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Journal Articles

Coagulation factor VIII: biological basis of emerging hemophilia A therapies

Benjamin J. Samelson-Jones, Bhavya S. Doshi, Lindsey A. George

Blood (2024) 144 (21): 2185–2197.

https://doi.org/10.1182/blood.2023023275

Published: 2024

Includes: Supplemental data

Journal Articles

Success of Immune Tolerance Induction after AAV Gene Therapy in High-Responding Inhibitor Hemophilia a Dogs May be F8 Genotype Dependent

Yani B Suber, Bhavya S Doshi, Robert A French, Elizabeth Merricks, Timothy Nichols, Ben Samelson-Jones

Blood (2024) 144 (Supplement 1): 3579.

https://doi.org/10.1182/blood-2024-199820

Published: 2024

Journal Articles

Enhanced procoagulant activity of select hemophilia B causing factor IX variants with emicizumab

Kyumin Lee, Julia Q. Chau, Yani B. Suber, Anna R. Sternberg, Allyson M. Pishko, Lindsey A. George, Vijay G. Bhoj, Bhavya S. Doshi, Benjamin J. Samelson-Jones

Blood (2024) 144 (11): 1230–1235.

https://doi.org/10.1182/blood.2023021944

Published: 2024

Includes: Supplemental data

Journal Articles

RNAing toward a new therapy for hemophilia

Bhavya S. Doshi, Robert F. Sidonio, Jr

Blood (2024) 143 (22): 2219–2221.

https://doi.org/10.1182/blood.2024024295

Published: 2024

Journal Articles

Hemophilia A Research Program (HARP): A Novel Study Design for a Multicenter and Decentralized Prospective Observational Longitudinal Cohort Study in Hemophilia A

Jill M Johnsen, Shannon L Meeks, Grier P Page, Bhavya S Doshi, Marian T Sullivan, Mary-Anne Ardini, Angela C Weyand, Lynn Malec

Blood (2023) 142 (Supplement 1): 5494.

https://doi.org/10.1182/blood-2023-191010

Published: 2023

Journal Articles

Platelet Electron Microscopy Does Not Correlate with Bleeding Scores in a Pediatric Population

Hilary Whitworth, Elizabeth Andrews, Eric Thompson, Leslie Raffini, Bhavya S Doshi, Michele P. Lambert

Blood (2023) 142 (Supplement 1): 1222.

https://doi.org/10.1182/blood-2023-181252

Published: 2023

Journal Articles

Long-Term Real-World Safety and Efficacy of Liver-Directed AAV Gene Therapy for Severe Hemophilia with and without Inbibitors in Privately Owned Dogs

Bhavya S Doshi, Ben J Samelson-Jones, Timothy C Nichols, Elizabeth P Merricks, Valder R Arruda, Mary Beth Callan

Blood (2022) 140 (Supplement 1): 7780–7781.

https://doi.org/10.1182/blood-2022-164470

Published: 2022

Journal Articles

Vector Analysis of Multicentric Lymphoma in a Severe Hemophilia Α Dog after AAV Gene Therapy

Lucas Van Gorder, Bhavya S. Doshi, Elinor Willis, Matthew Lanza, Valder R. Arruda, Mary Beth Callan, Ben J. Samelson-Jones

Blood (2022) 140 (Supplement 1): 4919–4920.

https://doi.org/10.1182/blood-2022-164440

Published: 2022

Journal Articles

Ontogeny of the Alloimmune Anti-Canine Factor VIII Inhibitor Response in Severe Hemophilia Α Dogs

Robert Chen, Bhavya S Doshi, Timothy C. Nichols, Michael C. Milone, Ben J. Samelson-Jones, Valder R Arruda, Vijay Bhoj, Don L. Siegel

Blood (2021) 138 (Supplement 1): 3173.

https://doi.org/10.1182/blood-2021-149215

Published: 2021

Journal Articles

Extra-Splenic Role of B Cell Activating Factor Blockade in Prevention of Factor VIII Inhibitors

Bhavya S Doshi, Mostafa A Shaheen, Juliana C Small, Paris Margaritis, Valder R Arruda

Blood (2021) 138 (Supplement 1): 1025.

https://doi.org/10.1182/blood-2021-149259

Published: 2021

Journal Articles

Clingen Coagulation Factor Deficiency Variant Curation Expert Panel: Meeting the Need for Recommendations to Curate Variants in the Coagulation Factor Genes

Shruthi Mohan, PhD, Kristy Lee, MS, CGC, Manuel Carcao, Bhavya S Doshi, MD, Kate Downes, PhD, Geoff Kemball-Cook, PhD, Frank Leebeek, MD PhD, Jamie McCreery, MS, CGC, Connie H. Miller, PhD, Amanda B Payne, MPH,PhD, Valerie Trapp-Stamborski, PhD, Barbara A. Konkle, MD, Keith Gomez, MBBS, PhD MRCP, FRCPath

Blood (2019) 134 (Supplement_1): 5794.

