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Journal Articles

Chemical Modulation of ELF1 Binding to RUNX1 Target Genes Leads to Increased Hematopoietic Stem Cell Self-Renewal

Anne L. Robertson, Lu Yue, Avik Choudhuri, Caroline Kubaczka, Samuel J. Wattrus, Joseph Mandelbaum, Serine Avagyan, Song Yang, Rebecca J. Freeman, Victoria Chan, Megan C. Blair, George Q. Daley, Leonard I. Zon

Blood (2024) 144 (Supplement 1): 4043.

https://doi.org/10.1182/blood-2024-208498

Published: 2024

Journal Articles

Transcription Factor Programming of Human iPSC-Derived Sinusoidal Vascular Endothelial Cells Enhances Co-Cultured Hematopoietic Stem and Progenitor Cell Transplantation

Tianxiao Han, Rajesh D. Gunage, Ran Jing, Olivia Stockard, Alexandra F. Corbin, Luca Hensch, Yang Tang, Kenny Chen, Song Yang, Yi Zhou, George Q. Daley, Thorsten M. Schlaeger, Leonard I. Zon

Blood (2024) 144 (Supplement 1): 820.

https://doi.org/10.1182/blood-2024-208453

Published: 2024

Journal Articles

Generation of Functional iPSC-Derived CAR-T Cells for Cancer Immunotherapy Via G9a/GLP Inhibition

Ran Jing, Marcelo Falchetti, Tianxiao Han, Mohamad Najia, Luca Hensch, Eleanor Meader, Martin Kononov, Stephanie Wang, Caroline Kubaczka, Edroaldo Lummertz Da Rocha, Robert Grant Rowe, Thorsten M. Schlaeger, Marcela Maus, Trista E. North, Leonard I. Zon, George Q. Daley

Blood (2024) 144 (Supplement 1): 2043.

https://doi.org/10.1182/blood-2024-208634

Published: 2024

Journal Articles

Exposure of hiPSC-Derived Mature Megakaryocytes to Vincristine Boosts Platelet Biogenesis in Vitro

Yasuo Harada, Emiri Nakamura, Trevor Bingham, Leonard I. Zon, George Q. Daley, Andrew Frelinger, Koji Eto, Thorsten M. Schlaeger

Blood (2023) 142 (Supplement 1): 1292.

https://doi.org/10.1182/blood-2023-185254

Published: 2023

Journal Articles

In Vivo Reprogramming of Adult Liver Sinusoidal Vascular Endothelial Cells into a Hematopoietic Stem and Progenitor Cell Niche

Tianxiao Han, Rajesh D. Gunage, Ran Jing, Alexandra F. Corbin, Kenny Zhi Ming Chen, Yang Tang, Olivia Stockard, Song Yang, Yi Zhou, George Q. Daley, Thorsten M. Schlaeger, Leonard I. Zon

Blood (2023) 142 (Supplement 1): 4071.

https://doi.org/10.1182/blood-2023-180300

Published: 2023

Journal Articles

Blood Flow Directs Yap/Taz-Mediated Transcriptional Regulation of Self-Renewal Programs to Control Developmental HSPC Expansion By Mechanical Stimulation of Piezo1

Blood (2023) 142 (Supplement 1): 1309.

https://doi.org/10.1182/blood-2023-190416

Published: 2023

Journal Articles

Lin28b- Let-7 -PRC1 Axis Guides Developmental Maturation of the Hematopoietic System

Mayuri Tanaka-Yano, Dahai Wang, Eleanor Meader, Melissa A. Kinney, Vivian Morris, Edroaldo Lummertz da Rocha, Nan Liu, Stuart H. Orkin, Trista E. North, George Q. Daley, Robert Grant Rowe

Blood (2021) 138 (Supplement 1): 21.

https://doi.org/10.1182/blood-2021-146004

Published: 2021

Journal Articles

Single Cell Analysis Elucidates the Maturation of Human Stem and Progenitor Cell Function from Fetal through Adult Hematopoiesis

Hojun Li, Jideofor Ezike, Anton Afanassiev, Laura Greenstreet, Stephen Zhang, Jennifer S. Whangbo, Vincent Butty, Enrico Moiso, Guinevere Connelly, Vivian Morris, Dahai Wang, George Q. Daley, Salil Garg, Stella T. Chou, Aviv Regev, Edroaldo Lummertz da Rocha, Geoffrey Schiebinger, R. Grant Rowe

Blood (2021) 138 (Supplement 1): 1079.

