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Journal Articles

Unraveling Long-Term Survival of Multiple Myeloma Patients, the GEM2000 Experience

Rafael Alonso Fernandez, Andrés Arroyo Barea, Maria Teresa Cedena Romero, Laura Rosiñol Dachs, Javier de la Rubia, Sara Miqueleiz, Veronica Gonzalez-Calle, Felipe De Arriba, Luis Felipe Casado Montero, Miguel Teodoro Hernandez, Maria Mas Esteve, Pascual Fernandez, Paula Rodríguez-Otero, Carmen Calle Primo, Eugenia Abella, Paz Ribas, Adrian Alegre, Juan Miguel Bergua, Irene Gomez-Catalan, Jose Maria Arguiñano Perez, Luis Palomera, Enrique M Ocio, Maria Jose Busto Medina, Nieves Somolinos, Jose Maria Alonso Alonso, Aránzazu García Mateo, Joan Bargay, Pilar Delgado, Dunia De Miguel Llorente, Javier de la Cruz, Maria Victoria Mateos, Jesús F. San-Miguel, Joan Bladé, Juan-Jose Lahuerta Palacios, Joaquin Martinez Lopez
Journal: Blood
Blood (2024) 144 (Supplement 1): 1957.
https://doi.org/10.1182/blood-2024-211383
Published: 2024
Journal Articles

Enhancing CAR-T Cell Therapy for Non-Hodgkin Lymphoma through Gut Microbiota and Butyrate

Roberto Garcia-Vicente, Alba Rodríguez García, Raquel Ancos-Pintado, Andrés Arroyo Barea, Adriana Ortega-Hernandez, Irene Bragado-Garcia, Eva Castellano, Alejandra Ortiz-Ruiz, Miguel Angel Navarro-Aguadero, Javier Modrego, Alejandra Leivas, José Sanchez-Pina, Rafael Alonso Fernandez, Maria Hernandez-Sanchez, Mariateresa Fulciniti, Cecilia Carpio, Pere Barba, Diego Carbonell, Mi Kwon, Mariana Bastos-Oreiro, Alejandro Martín García-Sancho, Ana Jiménez Ubieto, Antonio Valeri, Dulcenombre Gomez-Garre, Joaquín Martínez-Lopez, María Linares
Journal: Blood
Blood (2024) 144 (Supplement 1): 3414.
https://doi.org/10.1182/blood-2024-205005
Published: 2024
Journal Articles

CRISPR/Cas9 Multi-Editing Enhances CAR NK Cells Therapeutic Potential Against Multiple Myeloma

Eva Castellano, Almudena García-Ortiz, Laura Ugalde, Elena Maroto Martin, Jessica Encinas Mayoral, Raquel Oliva, Laura Garcia-Garcia, Irene Peña, Noemi Álvarez, Gonzalo Carreño, Rosa Ayala, Laura Cordoba, Alejandra Leivas, Guillermo Suñe, Beatriz Martin Antonio, Rafael Alonso Fernandez, Maria Teresa Cedena Romero, Joaquín Martínez-Lopez, Paula Rio, Antonio Valeri
Journal: Blood
Blood (2024) 144 (Supplement 1): 3442.
https://doi.org/10.1182/blood-2024-207942
Published: 2024
Journal Articles

Epigenetic Modifications As a Mechanism of Resistance to BCMA-Directed Immunotherapies in Multiple Myeloma: Insights from Multi-Omic Profiling

Larissa Haertle, Natalia Buenache Cuenda, Isabel Espejo Diaz, Paula Lázaro Del Campo, Andres Arroyo-Barea, Leonie Rieger, Juan Manuel Rosa-Rosa, Rafael Alonso Fernandez, Nieves Lopez, José Sanchez-Pina, Almudena García-Ortiz, Antonio Valeri, Santiago Barrio, Fatima Al-Shahrour, Florian Bassermann, Joaquin Martínez-López, Tomas Di Domenico
Journal: Blood
Blood (2024) 144 (Supplement 1): 5794.
https://doi.org/10.1182/blood-2024-198117
Published: 2024
Journal Articles

Real-Life Experience of the Combination of Daratumumab, Bortezomib, Melphalan, and Prednisone (DVMP) in Patients with Newly Diagnosed Multiple Myeloma Ineligible for Autologous Stem-Cell Transplantation

