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Journal Articles

Combined Targeting Patient-Specific Anti-Apoptotic Molecules and CXCR4-Expressing CAR-T Cells Eliminated High-Inflammation State Leukemia with Poor-Prognostic Mutations

Blood (2024) 144 (Supplement 1): 1453.

https://doi.org/10.1182/blood-2024-204989

Published: 2024

Journal Articles

Identification of Patient-Specific Anti-Apoptotic Molecules As Therapeutic Targets in Poor Prognosis Acute Lymphoblastic Leukemia (ALL)

Ryo Nakagawa, Yoriko Saito, Shinsuke Takagi, Sadaaki Takata, Hanae Amitani, Mikiko Endo, Naoyuki Uchida, Yukihide Momozawa, Shuichi Taniguchi, Hideo Harigae, Fumihiko Ishikawa

Blood (2021) 138 (Supplement 1): 1236.

https://doi.org/10.1182/blood-2021-147625

Published: 2021

Journal Articles

CXCR4-Expressing Anti-CD25 CAR T-Cells Effectively Eliminate Human AML Cells In Vivo

Ari Itoh-Nakadai, PhD, Yoriko Saito, MD, Mariko Murasawa-Tomizawa, Hiroshi Kajita, Takehisa Matsumoto, PhD, Masashi Matsuda, PhD, Takashi Watanabe, PhD, Mikako Shirouzu, Osamu Ohara, PhD, Haruhiko Koseki, MD PhD, Leonard Shultz, PhD, Fumihiko Ishikawa, MDPhD

Blood (2020) 136 (Supplement 1): 35–36.

https://doi.org/10.1182/blood-2020-142228

Published: 2020

Journal Articles

Targeting Critical Kinases and Anti-Apoptotic Molecules Overcomes Steroid Resistance in Infant MLL-Rearranged Leukemia

Anne Pieta De Groot, Yoriko Saito, MD, Eiryo Kawakami, Mari Hashimoto, Yuki Aoki, Rintaro Ono, MD PhD, Ikuko Ogahara, Saera Fujiki, Akiko Kaneko, Takashi Watanabe, PhD, Masatoshi Takagi, MD PhD, Daisuke Tomizawa, MD PhD, Katsuyoshi Koh, MD, Mariko Eguchi, MD, Eiichi Ishii, MD PhD, Osamu Ohara, Leonard Shultz, PhD, Shuki Mizutani, Fumihiko Ishikawa, MD PhD

Blood (2019) 134 (Supplement_1): 3885.

https://doi.org/10.1182/blood-2019-129719

Published: 2019

Journal Articles

Induction of WT1-specific human CD8 + T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice

Yuho Najima, Mariko Tomizawa-Murasawa, Yoriko Saito, Takashi Watanabe, Rintaro Ono, Toshiki Ochi, Nahoko Suzuki, Hiroshi Fujiwara, Osamu Ohara, Leonard D. Shultz, Masaki Yasukawa, Fumihiko Ishikawa

Blood (2016) 127 (6): 722–734.

https://doi.org/10.1182/blood-2014-10-604777

Published: 2016

Includes: Supplemental data

Journal Articles

Identification of CD34 + and CD34 − leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia

Blood (2015) 125 (6): 967–980.

https://doi.org/10.1182/blood-2014-03-563304

Published: 2015

Includes: Supplemental data

Journal Articles

Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation

Shinsuke Takagi, Yoriko Saito, Atsushi Hijikata, Satoshi Tanaka, Takashi Watanabe, Takanori Hasegawa, Shinobu Mochizuki, Jun Kunisawa, Hiroshi Kiyono, Haruhiko Koseki, Osamu Ohara, Takashi Saito, Shuichi Taniguchi, Leonard D. Shultz, Fumihiko Ishikawa

Blood (2012) 119 (12): 2768–2777.

https://doi.org/10.1182/blood-2011-05-353201

Published: 2012

Includes: Supplemental data

Journal Articles

Membrane-Bound Human Stem Cell Factor Promotes Differentiation of Human Granulocytes and Mast Cells In Vivo,

Shinsuke Takagi, MD, Yoriko Saito, MD, Atsushi Hijikata, PhD, Satoshi Tanaka, Takashi Watanabe, PhD, Haruhiko Koseki, MD, PhD, Osamu Ohara, PhD, Takashi Saito, PhD, Shuichi Taniguchi, MD, PhD, Leonard Shultz, PhD, Fumihiko Ishikawa, MD, PhD

Blood (2011) 118 (21): 3419.

https://doi.org/10.1182/blood.V118.21.3419.3419

Published: 2011

Journal Articles

Hematopoietic Stem Cells Are Primarily Involved In Pathogenesis of Chronic Lymphocytic Leukemia.