https://doi.org/10.1182/blood-2021-151090

Published: 2021

Journal Articles

Single Cell Resolution Mapping of Hematopoietic Stem and Progenitor Cell States throughout Human Life

Hojun Li, MD PhD, Vincent Butty, Guinevere Connelly, Vivian Morris, George Q. Daley, MD PhD, Jennifer Whangbo, MD PhD, Edroaldo Lummertz da rocha, PhD, Robert Grant Rowe, MDPhD

Blood (2020) 136 (Supplement 1): 31.

https://doi.org/10.1182/blood-2020-136380

Published: 2020

Journal Articles

Mechanisms of Leukemia Stem Cell Plasticity Revealed By Single Cell Analysis

R. Grant Rowe, George Q. Daley, MD PhD, Trista E. North, PhD, William Marion, Yana Pikman, MD, Marian H. Harris, MD PhD, Vivian Morris, Edroaldo Lummertz da rocha, PhD, Alex K. Shalek, PhD, Travis Hughes, Prerana Sensharma, Dahai Wang, Patricia Sousa, Shannan Ho Sui, Sergey Naumenko, Renan Vinicius Da Silva

Blood (2020) 136 (Supplement 1): 32.

https://doi.org/10.1182/blood-2020-135998

Published: 2020

Journal Articles

An Essential Role for the RNA Editor-Exonuclease Axis in Terminal Erythroid Differentiation

Blood (2020) 136 (Supplement 1): 3.

https://doi.org/10.1182/blood-2020-142757

Published: 2020

Journal Articles

Ezh1 Inhibits Commitment to Hemogenic Fate and HSPC Formation during Vertebrate Development

Rebecca Soto, BS, Edroaldo Lummertz da rocha, PhD, Linda T Vo, PhD, Mariam Hachimi, PhD, Jenna M Frame, PhD, Paul J. Wrighton, PhD, Wolfram Goessling, MD PhD, George Q. Daley, MD PhD, Trista E North, PhD

Blood (2019) 134 (Supplement_1): 3710.

https://doi.org/10.1182/blood-2019-131464

Published: 2019

Journal Articles

Optimized Beta-Globin Expression and Enucleation from Induced Red Blood Cells for In Vitro Modeling of Sickle Cell Disease

Tolulope O Rosanwo, BA, Melissa Kinney, PhD, Martha A Clark, PhD, Linda T Vo, PhD, R. Grant Rowe, MD PhD, Natasha M. Archer, MD, Matthew M Heeney, MD, Thorsten Schlaeger, PhD, Daniel E. Bauer, MD PhD, Mark D. Fleming, MD DPhil, Manoj T Duraisingh, PhD, Stuart H. Orkin, MD, Carlo Brugnara, MD, Trista North, PhD, George Q. Daley, MD PhD

Blood (2018) 132 (Supplement 1): 2359.

https://doi.org/10.1182/blood-2018-99-114136

Published: 2018

Journal Articles

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Jenna M Frame, PhD, Timothy Long, Caroline Schuster-Kubaczka, PhD, Virginie Esain, PhD, Sung Eun Lim, PhD, George Q. Daley, MD PhD, Trista North, PhD

Blood (2018) 132 (Supplement 1): 330.

https://doi.org/10.1182/blood-2018-99-117076

Published: 2018

Journal Articles

Modeling Fanconi Anemia Using Human Induced Pluripotent Stem Cells By Reversible Complementation

R. Grant Rowe, MD PhD, William Marion, Sonya Ruiz-Torres, Edroaldo Lummertz da Rocha, Yosra Girvan, Thorsten Schlaeger, PhD, Trista E. North, PhD, Susanne Wells, George Q. Daley, MD PhD

Blood (2018) 132 (Supplement 1): 3856.

https://doi.org/10.1182/blood-2018-99-111701

Published: 2018

Journal Articles

Novel Epigenetic Vulnerabilities for Diffuse Large B-Cell Lymphoma

Deepak Jha, PhD, George Q. Daley, MD PhD, Benoit Laurent, PhD, Cheng Zhang, PhD, Caroline Kubaczka, PhD, Bjoern Chapuy, MD PhD, Patricia Sousa, Pavlos Missios, MD PhD, R. Grant Rowe, MD PhD, Yu-Chung Huang, MD, Yang Tan, Jessica Barragan, Trista North, PhD, Thorsten Schlaeger, PhD, Hu Li, PhD, Yang Shi, PhD, Margaret A. Shipp, MD

Blood (2018) 132 (Supplement 1): 2600.

