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Journal Articles

B Cell Receptor Inactivation Boosts NK Cell Killing of MYC-Driven Lymphomas

Gabriele Varano, Hiroshi Arima, Nicara C Parr, Eleonora Sala, Marta Mangione, Karlo Mladenic, Gaia Morello, Federica Mainoldi, Silvia Brambillasca, Adrian Andronache, Vanna Imsirovic, Ciro Mercurio, Felix Wensveen, Bojan Polic, Mirela Kuka, Claudio Tripodo, Stefano Casola
Journal: Blood
Blood (2024) 144 (Supplement 1): 334.
https://doi.org/10.1182/blood-2024-200555
Published: 2024
Journal Articles

B Cell Receptor Silencing Reveals Origin and Impacts Treatment of High-Grade B Cell Lymphomas with MYC and BCL2 Rearrangements

Stefano Casola, Paola Sindaco, Silvia Lonardi, Gabriele Varano, Ilaria Pietrini, Gaia Morello, Piera Balzarini, Hadas Neuman, Filippo Vit, Giorgio Bertolazzi, Hiroshi Arima, Marco Chiarini, Luisa Lorenzi, Vilma Pellegrini, Sabrina Giampaolo, Daniel Garzon, Cecilia Ranise, Mattia Bugatti, Chiara Pagani, Rosa Daffini, Federica Mainoldi, Viveka Selvarasa, Anojan Sivacegaram, Henry Yang, Li Ying, Valeria Cancila, Raoul Bonnal, Euplio Visco, Cristina Lopez Gonzalez, Pasquale Capaccio, Andrés José María Ferreri, Alessandra Tucci, Antonello Cabras, Giancarlo Pruneri, Arianna Di Napoli, Reiner Siebert, Riccardo Bomben, Brunangelo Falini, Marco Pizzi, Joo Y. Song, Wing Chung Chan, Maurilio Ponzoni, Ramit Mehr, Claudio Tripodo, Fabio Facchetti
Journal: Blood
Blood (2024) 144 (Supplement 1): 453.
https://doi.org/10.1182/blood-2024-203258
Published: 2024
Journal Articles

Inhibition of Fibroblast Growth Factor-23 (FGF-23) Rescues Bone and Hematopoietic Stem Cell Niche Defects in Beta-Thalassemia, Uncovering the Missing Link between Hematopoiesis and Bone

Annamaria Aprile, Laura Raggi, Simona Bolamperti, Mariangela Storto, Isabella Villa, Gaia Morello, Sarah Marktel, Claudio Tripodo, Irene Motta, Maria Domenica Cappellini, Alessandro Rubinacci, Giuliana Ferrari
Journal: Blood
Blood (2021) 138 (Supplement 1): 572.
https://doi.org/10.1182/blood-2021-148366
Published: 2021
Journal Articles

Hematopoietic stem cell function in β-thalassemia is impaired and is rescued by targeting the bone marrow niche

Annamaria Aprile, Alessandro Gulino, Mariangela Storto, Isabella Villa, Stefano Beretta, Ivan Merelli, Alessandro Rubinacci, Maurilio Ponzoni, Sarah Marktel, Claudio Tripodo, Maria Rosa Lidonnici, Giuliana Ferrari
Journal: Blood
Blood (2020) 136 (5): 610–622.
https://doi.org/10.1182/blood.2019002721
Published: 2020
Includes: Supplemental data
Journal Articles

Hematopoietic Stem Cell Function in β-Thalassemia Is Impaired and Is Rescued By Targeting the Bone Marrow Niche

Annamaria Aprile, PhD, Alessandro Gulino, PhD, Isabella Villa, PhD, Stefano Beretta, PhD, Ivan Merelli, PhD, Alessandro Rubinacci, MD, Maurilio Ponzoni, MD, Sarah Marktel, MD, Claudio Tripodo, MD, Maria Rosa Lidonnici, PhD, Giuliana Ferrari, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 967.
https://doi.org/10.1182/blood-2019-126829
Published: 2019
Journal Articles

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Cirino Botta, MD, Giuseppe Gaipa, PhD, Maria Eugenia Gallo Cantafio, PhD, Chiara Buracchi, PhD, Maria Anna Siciliano, MD, Caterina Riillo, MD, Katia Grillone, PhD, Alessandro Gulino, Maria Cucè, Nicoletta Staropoli, Andrea Ghelli Luserna Di Rora, Franca Maria Tuccillo, Maria Teresa Di Martino, Claudio Tripodo, MD, Marco Rossi, MD, Giovanni Martinelli, Andrea Biondi, MD, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1418.
https://doi.org/10.1182/blood-2018-99-118572
Published: 2018
Journal Articles

Bendamustine in Combination with Rituximab As First-Line Treatment of Splenic Marginal Zone Lymphoma (BRISMA). Results of the IELSG-36 Phase II Study

