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Journal Articles

A Novel Bispecific T Cell Engager (UMG2-BTCE) Targeting CD1a-CD3ε Is Effective Against Cortical-Derived Acute Lymphoblastic Leukemia

Caterina Riillo, Daniele Caracciolo, Katia Grillone, Nicoletta Polerà, Giada Juli, Francesca Scionti, Serena Ascrizzi, Franca Maria Tuccillo, Patrizia Bonelli, Mariamena Arbitrio, Maria Teresa Di Martino, Pierosandro Tagliaferri, Pierfrancesco Tassone

Blood (2021) 138 (Supplement 1): 2259.

https://doi.org/10.1182/blood-2021-153043

Published: 2021

Journal Articles

Global Rnaseq/Proteomic-Phoshoproteomic Analysis Unveil Mir-21 As a Central Player in Driving Th17 Mediated Bone Disease in MM

Marco Rossi, MD, Emanuela Altomare, PhD, Cirino Botta, MD, Maria Eugenia Gallo Cantafio, Marco Gaspari, Domenico Taverna, Sarvide Sarai, Daniele Caracciolo, MD, Paola Critelli, MD, Francesco Conforti, Maria Teresa Di Martino, PhD, Bruno Paiva, PhD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2019) 134 (Supplement_1): 505.

https://doi.org/10.1182/blood-2019-122429

Published: 2019

Journal Articles

PARP1-Mediated Alt-NHEJ Repair Is a Therapeutic Target in Multiple Myeloma

Daniele Caracciolo, MD, Giada Juli, PhD, Francesca Scionti, PhD, Gaetanina Golino, PhD, Mariamena Arbitrio, MD, Emanuela Altomare, PhD, Katia Todoerti, PhD, Katia Grillone, PhD, Maria Teresa Di Martino, PhD, Marco Rossi, MD, Antonino Neri, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2019) 134 (Supplement_1): 3107.

https://doi.org/10.1182/blood-2019-128245

Published: 2019

Journal Articles

Functional Role of Linc-RNAs in Multiple Myeloma: Linc-MIR17HG Affects Fatty Acid Biosynthesis Via transcriptional Regulation of ACC1 with Potential Therapeutic Implications

Eugenio Morelli, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Francesca Scionti, Annamaria Gulla, MD, Nicola Amodio, PhD, Giada Bianchi, MD, Tommaso Perini, MD, Cinzia Federico, PhD, Michael A Lopez, Maria Teresa Di Martino, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD, Kenneth Anderson, MD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 1925.

https://doi.org/10.1182/blood-2018-99-119572

Published: 2018

Journal Articles

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Cirino Botta, MD, Giuseppe Gaipa, PhD, Maria Eugenia Gallo Cantafio, PhD, Chiara Buracchi, PhD, Maria Anna Siciliano, MD, Caterina Riillo, MD, Katia Grillone, PhD, Alessandro Gulino, Maria Cucè, Nicoletta Staropoli, Andrea Ghelli Luserna Di Rora, Franca Maria Tuccillo, Maria Teresa Di Martino, Claudio Tripodo, MD, Marco Rossi, MD, Giovanni Martinelli, Andrea Biondi, MD, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD

Blood (2018) 132 (Supplement 1): 1418.

https://doi.org/10.1182/blood-2018-99-118572

Published: 2018

Journal Articles

Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92

Blood (2018) 132 (10): 1050–1063.

https://doi.org/10.1182/blood-2018-03-836601

Published: 2018

Includes: Supplemental data

Journal Articles

Th17 Cells Targeting By MiR-21 Inhibitor Impairs Multiple Myeloma Related Bone Disease

Marco Rossi, Emanuela Altomare, Nicola Amodio, PhD, Maria Teresa Di Martino, Marco Gaspari, Domenico Taverna, Domenica Scumaci, Francesco Conforti, Daniele Caracciolo, Cirino Botta, Cinzia Federico, Annamaria Gullà, Eugenio Morelli, Francesca Scionti, Mariamena Arbitrio, MD, Paola Critelli, Antonino Neri, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD

Blood (2017) 130 (Supplement 1): 4380.

https://doi.org/10.1182/blood.V130.Suppl_1.4380.4380

Published: 2017

Journal Articles

Growth Inhibition and Synergistic Induction of Apoptosis By Synthetic Mir-125b-5p Mimics and Myc-Targeting Agents in Human Myeloma Cell Lines

Lavinia Biamonte, PhD, Cinzia Federico, PhD, Eugenio Morelli, MD, Emanuela Leone, PhD, Maria Eugenia Gallo Cantafio, PhD, Maria Teresa Di Martino, Nicola Amodio, PhD, Marco Rossi, MD, Antonino Neri, Pr, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2015) 126 (23): 3019.

https://doi.org/10.1182/blood.V126.23.3019.3019

Published: 2015

Journal Articles

Pharmacokinetics and Biodistribution of Locked Nucleic Acid (LNA)-Mir-221 Inhibitor: A New Promising Anti-Myeloma Agent

