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Hidetaka Uryu
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Journal Articles

Distinct Impact of Platinum Chemotherapies on the Fitness and Genome of Hematopoietic Stem Cells and the Risk of Therapy-Related Myeloid Neoplasms

Jeremy Connors, Linda Zhang, Hidetaka Uryu, Koji Sasaki, Jennifer Padilla, Zongrui Li, Ken Furudate, Tomoyuki Tanaka, Courtney D. DiNardo, Nicholas J. Short, Naval Daver, Gautham Borthakur, Farhad Ravandi, Tapan M. Kadia, Hagop M. Kantarjian, Elias Jabbour, Simona Colla, Branko Cuglievan, Andrew Futreal, Adam S. Sperling, Guillermo Garcia-Manero, Margaret Goodell, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1816.
https://doi.org/10.1182/blood-2024-212052
Published: 2024
Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney D. DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z. Orlowski, Muzaffar H. Qazilbash, Kapil N. Bhalla, Simona Colla, Hagop M. Kantarjian, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Daisuke Nakada, Jeffrey J. Molldrem, Gheath Alatrash, Andrew Futreal, Elizabeth J. Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 346.
https://doi.org/10.1182/blood-2024-208106
Published: 2024
Journal Articles

Mutant Natural Killer Cell Dysfunction Enables the Immune Escape of Premalignant MDS Cell Clones

Irene Ganan-Gomez, Bijender Kumar, Juan Jose Rodriguez Sevilla, Feiyang Ma, Yi June Kim, Kelly S. Chien, Kate Nelson, Hui Yang, Roselyn Tan, Zongrui Li, Tomoyuki Tanaka, Hidetaka Uryu, Rashmi Kanagal-Shamanna, Sanam Loghavi, Gheath Alatrash, Rafael Bejar, Katayoun Rezvani, Koichi Takahashi, Guillermo Garcia-Manero, May Daher, MD, Simona Colla
Journal: Blood
Blood (2023) 142 (Supplement 1): 514.
https://doi.org/10.1182/blood-2023-184349
Published: 2023
Journal Articles

Single-Cell Proteogenomics Analysis of AML Samples Treated with Decitabine and Venetoclax Reveals Divergent Treatment Escape Mechanisms

Yi June Kim, Zongrui Li, Abhishek Maiti, Tomoyuki Tanaka, Hidetaka Uryu, Ken Furudate, Kala Hayes, Naval Daver, Naveen Pemmaraju, Tapan M. Kadia, Farhad Ravandi, Nicholas J. Short, Maro Ohanian, Gautam Borthakur, Nitin Jain, Ghayas C. Issa, Lucia Masarova, Steven M. Kornblau, William G. Wierda, Sanam Loghavi, Sa A. Wang, Guillermo Garcia-Manero, Hagop Kantarjian, Courtney D. DiNardo, Marina Y. Konopleva, Koichi Takahashi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2931.
https://doi.org/10.1182/blood-2023-190400
Published: 2023
Journal Articles

Cancer Chemotherapy Accelerates the Loss of Clonal Diversity in Hematopoietic Stem Cells and Promotes the Convergent Evolution of Therapy-Related Clonal Hematopoiesis

Hidetaka Uryu, Koichi Saeki, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne I. Hsu, Carlos E. Bueso-Ramos, Shujuan Chen, Hui Yang, Hagop Kantarjian, Courtney D. DiNardo, Naval Daver, Simona Colla, Irene Ganan-Gomez, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Robert Z. Orlowski, Richard E Champlin, Muzaffar H Qazilbash, Elizabeth J Shpall, Guillermo Garcia-Manero, Hiroshi Haeno, Koichi Takahashi, Andrew Futreal
Journal: Blood
Blood (2022) 140 (Supplement 1): 2232–2233.
https://doi.org/10.1182/blood-2022-160294
Published: 2022
Journal Articles

Genome-Wide CRISPR Screen Reveals Dependency of PPM1D- mutant Cells on DNA Repair

Linda Zhang, Joanne I. Hsu, Etienne D. Braekeleer, Hidetaka Uryu, Elsa Callen-Moreu, Andre Nussenzweig, Koichi Takahashi, George S Vassiliou, Margaret A. Goodell
Journal: Blood
Blood (2022) 140 (Supplement 1): 1994–1995.
https://doi.org/10.1182/blood-2022-166910
Published: 2022
Journal Articles

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

Hidetaka Uryu, Daigo Hashimoto, Koji Kato, Eiko Hayase, Satomi Matsuoka, Reiki Ogasawara, Shuichiro Takahashi, Yoshinobu Maeda, Hiromi Iwasaki, Toshihiro Miyamoto, Shinobu Saijo, Yoichiro Iwakura, Geoffrey R. Hill, Koichi Akashi, Takanori Teshima
Journal: Blood
Blood (2015) 125 (19): 3014–3023.
https://doi.org/10.1182/blood-2014-12-615781
Published: 2015
Includes: Supplemental data
Journal Articles

Graft-Versus-Host Disease Targets Ovary and Causes Infertility After Allogeneic Hematopoietic Stem Cell Transplantation

Sonoko Shimoji, MD, Koji Kato, MD, PhD, Hidetsugu Tsujigiwa, PhD, Yoshihiro Eriguchi, MD, PhD, Lifa Lee, MD, Hidetaka Uryu, MD, Shuichiro Takashima, MD, PhD, Daigo Hashimoto, MD, PhD, Koichi Akashi, MD, PhD, Takanori Teshima, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4470.
https://doi.org/10.1182/blood.V122.21.4470.4470
Published: 2013
Journal Articles

Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins

Yoshihiro Eriguchi, Shuichiro Takashima, Hideyo Oka, Sonoko Shimoji, Kiminori Nakamura, Hidetaka Uryu, Shinji Shimoda, Hiromi Iwasaki, Nobuyuki Shimono, Tokiyoshi Ayabe, Koichi Akashi, Takanori Teshima
Journal: Blood
Blood (2012) 120 (1): 223–231.
https://doi.org/10.1182/blood-2011-12-401166
Published: 2012
Journal Articles

Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17

Hisakazu Nishimori, Yoshinobu Maeda, Takanori Teshima, Haruko Sugiyama, Koichiro Kobayashi, Yoshiko Yamasuji, Sachiyo Kadohisa, Hidetaka Uryu, Kengo Takeuchi, Takehiro Tanaka, Tadashi Yoshino, Yoichiro Iwakura, Mitsune Tanimoto
Journal: Blood
Blood (2012) 119 (1): 285–295.
https://doi.org/10.1182/blood-2011-01-332478
Published: 2012
Includes: Supplemental data