https://doi.org/10.1182/blood-2019-124842

Published: 2019

Journal Articles

Utility of Repeat Testing in the Evaluation for Von Willebrand Disease in Pediatric Patients

Bhavya S Doshi, MD, Rachel S Rogers, MS, Hilary B Whitworth, MD, Emily Stabnick, BA, Jessica Britton, BA, Regina Butler, RN-BC, Char M Witmer, MDMSCE

Blood (2018) 132 (Supplement 1): 981.

https://doi.org/10.1182/blood-2018-99-115607

Published: 2018

Journal Articles

Optimized FVIII-Domain-Based Chimeric Antigen Receptors to Specifically Target FVIII Inhibitor-Producing B Cells in Hemophilia a

Vijay Bhoj, MD PhD, Lucy Li, Benjamin J. Samelson-Jones, MD PhD, Bhavya S Doshi, MD, Christoph Ellebrecht, MD, Aimee Payne, MD PhD, Valder R Arruda, MD PhD, Michael C. Milone, MD PhD

Blood (2018) 132 (Supplement 1): 2196.

https://doi.org/10.1182/blood-2018-99-120031

Published: 2018

Journal Articles

The Un-BLyS-Ful State: Blocking Factor VIII Inhibitor Development with BLyS Depletion

Bhavya S Doshi, MD, Robert J. Davidson, BS, Valder R Arruda, MD PhD

Blood (2018) 132 (Supplement 1): 138.

https://doi.org/10.1182/blood-2018-99-114795

Published: 2018

Journal Articles

Novel Correlation between B Cell Survival Cytokines and Inhibitors in Hemophilia A

Bhavya S Doshi, MD, Simon F Lacey, PhD BS, Fang Chen, PhD, Leslie J Raffini, MD MSCE, Valder R Arruda, MD PhD

Blood (2017) 130 (Supplement 1): 3677.

https://doi.org/10.1182/blood.V130.Suppl_1.3677.3677

Published: 2017

Journal Articles

Novel approaches to hemophilia therapy: successes and challenges

Valder R. Arruda, Bhavya S. Doshi, Benjamin J. Samelson-Jones

Blood (2017) 130 (21): 2251–2256.

https://doi.org/10.1182/blood-2017-08-742312

Published: 2017

Journal Articles

Coagulopathy Predicts Mortality in Pediatric Patients with Traumatic Brain Injury

Bhavya S. Doshi, MD, Shannon L. Meeks, MD, Jeanne E Hendrickson, MD, Andrew Reisner, MD, Traci Leong, PhD, Anne M. Winkler, MD MSc, Erin Meyer, DO, MPH

Blood (2014) 124 (21): 2891.

https://doi.org/10.1182/blood.V124.21.2891.2891

Published: 2014

Journal Articles

A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function

Shannon L. Meeks, Courtney L. Cox, John F. Healey, Ernest T. Parker, Bhavya S. Doshi, Bagirath Gangadharan, Rachel T. Barrow, Pete Lollar

Blood (2012) 120 (12): 2512–2520.

https://doi.org/10.1182/blood-2012-02-412361

Published: 2012

Includes: Supplemental data

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Coagulation factor VIII: biological basis of emerging hemophilia A therapies

Success of Immune Tolerance Induction after AAV Gene Therapy in High-Responding Inhibitor Hemophilia a Dogs May be F8 Genotype Dependent

Enhanced procoagulant activity of select hemophilia B causing factor IX variants with emicizumab

RNAing toward a new therapy for hemophilia

Hemophilia A Research Program (HARP): A Novel Study Design for a Multicenter and Decentralized Prospective Observational Longitudinal Cohort Study in Hemophilia A

Platelet Electron Microscopy Does Not Correlate with Bleeding Scores in a Pediatric Population

Long-Term Real-World Safety and Efficacy of Liver-Directed AAV Gene Therapy for Severe Hemophilia with and without Inbibitors in Privately Owned Dogs

Vector Analysis of Multicentric Lymphoma in a Severe Hemophilia Α Dog after AAV Gene Therapy

Ontogeny of the Alloimmune Anti-Canine Factor VIII Inhibitor Response in Severe Hemophilia Α Dogs

Extra-Splenic Role of B Cell Activating Factor Blockade in Prevention of Factor VIII Inhibitors

Clingen Coagulation Factor Deficiency Variant Curation Expert Panel: Meeting the Need for Recommendations to Curate Variants in the Coagulation Factor Genes

Utility of Repeat Testing in the Evaluation for Von Willebrand Disease in Pediatric Patients

Optimized FVIII-Domain-Based Chimeric Antigen Receptors to Specifically Target FVIII Inhibitor-Producing B Cells in Hemophilia a

The Un-BLyS-Ful State: Blocking Factor VIII Inhibitor Development with BLyS Depletion

Novel Correlation between B Cell Survival Cytokines and Inhibitors in Hemophilia A

Novel approaches to hemophilia therapy: successes and challenges

Coagulopathy Predicts Mortality in Pediatric Patients with Traumatic Brain Injury

A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function

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