Yoshikane Kikushige, MD, Fumihiko Ishikawa, MD, PhD, Toshihiro Miyamoto, MD, PhD, Koichi Akashi, MD., PhD.

Blood (2010) 116 (21): 4604.

https://doi.org/10.1182/blood.V116.21.4604.4604

Published: 2010

Journal Articles

Development of Novel Stem Cell Transplantation and Gene-Immunotherapy Using WT1-Specific T-Cell Receptor Gene.

Toshiki Ochi, MD, Hiroshi Fujiwara, MD, PhD, Kozo Nagai, MD, Toshiaki Shirakata, MD, PhD, Kiyotaka Kuzushima, MD, PhD, Sachiko Okamoto, PhD, Junichi Mineno, PhD, Hiroshi Shiku, MD, PhD, Hidetoshi Ozawa, PhD, Fumihiko Ishikawa, MD, PhD, Masaki Yasukawa, MD, PhD

Blood (2009) 114 (22): 3028.

https://doi.org/10.1182/blood.V114.22.3028.3028

Published: 2009

Journal Articles

Cell Cycle Entry Potentiates Elimination of Chemotherapy-Resistant Human AML Stem Cells.

Yoriko Saito, MD, Naoyuki Uchida, MD, PhD, Satoshi Tanaka, Mariko Tomizawa-Murasawa, Nahoko Suzuki, Shinsuke Takagi, MD, Yuho Najima, MD, Yuki Aoki, MD, Akiko Sone, Atsushi Wake, MD, Shuichi Taniguchi, MD, PhD, Leonard D. Shultz, PhD, Fumihiko Ishikawa, MD, PhD

Blood (2009) 114 (22): 1422.

https://doi.org/10.1182/blood.V114.22.1422.1422

Published: 2009

Journal Articles

Hematopoietic Stem Cells Are Primarily Involved in Pathogenesis of Chronic Lymphocytic Leukemia

YoshiKane KiKushige, MD, Toshihiro Miyamoto, MD, PhD, Tadafumi Iino, MD, Fumihiko Ishikawa, MD, PhD, Koichi Akashi, MD, PhD

Blood (2008) 112 (11): 29.

https://doi.org/10.1182/blood.V112.11.29.29

Published: 2008

Journal Articles

Analysis of Idiopathic Myelofibrosis Initiating Cell in NOD/SCID/IL2rgKO Mice

Noriyuki Saito, MD, Fumihiko Ishikawa, MD, PhD, Kazuya Shimoda, MD, PhD, Shuro Yoshida, MD, PhD, Yoriko Saito, MD, Mitsuhiro Fukata, MD, Chika Iwamoto, Noriaki Kawano, MD, PhD, Leonard Shultz, PhD, Mine Harada, MD, Koichi Akashi, MD, PhD

Blood (2008) 112 (11): 3715.

https://doi.org/10.1182/blood.V112.11.3715.3715

Published: 2008

Journal Articles

Hematopoietic origin of hepatic stellate cells in the adult liver

Eri Miyata, Masahiro Masuya, Shuro Yoshida, Shiho Nakamura, Keizo Kato, Yuka Sugimoto, Tetsunori Shibasaki, Kentaro Yamamura, Kohshi Ohishi, Kazuhiro Nishii, Fumihiko Ishikawa, Hiroshi Shiku, Naoyuki Katayama

Blood (2008) 111 (4): 2427–2435.

https://doi.org/10.1182/blood-2007-07-101261

Published: 2008

Journal Articles

Human FLT3/FLK2 Targets Hematopoietic Stem Cells and Granulocyte/Macrophage Progenitors.

Yoshikane Kikushige, Goichi Yoshimoto, Toshihiro Miyamoto, Fumihiko Ishikawa, Hiromi Iwasaki, Koichi Akashi

Blood (2007) 110 (11): 1263.

https://doi.org/10.1182/blood.V110.11.1263.1263

Published: 2007

Journal Articles

Establishment of Novel Disease Models for Human Acute Type ATL and HTLV-I Carrier Using NOD-scid/IL2rg null Mouse.

Chika Iwamoto, Fumihiko Ishikawa, MD, PhD, Noriaki Kawano, MD, PhD, Noriyuki Saito, MD, Shen M. Yang, MD, PhD, Mitsuhiro Fukata, MD, Yoriko Saito, MD, PhD, Leonard D. Shultz, PhD, Masao Matsuoka, MD, PhD, Mine Harada, MD, PhD

Blood (2007) 110 (11): 2797.

https://doi.org/10.1182/blood.V110.11.2797.2797

Published: 2007

Journal Articles

Transplantation of Primary Human CD34+CD38 - Hematopoietic Stem Cells Recapitulates Idiopathic Myelofibrosis in the NOD/scid/IL2rgKO Mice.