https://doi.org/10.1182/blood-2018-99-115030

Published: 2018

Journal Articles

Piezo1-Sensitive Biomechanical Pulsation Stimulates Long-Term Hematopoietic Stem Cell Formation

Giorgia Scapin, PhD, Jennifer Cillis, B.S., Taylor Patch, Priyanka R Dharampuriya, M.S., Elliott J. Hagedorn, PhD, Vanessa Lundin, Owen J Tamplin, PhD, Heidi Andeson, Leonard I. Zon, MD, George Q. Daley, MD PhD, Dhvanit I Shah, PhD PharmD

Blood (2018) 132 (Supplement 1): 3826.

https://doi.org/10.1182/blood-2018-99-110265

Published: 2018

Journal Articles

Enucleation and Beta-Globin Expression in Induced Red Blood Cells: A Platform to Model Sickle Cell Anemia

Tolulope O Rosanwo, BA, Melissa Kinney, PhD, Linda T Vo, PhD, Vanessa Lundin, PhD, George Q. Daley, MD PhD

Blood (2017) 130 (Supplement 1): 538.

https://doi.org/10.1182/blood.V130.Suppl_1.538.538

Published: 2017

Journal Articles

The Age of the Hematopoietic Microenvironment Specifies Lineage Commitment in MLL-Rearranged Leukemia

Grant Rowe, MD PhD, Edroaldo Lummertz da Rocha, Patricia Sousa, Pavlos Missios, Michael Morse, Jessica Barragan, Ronald Mathieu, George Q Daley, MD PhD

Blood (2017) 130 (Supplement 1): 135.

https://doi.org/10.1182/blood.V130.Suppl_1.135.135

Published: 2017

Journal Articles

Engineering of Induced Pluripotent Stem Cell-Derived Hemogenic Endothelium

Jerry Lee, MPhil, MS, Ryohichi Sugimura, MD PhD, George Q Daley, MD PhD

Blood (2017) 130 (Supplement 1): 2424.

https://doi.org/10.1182/blood.V130.Suppl_1.2424.2424

Published: 2017

NARROW

Chemical Modulation of ELF1 Binding to RUNX1 Target Genes Leads to Increased Hematopoietic Stem Cell Self-Renewal

Transcription Factor Programming of Human iPSC-Derived Sinusoidal Vascular Endothelial Cells Enhances Co-Cultured Hematopoietic Stem and Progenitor Cell Transplantation

Generation of Functional iPSC-Derived CAR-T Cells for Cancer Immunotherapy Via G9a/GLP Inhibition

Exposure of hiPSC-Derived Mature Megakaryocytes to Vincristine Boosts Platelet Biogenesis in Vitro

In Vivo Reprogramming of Adult Liver Sinusoidal Vascular Endothelial Cells into a Hematopoietic Stem and Progenitor Cell Niche

Blood Flow Directs Yap/Taz-Mediated Transcriptional Regulation of Self-Renewal Programs to Control Developmental HSPC Expansion By Mechanical Stimulation of Piezo1

Lin28b- Let-7 -PRC1 Axis Guides Developmental Maturation of the Hematopoietic System

Single Cell Analysis Elucidates the Maturation of Human Stem and Progenitor Cell Function from Fetal through Adult Hematopoiesis

Single Cell Resolution Mapping of Hematopoietic Stem and Progenitor Cell States throughout Human Life

Mechanisms of Leukemia Stem Cell Plasticity Revealed By Single Cell Analysis

An Essential Role for the RNA Editor-Exonuclease Axis in Terminal Erythroid Differentiation

Ezh1 Inhibits Commitment to Hemogenic Fate and HSPC Formation during Vertebrate Development

Optimized Beta-Globin Expression and Enucleation from Induced Red Blood Cells for In Vitro Modeling of Sickle Cell Disease

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Modeling Fanconi Anemia Using Human Induced Pluripotent Stem Cells By Reversible Complementation

Novel Epigenetic Vulnerabilities for Diffuse Large B-Cell Lymphoma

Piezo1-Sensitive Biomechanical Pulsation Stimulates Long-Term Hematopoietic Stem Cell Formation

Enucleation and Beta-Globin Expression in Induced Red Blood Cells: A Platform to Model Sickle Cell Anemia

The Age of the Hematopoietic Microenvironment Specifies Lineage Commitment in MLL-Rearranged Leukemia

Engineering of Induced Pluripotent Stem Cell-Derived Hemogenic Endothelium

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American Society of Hematology

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American Society of Hematology

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