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Journal Articles

Transcription Factor Programming of Human iPSC-Derived Sinusoidal Vascular Endothelial Cells Enhances Co-Cultured Hematopoietic Stem and Progenitor Cell Transplantation

Tianxiao Han, Rajesh D. Gunage, Ran Jing, Olivia Stockard, Alexandra F. Corbin, Luca Hensch, Yang Tang, Kenny Chen, Song Yang, Yi Zhou, George Q. Daley, Thorsten M. Schlaeger, Leonard I. Zon

Blood (2024) 144 (Supplement 1): 820.

https://doi.org/10.1182/blood-2024-208453

Published: 2024

Journal Articles

Generation of Functional iPSC-Derived CAR-T Cells for Cancer Immunotherapy Via G9a/GLP Inhibition

Ran Jing, Marcelo Falchetti, Tianxiao Han, Mohamad Najia, Luca Hensch, Eleanor Meader, Martin Kononov, Stephanie Wang, Caroline Kubaczka, Edroaldo Lummertz Da Rocha, Robert Grant Rowe, Thorsten M. Schlaeger, Marcela Maus, Trista E. North, Leonard I. Zon, George Q. Daley

Blood (2024) 144 (Supplement 1): 2043.

https://doi.org/10.1182/blood-2024-208634

Published: 2024

Journal Articles

Blood Flow Directs Yap/Taz-Mediated Transcriptional Regulation of Self-Renewal Programs to Control Developmental HSPC Expansion By Mechanical Stimulation of Piezo1

Blood (2023) 142 (Supplement 1): 1309.

https://doi.org/10.1182/blood-2023-190416

Published: 2023

Journal Articles

Exposure of hiPSC-Derived Mature Megakaryocytes to Vincristine Boosts Platelet Biogenesis in Vitro

Yasuo Harada, Emiri Nakamura, Trevor Bingham, Leonard I. Zon, George Q. Daley, Andrew Frelinger, Koji Eto, Thorsten M. Schlaeger

Blood (2023) 142 (Supplement 1): 1292.

https://doi.org/10.1182/blood-2023-185254

Published: 2023

Journal Articles

In Vivo Reprogramming of Adult Liver Sinusoidal Vascular Endothelial Cells into a Hematopoietic Stem and Progenitor Cell Niche

Tianxiao Han, Rajesh D. Gunage, Ran Jing, Alexandra F. Corbin, Kenny Zhi Ming Chen, Yang Tang, Olivia Stockard, Song Yang, Yi Zhou, George Q. Daley, Thorsten M. Schlaeger, Leonard I. Zon

Blood (2023) 142 (Supplement 1): 4071.

https://doi.org/10.1182/blood-2023-180300

Published: 2023

Journal Articles

Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium

Il Ho Jang, Yi-Fen Lu, Long Zhao, Pamela L. Wenzel, Tsutomu Kume, Sumon M. Datta, Natasha Arora, Jordi Guiu, Mounia Lagha, Peter G. Kim, Eun Kyoung Do, Jae Ho Kim, Thorsten M. Schlaeger, Leonard I. Zon, Anna Bigas, Caroline E. Burns, George Q. Daley

Blood (2015) 125 (9): 1418–1426.

https://doi.org/10.1182/blood-2014-04-568170

Published: 2015

Includes: Supplemental data

Journal Articles

Modeling Diamond Blackfan Anemia in Vivo Using Human Induced Pluripotent Stem Cells

Sergei Doulatov, PhD, Linda T Vo, Elizabeth R Macari, PhD, Stephanie S Chou, Manav Gupta, Michelle Godfrey, Katherine McGrath, Thorsten M Schlaeger, PhD, Leonard I. Zon, MD, George Q. Daley, MD PhD

Blood (2014) 124 (21): 359.

https://doi.org/10.1182/blood.V124.21.359.359

Published: 2014

Journal Articles

Epoxyeicosatrienoic Acids Regulate Hematopoietic Stem/Progenitor Cell Fate Decision During Stress Response and Embryonic Hematopoiesis

Pulin Li, Emily K Pugach, Elizabeth B Riley, Dipak Panigrahy, M.D., Garrett C Heffner, PhD, Teresa V. Bowman, PhD, Owen J. Tamplin, PhD, Shannon McKinney-Freeman, PhD, Thorsten M Schlaeger, PhD, George Q. Daley, MD, PhD, Darryl C Zeldin, M.D., Leonard I. Zon, MD

Blood (2011) 118 (21): 860.

