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Niklas Feldhahn
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Journal Articles

The Transcriptional Landscape of Ph+B-ALL Is Orchestrated By Long-Range Enhancer-Promoter Interactions and the Coordinated Action of Phosphorylation-Dependent and Phosphorylation-Independent Transcription Factors

Han Leng Ng, Mark E Robinson, Valeria Malysheva, Ozgen Deniz, Nicholas Crump, Kadriye Nehir Cosgun, Kaiyue Helian, Mikhail Spivakov, Markus Müschen, Niklas Feldhahn
Journal: Blood
Blood (2023) 142 (Supplement 1): 2779.
https://doi.org/10.1182/blood-2023-173435
Published: 2023
Journal Articles

Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies

Kadriye Nehir Cosgun, Mark E Robinson, Salim Oulghazi, Liang Xu, Gang Xiao, Lai N Chan, Jaewoong Lee, Kohei Kume, Etienne Leveille, David Fonseca Arce, Dhruv Khanduja, Niklas Feldhahn, Joo Y. Song, Wing C. Chan, Jianjun Chen, M. Mark Taketo, Hilde Schjerven, Julia Jellusova, Shalin Kothari, Matthew S Davids, Markus Müschen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2818.
https://doi.org/10.1182/blood-2023-190522
Published: 2023
Journal Articles

Oncogenic MAF in Co-Operation with IRF4 Confers Extensive Chromatin Re-Arrangement in Plasma Cells and Generates 'Neo-Enhancers' That Regulate Genes Critical for Myeloma Biology

Alexia Katsarou, Nikolaos Trasanidis, Jaime Alvarez-Benayas, Foteini Papaleonidopoulou, Keren Keren, Ioannis V. Kostopoulos, Kanagaraju Ponnusamy, Xiaolin Xiao, Niklas Feldhahn, Irene Roberts, Evdoxia Hatjiharissi, Maria Papaioannou, Ian Sudbery, Aristeidis Chaidos, Valentina S Caputo, Anastasios Karadimitris
Journal: Blood
Blood (2019) 134 (Supplement_1): 3783.
https://doi.org/10.1182/blood-2019-122371
Published: 2019
Journal Articles

The B Cell Mutator AID Promotes B Lymphoid Blast Crisis and Drug-Resistance in Chronic Myeloid Leukemia.

Lars Klemm, Cihangir Duy, Ilaria Iacobucci, PhD, Gregor von Levetzow, Niklas Feldhahn, Yong-mi Kim, Wolf-Karsten Hofmann, Hassan Jumaa, John Groffen, Nora Heisterkamp, Giovanni Martinelli, MD, Michael R Lieber, Rafael Casellas, Markus Müschen
Journal: Blood
Blood (2009) 114 (22): 3274.
https://doi.org/10.1182/blood.V114.22.3274.3274
Published: 2009
Journal Articles

Lymphoid Blast Crisis Transformation and Development of Drug- Resistance in Chronic Myeloid Leukemia Are Driven by Aberrant Somatic Hypermutation

Lars Klemm, Cihangir Duy, Niklas Feldhahn, John Groffen, Yong-mi Kim, Wolf-Karsten Hofmann, MD, Hassan Jumaa, Michael R Lieber, Rafael Casellas, Markus Muschen
Journal: Blood
Blood (2008) 112 (11): 571.
https://doi.org/10.1182/blood.V112.11.571.571
Published: 2008
Journal Articles

PAX5 -Mediated Lineage Conversion and Expression of AID Accelerates Clonal Evolution and Initiates Darwinian Selection of BCR-ABL1 -Mutants in Chronic Myeloid Leukemia.

Lars Klemm, Niklas Feldhahn, PhD, Thomas K. Hoffmann, MD, Wolf-Karsten Hofmann, MD, Hassan Jumaa, PhD, Markus Muschen, MD
Journal: Blood
Blood (2007) 110 (11): 1005.
https://doi.org/10.1182/blood.V110.11.1005.1005
Published: 2007
Journal Articles

Activation-Induced Cytidine Deaminase Acts as a Mutator in BCR-ABL1 -Transformed Acute Lymphoblastic Leukemia Cells.

Niklas Feldhahn, PhD, Florian Klein, MD, Wolf-Karsten Hofmann, MD, Janet D. Rowley, MD, Hassan Jumaa, PhD, Markus Müschen, MD
Journal: Blood
Blood (2006) 108 (11): 640.
https://doi.org/10.1182/blood.V108.11.640.640
Published: 2006
Journal Articles

The BCR-ABL1 Kinase Interferes with Pre-B Cell Receptor Signal Transduction in B Cell Precursor Leukemia Cells.

Florian Klein, Niklas Feldhahn, Peter Wernet, MD, Markus Müschen, MD
Journal: Blood
Blood (2004) 104 (11): 1894.
https://doi.org/10.1182/blood.V104.11.1894.1894
Published: 2004
Journal Articles

Tracing the Pre-B to Immature B Cell Transition in Human Leukemia Cells Reveals a Coordinated Sequence of Primary and Secondary IGK Gene Rearrangement, IGK Deletion and IGL Gene Rearrangement.

Florian Klein, Niklas Feldhahn, Jana L. Mooster, Peter Wernet, MD, Markus Müschen, MD
Journal: Blood
Blood (2004) 104 (11): 315.
https://doi.org/10.1182/blood.V104.11.315.315
Published: 2004