Emilio Iannitto, MD, Monica Bellei, MSc, PhD, Andrés J M Ferreri, MD, Luigi Marcheselli, MS, Marina Cesaretti, MD, Corinne Haioun, Salvatrice Mancuso, Krimo Bouabdallah, MD, Remy Gressin, MD, Claudio Tripodo, MD, Alexandra traverse-Glehen, MD PhD, Lucile Baseggio, MD, Simonetta Zupo, Caterina Stelitano, Barbara Castagnari, MD, Caterina Patti, MD, Francesco Merli, Anna Marina Liberati, MD, Michele Merli, Guido Gini, Maria Giuseppina Cabras, Jehan Dupuis, MD, Francesca Re, Emanuele Zucca, MD, Massimo Federico, MD, Catherine Thieblemont, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4062.
https://doi.org/10.1182/blood.V130.Suppl_1.4062.4062
Published: 2017
Journal Articles

Tumor Microenvironment (TME) Regulation of Programmed Death-1 (PD1) Receptor and Its Ligands PDL1 and PDL2 in Chronic Lymphocytic Leukemia (CLL)

Fortunato Morabito, MD, Sabrina Bossio, Claudio Tripodo, MD, Anna Recchia, PhD BS, PharmD, Laura De Stefano, Nadia Caruso, Angela Palummo, Francesca Storino, Massimo Gentile, MD, Ernesto Vigna, MD, Anna Maria Petrungaro, MD, Iolanda Donatella Vincelli, MD, Daniela Fenoglio, Gilberto Filaci, Franco Fais, Giuseppina Uccello, MD, Alessandro Gulino, Roberto Vallone, MD, Martina Manzoni, Antonino Neri, MD, Giovanna Cutrona, PhD, Pierfrancesco Tassone, MD, Manlio Ferrarini, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4291.
https://doi.org/10.1182/blood.V130.Suppl_1.4291.4291
Published: 2017
Journal Articles

Arginase 1 Is a Marker of Myeloid-Mediated Immunosuppression with Prognostic Meaning in Classic Hodgkin Lymphoma

Alessandra Romano, MD PhD, Nunziatina L Parrinello, Daniele Tibullo, PhD, Calogero Vetro, MD, Cesarina Giallongo, Piera La Cava, Annalisa Chiarenza, Loredana Villari, Claudio Tripodo, MD, Giovanna Motta, Laura Caruso, Andrea Gallamini, MD, Stefano A Pileri, Francesco Di Raimondo, MD
Journal: Blood
Blood (2016) 128 (22): 1770.
https://doi.org/10.1182/blood.V128.22.1770.1770
Published: 2016
Journal Articles

Microenvironment Regulation of IL23R/IL-23 Axis Drives Chronic Lymphocytic Leukemia (CLL) Progression

Fortunato Morabito, MD, Giovanna Cutrona, PhD, Anna Grazia Recchia, PhD, Marina Fabbi, Silvano Ferrini, Massimo Gentile, MD, Ernesto Vigna, Monica Colombo, Carlotta Massucco, MS, Sabrina Bossio, Laura De Stefano, Ugo Consoli, MD, Iolanda D. Vincelli, Caterina Musolino, Stefano Molica, MD, Antonino Neri, MD, Claudio Tripodo, MD, Manlio Ferrarini, MD
Journal: Blood
Blood (2015) 126 (23): 616.
https://doi.org/10.1182/blood.V126.23.616.616
Published: 2015
Journal Articles

Alteration of HSC Functions in Thalassemia

Annamaria Aprile, Maria Rosa Lidonnici, PhD, Alessandro Gulino, Claudio Tripodo, MD, Giacomo Mandelli, PhD, Giuliana Ferrari, PhD
Journal: Blood
Blood (2015) 126 (23): 4752.
https://doi.org/10.1182/blood.V126.23.4752.4752
Published: 2015
Journal Articles

HSPH1 inhibition downregulates Bcl-6 and c-Myc and hampers the growth of human aggressive B-cell non-Hodgkin lymphoma

Brief Report
Roberta Zappasodi, Giusi Ruggiero, Carla Guarnotta, Monica Tortoreto, Cristina Tringali, Alessandra Cavanè, Antonello D. Cabras, Lorenzo Castagnoli, Bruno Venerando, Nadia Zaffaroni, Alessandro M. Gianni, Filippo De Braud, Claudio Tripodo, Serenella M. Pupa, Massimo Di Nicola
Journal: Blood
Blood (2015) 125 (11): 1768–1771.
https://doi.org/10.1182/blood-2014-07-590034
Published: 2015
Includes: Supplemental data
Journal Articles

Dynamics of complement activation in aHUS and how to monitor eculizumab therapy

Clinical Trials & Observations
Marina Noris, Miriam Galbusera, Sara Gastoldi, Paolo Macor, Federica Banterla, Elena Bresin, Claudio Tripodo, Serena Bettoni, Roberta Donadelli, Elisabetta Valoti, Francesco Tedesco, Alessandro Amore, Rosanna Coppo, Piero Ruggenenti, Eliana Gotti, Giuseppe Remuzzi
Journal: Blood
Blood (2014) 124 (11): 1715–1726.
https://doi.org/10.1182/blood-2014-02-558296
Published: 2014
Includes: Supplemental data
Journal Articles

