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Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney D. DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z. Orlowski, Muzaffar H. Qazilbash, Kapil N. Bhalla, Simona Colla, Hagop M. Kantarjian, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Daisuke Nakada, Jeffrey J. Molldrem, Gheath Alatrash, Andrew Futreal, Elizabeth J. Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 346.
https://doi.org/10.1182/blood-2024-208106
Published: 2024
Journal Articles

Cancer Chemotherapy Accelerates the Loss of Clonal Diversity in Hematopoietic Stem Cells and Promotes the Convergent Evolution of Therapy-Related Clonal Hematopoiesis

Hidetaka Uryu, Koichi Saeki, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne I. Hsu, Carlos E. Bueso-Ramos, Shujuan Chen, Hui Yang, Hagop Kantarjian, Courtney D. DiNardo, Naval Daver, Simona Colla, Irene Ganan-Gomez, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Robert Z. Orlowski, Richard E Champlin, Muzaffar H Qazilbash, Elizabeth J Shpall, Guillermo Garcia-Manero, Hiroshi Haeno, Koichi Takahashi, Andrew Futreal
Journal: Blood
Blood (2022) 140 (Supplement 1): 2232–2233.
https://doi.org/10.1182/blood-2022-160294
Published: 2022
Journal Articles

Comprehensive Analysis of Genotype and Prior Exposures in Therapy-Related Myeloid Neoplasms (t-MNs)

Veronica A Guerra, MD, Yan Yuanqing, PhD, Joanne Hsu, BS, Feng Wang, PhD, Mansour Alfayez, MD, Kiyomi Morita, MD, Xingzhi Song, PhD, Courtney D. DiNardo, MD MSc, Marina Y Konopleva, MD PhD, Gautam M. Borthakur, MD, Guillermo Montalban Bravo, MD, Jianhua Zhang, PhD, Latasha Little, BS, Curtis Gumbs, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 458.
https://doi.org/10.1182/blood-2019-127498
Published: 2019
Journal Articles

Comprehensive Genomic Analysis of IDH Inhibitor-Treated AML Samples Delineates Molecular Mechanisms of Differentiation and Heterogeneous Patterns of Acquired Resistance

Feng Wang, PhD, Kiyomi Morita, MD, Courtney D. DiNardo, MDMSc, Keyur Patel, MD PhD, Kyle MacBeth, PhD, Alessandra Tosolini, BS, Mark G. Frattini, MD, Jairo Matthews, BA, Latasha Little, Curtis Gumbs, Samantha Tippen, Xingzhi Song, PhD, Jianhua Zhang, PhD, Erika Thompson, MS, Tapan M. Kadia, MD, Guillermo Garcia-Manero, MD, Elias J. Jabbour, MD, Farhad Ravandi, MD, Marina Y. Konopleva, MD PhD, Hagop M. Kantarjian, MD, Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 441.
https://doi.org/10.1182/blood-2018-99-116383
Published: 2018
Journal Articles

Pan-Myeloid Leukemia Analysis: Machine Learning-Based Approach to Predict Phenotype and Clinical Outcomes Using Mutation Data

Kiyomi Morita, MD, Feng Wang, PhD, Hideki Makishima, MD PhD, Yuanqing Yan, PhD, Tetsuichi Yoshizato, MD PhD, Kenichi Yoshida, MD PhD, Bartlomiej P. Przychodzen, Keyur Patel, MD PhD, Carlos E. Bueso-Ramos, MD PhD, Curtis Gumbs, Latasha Little, Samantha Tippen, Jianhua Zhang, PhD, Xingzhi Song, PhD, Tapan M. Kadia, MD, Naval G. Daver, MD, Naveen Pemmaraju, MD, Courtney D. DiNardo, MDMSc, Farhad Ravandi, MD, Srdan Verstovsek, MD PhD, Elias J. Jabbour, MD, Jorge E. Cortes, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, Jaroslaw P. Maciejewski, Seishi Ogawa, MD PhD, P Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1801.
https://doi.org/10.1182/blood-2018-99-116685
Published: 2018
Journal Articles

