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Journal Articles

Anti-TIM3 with hypomethylating agent revives NK and cytotoxic CD4+ T cell activity in patients with AML or MDS

Blood (2025) 146 (Supplement 1): 1704.

https://doi.org/10.1182/blood-2025-1704

Published: 2025

Journal Articles

Modeling of a hyper-inflammatory hematopoietic niche ex vivo reveals a multi-step process driving CAR T- cell associated myeloid leukemia in multiple myeloma

Blood (2025) 146 (Supplement 1): 2152.

https://doi.org/10.1182/blood-2025-2152

Published: 2025

Journal Articles

A randomized study of ropeginterferon in combination with bosutinib in newly diagnosed chronic myeloid leukemia (CML) patients in chronic Phase. the bosupeg trial from the Nordic CML study group

Blood (2025) 146 (Supplement 1): 3780.

https://doi.org/10.1182/blood-2025-3780

Published: 2025

Journal Articles

Tracing the evolution of clonal T cell responses in LGL leukemia with single-cell whole genome sequencing

Aino Häkkinen, Sofia Forstén, Sofie Lundgren, Mikko Keränen, Laurianne Trabut, Mark Verheul, Markus Van Roosmalen, Jani Huuhtanen, Ruben Van Boxtel, Satu Mustjoki

Blood (2025) 146 (Supplement 1): 3523.

https://doi.org/10.1182/blood-2025-3523

Published: 2025

Journal Articles

High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia

Petra Nygrén, Jonas Bouhlal, Emmi Jokinen, Sofia Forstén, Essi Laajala, Diogo Dias, Shady Adnan-Awad, Aleksandr Ianevski, Jay Klievink, Hanna Lähteenmäki, Heikki Kuusanmäki, Mikko Myllymäki, Tiina Kasanen, Khalid Saeed, Dean A. Lee, Henrik Hjorth-Hansen, Tero Aittokallio, Olli Dufva, Satu Mustjoki

Blood (2025) 145 (15): 1670–1686.

https://doi.org/10.1182/blood.2024025286

Published: 2025

Includes: Supplemental data

Journal Articles

Predicting Antigen-Specific T Cell Immunity Against Wilms Tumor 1 in Hematologic Cancer

Emmi Jokinen, Brittany Ford, Jani Huuhtanen, Sofia Forstén, Jay Klievink, Gabriella Antignani, Oscar E. Brück, Vincenzo Cerullo, Karita Peltonen, Satu Mustjoki

Blood (2024) 144 (Supplement 1): 3596.

https://doi.org/10.1182/blood-2024-205072

Published: 2024

Journal Articles

Bone Marrow Stromal Cells Hamper Leukemia Cell Induced NK Cell Activation and Cytotoxicity

Salomé Decombis, Johannes Smolander, Jonas Bouhlal, Jay Klievink, Hanna Lähteenmäki, Emmi Jokinen, Linh Lin, Hanna Laitinen, Konstantin Matjusinski, Eveliina Holappa, Mikko Myllymäki, Heidi Haikala, Sara Gandolfi, Satu Mustjoki

Blood (2024) 144 (Supplement 1): 4814.

https://doi.org/10.1182/blood-2024-202959

Published: 2024

Journal Articles

Computational Cytomorphological Analyses Identifies Bone Marrow Erythroblast Proportion As a Biomarker of Treatment-Free Remission in CML

Mikko Purhonen, Mikael Tatun, Kevin Hung, Oda Tafjord, Shady Adnan-Awad, Perttu Koskenvesa, Sanna Siitonen, Kimmo Porkka, Satu Mustjoki, Signe Danielsson, Henrik Hjorth-Hansen, Ulla Olsson-Strömberg, Takashi Kumagai, Shinya Kimura, David M Ross, Oscar E. Brück

Blood (2024) 144 (Supplement 1): 1780.

https://doi.org/10.1182/blood-2024-207253

Published: 2024

Journal Articles

Genomic Subtypes of AML Define Sensitivity to NK Cell Cytotoxicity

Hanna Duàn, Emmi Jokinen, Hanna Lähteenmäki, Jay Klievink, Jonas Bouhlal, Essi Laajala, Jason Theodoropoulos, Heikki Kuusanmäki, Tanja Ruokoranta, Pauliina Rumm, Dean Anthony Lee, Esa Pitkänen, Tomi P Mäkelä, Kimmo Porkka, Oscar E. Brück, Olli Dufva, Satu Mustjoki

