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Vijay Bhoj
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Journal Articles

Precision targeting of autoantibody-producing IGHV1-69+ B cells in immune-mediated thrombotic thrombocytopenic purpura (iTTP) using chimeric antigen receptor T cells

Free
Ivan Cohen, Roman Khadka, Jean Lemoine, Audrey Bochi-Layec, Seul Jung, Ki Hyun Kim, Huiwu Zhao, Morgan Hresko, Don Siegel, Paolo Ghia, Kostas Stamatopoulos, Stephen Schuster, Vijay Bhoj, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 426.
https://doi.org/10.1182/blood-2025-426
Published: 2025
Journal Articles

Delayed neurotoxicity, enterocolitis, and BCMA-CART-associated immune-related adverse events (CirAE)  are caused by CD4+ CAR T-cells

Free
Julia Han Noll, Matthew Ho, Luca Paruzzo, Federico Stella, Pooja Devi, Sonia Ndeupen, Gregory Chen, Ivan Cohen, Angel Ramirez-Fernandez, Adam Waxman, Shivani Kapur, Fang Chen, Rong Xu, Andrew Huff, Danuta Jarocha, Vrutti Patel, Audrey Bochi-Layec, Ranjani Ramasubramanian, Shan Liu, Riemke Bouvier, Vitor Souza, Heta Patel, Ziyu Li, Alberto Carturan, Peter Michener, Caitlin Hopkins, Owen Koucky, Janna Minehart, Alex Dimitri, Neel Nabar, Zainul Hasanali, Bryan Ciccarelli, Erik Williams, Robert Bartoszek, Maya Lavorando, Suyash Mohan, Vanessa Gonzalez, Patrizia Porazzi, Vijay Bhoj, Sokratis Apostolidis, Dan Vogl, David Porter, John Scholler, Caroline Diorio, Aoife Doto, John Everett, Frederic Bushman, Katherine Nathanson, Edward Stadtmauer, Sandra Susanibar-Adaniya, Alfred Garfall, Marco Ruella, Adam Cohen, Joseph Fraietta
Journal: Blood
Blood (2025) 146 (Supplement 1): 804.
https://doi.org/10.1182/blood-2025-804
Published: 2025
Journal Articles

Chimeric antigen receptor T-cell therapy in patients with coexisting malignancy and autoimmune disease

Free
Luca Paruzzo, Riemke Bouvier, Bria Fulmer, Ivan Cohen, Elise Chong, Jakub Svoboda, Sunita Dwivedy Nasta, Daniel Landsburg, Vrutti Patel, Matthew Ho, Alberto Carturan, Federico Stella, Adam Waxman, Adam Cohen, Dan Vogl, Stefan Barta, Audrey Bochi-Layec, Patrizia Porazzi, Joseph Fraietta, Alfred Garfall, Vijay Bhoj, Edward Stadtmauer, David Porter, James Riley, Peter Merkel, Stephen Schuster, Jordan Carter, Sokratis Apostolidis, Sandra Susanibar-Adaniya, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 4543.
https://doi.org/10.1182/blood-2025-4543
Published: 2025
Journal Articles

Elimination of alloantibody responses using chimeric HLA-II antibody receptor T cells

Free
Georgia Papadaki, Huiwu Zhao, Yang Li, Dimitri Monos, Vijay Bhoj
Journal: Blood
Blood (2025) 146 (Supplement 1): 4128.
https://doi.org/10.1182/blood-2025-4128
Published: 2025
Journal Articles

Precision targeting of pathogenic B cells and autoantibodies in systemic lupus erythematosus using CAR T cells against the IGHV4-34 B cell receptor

Free
Audrey Bochi-Layec, Ivan Cohen, Jean Lemoine, Scott Jenks, Pedram Bayat, Ki Hyun Kim, Huiwu Zhao, Ositadimma Ugwuanyi, Federico Stella, Guido Ghilardi, Giulia Gabrielli, Sarah McCuaig, Anastasia Iatrou, Elisavet Vlachonikola, Maria Karypidou, Eleni Bouziani, Ranjani Ramasubramanian, Andreas Agathangelidis, Luca Paruzzo, Regina Bugrovsky, Puneeth Guruprasad, Li-Ping Wang, Jaryse Harris, Yunlin Zhang, Raymone Pajarillo, Portia Kreiger, Bria Fulmer, Marcos Cases, Patrizia Porazzi, E. John Wherry, Sokratis Apostolidis, Vijay Bhoj, Stephen J. Schuster, Paolo Ghia, Kostas Stamatopoulos, Edward Behrens, Ignacio Sanz, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 4120.
https://doi.org/10.1182/blood-2025-4120
Published: 2025
Journal Articles

Precision targeting of immune-mediated thrombotic thrombocytopenic purpura (iTTP) with chimeric auto-antigen receptor (CAAR) T cells

Free
Roman Khadka, Ivan Cohen, Kalpana Parvathaneni, Jean Lemoine, Seul Jung, Audrey Bochi-Layec, Huiwu Zhao, Morgan Hresko, Don Siegel, Marco Ruella, Vijay Bhoj
Journal: Blood
Blood (2025) 146 (Supplement 1): 2341.
https://doi.org/10.1182/blood-2025-2341
Published: 2025
Journal Articles

