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Michael A. Lopez
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Journal Articles

YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma

Yan Xu, Mariateresa Fulciniti, Mehmet K. Samur, Matthew Ho, Shuhui Deng, Lanting Liu, Kenneth Wen, Tengteng Yu, Zuzana Chyra, Sanika Dereibal, Li Zhang, Yao Yao, Chandraditya Chakraborty, Eugenio Morelli, Na Li, Michael A. Lopez, Tommaso Perini, Shidai Mu, Gang An, Rafael Alonso, Giada Bianchi, Yu-Tzu Tai, Kenneth C. Anderson, Lugui Qiu, Nikhil C. Munshi
Journal: Blood
Blood (2020) 136 (4): 468–479.
https://doi.org/10.1182/blood.2019004147
Published: 2020
Includes: Supplemental data
Journal Articles

Favorable Progression-Free Survival Associated with Immune Bio-Markers Modulated By Pomalidomide in Relapsed/Refractory Multiple Myeloma: An Analysis of Phase III Study

Rao Prabhala, PhD, Mehmet Kemal Samur, PhD, Srikanth Talluri, PhD, Megan Stekla, BS, Chaitanya Yenumula, MD, Michael A Lopez, Sanika Derebail, Lakshmi B. Potluri, Angela Wang, Aishwarya Katiki, Sahan D. Vangala, Eric Haas, Michael J Buonopane, BS, Alexander T Heubeck, BS, Mariateresa Fulciniti, PhD, Raphael Szalat, MD, Suzan Lazo-Kallanian, BS, Kevin Hong, Teresa Peluso, John Daley, PhD, Tsvetan Biyukov, MD, Albert Oriol, William E. Pierceall, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Anjan Thakurta, Hervé Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1784.
https://doi.org/10.1182/blood-2019-131257
Published: 2019
Journal Articles

Genome Wide Transcriptomic Analysis Identifies Dysregulated Splicing Factor Profile with Molecular and Functional Role in Multiple Myeloma

Anil Aktas Samur, PhD, Mehmet Kemal Samur, PhD, Michael A Lopez, Sanika Derebail, Kenneth C. Anderson, MD, Herve Avet-Loiseau, MD PhD, Giovanni Parmigiani, PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 361.
https://doi.org/10.1182/blood-2019-129114
Published: 2019
Journal Articles

Inhibitor of DNA Binding 2 (ID2) Plays a Key Tumor Suppressor Role in Promoting Oncogenic Transformation in Multiple Myeloma

Tommaso Perini, MD, Raphael Szalat, MD, Mehmet Kemal Samur, PhD, Mariateresa Fulciniti, PhD, Michael A Lopez, Matthew Lawlor, Christopher J. Ott, PhD, Na Li, MD, Yan Xu, MD, Kenneth Wen, BS, Nicola Amodio, PhD, Eugenio Morelli, MD, Kenneth Anderson, MD, Fabio Ciceri, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 60.
https://doi.org/10.1182/blood-2018-99-118401
Published: 2018
Journal Articles

Dysregulation of Splicing in Multiple Myeloma: The Splicing Factor SRSF1 Supports MM Cell Proliferation Via Splicing Control

Mariateresa Fulciniti, PhD, Michael A Lopez, Anil Aktas Samur, PhD, Eugenio Morelli, MD, Hervé Avet-Loiseau, MD PhD, Mehmet Kemal Samur, PhD, Nikhil Munshi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4500.
https://doi.org/10.1182/blood-2018-99-118845
Published: 2018
Journal Articles

Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

Mehmet Kemal Samur, PhD, Chandraditya Chakraborty, PhD, Raphael Szalat, MD, Anil Aktas Samur, PhD, Mariateresa Fulciniti, PhD, Michael A Lopez, Masood A. Shammas, PhD, Paul Richardson, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Philippe Moreau, Michel Attal, Anjan Thakurta, PhD, Kenneth Anderson, MD, Giovanni Parmigiani, Hervé Avet-Loiseau, MDPhD, Nikhil Munshi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 190.
https://doi.org/10.1182/blood-2018-190
Published: 2018
Journal Articles

Functional Role of Linc-RNAs in Multiple Myeloma: Linc-MIR17HG Affects Fatty Acid Biosynthesis Via transcriptional Regulation of ACC1 with Potential Therapeutic Implications

Eugenio Morelli, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Francesca Scionti, Annamaria Gulla, MD, Nicola Amodio, PhD, Giada Bianchi, MD, Tommaso Perini, MD, Cinzia Federico, PhD, Michael A Lopez, Maria Teresa Di Martino, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD, Kenneth Anderson, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1925.
https://doi.org/10.1182/blood-2018-99-119572
Published: 2018
Journal Articles