Blood (2024) 144 (Supplement 1): 329.

https://doi.org/10.1182/blood-2024-199448

Published: 2024

Journal Articles

Clonal Hematopoiesis Mutations and Cell-Free DNA Characteristics in Patients with High-Risk Large B-Cell Lymphomas

Miro Nylén, Leo Meriranta, Emil Hiitola, Maare Arffman, Harald Holte, Judit Mészáros Joergensen, Peter Brown, Sirkku Jyrkkiö, Mats Jerkeman, Øystein Fluge, Magnus Björkholm, Lars Møller Pedersen, Mikael Eriksson, Satu Mustjoki, Sirpa Leppä, Mikko Myllymäki

Blood (2024) 144 (Supplement 1): 1601.

https://doi.org/10.1182/blood-2024-201928

Published: 2024

Journal Articles

Comprehensive Drug Profiling and CRISPR Screening Reveal Essential Pathways for NK Cell Cytotoxicity

Blood (2024) 144 (Supplement 1): 913.

https://doi.org/10.1182/blood-2024-202448

Published: 2024

Journal Articles

Comparison of Anti-PD1, Anti-CTLA4 and Anti-TIM3 in Treatment of AML Patients with Single-Cell Transcriptomics Displays Different Effects on Immune Subtypes

Sofia Forstén, Livius Penter, Oscar E. Brück, Johannes Smolander, Karita Peltonen, Harri Lähdesmäki, Mika Kontro, Kimmo Porkka, Hussein A. Abbas, Catherine J. Wu, Jani Huuhtanen, Satu Mustjoki

Blood (2024) 144 (Supplement 1): 1529.

https://doi.org/10.1182/blood-2024-199471

Published: 2024

Journal Articles

Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responses

Blood (2024) 144 (15): 1595–1610.

https://doi.org/10.1182/blood.2023022884

Published: 2024

Includes: Supplemental data

Journal Articles

Natural Killer Cells Are Active Against Myeloma, Leukemia or Lymphoma Cells with Loss of Tumor Suppressor Genes

Olga Dashevsky, Sara Gandolfi, Olli Dufva, Ricardo De Matos Simoes, Jani Huuhtanen, Benjamin G. Barwick, Ryosuke Shirasaki, Michal Sheffer, Aidan Culhane, Jonathan D. Licht, Christine-Ivy Liacos, Evangelos Terpos, Efstathios Kastritis, Meletios Athanasios Dimopoulos, Lawrence H. Boise, Francisca Vazquez, Matti Kankainen, Satu Mustjoki, Constantine S Mitsiades

Blood (2023) 142 (Supplement 1): 6842.

https://doi.org/10.1182/blood-2023-189570

Published: 2023

Journal Articles

Clonal Hematopoiesis Associated with Rheumatoid Arthritis

Blood (2023) 142 (Supplement 1): 2698.

https://doi.org/10.1182/blood-2023-173664

Published: 2023

Journal Articles

Molecular Attributes of CAR T Cell Fitness in Patients with Chronic Lymphocytic Leukemia

Xiaoli Mi, Dennis Yuan, Rebecca Murray, Jani Huuhtanen, Beatrice Zhang, Jean Quentin, Olga Shestova, David L. Porter, Satu Mustjoki, Saar Gill, Dan A. Landau

Blood (2023) 142 (Supplement 1): 3452.

https://doi.org/10.1182/blood-2023-187956

Published: 2023

Journal Articles

High-Throughput Screens Identify NEDD8 Inhibition As a Strategy to Augment Natural Killer Cell Cytotoxicity Against Blood Cancers

Jonas Bouhlal, Petra Nygren, Emmi Jokinen, Essi Laajala, Aleksandr Ianevski, Diogo Dias, Jay Klievink, Hanna Lähteenmäki, Hanna Duàn, Khalid Saeed, Dean Anthony Lee, Tero Aittokallio, Olli Dufva, Satu Mustjoki