Efficacy and Safety of Anti-CD19 and Anti-BCMA Chimeric Antigen Receptor (CAR) T-Cell Therapies in Patients with Autoimmune Disease and Lymphoma or Myeloma

Free
Luca Paruzzo, Riemke Bouvier, Guido Ghilardi, Eugenio Fardella, Bria Fulmer, Ivan J Cohen, Elise A. Chong, Jakub Svoboda, Sunita D. Nasta, Daniel J. Landsburg, Vrutti Patel, Li Ziyu, Raymone Pajarillo, Adam Waxman, Adam D. Cohen, Dan T. Vogl, Stefan K. Barta, Patrizia Porazzi, Joseph A. Fraietta, Vijay Bhoj, Alfred L. Garfall, Edward A. Stadtmauer, Stephen J. Schuster, Jordan S. Carter, Sokratis A. Apostolidis, Sandra Susanibar-Adaniya, Marco Ruella
Journal: Blood
Blood (2024) 144 (Supplement 1): 7243.
https://doi.org/10.1182/blood-2024-206608
Published: 2024
Journal Articles

Targeted-Delivery Strategy of Engineered EV Functionalized By Anti-CD3/CD19 Bi-Specific T-Cell Engager in Treating B-Cell Malignancies

Free
Xiuiu Yang, Shanwei Ye, Qian Xu, Jue Wang, Caroline Markmann, Lingfeng Zhang, Shujia Zhang, Xinyue Deng, Jiali Cheng, Jia Wu, Vijay Bhoj, Zheng Zhang, Liang Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 89.
https://doi.org/10.1182/blood-2024-210125
Published: 2024
Journal Articles

Gut Microbiota Tuning Promotes Tumor-Associated Antigen Cross Presentation and Enhances CAR T Antitumor Effects

Free
Marco Ruella, Mireia Uribe-Herranz, Silvia Beghi, Kalpana Parvathaneni, Nektarios Kostopoulos, Guido Ghilardi, Kimberly Amelsberg, Yong Gu Gu Lee, Raymone Pajarillo, Noelle V Frey, Simon F Lacey, Khatuna Gabunia, John Scholler, Elise A Chong, Carl H June, David L. Porter, Stephen J. Schuster, Vijay Bhoj, Andrea Facciabene
Journal: Blood
Blood (2021) 138 (Supplement 1): 163.
https://doi.org/10.1182/blood-2021-151093
Published: 2021
Journal Articles

Ontogeny of the Alloimmune Anti-Canine Factor VIII Inhibitor Response in Severe Hemophilia Α Dogs

Free
Robert Chen, Bhavya S Doshi, Timothy C. Nichols, Michael C. Milone, Ben J. Samelson-Jones, Valder R Arruda, Vijay Bhoj, Don L. Siegel
Journal: Blood
Blood (2021) 138 (Supplement 1): 3173.
https://doi.org/10.1182/blood-2021-149215
Published: 2021
Journal Articles

Adoptive Immune Responses to Sars-Cov2 Vaccination in CART19 Treated Patients

Free
Kalpana Parvathaneni, Kyabeth Toress-Rodriguez, Wenzhao Meng, James Knox, Xiaoming Xu, Daniela Weiskopf, Noelle V Frey, Eline Luning-Prak, Alfred L Garfall, Michael Betts, Wei-Ting Hwang, David L Porter, Carl H June, Ali Naji, Vijay Bhoj
Journal: Blood
Blood (2021) 138 (Supplement 1): 1757.
https://doi.org/10.1182/blood-2021-153730
Published: 2021
Journal Articles

Optimized FVIII-Domain-Based Chimeric Antigen Receptors to Specifically Target FVIII Inhibitor-Producing B Cells in Hemophilia a

Free
Vijay Bhoj, MD PhD, Lucy Li, Benjamin J. Samelson-Jones, MD PhD, Bhavya S Doshi, MD, Christoph Ellebrecht, MD, Aimee Payne, MD PhD, Valder R Arruda, MD PhD, Michael C. Milone, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2196.
https://doi.org/10.1182/blood-2018-99-120031
Published: 2018
Journal Articles

The Thrombotic Microangiopathy Registry of North America

Free
Ara Metjian, MD, Yvette Tanhehco, MD, Huy Phu Pham, MD, M.P.H., Nicole A. Aqui, MD, Vijay Bhoj, MD PhD, Oluwatoyosi Onwuemene, MD, Marisa Marques, MD, Gowthami M Arepally, MD
Journal: Blood
Blood (2015) 126 (23): 5587.
https://doi.org/10.1182/blood.V126.23.5587.5587
Published: 2015
Journal Articles

Humoral Immunity and Plasma Cell Changes in Patients Responding to CD19-Specific Chimeric Antigen Receptor (CAR)-Modified T-Cell Adoptive Immunotherapy

Free
Vijay Bhoj, MD PhD, Michael C Milone, MD PhD, Carl H. June, MD, David Porter, MD, Stephan A. Grupp, MD PhD, Jan J Melenhorst, PhD, Simon F. Lacey, PhD BSc, Colleen Callahan, MSN, CRNP, James Capobianchi, Gerald Wertheim, MDPhD, Yolanda Mahnke, PhD
Journal: Blood
Blood (2014) 124 (21): 1110.
https://doi.org/10.1182/blood.V124.21.1110.1110
Published: 2014