Dysregulated Translational Control Is a Central Feature of MM Mediated By 14-3-3ε Interactome Promoting Multiple Myeloma Cell Growth and Viability

Yan Xu, MD, Mariateresa Fulciniti, PhD, Matthew Ho, Mehmet Kemal Samur, PhD, Michael A Lopez, Na Li, MD, Giada Bianchi, MD, Raphael Szalat, MD, Jianhong Lin, MD MSc, Tommaso Perini, MD, Srikanth Talluri, PhD, Tengteng Yu, MD, Kenneth Wen, BS, Jiye Liu, PhD, Li Zhang, MD, Liang Lin, PhD, Lijie Xing, MD, Gang An, MD, Yu-Tzu Tai, PhD, Kenneth Anderson, MD, Lugui Qiu, MD PhD, Nikhil Munshi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3176.
https://doi.org/10.1182/blood-2018-99-118994
Published: 2018
Journal Articles

Bone Marrow Microenvironment Induces Genomic Instability and Enables Clonal Evolution in Multiple Myeloma

Tommaso Perini, MD, Raphael Szalat, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Michael A Lopez, BS, Puru Nanjappa, Kenneth Wen, BS, Na Li, MD, Yan Xu, MD, Yu-Tzu Tai, PhD, Masood A. Shammas, PhD, Kenneth C Anderson, MD, Fabio Ciceri, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4408.
https://doi.org/10.1182/blood.V130.Suppl_1.4408.4408
Published: 2017
Journal Articles

Mapping of the Multiple Myeloma Transcriptional Core Regulatory Circuitry Reveals TCF3 As a Novel Dependency and an Oncogenic Collaborator of MYC

Charles Y Lin, PhD, Mariateresa Fulciniti, PhD, Michael A Lopez, BS, Mehmet Kemal Samur, PhD, Raphael Szalat, MD, Christopher J. Ott, PhD, Charles Epstein, Richard A. Young, PhD, James Bradner, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 64.
https://doi.org/10.1182/blood.V130.Suppl_1.64.64
Published: 2017
Journal Articles

PAK4 Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldestrostom Macroglobulinemia

Na Li, MD, Mariateresa Fulciniti, PhD, Michael A Lopez, BS, Tommaso Perini, MD, Raphael Szalat, MD, Subodh Kumar, PhD, Mehmet Kemal Samur, PhD, Lian Xu, Yan Xu, MD, William Senapedis, PhD, Erkan Baloglu, Stefania Oliva, MD, Masood A. Shammas, PhD, Zachary Hunter, PhD, Kenneth C Anderson, MD, Steven P Treon, MDPhDFRCP, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 648.
https://doi.org/10.1182/blood.V130.Suppl_1.648.648
Published: 2017
Journal Articles

Perturbation in B Cell-Subsets Can Explain the Observed Suppression of Uninvolved Immunoglobulins and Their Impact on T Tell-Subsets As Well As Patients Outcome in Myeloma

Rao Prabhala, PhD, Shree Acharya, MS, Megan Stekla, BS, Srikanth Talluri, PhD, Raphael Szalat, MD, Puru Nanjappa, Michael A Lopez, BS, Kenneth Wen, BS, Chaitanya Yenumula, MD, Alexander Heubeck, BS, Yu-Tzu Tai, PhD, Ansh Mehta, MBBS, Mariateresa Fulciniti, PhD, Suzan Lazo-Kallanian, BS, John Daley, PhD, Paul G Richardson, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3049.
https://doi.org/10.1182/blood.V130.Suppl_1.3049.3049
Published: 2017
Journal Articles

Ywhae Located on Chromosome 17p13 Promotes Myeloma Cells Proliferation Via Induction of Anti-Apoptosis and Survival Signaling Pathways

Yan Xu, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Raphael Szalat, MD, Matthew Ho, Michael A Lopez, BS, Na Li, MD, Jianhong Lin, MD MSc, Tommaso Perini, MD, Srikanth Talluri, PhD, Jiye Liu, PhD, Kenneth Wen, BS, Giada Bianchi, MD, Li Zhang, MD, Lijie Xing, MD, An Gang, MD, Liang Lin, PhD, Yu-Tzu Tai, PhD, Lugui Qiu, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1755.
https://doi.org/10.1182/blood.V130.Suppl_1.1755.1755
Published: 2017