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Journal Articles

Galectin-3 Inhibition As a Novel Therapeutic Approach in Acute Lymphoblastic Leukemia (ALL)

Somayeh Samadzadeh Tarighat, PhD, Fei Fei, Khuchtumur Bum-Erdene, Helen Blanchard, John Groffen, Nora Heisterkamp, PhD
Journal: Blood
Blood (2015) 126 (23): 2047.
https://doi.org/10.1182/blood.V126.23.2047.2047
Published: 2015
Journal Articles

Role of Survivin in Drug Resistant B-Cell Acute Lymphoblastic Leukemia.

Eugene Park, Enzi Jiang, MD, PhD, Gregor von Levetzow, Cihangir Duy, Lars Klemm, Yao-Te Hsieh, Asha Kadavallore, Hong Ma, PhD, Yi Zhao, MD, Cu Nguyen, John Groffen, PhD, Nora Heisterkamp, PhD, Markus Muschen, MD, Michael Kahn, PhD, Yong-Mi Kim, MD
Journal: Blood
Blood (2009) 114 (22): 10.
https://doi.org/10.1182/blood.V114.22.10.10
Published: 2009
Journal Articles

Targeting Survivin Using ICG-001 May Overcome Drug Resistance in Primary B-Cell Acute Lymphoblastic Leukemia.

Enzi Jiang, MD, PhD, Eugene Park, Carlton Scharman, Yao-Te Hsieh, Asha Kadavallore, Cu Nguyen, Yi Zhao, MD, Michael McMillan, PhD, John Groffen, PhD, Nora Heisterkamp, PhD, Markus Muschen, MD, Michael Kahn, PhD, Yong-Mi Kim, MD
Journal: Blood
Blood (2009) 114 (22): 3072.
https://doi.org/10.1182/blood.V114.22.3072.3072
Published: 2009
Journal Articles

The B Cell Mutator AID Promotes B Lymphoid Blast Crisis and Drug-Resistance in Chronic Myeloid Leukemia.

Lars Klemm, Cihangir Duy, Ilaria Iacobucci, PhD, Gregor von Levetzow, Niklas Feldhahn, Yong-mi Kim, Wolf-Karsten Hofmann, Hassan Jumaa, John Groffen, Nora Heisterkamp, Giovanni Martinelli, MD, Michael R Lieber, Rafael Casellas, Markus Müschen
Journal: Blood
Blood (2009) 114 (22): 3274.
https://doi.org/10.1182/blood.V114.22.3274.3274
Published: 2009
Journal Articles

Preclinical Evaluation of Adjuvant Therapy with AMD3100 for Drug Resistant Philadelphia Chromosome Positive and Negative ALL

Enzi Jiang, MD, PhD, Min Yu, MD, PhD, Yao-Te Hsieh, Brian DeLaTorre, Asha Kadavallore, Carlton Scharman, Eugene Park, Allen S. Yang, MD, PhD, Markus Muschen, MD, John Groffen, PhD, Nora Heisterkamp, PhD, Yong-Mi Kim, MD
Journal: Blood
Blood (2008) 112 (11): 2922.
https://doi.org/10.1182/blood.V112.11.2922.2922
Published: 2008
Journal Articles

Lymphoid Blast Crisis Transformation and Development of Drug- Resistance in Chronic Myeloid Leukemia Are Driven by Aberrant Somatic Hypermutation

Lars Klemm, Cihangir Duy, Niklas Feldhahn, John Groffen, Yong-mi Kim, Wolf-Karsten Hofmann, MD, Hassan Jumaa, Michael R Lieber, Rafael Casellas, Markus Muschen
Journal: Blood
Blood (2008) 112 (11): 571.
https://doi.org/10.1182/blood.V112.11.571.571
Published: 2008
Journal Articles

Pre-B Cell Receptor Signaling Prevents Leukemic Transformation by BCR-ABL1

Daniel Trageser, Cihangir Duy, Lars Klemm, Tanja Gruber, Rahul Nahar, Eugene Park, Yong-mi Kim, John Groffen, Nora Heisterkamp, Wolf-Karsten Hofmann, MD, Giovanni Martinelli, Richard T Williams, MD, PhD, Hassan Jumaa, Markus Muschen
Journal: Blood
Blood (2008) 112 (11): 15.
https://doi.org/10.1182/blood.V112.11.15.15
Published: 2008
Journal Articles

Pre-B Cell Receptor Signaling Prevents Leukemic Transformation by BCR-ABL1 .

Daniel Trageser, Lars Klemm, Sebastian Herzog, Yong-mi Kim, MD, Cihangir Duy, Wolf-Karsten Hofmann, MD, John Groffen, PhD, Nora Heisterkamp, PhD, Hassan Jumaa, PhD, Markus Muschen, MD
Journal: Blood
Blood (2007) 110 (11): 2795.
https://doi.org/10.1182/blood.V110.11.2795.2795
Published: 2007
Journal Articles

Resistance to farnesyltransferase inhibitors in Bcr/Abl-positive lymphoblastic leukemia by increased expression of a novel ABC transporter homolog ATP11a

Bin Zhang, John Groffen, Nora Heisterkamp
Journal: Blood
Blood (2005) 106 (4): 1355–1361.
https://doi.org/10.1182/blood-2004-09-3655
Published: 2005
Journal Articles

Treatment of Bcr/Abl-positive acute lymphoblastic leukemia in P190 transgenic mice with the farnesyl transferase inhibitor SCH66336

Anja Reichert, Nora Heisterkamp, George Q. Daley, John Groffen
Journal: Blood
Blood (2001) 97 (5): 1399–1403.
https://doi.org/10.1182/blood.V97.5.1399
Published: 2001
Journal Articles

Reduced oncogenicity of p190 Bcr/Abl F-actin–binding domain mutants

Nora Heisterkamp, Jan Willem Voncken, Dinithi Senadheera, Ignacio Gonzalez-Gomez, Anja Reichert, Leena Haataja, Arja Reinikainen, Paul K. Pattengale, John Groffen
Journal: Blood
Blood (2000) 96 (6): 2226–2232.
https://doi.org/10.1182/blood.V96.6.2226
Published: 2000
Journal Articles

Quantitative measure of c-abl and p15 methylation in chronic myelogenous leukemia: biological implications

Brief Report
TuDung T. Nguyen, Ann F. Mohrbacher, Yvonne C. Tsai, John Groffen, Nora Heisterkamp, Peter W. Nichols, Mimi C. Yu, Michael Lübbert, Peter A. Jones
Journal: Blood
Blood (2000) 95 (9): 2990–2992.
https://doi.org/10.1182/blood.V95.9.2990.009k08_2990_2992
Published: 2000