Maria Eugenia Gallo Cantafio, PhD, Annamaria Gulla, MD, Nicola Amodio, PhD, Emanuela Leone, PhD, Eugenio Morelli, MD, Lavinia Biamonte, PhD, Antonino Neri, Pr, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD, Maria Teresa Di Martino

Blood (2015) 126 (23): 3025.

https://doi.org/10.1182/blood.V126.23.3025.3025

Published: 2015

Journal Articles

Selective Activation of the Non-Classical Estrogen Receptor Gper Elicits Potent Anti-Tumor Activity in Multiple Myeloma

Nicola Amodio, PhD, Enrica Romeo, Maria Angelica Stamato, Eugenio Morelli, MD, Mariateresa Fulciniti, PhD, Lavinia Raimondi, Marzia Leotta, Maria Teresa Di Martino, Pierosandro Tagliaferri, MD, Nikhil C. Munshi, MD, Pierfrancesco Tassone, MD

Blood (2015) 126 (23): 916.

https://doi.org/10.1182/blood.V126.23.916.916

Published: 2015

Journal Articles

MiR-29b Counteracts Aberrant HDAC4 Expression and Enhances Vorinostat Activity in Multiple Myeloma

Nicola Amodio, PhD, Marzia Leotta, MD, Anna Maria Gullà, MD, Lavinia Raimondi, PhD, Eugenio Morelli, MD, Maria Angelica Stamato, Teresa Calimeri, MD PhD, Maria Teresa Di Martino, PhD, Marco Rossi, MD, Emanuela Leone, PhD, Antonino Neri, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2014) 124 (21): 2060.

https://doi.org/10.1182/blood.V124.21.2060.2060

Published: 2014

Journal Articles

Selective G-Protein Estrogen Receptor (GPER) Activation Triggers Anti-Multiple Myeloma Activity and Synergizes with MiR-29b-Inducing Drugs

Nicola Amodio, PhD, Marzia Leotta, MD, Eugenio Morelli, MD, Teresa Calimeri, MD PhD, Anna Maria Gullà, MD, Maria Angelica Stamato, Enrica Romeo, Umberto Foresta, PhDstudent, Antonino Neri, Maria Teresa Di Martino, PhD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2014) 124 (21): 4725.

https://doi.org/10.1182/blood.V124.21.4725.4725

Published: 2014

Journal Articles

Synthetic MiR-29b Mimics Potentiate Dendritic-Cell Based Immunotherapy Against Multiple Myeloma In Vitro and In Vivo

Cirino Botta, MD, Marco Rossi, MD, Maria Rita Pitari, PhD, Annamaria Gullà, MD, Teresa Del Giudice, MD, Eugenio Morelli, MD, Eleonora Iuliano, MD, Emanuela Altomare, PhD, Nicola Amodio, PhD, Maria Teresa Di Martino, PhD, Pierpaolo Correale, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2013) 122 (21): 4489.

https://doi.org/10.1182/blood.V122.21.4489.4489

Published: 2013

Journal Articles

Tumor Suppressor MiR-29b Targets HDAC4 and Modulates Vorinostat Activity In Multiple Myeloma Cells

Nicola Amodio, PhD, Marzia Leotta, MD, Lavinia Biamonte, PhD, Teresa Calimeri, MD, Eugenio Morelli, MD, Umberto Foresta, PhD, Maria Teresa Di Martino, PhD, Marco Rossi, MD, Emanuela Leone, PhD, Antonino Neri, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2013) 122 (21): 4451.

https://doi.org/10.1182/blood.V122.21.4451.4451

Published: 2013

Journal Articles

In Vitro and Vivo Activity Against Multiple Myeloma Cells Of a Novel Locked Nucleic Acid (LNA)-Mir-221 Inhibitor

Maria Teresa Di Martino, PhD, Annamaria Gullà, MD, Maria Eugenia Gallo Cantafio, Emanuela Altomare, PhD, Nicola Amodio, PhD, Emanuela Leone, PhD, Santo Giovanni Lio, Eugenio Morelli, MD, Daniele Caracciolo, MD, Cirino Botta, MD, Antonino Neri, MD, Niels M Frandsen, PhD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2013) 122 (21): 3166.

https://doi.org/10.1182/blood.V122.21.3166.3166

Published: 2013

Journal Articles

Inhibition Of Mir-21 In HS-5 Bone Marrow Stromal Cells In The Presence Of Multiple Myeloma cells Restores RANKL/OPG Ratio: A Potential Therapeutic Approach For Myeloma-Related Bone Disease

Maria Rita Pitari, PhD, Marco Rossi, MD, Cirino Botta, MD, Eugenio Morelli, MD, Annamaria Gullà, MD, Eleonora Iuliano, MD, Teresa Del Giudice, MD, Nicola Amodio, PhD, Maria Teresa Di Martino, PhD, Fortunato Morabito, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2013) 122 (21): 683.

https://doi.org/10.1182/blood.V122.21.683.683

Published: 2013

Journal Articles

MiR-29b Exerts Anti-Multiple Myeloma Activity by Targeting Key Oncogenic Pathways and Modulating DNA Methylation Profile.

