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Journal Articles

Upregulation of BCMA expression by selinexor

Christina Verbruggen, Umair Munawar, Seungbin Han, Julia Mersi, Emma Besant, Shilpa Kurian, Silvia Nerreter, Nina Rein, Johanna Lehmann, Max Koeppel, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2025) 146 (Supplement 1): 6102.

https://doi.org/10.1182/blood-2025-6102

Published: 2025

Journal Articles

Plasmapheresis facilitates soluble BCMA clearance and contributes to reversing primary resistance to anti-BCMA immunotherapy in multiple myeloma

Blood (2025) 146 (Supplement 1): 7465.

https://doi.org/10.1182/blood-2025-7465

Published: 2025

Journal Articles

NQO1 modulates CD38 surface expression in multiple myeloma

Seungbin Han, Christina Verbruggen, Silvia Nerreter, Umair Munawar, Shilpa Kurian, Emma Besant, Ann-Sophie Hainold, Cornelia Vogt, Xiang Zhou, Hermann Einsele, Leo Rasche, Markus Sauer, Johannes Waldschmidt, K. Martin Kortüm

Blood (2025) 146 (Supplement 1): 5718.

https://doi.org/10.1182/blood-2025-5718

Published: 2025

Journal Articles

Talquetamab alters T cell transcriptome in presence of GPRC5D on MM cells

Umair Munawar, Alexander Leipold, Silvia Nerreter, Seungbin Han, Shilpa Kurian, Emma Besant, Nina Rein, Max Koeppel, Johanna Lehmann, Xiang Zhou, Hermann Einsele, Leo Rasche, Emmanuel Saliba, Johannes Waldschmidt, K. Martin Kortüm

Blood (2025) 146 (Supplement 1): 5701.

https://doi.org/10.1182/blood-2025-5701

Published: 2025

Journal Articles

Lattice light-sheet microscopy reveals patient specific responses to CD20-directed antibodies in B cell malignancies

Julia Weingart, Patrick Eiring, Umair Munawar, Seungbin Han, Christina Verbruggen, Silvia Nerreter, Shilpa Kurian, Max Steinhardt, Leo Rasche, Hermann Einsele, Johannes Waldschmidt, K. Martin Kortüm, Markus Sauer

Blood (2025) 146 (Supplement 1): 4343.

https://doi.org/10.1182/blood-2025-4343

Published: 2025

Journal Articles

Modeling of a hyper-inflammatory hematopoietic niche ex vivo reveals a multi-step process driving CAR T- cell associated myeloid leukemia in multiple myeloma

Blood (2025) 146 (Supplement 1): 2152.

https://doi.org/10.1182/blood-2025-2152

Published: 2025

Journal Articles

Tumor intrinsic mechanisms leading to cevostamab resistance in multiple myeloma

Blood (2025) 146 (Supplement 1): 2178.

https://doi.org/10.1182/blood-2025-2178

Published: 2025

Journal Articles

Impact of bortezomib on T-cell subsets and immune checkpoints under bispecific antibody therapy in multiple myeloma

Xiang Zhou, Umair Munawar, Shilpa Kurian, Seungbin Han, Mara John, Hanna Fischer, Silvia Nerreter, Lenka Besse, Andrej Besse, Christoph Driessen, Marc Schmalzing, Johannes Waldschmidt, Hermann Einsele, Leo Rasche, K. Martin Kortüm

Blood (2025) 146 (Supplement 1): 2174.

https://doi.org/10.1182/blood-2025-2174

Published: 2025

Journal Articles

Novel insights in therapeutic antibody therapies using advanced microscopy techniques

Christina Verbruggen, Patrick Eiring, Max Steinhardt, Julia Weingart, Umair Munawar, Seungbin Han, Sven Neubert, Emma Besant, Cornelia Vogt, Silvia Nerreter, Shilpa Kurian, Nina Rein, Johanna Lehmann, Max Koeppel, Hermann Einsele, Johannes Waldschmidt, Markus Sauer, K. Martin Kortüm

Blood (2025) 146 (Supplement 1): 6111.

https://doi.org/10.1182/blood-2025-6111

Published: 2025

Journal Articles

Elevated NQO1 expression mediates proteasome inhibitor resistance and predicts adverse outcomes in multiple myeloma

Blood (2025) 146 (Supplement 1): 6812.

https://doi.org/10.1182/blood-2025-6812

Published: 2025

Journal Articles

Implementing Hifi Sequencing for Enhanced Genomic and Methylome Characterization in Multiple Myeloma

Seungbin Han, Nazia Afrin, Bas Tolhuis, Marietta Truger, Peter Raab, Umair Munawar, Cornelia Vogt, Shilpa Kurian, Silvia Nerreter, Xiang Zhou, Claudia Haferlach, Hermann Einsele, Johannes Waldschmidt, Leo Rasche, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 7490.

https://doi.org/10.1182/blood-2024-207422

Published: 2024

Journal Articles

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Seungbin Han, Chien-Yun Lee, Lenka Besse, Umair Munawar, Andrej Besse, Ann-Sohpie Hainold, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Xiang Zhou, Larissa Haertle, Johannes Waldschmidt, Christoph Driessen, Hermann Einsele, Leo Rasche, Bernhard Kuster, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 6817.

https://doi.org/10.1182/blood-2024-203352

Published: 2024

Journal Articles

Classic Anti-Myeloma Treatments Alter Circulating Immune Cell Subsets with Potential Implications for T Cell Immunotherapies in Multiple Myeloma