https://doi.org/10.1182/blood.V118.21.860.860

Published: 2011

Journal Articles

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

Asmin Tulpule, M. William Lensch, Justine D. Miller, Karyn Austin, Alan D'Andrea, Thorsten M. Schlaeger, Akiko Shimamura, George Q. Daley

Blood (2010) 115 (17): 3453–3462.

https://doi.org/10.1182/blood-2009-10-246694

Published: 2010

Includes: Supplemental data

Journal Articles

ABC-Me (ABCB10) Is Required for Erythroid Development in the Mouse Embryo and Is Protective against Mitochondrial Oxidative Stress

Brigham B Hyde, Alvaro A Elorza, PhD, Hanna K Mikkola, MD/PhD, Thorsten M Schlaeger, PhD, Orian S Shirihai, MD/PhD

Blood (2008) 112 (11): 529.

https://doi.org/10.1182/blood.V112.11.529.529

Published: 2008

Journal Articles

Targeted Disruption of the Mouse Mitoferrin (Slc25A37) Mitochondrial Solute Carrier Results in Defective Primitive and Definitive Erythropoiesis.

Barry H. Paw, MD, PhD, Babette Gwynn, M.S., Nathaniel B. Langer, B.A., George C. Shaw, B.A., Amy J. Lambert, B.S., Leah A. Boyer, B.A., Liangtao Li, M.D., Jens Stolte, Raymond F. Robledo, Ph.D., Kenneth E. Sahr, Ph.D., Thorsten M. Schlaeger, Ph.D., Matthias W. Hentze, M.D., Martina U. Muckenthaler, Ph.D., Jerry Kaplan, Ph.D., Luanne L. Peters, Ph.D.

Blood (2006) 108 (11): 265.

https://doi.org/10.1182/blood.V108.11.265.265

Published: 2006

Journal Articles

Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1) –dependent window during hematopoietic stem-cell development

Thorsten M. Schlaeger, Hanna K. A. Mikkola, Christos Gekas, Hildur B. Helgadottir, Stuart H. Orkin

Blood (2005) 105 (10): 3871–3874.

https://doi.org/10.1182/blood-2004-11-4467

Published: 2005

Journal Articles

Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo

Hanna K. A. Mikkola, Yuko Fujiwara, Thorsten M. Schlaeger, David Traver, Stuart H. Orkin

Blood (2003) 101 (2): 508–516.

https://doi.org/10.1182/blood-2002-06-1699

Published: 2003

Journal Articles

Role of SCL/Tal-1, GATA, and Ets transcription factor binding sites for the regulation of Flk-1 expression during murine vascular development

Andreas Kappel, Thorsten M. Schlaeger, Ingo Flamme, Stuart H. Orkin, Werner Risau, Georg Breier

Blood (2000) 96 (9): 3078–3085.

https://doi.org/10.1182/blood.V96.9.3078

Published: 2000

NARROW

Transcription Factor Programming of Human iPSC-Derived Sinusoidal Vascular Endothelial Cells Enhances Co-Cultured Hematopoietic Stem and Progenitor Cell Transplantation

Generation of Functional iPSC-Derived CAR-T Cells for Cancer Immunotherapy Via G9a/GLP Inhibition

Blood Flow Directs Yap/Taz-Mediated Transcriptional Regulation of Self-Renewal Programs to Control Developmental HSPC Expansion By Mechanical Stimulation of Piezo1

Exposure of hiPSC-Derived Mature Megakaryocytes to Vincristine Boosts Platelet Biogenesis in Vitro

In Vivo Reprogramming of Adult Liver Sinusoidal Vascular Endothelial Cells into a Hematopoietic Stem and Progenitor Cell Niche

Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium

Modeling Diamond Blackfan Anemia in Vivo Using Human Induced Pluripotent Stem Cells

Epoxyeicosatrienoic Acids Regulate Hematopoietic Stem/Progenitor Cell Fate Decision During Stress Response and Embryonic Hematopoiesis

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

ABC-Me (ABCB10) Is Required for Erythroid Development in the Mouse Embryo and Is Protective against Mitochondrial Oxidative Stress

Targeted Disruption of the Mouse Mitoferrin (Slc25A37) Mitochondrial Solute Carrier Results in Defective Primitive and Definitive Erythropoiesis.

Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1) –dependent window during hematopoietic stem-cell development

Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo

Role of SCL/Tal-1, GATA, and Ets transcription factor binding sites for the regulation of Flk-1 expression during murine vascular development

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American Society of Hematology

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ASH Publications

American Society of Hematology

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