Single-Cell Atlas of Driver Mutations in Acute Myeloid Leukemia (AML)

Kiyomi Morita, MD, Feng Wang, PhD, Robert Durruthy-Durruthy, PhD, Anup Parikh, Jairo Matthews, BA, Latasha Little, Samantha Tippen, Curtis Gumbs, Jianhua Zhang, PhD, Xingzhi Song, PhD, Erika Thompson, MS, Keyur Patel, MD PhD, Carlos E. Bueso-Ramos, MD PhD, Courtney D. DiNardo, MDMSc, Farhad Ravandi, MD, Elias J. Jabbour, MD, Michael Andreeff, MD PhD, Jorge E. Cortes, MD, Marina Y. Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Dennis J. Eastburn, PhD, P Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 88.
https://doi.org/10.1182/blood-2018-99-117358
Published: 2018
Journal Articles

Clinical Heterogeneity of AML Is Associated with Mutational Heterogeneity

Mahesh Swaminathan, MD, Kiyomi Morita, MD, Yan Yuanqing, Feng Wang, PhD, Jared K Burks, PhD, Curtis Gumbs, Latasha Little, Samantha Tippen, Rebecca Thornton, Marcus Coyle, Jianhua Zhang, PhD, Xingzhi Song, PhD, Courtney D. DiNardo, MD MSc, Elias J. Jabbour, MD, Tapan M. Kadia, MD, Jorge E. Cortes, MD, Naval G. Daver, MD, Naveen Pemmaraju, MD, Keyur Patel, MD PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Carlos E. Bueso-Ramos, MD PhD, Andy Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5240.
https://doi.org/10.1182/blood-2018-99-117287
Published: 2018
Journal Articles

Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

Clinical Trials & Observations
Koichi Takahashi, Boyu Hu, Feng Wang, Yuanqing Yan, Ekaterina Kim, Candida Vitale, Keyur P. Patel, Paolo Strati, Curtis Gumbs, Latasha Little, Samantha Tippen, Xingzhi Song, Jianhua Zhang, Nitin Jain, Philip Thompson, Guillermo Garcia-Manero, Hagop Kantarjian, Zeev Estrov, Kim-Anh Do, Michael Keating, Jan A. Burger, William G. Wierda, P. Andrew Futreal, Alessandra Ferrajoli
Journal: Blood
Blood (2018) 131 (16): 1820–1832.
https://doi.org/10.1182/blood-2017-11-817296
Published: 2018
Includes: Supplemental data
Journal Articles

Persistent Somatic Mutation at Remission Is Associated with Poor Survival and Higher Risk of Relapse in Patients with Acute Myeloid Leukemia

Kiyomi Morita, MD, Feng Wang, PhD, Keyur Patel, MD PhD, Carlos Bueso-Ramos, MD PhD, Ghayas C. Issa, MD, Xingzhi Song, Jianhua Zhang, Samantha Tippen, Rebecca Thornton, Marcus Coyle, Latasha Little, Curtis Gumbs, Farhad Ravandi, MBBS, Tapan Kadia, MD, Naval Daver, MD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Jorge E. Cortes, MD, Guillermo Garcia-Manero, MD, Elias J. Jabbour, MD, Andrew Futreal, PhD, Hagop M. Kantarjian, MD, Koichi Takahashi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2667.
https://doi.org/10.1182/blood.V130.Suppl_1.2667.2667
Published: 2017
Journal Articles

Genome-Wide Chip-Seq Analysis of Histone Methylation Reveals Modulators of NF-κB Signaling and the Histone Demethylase JMJD3 as Implicated in Disease Progression in Myelodysplastic Syndrome (MDS).

Yue Wei, PhD, Rui Chen, PhD, Carlos E. Bueso-Ramos, MD, Hui Wang, PhD, Xingzhi Song, PhD, Jing Wang, Hui Yao, Martin Nguyen, Michael Fernandez, Hui Yang, MD, PhD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2009) 114 (22): 291.
https://doi.org/10.1182/blood.V114.22.291.291
Published: 2009