1-12 of 12
John Groffen
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Galectin-3 Inhibition As a Novel Therapeutic Approach in Acute Lymphoblastic Leukemia (ALL)

Somayeh Samadzadeh Tarighat, PhD, Fei Fei, Khuchtumur Bum-Erdene, Helen Blanchard, John Groffen, Nora Heisterkamp, PhD
Journal: Blood
Blood (2015) 126 (23): 2047.
https://doi.org/10.1182/blood.V126.23.2047.2047
Published: 2015
Journal Articles

Targeting Survivin Using ICG-001 May Overcome Drug Resistance in Primary B-Cell Acute Lymphoblastic Leukemia.

Enzi Jiang, MD, PhD, Eugene Park, Carlton Scharman, Yao-Te Hsieh, Asha Kadavallore, Cu Nguyen, Yi Zhao, MD, Michael McMillan, PhD, John Groffen, PhD, Nora Heisterkamp, PhD, Markus Muschen, MD, Michael Kahn, PhD, Yong-Mi Kim, MD
Journal: Blood
Blood (2009) 114 (22): 3072.
https://doi.org/10.1182/blood.V114.22.3072.3072
Published: 2009
Journal Articles

The B Cell Mutator AID Promotes B Lymphoid Blast Crisis and Drug-Resistance in Chronic Myeloid Leukemia.

Lars Klemm, Cihangir Duy, Ilaria Iacobucci, PhD, Gregor von Levetzow, Niklas Feldhahn, Yong-mi Kim, Wolf-Karsten Hofmann, Hassan Jumaa, John Groffen, Nora Heisterkamp, Giovanni Martinelli, MD, Michael R Lieber, Rafael Casellas, Markus Müschen
Journal: Blood
Blood (2009) 114 (22): 3274.
https://doi.org/10.1182/blood.V114.22.3274.3274
Published: 2009
Journal Articles

Role of Survivin in Drug Resistant B-Cell Acute Lymphoblastic Leukemia.

Eugene Park, Enzi Jiang, MD, PhD, Gregor von Levetzow, Cihangir Duy, Lars Klemm, Yao-Te Hsieh, Asha Kadavallore, Hong Ma, PhD, Yi Zhao, MD, Cu Nguyen, John Groffen, PhD, Nora Heisterkamp, PhD, Markus Muschen, MD, Michael Kahn, PhD, Yong-Mi Kim, MD
Journal: Blood
Blood (2009) 114 (22): 10.
https://doi.org/10.1182/blood.V114.22.10.10
Published: 2009
Journal Articles

Preclinical Evaluation of Adjuvant Therapy with AMD3100 for Drug Resistant Philadelphia Chromosome Positive and Negative ALL

Enzi Jiang, MD, PhD, Min Yu, MD, PhD, Yao-Te Hsieh, Brian DeLaTorre, Asha Kadavallore, Carlton Scharman, Eugene Park, Allen S. Yang, MD, PhD, Markus Muschen, MD, John Groffen, PhD, Nora Heisterkamp, PhD, Yong-Mi Kim, MD
Journal: Blood
Blood (2008) 112 (11): 2922.
https://doi.org/10.1182/blood.V112.11.2922.2922
Published: 2008
Journal Articles

Lymphoid Blast Crisis Transformation and Development of Drug- Resistance in Chronic Myeloid Leukemia Are Driven by Aberrant Somatic Hypermutation

Lars Klemm, Cihangir Duy, Niklas Feldhahn, John Groffen, Yong-mi Kim, Wolf-Karsten Hofmann, MD, Hassan Jumaa, Michael R Lieber, Rafael Casellas, Markus Muschen
Journal: Blood
Blood (2008) 112 (11): 571.
https://doi.org/10.1182/blood.V112.11.571.571
Published: 2008
Journal Articles

Pre-B Cell Receptor Signaling Prevents Leukemic Transformation by BCR-ABL1

Daniel Trageser, Cihangir Duy, Lars Klemm, Tanja Gruber, Rahul Nahar, Eugene Park, Yong-mi Kim, John Groffen, Nora Heisterkamp, Wolf-Karsten Hofmann, MD, Giovanni Martinelli, Richard T Williams, MD, PhD, Hassan Jumaa, Markus Muschen
Journal: Blood
Blood (2008) 112 (11): 15.
https://doi.org/10.1182/blood.V112.11.15.15
Published: 2008
Journal Articles

Pre-B Cell Receptor Signaling Prevents Leukemic Transformation by BCR-ABL1 .

Daniel Trageser, Lars Klemm, Sebastian Herzog, Yong-mi Kim, MD, Cihangir Duy, Wolf-Karsten Hofmann, MD, John Groffen, PhD, Nora Heisterkamp, PhD, Hassan Jumaa, PhD, Markus Muschen, MD
Journal: Blood
Blood (2007) 110 (11): 2795.
https://doi.org/10.1182/blood.V110.11.2795.2795
Published: 2007
Journal Articles

Resistance to farnesyltransferase inhibitors in Bcr/Abl-positive lymphoblastic leukemia by increased expression of a novel ABC transporter homolog ATP11a

Bin Zhang, John Groffen, Nora Heisterkamp
Journal: Blood
Blood (2005) 106 (4): 1355–1361.
https://doi.org/10.1182/blood-2004-09-3655
Published: 2005
Journal Articles

Treatment of Bcr/Abl-positive acute lymphoblastic leukemia in P190 transgenic mice with the farnesyl transferase inhibitor SCH66336

Anja Reichert, Nora Heisterkamp, George Q. Daley, John Groffen
Journal: Blood
Blood (2001) 97 (5): 1399–1403.
https://doi.org/10.1182/blood.V97.5.1399
Published: 2001
Journal Articles

Reduced oncogenicity of p190 Bcr/Abl F-actin–binding domain mutants

Nora Heisterkamp, Jan Willem Voncken, Dinithi Senadheera, Ignacio Gonzalez-Gomez, Anja Reichert, Leena Haataja, Arja Reinikainen, Paul K. Pattengale, John Groffen
Journal: Blood
Blood (2000) 96 (6): 2226–2232.
https://doi.org/10.1182/blood.V96.6.2226
Published: 2000
Journal Articles

Quantitative measure of c-abl and p15 methylation in chronic myelogenous leukemia: biological implications

Brief Report
TuDung T. Nguyen, Ann F. Mohrbacher, Yvonne C. Tsai, John Groffen, Nora Heisterkamp, Peter W. Nichols, Mimi C. Yu, Michael Lübbert, Peter A. Jones
Journal: Blood
Blood (2000) 95 (9): 2990–2992.
https://doi.org/10.1182/blood.V95.9.2990.009k08_2990_2992
Published: 2000