Blood (2012) 120 (21): 2941.

https://doi.org/10.1182/blood.V120.21.2941.2941

Published: 2012

Journal Articles

Mir-29b Negatively Regulates Osteoclastic Cell Differentiation and Function: Implications for the Treatment of Multiple Myeloma-Related Bone Disease

Marco Rossi, MD, Maria Rita Pitari, PhD student, Nicola Amodio, PhD, Maria Teresa Di Martino, PhD, Emanuela Leone, PhD, Francesco Conforti, MD, Francesco Maria Paolino, PhD student, Cirino Botta, MD, Teresa Del Giudice, MD, Eleonora Iuliano, MD, Manlio Ferrarini, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2012) 120 (21): 3960.

https://doi.org/10.1182/blood.V120.21.3960.3960

Published: 2012

Journal Articles

MiR-34a Replacement As a Novel Therapeutic Approach for Multiple Myeloma: Preclinical In Vitro and In Vivo Evidence

Maria Teresa Di Martino, PhD, Emanuela Leone, PhD, Nicola Amodio, PhD, Umberto Foresta, PhD, Marta Lionetti, PhD, Maria Rita Pitari, PhD, Maria Eugenia Gallo Cantafio, PhD, Annamaria Gullà, Eugenio Morelli, MD, Marzia Leotta, Vera Tomaino, PhD, Marco Rossi, MD, Massimo Negrini, PhD, Manlio Ferrarini, MD, Antonino Neri, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2011) 118 (21): 2910.

https://doi.org/10.1182/blood.V118.21.2910.2910

Published: 2011

Journal Articles

SCID-Synth-Hu: a Novel Multiple Myeloma Model for In Vivo Expansion of Primary Cells

Teresa Calimeri, M.D., Edmondo Battista, Francesco Conforti, Paola Neri, MD, PhD, Maria Teresa Di Martino, Marco Rossi, Umberto Foresta, Eugenio Piro, Fiorenzo Ferrara, Andrea Amorosi, Nizar Bahlis, Kenneth C. Anderson, Nikhil C. Munshi, MD, Pierosandro Tagliaferri, Filippo Causa, Pierfrancesco Tassone

Blood (2010) 116 (21): 452.

https://doi.org/10.1182/blood.V116.21.452.452

Published: 2010

NARROW

A Novel Bispecific T Cell Engager (UMG2-BTCE) Targeting CD1a-CD3ε Is Effective Against Cortical-Derived Acute Lymphoblastic Leukemia

Global Rnaseq/Proteomic-Phoshoproteomic Analysis Unveil Mir-21 As a Central Player in Driving Th17 Mediated Bone Disease in MM

PARP1-Mediated Alt-NHEJ Repair Is a Therapeutic Target in Multiple Myeloma

Functional Role of Linc-RNAs in Multiple Myeloma: Linc-MIR17HG Affects Fatty Acid Biosynthesis Via transcriptional Regulation of ACC1 with Potential Therapeutic Implications

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92

Th17 Cells Targeting By MiR-21 Inhibitor Impairs Multiple Myeloma Related Bone Disease

Growth Inhibition and Synergistic Induction of Apoptosis By Synthetic Mir-125b-5p Mimics and Myc-Targeting Agents in Human Myeloma Cell Lines

Pharmacokinetics and Biodistribution of Locked Nucleic Acid (LNA)-Mir-221 Inhibitor: A New Promising Anti-Myeloma Agent

Selective Activation of the Non-Classical Estrogen Receptor Gper Elicits Potent Anti-Tumor Activity in Multiple Myeloma

MiR-29b Counteracts Aberrant HDAC4 Expression and Enhances Vorinostat Activity in Multiple Myeloma

Selective G-Protein Estrogen Receptor (GPER) Activation Triggers Anti-Multiple Myeloma Activity and Synergizes with MiR-29b-Inducing Drugs

Synthetic MiR-29b Mimics Potentiate Dendritic-Cell Based Immunotherapy Against Multiple Myeloma In Vitro and In Vivo

Tumor Suppressor MiR-29b Targets HDAC4 and Modulates Vorinostat Activity In Multiple Myeloma Cells

In Vitro and Vivo Activity Against Multiple Myeloma Cells Of a Novel Locked Nucleic Acid (LNA)-Mir-221 Inhibitor

Inhibition Of Mir-21 In HS-5 Bone Marrow Stromal Cells In The Presence Of Multiple Myeloma cells Restores RANKL/OPG Ratio: A Potential Therapeutic Approach For Myeloma-Related Bone Disease

MiR-29b Exerts Anti-Multiple Myeloma Activity by Targeting Key Oncogenic Pathways and Modulating DNA Methylation Profile.

Mir-29b Negatively Regulates Osteoclastic Cell Differentiation and Function: Implications for the Treatment of Multiple Myeloma-Related Bone Disease

MiR-34a Replacement As a Novel Therapeutic Approach for Multiple Myeloma: Preclinical In Vitro and In Vivo Evidence

SCID-Synth-Hu: a Novel Multiple Myeloma Model for In Vivo Expansion of Primary Cells

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American Society of Hematology

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