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Rafael Casellas
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Journal Articles

Epigenetic silencing of miR-125b is required for normal B-cell development

Free
Guideng Li, Alex Yick-Lun So, Reeshelle Sookram, Stephanie Wong, Jessica K. Wang, Yong Ouyang, Peng He, Yapeng Su, Rafael Casellas, David Baltimore
Journal: Blood
Blood (2018) 131 (17): 1920–1930.
https://doi.org/10.1182/blood-2018-01-824540
Published: 2018
Includes: Supplemental data
Journal Articles

Regulation and Impact of Chromatin Decondensation in Mammalian Cells

Free
Rafael Casellas, PhD
Journal: Blood
Blood (2016) 128 (22): SCI-51.
https://doi.org/10.1182/blood.V128.22.SCI-51.SCI-51
Published: 2016
Journal Articles

Exposure to Inflammatory Immune Responses As Driver of Clonal Evolution in Childhood Acute Lymphoblastic Leukemia

Free
Lars Klemm, BSc, MSc, Srividya Swaminathan, DPhil, Elli Papaemmanuil, PhD, Anthony M Ford, Mel Greaves, Rafael Casellas, David Schatz, Michael R. Lieber, MDPhD, Markus Muschen, MD PhD
Journal: Blood
Blood (2015) 126 (23): 166.
https://doi.org/10.1182/blood.V126.23.166.166
Published: 2015
Journal Articles

Mechanisms of Clonal Evolution of Pre-Leukemic Clones in Childhood Pre-B Acute Lymphoblastic Leukemia

Free
Srividya Swaminathan, PhD, Lars Klemm, Eugene Park, Anthony M Ford, PhD, Soo-mi Kweon, PhD, Daniel Trageser, Brian Hasselfeld, Nadine Henke, Huimin Geng, PhD, Klaus Schwarz, MD, Rafael Casellas, David G. Schatz, PhD, Michael R Lieber, MD PhD, Elli Papaemmanuil, PhD, Mel Greaves, PhD, Markus Muschen, MD PhD
Journal: Blood
Blood (2014) 124 (21): 861.
https://doi.org/10.1182/blood.V124.21.861.861
Published: 2014
Journal Articles

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3

Free
Scott M. Steward-Tharp, Arian Laurence, Yuka Kanno, Alex Kotlyar, Alejandro V. Villarino, Giuseppe Sciume, Stefan Kuchen, Wolfgang Resch, Elizabeth A. Wohlfert, Kan Jiang, Kiyoshi Hirahara, Golnaz Vahedi, Hong-wei Sun, Lionel Feigenbaum, Joshua D. Milner, Steven M. Holland, Rafael Casellas, Fiona Powrie, John J. O'Shea
Journal: Blood
Blood (2014) 123 (19): 2978–2987.
https://doi.org/10.1182/blood-2013-09-523167
Published: 2014
Includes: Supplemental data
Journal Articles

Cooperation Between Aid and the Rag1/Rag2 V(D)J Recombinase Drives Clonal Evolution of Childhood Acute Lymphoblastic Leukemia

Free
Srividya Swaminathan, B Tech, Lars Klemm, MSc, Anthony M. Ford, PhD, Klaus Schwarz, MD, Rafael Casellas, Lothar Hennighausen, Huimin Geng, PhD, David G. Schatz, Michael R. Lieber, MD, PhD, Mel Greaves, MD, PhD, Markus Muschen, MD
Journal: Blood
Blood (2012) 120 (21): 519.
https://doi.org/10.1182/blood.V120.21.519.519
Published: 2012
Journal Articles

The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development

Free
Masaya Baba, Jonathan R. Keller, Hong-Wei Sun, Wolfgang Resch, Stefan Kuchen, Hyung Chan Suh, Hisashi Hasumi, Yukiko Hasumi, Kyong-Rim Kieffer-Kwon, Carme Gallego Gonzalez, Robert M. Hughes, Mara E. Klein, Hyoungbin F. Oh, Paul Bible, Eileen Southon, Lino Tessarollo, Laura S. Schmidt, W. Marston Linehan, Rafael Casellas
Journal: Blood
Blood (2012) 120 (6): 1254–1261.
https://doi.org/10.1182/blood-2012-02-410407
Published: 2012
Includes: Supplemental data
Journal Articles

IL7Rα Signaling Prevents Premature Expression of AID In Human Pre-B Cells: Implications for Clonal Evolution of Childhood Leukemia

Free
Srividya Swaminathan, Lars Klemm, Soo-mi Kweon, Anthony Ford, Klaus Schwarz, Rafael Casellas, Lothar Hennighausen, David G. Schatz, Michael R. Lieber, Mel F. Greaves, Markus Muschen
Journal: Blood
Blood (2010) 116 (21): 26.
https://doi.org/10.1182/blood.V116.21.26.26
Published: 2010
Journal Articles

The B Cell Mutator AID Promotes B Lymphoid Blast Crisis and Drug-Resistance in Chronic Myeloid Leukemia.

Free
Lars Klemm, Cihangir Duy, Ilaria Iacobucci, PhD, Gregor von Levetzow, Niklas Feldhahn, Yong-mi Kim, Wolf-Karsten Hofmann, Hassan Jumaa, John Groffen, Nora Heisterkamp, Giovanni Martinelli, MD, Michael R Lieber, Rafael Casellas, Markus Müschen
Journal: Blood
Blood (2009) 114 (22): 3274.
https://doi.org/10.1182/blood.V114.22.3274.3274
Published: 2009
Journal Articles

Lymphoid Blast Crisis Transformation and Development of Drug- Resistance in Chronic Myeloid Leukemia Are Driven by Aberrant Somatic Hypermutation

Free
Lars Klemm, Cihangir Duy, Niklas Feldhahn, John Groffen, Yong-mi Kim, Wolf-Karsten Hofmann, MD, Hassan Jumaa, Michael R Lieber, Rafael Casellas, Markus Muschen
Journal: Blood
Blood (2008) 112 (11): 571.
https://doi.org/10.1182/blood.V112.11.571.571
Published: 2008
Journal Articles

Tissue Origin of Igh/Myc Chromosomal Translocations in An Accelerated Pristane-Induced Plasma Cell Tumor Model using BALB/C-Bcl-Xl Transgenic Mice and the Inhibitory Effects of Defective Genes Governing Class Switch recombination in Ung and Aicda Knockout Mice.

Free
Alexander L Kovalchuk, Rafael Casellas, Wendy duBois, Helena Tolarova, Petr F Hausner, Elizabeth Mushinski, Patrick J Nelson, Herbert Morse, III, Michael Potter
Journal: Blood
Blood (2008) 112 (11): 2051.
https://doi.org/10.1182/blood.V112.11.2051.2051
Published: 2008