Noriyuki Saito, MD, Fumihiko Ishikawa, MD/PhD, Kazuya Shimoda, MD/PhD, Shuro Yoshida, MD/PhD, Yoriko Saito, MD, Mitsuhiro Fukata, MD, Noriaki Kawano, MD/PhD, Leonard D. Shulz, PhD, Koichi Akashi, MD/PhD, Mine Harada, MD

Blood (2007) 110 (11): 260.

https://doi.org/10.1182/blood.V110.11.260.260

Published: 2007

Journal Articles

Human AML Stem Cells Remain Quiescent and Exhibit Chemotherapy Resistance within the Bone Marrow Endosteal Region.

Yoriko Saito, MD, Shuro Yoshida, MD/PhD, Noriyuki Saito, MD, Mitsuhiro Fukata, MD, Hidetoshi Ozawa, MSc, Takehiko Doi, MD/PhD, Toshihiro Miyamoto, MD/PhD, Koichi Ohshima, MD/PhD, Naoyuki Uchida, MD/PhD, Shuichi Taniguchi, MD/PhD, Koichi Akashi, MD/PhD, Mine Harada, MD, Leonard D. Shultz, PhD, Fumihiko Ishikawa, MD/PhD

Blood (2007) 110 (11): 780.

https://doi.org/10.1182/blood.V110.11.780.780

Published: 2007

Journal Articles

The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways

Fumihiko Ishikawa, Hiroaki Niiro, Tadafumi Iino, Shuro Yoshida, Noriyuki Saito, Shinya Onohara, Toshihiro Miyamoto, Hiroko Minagawa, Shin-ichiro Fujii, Leonard D. Shultz, Mine Harada, Koichi Akashi

Blood (2007) 110 (10): 3591–3660.

https://doi.org/10.1182/blood-2007-02-071613

Published: 2007

Journal Articles

Hematopoietic Origin of Hepatic Stellate Cell.

Eri Miyata, MD, Masahiro Masuya, MD, Fumihiko Ishikawa, MD, Shuro Yoshida, MD, Keizo Kato, MD, Kohshi Ohishi, MD, Naoyuki Katayama, MD

Blood (2006) 108 (11): 1679.

https://doi.org/10.1182/blood.V108.11.1679.1679

Published: 2006

NARROW

Combined Targeting Patient-Specific Anti-Apoptotic Molecules and CXCR4-Expressing CAR-T Cells Eliminated High-Inflammation State Leukemia with Poor-Prognostic Mutations

Identification of Patient-Specific Anti-Apoptotic Molecules As Therapeutic Targets in Poor Prognosis Acute Lymphoblastic Leukemia (ALL)

CXCR4-Expressing Anti-CD25 CAR T-Cells Effectively Eliminate Human AML Cells In Vivo

Targeting Critical Kinases and Anti-Apoptotic Molecules Overcomes Steroid Resistance in Infant MLL-Rearranged Leukemia

Induction of WT1-specific human CD8 + T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice

Identification of CD34 + and CD34 − leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia

Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation

Membrane-Bound Human Stem Cell Factor Promotes Differentiation of Human Granulocytes and Mast Cells In Vivo,

Hematopoietic Stem Cells Are Primarily Involved In Pathogenesis of Chronic Lymphocytic Leukemia.

Development of Novel Stem Cell Transplantation and Gene-Immunotherapy Using WT1-Specific T-Cell Receptor Gene.

Cell Cycle Entry Potentiates Elimination of Chemotherapy-Resistant Human AML Stem Cells.

Hematopoietic Stem Cells Are Primarily Involved in Pathogenesis of Chronic Lymphocytic Leukemia

Analysis of Idiopathic Myelofibrosis Initiating Cell in NOD/SCID/IL2rgKO Mice

Hematopoietic origin of hepatic stellate cells in the adult liver

Human FLT3/FLK2 Targets Hematopoietic Stem Cells and Granulocyte/Macrophage Progenitors.

Establishment of Novel Disease Models for Human Acute Type ATL and HTLV-I Carrier Using NOD-scid/IL2rg null Mouse.

Transplantation of Primary Human CD34+CD38 - Hematopoietic Stem Cells Recapitulates Idiopathic Myelofibrosis in the NOD/scid/IL2rgKO Mice.

Human AML Stem Cells Remain Quiescent and Exhibit Chemotherapy Resistance within the Bone Marrow Endosteal Region.

The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways

Hematopoietic Origin of Hepatic Stellate Cell.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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