Amalia Domingo-González, Rafael Alonso Fernández, Ana Jiménez, Teresa De Soto Alvarez, Ana Lerma, Virginia Pradillo Fernandez, Gonzalo Benzo Callejo, Jose Sanchez-Pina, Elena Landete, Alberto Velasco, Marina Menéndez Cuevas, Mónica María López Riñón, Andrés Ramírez López, Alberto Lopez Garcia, María-Jesús Blanchard, Elham Askari
Journal: Blood
Blood (2023) 142 (Supplement 1): 4745.
https://doi.org/10.1182/blood-2023-186954
Published: 2023
Journal Articles

Sustained Recovery of Uninvolved Heavy/Light Chain Pair Immunoparesis during Maintenance Discriminates Patients with Sustained Negative Minimal Residual Disease

Sunil Lakhwani, Laura Rosiñol, Noemi Puig, Miguel Angel Pico Picos, Laura Medina-González, Joaquin Martinez Lopez, Bruno Paiva, Maria Teresa Cedena Romero, Albert Oriol, Rafael Ríos, María Jesús Blanchard, Isidro Jarque, Joan Bargay, Jose Maria Moraleda, Estrella Carrillo-Cruz, Anna Maria Sureda Balari, Isabel Krsnik, Esther Gonzalez Garcia, Luis Felipe Casado Montero, Josep Maria Marti Tutusaus, Cristina Encinas Rodriguez, Felipe De Arriba, Luis Palomera, Antonia Sampol Mayol, Yolanda González-Montes, Cristina Motlló, Javier De la Cruz, Rafael Alonso Fernández, Maria-Victoria Mateos, Joan Blade Creixenti, Juan Jose Lahuerta Palacios, Jesus San Miguel, Miguel Teodoro Hernández Garcia
Journal: Blood
Blood (2023) 142 (Supplement 1): 1958.
https://doi.org/10.1182/blood-2023-179452
Published: 2023
Journal Articles

Large Scale Analysis of Autologous Stem Cell Transplantation for Multiple Myeloma Patients Older Than 65 Years

Adolfo Jesús Sáez Marín, Gema Hernández-Ibarburu, Rafael Alonso Fernández, Jose Maria Sanchez Pina, Paula Lázaro Del Campo, Ana Jimenez Ubieto, Clara Cuellar, Andrea Tamayo Soto, Reyes Mas Babio, Lucia Medina, Maria Calbacho, Rosa Ayala, Joaquin Martinez Lopez
Journal: Blood
Blood (2023) 142 (Supplement 1): 7064.
https://doi.org/10.1182/blood-2023-180923
Published: 2023
Journal Articles

Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma Included in the Compassionate Use or the Expanded Access Program. Experience with a Spanish Cohort

Javier De La Rubia, Rafael Alonso, Maria Esther Clavero Sanchez, Elham Askari, Alfonso García de Coca, Ana Maldonado, Margarita Fernandez De La Mata, Fernando Escalante, Ana Garcia-Feria, Rafael Rios, Venancio Conesa, Maria Aranzazu Bermudez, Beatriz Merchan, Alberto Velasco, María Jesús Blanchard, Antonia Sampol, Eukene Gainza González, Pedro M Hernandez, Veronica Gonzalez-Calle, Adrian Alegre
Journal: Blood
Blood (2022) 140 (Supplement 1): 4315–4317.
https://doi.org/10.1182/blood-2022-158538
Published: 2022
Journal Articles

Recovery of Uninvolved Heavy/Light Chain Pair Immunoparesis during Maintenance Is an Independent Prognostic Factor for Multiple Myeloma and Could Complement Prognosis Value of Minimal Residual Disease

Sunil Lakhwani, Laura Rosinol Dachs, Noemi Puig, Miguel Angel Pico Picos, Laura Medina-González, Joaquín Martínez-López, Bruno Paiva, Albert Oriol, Rafael Rios, María Jesús Blanchard, Isidro Jarque, Joan Bargay, Jose Maria Moraleda, Estrella Carrillo-Cruz, Anna Sureda, Isabel Krsnik, Esther González Garcia, Luis Felipe Casado Montero, Josep M Marti, Cristina Encinas, Felipe De Arriba, Luis Palomera, Antonia Sampol, Yolanda Gonzalez-Montes, Cristina Motllo, Javier De La Cruz, Rafael Alonso Fernández, María-Victoria Mateos, Joan Bladé Creixenti, Juan-José Lahuerta, Jesús San-Miguel, Miguel-Teodoro Hernández
Journal: Blood
Blood (2022) 140 (Supplement 1): 2101–2103.
https://doi.org/10.1182/blood-2022-167247
Published: 2022
Journal Articles