Bone marrow stroma CD40 expression correlates with inflammatory mast cell infiltration and disease progression in splenic marginal zone lymphoma

Giovanni Franco, Carla Guarnotta, Barbara Frossi, Pier Paolo Piccaluga, Emanuela Boveri, Alessandro Gulino, Fabio Fuligni, Alice Rigoni, Rossana Porcasi, Salvatore Buffa, Elena Betto, Ada Maria Florena, Vito Franco, Emilio Iannitto, Luca Arcaini, Stefano Aldo Pileri, Carlo Pucillo, Mario Paolo Colombo, Sabina Sangaletti, Claudio Tripodo
Journal: Blood
Blood (2014) 123 (12): 1836–1849.
https://doi.org/10.1182/blood-2013-04-497271
Published: 2014
Includes: Supplemental data
Journal Articles

New Therapeutic Approach for the Treatment of B-Cell Disorders Using Chlorambucil/Hydroxychloroquine-Loaded AntiCD20 Nanoparticles

Gabriele Pozzato, MD, Nelly Mezzaroba, PhD, Sonia Zorzet, PhD, Erika Secco, PhD, Stefania Biffi, PhD, Claudio Tripodo, MD, Marco Calvaruso, MD, Luis Nuñez, PhD, Rubens Spretz, PhD, Gustavo Larsen, PhD, Sandra Noriega, PhD, Chiara Garrovo, PhD, Gustavo Marin, MD, PhD, Edoardo Mansilla, MD, Paolo Macor, PhD
Journal: Blood
Blood (2012) 120 (21): 158.
https://doi.org/10.1182/blood.V120.21.158.158
Published: 2012
Journal Articles

The Pro-Inflammatory IL23/IL23R/IL17 Axis Is Active in IL23R-Expressing Circulating CLL Cells in Patients with Poor Prognosis

Fortunato Morabito, MD, Giovanna Cutrona, PhD, Anna Grazia Recchia, PhD, Sonia Fabris, PhD, Serena Matis, PhD, Monica Colombo, PhD, Sabrina Bossio, Massimo Gentile, MD, Carlotta Massucco, PhD, Laura De Stefano, Stefano Molica, MD, Caterina Musolino, MD, Fiorella Ilariucci, Gianluca Festini, MD, Francesco Di Raimondo, MD, Pierfrancesco Tassone, MD, Antonino Neri, Claudio Tripodo, MD, Manlio Ferrarini, MD
Journal: Blood
Blood (2012) 120 (21): 3889.
https://doi.org/10.1182/blood.V120.21.3889.3889
Published: 2012
Journal Articles

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion

Claudio Tripodo, Sabina Sangaletti, Carla Guarnotta, Pier P. Piccaluga, Matilde Cacciatore, Michela Giuliano, Giovanni Franco, Claudia Chiodoni, Marika Sciandra, Silvia Miotti, Giuseppe Calvaruso, Alessandra Carè, Ada M. Florena, Katia Scotlandi, Attilio Orazi, Stefano A. Pileri, Mario P. Colombo
Journal: Blood
Blood (2012) 120 (17): 3541–3554.
https://doi.org/10.1182/blood-2011-12-398537
Published: 2012
Includes: Supplemental data
Journal Articles

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

Sabina Sangaletti, Claudio Tripodo, Claudia Chiodoni, Carla Guarnotta, Barbara Cappetti, Patrizia Casalini, Silvia Piconese, Mariella Parenza, Cristiana Guiducci, Caterina Vitali, Mario P. Colombo
Journal: Blood
Blood (2012) 120 (15): 3007–3018.
https://doi.org/10.1182/blood-2012-03-416156
Published: 2012
Includes: Multimedia, Supplemental data
Journal Articles

The cumulative amount of serum-free light chain is a strong prognosticator in chronic lymphocytic leukemia

Clinical Trials & Observations
Fortunato Morabito, Rosaria De Filippi, Luca Laurenti, Katja Zirlik, Anna Grazia Recchia, Massimo Gentile, Emanuela Morelli, Ernesto Vigna, Vincenzo Gigliotti, Rosa Calemma, Barbara Amoroso, Antonino Neri, Giovanna Cutrona, Manlio Ferrarini, Stefano Molica, Giovanni Del Poeta, Claudio Tripodo, Antonio Pinto
Journal: Blood
Blood (2011) 118 (24): 6353–6361.
https://doi.org/10.1182/blood-2011-04-345587
Published: 2011
Includes: Supplemental data
Journal Articles

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

Sara Serra, Alberto L. Horenstein, Tiziana Vaisitti, Davide Brusa, Davide Rossi, Luca Laurenti, Giovanni D'Arena, Marta Coscia, Claudio Tripodo, Giorgio Inghirami, Simon C. Robson, Gianluca Gaidano, Fabio Malavasi, Silvia Deaglio
Journal: Blood
Blood (2011) 118 (23): 6141–6152.
https://doi.org/10.1182/blood-2011-08-374728
Published: 2011
Includes: Supplemental data