Xiang Zhou, Sarah Wiethe, Angelika Wolff, Max J Steinhardt, Nazia Afrin, Mara John, Christine Riedhammer, Xianghui Xiao, Umair Munawar, Julia Mersi, Seungbin Han, Johannes Waldschmidt, Angela Riedel, Max S. Topp, Johannes Duell, Hermann Einsele, K. Martin Kortüm, Leo Rasche

Blood (2024) 144 (Supplement 1): 4705.

https://doi.org/10.1182/blood-2024-203391

Published: 2024

Journal Articles

Bi-Allelic GPRC5D Alterations Provide Proliferative Advantage in Presence of Talquetamab

Umair Munawar, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Patrick Eiring, Julia Weingart, Xiang Zhou, Markus Sauer, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 593.

https://doi.org/10.1182/blood-2024-200593

Published: 2024

Journal Articles

GPRC5D Status Impacts CD38 Expression in Multiple Myeloma

Umair Munawar, Julia Weingart, Patrick Eiring, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Seungbin Han, Max J Steinhardt, Xiang Zhou, Markus Sauer, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 3267.

https://doi.org/10.1182/blood-2024-204863

Published: 2024

Journal Articles

Clinical and Diagnostic Challenges in Patients with Concomitant Plasma Cell Disorders and Myeloproliferative Neoplasms

Maximilian J Steinhardt, Thomas Bumm, Xiang Zhou, Umair Munawar, Seungbin Han, Julia Mersi, Hermann Einsele, Leo Rasche, K. Martin Kortüm, Johannes M Waldschmidt

Blood (2023) 142 (Supplement 1): 6771.

https://doi.org/10.1182/blood-2023-189528

Published: 2023

Journal Articles

Safety and Efficacy of Venetoclax Salvage Therapy in Relapsed/Refractory Multiple Myeloma with and without t(11;14)

Maximilian J Steinhardt, Max Bittrich, Xiang Zhou, Julia Noderer, Christine Riedhammer, Xianghui Xiao, Sophia Gawlas, Philipp Weis, Florian Eisele, Umair Munawar, Seungbin Han, Julia Mersi, Johannes M Waldschmidt, Hermann Einsele, Leo Rasche, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 6702.

https://doi.org/10.1182/blood-2023-189927

Published: 2023

Journal Articles

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Seungbin Han, Umair Munawar, Larissa Haertle, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Xiang Zhou, Max Steinhardt, Florian Eisele, Peter Raab, Marietta Truger, Sara Dorado, Santiago Barrio, Claudia Haferlach, Joaquin Martínez-López, Hermann Einsele, Leo Rasche, Johannes M Waldschmidt, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 3323.

https://doi.org/10.1182/blood-2023-181607

Published: 2023

Journal Articles

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Maximilian J Steinhardt, Patrick Eiring, Cornelia Vogt, Umair Munawar, Seungbin Han, Larissa Haertle, Silvia Nerreter, Eva Teufel, Julia Mersi, Xiang Zhou, Michael Hudecek, Joaquin Martinez-Lopez, Johannes M Waldschmidt, Hermann Einsele, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 1992.

https://doi.org/10.1182/blood-2023-189741

Published: 2023

Journal Articles

Bone Marrow Plasma Cell Infiltration Is a Prognostic Factor for Response to AL Amyloidosis Therapy

Maximilian J Steinhardt, Vladimir Cejka, Caroline Morbach, Aikaterini Papagianni, Silvia Nerreter, Cornelia Vogt, Umair Munawar, Seungbin Han, Leo Rasche, Johannes M Waldschmidt, Claudia Sommer, Stefan Störk, Hermann Einsele, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 6753.

https://doi.org/10.1182/blood-2023-189326

Published: 2023

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Upregulation of BCMA expression by selinexor

Plasmapheresis facilitates soluble BCMA clearance and contributes to reversing primary resistance to anti-BCMA immunotherapy in multiple myeloma

NQO1 modulates CD38 surface expression in multiple myeloma

Talquetamab alters T cell transcriptome in presence of GPRC5D on MM cells

Lattice light-sheet microscopy reveals patient specific responses to CD20-directed antibodies in B cell malignancies

Modeling of a hyper-inflammatory hematopoietic niche ex vivo reveals a multi-step process driving CAR T- cell associated myeloid leukemia in multiple myeloma

Tumor intrinsic mechanisms leading to cevostamab resistance in multiple myeloma

Impact of bortezomib on T-cell subsets and immune checkpoints under bispecific antibody therapy in multiple myeloma

Novel insights in therapeutic antibody therapies using advanced microscopy techniques

Elevated NQO1 expression mediates proteasome inhibitor resistance and predicts adverse outcomes in multiple myeloma

Implementing Hifi Sequencing for Enhanced Genomic and Methylome Characterization in Multiple Myeloma

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Classic Anti-Myeloma Treatments Alter Circulating Immune Cell Subsets with Potential Implications for T Cell Immunotherapies in Multiple Myeloma

Bi-Allelic GPRC5D Alterations Provide Proliferative Advantage in Presence of Talquetamab

GPRC5D Status Impacts CD38 Expression in Multiple Myeloma

Clinical and Diagnostic Challenges in Patients with Concomitant Plasma Cell Disorders and Myeloproliferative Neoplasms

Safety and Efficacy of Venetoclax Salvage Therapy in Relapsed/Refractory Multiple Myeloma with and without t(11;14)

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Bone Marrow Plasma Cell Infiltration Is a Prognostic Factor for Response to AL Amyloidosis Therapy

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American Society of Hematology

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