Triple Combination of Ruxolutinib, Nilotinib and Prednisone Is Safe and Shows Promising Activity for the Treatment of Myelofibrosis Patients, Results of a Phase Ib Clinical Trial (RUNIC)

Rosa Ayala, Rafael Alonso Fernández, Valentín Garcia Gutierrez, Alberto Alvarez-Larran, Santiago Osorio, Jose M. Sanchez, Gonzalo Carreño Gomez-Tarragona, María Teresa Gómez-Casares, Antonia Duran, Joaquín Martínez-López
Journal: Blood
Blood (2021) 138 (Supplement 1): 3655.
https://doi.org/10.1182/blood-2021-150240
Published: 2021
Journal Articles

Compassionate Use of Belantamab Mafodotin for Treatment of Patients with Relapsed/Refractory Multiple Myeloma Heavily Treated. Spanish Experience

Adrian Alegre, Gonzalo Benzo Callejo, Rafael Alonso Fernández, Joaquin Martínez-López, Ana Jimenez-Ubieto, Clara Cuellar, Elham Askari, Elena Prieto, Concha Alaez, Beatriz Aguado, Alberto Velasco, Isabel Krsnik, Laura Llorente, Cristina Muñoz-Linares, Ana Morales, Eugenio Gimenez Mesa, Rebeca Iglesias, Carmen Martínez-Chamorro, Arancha Alonso, Carmen Jiménez-Montes, María Jesús Blanchard
Journal: Blood
Blood (2021) 138 (Supplement 1): 3775.
https://doi.org/10.1182/blood-2021-151267
Published: 2021
Journal Articles

Cereblon enhancer methylation and IMiD resistance in multiple myeloma

Clinical Trials & Observations Brief Report
Larissa Haertle, Santiago Barrio, Umair Munawar, Seungbin Han, Xiang Zhou, Cornelia Vogt, Rafael Alonso Fernández, Max Bittrich, Yanira Ruiz-Heredia, Matteo Da Viá, Josip Zovko, Andoni Garitano-Trojaola, Niccolò Bolli, Anna Ruckdeschel, Thorsten Stühmer, Manik Chatterjee, Miriam Kull, Jan Krönke, Xabier Agirre, Jose I. Martin-Subero, Peter Raab, Hermann Einsele, Leo Rasche, Joaquin Martinez-Lopez, Thomas Haaf, K. Martin Kortüm
Journal: Blood
Blood (2021) 138 (18): 1721–1726.
https://doi.org/10.1182/blood.2020010452
Published: 2021
Includes: Supplemental data
Journal Articles

Making Clinical Decisions to Change Therapy Using Measurable Residual Disease Improves the Outcome in Multiple Myeloma

Joaquin Martinez Lopez, Rafael Alonso Fernández, Sandy W. Wong, MD, Rafael Rios, MD PhD, Nina Shah, MD, Maria Teresa Cedena Romero, MD PhD, Yanira Ruiz-Heredia, Jose M. Sanchez, MD, Santiago Barrio Garcia, PhD, Thomas Martin, III, MD, Jeffrey L. Wolf, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–43.
https://doi.org/10.1182/blood-2020-140352
Published: 2020
Journal Articles

Enhancing the Immune Surveillance in Multiple Myeloma Via CDK4/6 Inhibition

Yan Xu, MD, Yao Yao, Woojun Daniel Park, Sanika Derebail, MS, Chandraditya Chakraborty, PhD, Shidai Mu, Rafael Alonso Fernández, Srikanth Talluri, PhD, Zuzana Chyra, PhD, Kenneth Wen, Qingsheng Yan, Osasenaga Idahor, Selene Cipri, Rao Prabhala, Kenneth Anderson, MD, Mehmet K. Samur, PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-143327
Published: 2020
Journal Articles

YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma

Yan Xu, Mariateresa Fulciniti, Mehmet K. Samur, Matthew Ho, Shuhui Deng, Lanting Liu, Kenneth Wen, Tengteng Yu, Zuzana Chyra, Sanika Dereibal, Li Zhang, Yao Yao, Chandraditya Chakraborty, Eugenio Morelli, Na Li, Michael A. Lopez, Tommaso Perini, Shidai Mu, Gang An, Rafael Alonso, Giada Bianchi, Yu-Tzu Tai, Kenneth C. Anderson, Lugui Qiu, Nikhil C. Munshi
Journal: Blood
Blood (2020) 136 (4): 468–479.
https://doi.org/10.1182/blood.2019004147
Published: 2020
Includes: Supplemental data
Journal Articles