Blood (2023) 142 (Supplement 1): 3634.

https://doi.org/10.1182/blood-2023-174386

Published: 2023

Journal Articles

Primary Acute Myeloid Leukemia Cells Trigger Distinct Activation Patterns in Expanded NK Cells

Hanna Duàn, Olli Dufva, Emmi Jokinen, Hanna Lähteenmäki, Jay Klievink, Jonas Bouhlal, Jason Theodoropoulos, Heikki Kuusanmäki, Tanja Ruokoranta, Pauliina Rumm, Dean Anthony Lee, Esa Pitkänen, Tomi P Mäkelä, Kimmo Porkka, Oscar Brück, Satu Mustjoki

Blood (2023) 142 (Supplement 1): 66.

https://doi.org/10.1182/blood-2023-174037

Published: 2023

Journal Articles

Single-Cell Transcriptomics Reveals Adaptive NK Cell and Antigen-Specific T Cell Responses Shaped by CMV Viremia Post-Hematopoietic Stem Cell Transplant

Aino-Elina Häkkinen, Jani Huuhtanen, Sofie Lundgren, Riitta Niittyvuopio, Harri Lähdesmäki, Mikko A. I. Keränen, Mikko Myllymäki, Satu Mustjoki

Blood (2023) 142 (Supplement 1): 4786.

https://doi.org/10.1182/blood-2023-179714

Published: 2023

Journal Articles

Single-Cell Analysis of Immune Recognition in Chronic Myeloid Leukemia Patients Following Tyrosine Kinase Inhibitor Discontinuation

Blood (2023) 142 (Supplement 1): 3146.

https://doi.org/10.1182/blood-2023-185630

Published: 2023

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Anti-TIM3 with hypomethylating agent revives NK and cytotoxic CD4+ T cell activity in patients with AML or MDS

Modeling of a hyper-inflammatory hematopoietic niche ex vivo reveals a multi-step process driving CAR T- cell associated myeloid leukemia in multiple myeloma

A randomized study of ropeginterferon in combination with bosutinib in newly diagnosed chronic myeloid leukemia (CML) patients in chronic Phase. the bosupeg trial from the Nordic CML study group

Tracing the evolution of clonal T cell responses in LGL leukemia with single-cell whole genome sequencing

High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia

Predicting Antigen-Specific T Cell Immunity Against Wilms Tumor 1 in Hematologic Cancer

Bone Marrow Stromal Cells Hamper Leukemia Cell Induced NK Cell Activation and Cytotoxicity

Computational Cytomorphological Analyses Identifies Bone Marrow Erythroblast Proportion As a Biomarker of Treatment-Free Remission in CML

Genomic Subtypes of AML Define Sensitivity to NK Cell Cytotoxicity

Clonal Hematopoiesis Mutations and Cell-Free DNA Characteristics in Patients with High-Risk Large B-Cell Lymphomas

Comprehensive Drug Profiling and CRISPR Screening Reveal Essential Pathways for NK Cell Cytotoxicity

Comparison of Anti-PD1, Anti-CTLA4 and Anti-TIM3 in Treatment of AML Patients with Single-Cell Transcriptomics Displays Different Effects on Immune Subtypes

Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responses

Natural Killer Cells Are Active Against Myeloma, Leukemia or Lymphoma Cells with Loss of Tumor Suppressor Genes

Clonal Hematopoiesis Associated with Rheumatoid Arthritis

Molecular Attributes of CAR T Cell Fitness in Patients with Chronic Lymphocytic Leukemia

High-Throughput Screens Identify NEDD8 Inhibition As a Strategy to Augment Natural Killer Cell Cytotoxicity Against Blood Cancers

Primary Acute Myeloid Leukemia Cells Trigger Distinct Activation Patterns in Expanded NK Cells

Single-Cell Transcriptomics Reveals Adaptive NK Cell and Antigen-Specific T Cell Responses Shaped by CMV Viremia Post-Hematopoietic Stem Cell Transplant

Single-Cell Analysis of Immune Recognition in Chronic Myeloid Leukemia Patients Following Tyrosine Kinase Inhibitor Discontinuation

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American Society of Hematology

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