vein Point-of-Care Manufactured CD19 CAR T Cells (GLPG5101) in Relapsed/Refractory NHL: Results from the Phase 1 Atalanta-1 Trial

Marie José Kersten, Kirsten Saevels, Yves Beguin, Joost S.P Vermaat, Nadia Verbruggen, Maike Spoon, Marte C. Liefaard, Margot Pont, Anna D.D. van Muyden, Maria T. Kuipers, Sébastien Anguille
Journal: Blood
Blood (2023) 142 (Supplement 1): 2113.
https://doi.org/10.1182/blood-2023-172736
Published: 2023
Journal Articles

Seven-Day Vein-to-Vein Point-of-Care Manufactured CD19 CAR T Cells (GLPG5201) in Relapsed/Refractory CLL/SLL Including Richter's Transformation: Results from the Phase 1 Euplagia-1 Trial

Natalia Tovar, Valentin Ortiz-Maldonado, Nuria Martinez-Cibrian, Sergi Betriu, Daniel Esteban, Ana Triguero, Nadia Verbruggen, Maike Spoon, Marte C. Liefaard, Margot Pont, Anna D.D. van Muyden
Journal: Blood
Blood (2023) 142 (Supplement 1): 2112.
https://doi.org/10.1182/blood-2023-189321
Published: 2023
Journal Articles

Impact of Gamma-Secretase Inhibition on the Multiple Myeloma Immune Microenvironment

David Coffey, Ola Landgren, Andrew J. Cowan, Pinar Ataca Atilla, Sylvain Simon, Margot Pont, Melissa L Comstock, Geoffrey R Hill, Stanley R. Riddell, Damian J Green
Journal: Blood
Blood (2023) 142 (Supplement 1): 4683.
https://doi.org/10.1182/blood-2023-186980
Published: 2023
Journal Articles

Safety and Efficacy of Fully Human BCMA CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase BCMA Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma

Andrew J. Cowan, Margot Pont, Blythe Duke Sather, Cameron J. Turtle, Brian G. Till, Edward Libby, David G. Coffey, Sherilyn A. Tuazon, Brent L. Wood, Ted A Gooley, Qian Vicky Wu, Mazyar Shadman, Jordan Gauthier, Aude G. Chapuis, Filippo Milano, David G. Maloney, Stanley R. Riddell, Damian J. Green
Journal: Blood
Blood (2021) 138 (Supplement 1): 551.
https://doi.org/10.1182/blood-2021-154170
Published: 2021
Journal Articles

Response to Bcma CAR-T Cells Correlates with Pretreatment Target Antigen Density and Is Improved By Small Molecule Inhibition of Gamma Secretase

Damian J. Green, MD, Margot Pont, PhD, Andrew J. Cowan, MD, Gabriel O Cole, Blythe Duke Sather, PhD, Anne M Nagengast, RN, Xaoling Song, Sushma Thomas, Brent L Wood, MD PhD, Michelle L Blake, PhD, Melissa G Works, PhD, Ted A Gooley, PhD, David G. Maloney, MD PhD, Stanley R. Riddell, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1856.
https://doi.org/10.1182/blood-2019-129582
Published: 2019
Journal Articles

Efficacy and Safety of Fully Human Bcma CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase Bcma Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma

Andrew J. Cowan, MD, Margot Pont, PhD, Blythe Duke Sather, PhD, Cameron J. Turtle, MBBS, PhD, Brian G. Till, MD, Anne M Nagengast, RN, Edward N. Libby, III, MD, Pamela S. Becker, MD PhD, David G. Coffey, MD, Sherilyn A. Tuazon, MD, Brent L Wood, MD PhD, Michelle L Blake, PhD, Melissa G Works, PhD, Ted A Gooley, PhD, Qian Vicky Wu, PhD, David G. Maloney, MD PhD, Stanley R. Riddell, MD, Damian J. Green, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 204.
https://doi.org/10.1182/blood-2019-129405
Published: 2019
Journal Articles

Fully Human Bcma Targeted Chimeric Antigen Receptor T Cells Administered in a Defined Composition Demonstrate Potency at Low Doses in Advanced Stage High Risk Multiple Myeloma

Damian J. Green, MD, Margot Pont, PhD, Blythe Duke Sather, PhD, Andrew J. Cowan, MD, Cameron J. Turtle, MBBS, PhD, Brian G. Till, MD, Anne M Nagengast, RN, Edward N. Libby, III, MD, Pamela S. Becker, MD, David G. Coffey, MD, Sherilyn A. Tuazon, MD, Brent Wood, MD PhD, Michelle Blake, PhD, Melissa Works, PhD, Bruce S Thompson, PhD, Ted Gooley, PhD, Frederick R. Appelbaum, MD, David G. Maloney, MD PhD, Stanley R. Riddell, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1011.
https://doi.org/10.1182/blood-2018-99-117729
Published: 2018
Journal Articles

Development of JCARH125: Optimization of a Fully Human Anti-Bcma CAR for Use in the Treatment of Multiple Myeloma

Kim Harrington, BS, Rebecca Wu, BS, Collin Hauskins, BS, Rupesh Amin, PhD, Thomas Long, PhD, Aye Chen, BA, Ayu Rahardjo, BS, Casey Thayer, BS, Garnet Navvaro, BS, Madelyn Myers, MS, Jon Jones, BS, Alex Baturevych, BS, Stan Morkowski, PhD, Ruth Salmon, PhD, Christopher J Bond, PhD, Mette Staehr, PhD, Terence J Purdon, MS, Reed Masakayan, MS, Cheng Liu, PhD, Hong Liu, MD PhD, Yiyang Xu, PhD, Pei Wang, PhD, Margot Pont, PhD, Damian J. Green, MD, Renier J. Brentjens, MD PhD, Eric L Smith, MDPhD, Blythe Duke Sather, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1813.
https://doi.org/10.1182/blood.V130.Suppl_1.1813.1813
Published: 2017