Restoring Innate and Adaptive Immune Repertoire in Multiple Myeloma for Therapeutic Application

Rafael Alonso Fernández, MD, Laetitia Pierre-Louis, Rao Prabhala, Yan Xu, MD, Joaquin Martinez-Lopez, MD PhD, Takahiro Miyazaki, Mehmet Kemal Samur, PhD, Loui Madakamutil, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4398.
https://doi.org/10.1182/blood-2019-128767
Published: 2019
Journal Articles

The Role of Antiviral Treatment in Hepatitis C Virus (HCV)-Driven Monoclonal Gammopathies

Alba Rodríguez García, María Linares, PhD, Nicolas Mennesson, Alfredo Pérez-Revilla, Ricardo Sanchez, PhD MD, Alejandra Leivas, PhD BS, MSc, Rafael Alonso Fernández, MD, Edith Bigot-Corbel, PhD, Sylvie Hermouet, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5560.
https://doi.org/10.1182/blood-2019-126549
Published: 2019
Journal Articles

Immunofixation (IF) in Urine Is Really Necessary to Define Complete Remission in Multiple Myeloma (MM)? a Subanalysis from the Pethema/GEM2012MENOS65 Phase III Clinical Trial

Ana Jiménez Ubieto, MD PhD, Bruno Paiva, MD PhD, Joaquin Martínez-López, MD PhD, Laura Rosinol, MD PhD, Maria Teresa Cedena Romero, MD PhD, Maria Jose Calasanz, BSc, PhD, Noemi Puig, MD PhD, Ramon Garcia-Sanz, MD PhD, Norma C. Gutierrez, MD PhD, Maria Luisa Martin-Ramos, Albert Oriol, MD, José Gonzalez Medina, Rafael Alonso Fernandez, Jesús Blanchard, MD, Rafael Rios, MD PhD, Jesús Martín, Rafael Martinez Martinez, Josep Sarra, Miguel-Teodoro Hernández, Javier De La Rubia, MD, Isabel Krsnik, MD PhD, Jose Maria Moraleda, Luis Palomera, MD PhD, Maria-Victoria Mateos, MD PhD, Jesús F San-Miguel, MD, Joan Bladé, MD, Juan-José Lahuerta, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 474.
https://doi.org/10.1182/blood-2018-99-115050
Published: 2018
Journal Articles

The Role of Hepatitis C Virus in the Development of Multiple Myeloma: A Case Study

Alba Rodríguez García, María Linares, PhD, Nicolas Mennesson, Beatriz Sanchez-Vega, PhD, Ricardo Sanchez, Rafael Alonso Fernandez, Edith Bigot-Corbel, PhD, Sylvie Hermouet, Joaquin Martinez Lopez, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5592.
https://doi.org/10.1182/blood-2018-99-112842
Published: 2018
Journal Articles

Absence of Contribution to a Differential Outcome of the Stringent Complete Response IMWG Category Respect to the Conventional CR in Multiple Myeloma. a Validation Analysis Based on the Pethema/GEM2012MENOS65 Phase III Clinical Trial

Ana Jiménez Ubieto, MDPhD, Joaquin Martinez Lopez, MD PhD, Laura Rosinol, MD PhD, Bruno Paiva, MD PhD, María Teresa Cedena, Noemi Puig, MD PhD, Maria Jose Calasanz, BSc, PhD, José Gonzalez Medina, Maria Luisa Martin-Ramos, Rafael Alonso Fernandez, Albert Oriol, MD, Jesús Blanchard, MD, Enrique M. Ocio, MD, Javier De La Rubia, MD, Rafael Rios, MD PhD, Jesús Martín, Miguel-Teodoro Hernández, Isabel Krsnik, MD PhD, Jose Maria Moraleda, Luis Palomera, MD PhD, Joan Bargay, MD PhD, Maria-Victoria Mateos, MD PhD, Jesús F San-Miguel, MD, Joan Bladé, MD, Juan-José Lahuerta, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1943.
https://doi.org/10.1182/blood-2018-99-116604
Published: 2018