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Tiina Kelkka
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Journal Articles

Clonal Hematopoiesis Associated with Rheumatoid Arthritis

Emil Hiitola, Juuso Korhonen, Jukka Koskela, Matti Kankainen, Milla Alakuijala, Heidi Kokkonen, Aoxing Liu, Paavo Häppölä, Paula Savola, Tiina Kelkka, Marjatta Leirisalo-Repo, Ritva Peltomaa, Laura Pirilä, Pia Isomäki, Markku Kauppi, Oili Kaipiainen-Seppänen, FinnGen Consortium, Giulio Genovese, Andrea Ganna, Solbritt Rantapää-Dahlqvist, Satu Mustjoki, Mikko Myllymäki
Journal: Blood
Blood (2023) 142 (Supplement 1): 2698.
https://doi.org/10.1182/blood-2023-173664
Published: 2023
Journal Articles

Clonal Trafficking of Individual T Cells between Peripheral Blood and Inflamed Synovial Tissue in Patients with Immune-Mediated Refractory Arthritis

Dipabarna Bhattacharya, Jason Theodoropoulos, Katariina Nurmi, Timo Juutilainen, Kari K Eklund, Riitta Koivuniemi, Tiina Kelkka, Satu Mustjoki, Tapio Lönnberg
Journal: Blood
Blood (2023) 142 (Supplement 1): 1178.
https://doi.org/10.1182/blood-2023-181206
Published: 2023
Journal Articles

Somatic Mutations in T Cells in Patients with Hematological Diseases

Sofie Lundgren, Timo Järvinen, Mikko A Keränen, Jason Theodoropoulos, Daehong Kim, Urpu Salmenniemi, Gunilla Walldin, Paula Savola, Tiina Kelkka, Hanna Rajala, Pekka Ellonen, Eva Hellström-Lindberg, Maija Itälä-Remes, Mikko Myllymäki, Matti Kankainen, Satu Mustjoki
Journal: Blood
Blood (2022) 140 (Supplement 1): 5496–5497.
https://doi.org/10.1182/blood-2022-163112
Published: 2022
Journal Articles

Synergistic Role of Leukemic and Non-Leukemic Immune Repertoires in CD8+ T-Cell Large Granular Lymphocytic Leukemia As Identified By Single-Cell Transcriptomics

Dipabarna Bhattacharya, Jani Huuhtanen, Matti Kankainen, Tapio Lönnberg, Cassandra M Kerr, Jason Theodoropoulos, Hanna Rajala, Tiina Kasanen, Till Braun, Antonella Teramo, Renato Zambello, Marco Herling, Fumihiro Ishida, Toru Kawakami, Marko Salmi, Thomas P. Loughran, Jr., Jaroslaw P. Maciejewski, Harri Lähdesmäki, Tiina Kelkka, Satu Mustjoki
Journal: Blood
Blood (2021) 138 (Supplement 1): 1318.
https://doi.org/10.1182/blood-2021-146539
Published: 2021
Journal Articles

T Cell Landscape of Immune Aplastic Anemia Reveals a Convergent Antigen-Specific Signature

Jani Huuhtanen, BMed, Sofie Lundgren, BMed, Mikko A Keränen, MD PhD, Xingmin Feng, PhD, Cassandra M Kerr, MS, Emmi Jokinen, MSc, Markus Heinonen, PhD, Paula Savola, MD PhD, Tiina Kelkka, PhD, Freja Ebeling, MD PhD, Georgina L Ryland, Lucy Fox, Piers Blombery, MBBS, Eva Hellstrom Lindberg, MD PhD, Neal S. Young, MD, Jaroslaw P. Maciejewski, MD PhD, Harri Lähdesmäki, PhD, Satu Mustjoki, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 108.
https://doi.org/10.1182/blood-2019-127790
Published: 2019
Journal Articles

Somatic Mutations in T Cells As Possible Regulators of Immunodeficiency

Paula Savola, MD, Timi Martelius, MD PhD, Matti Kankainen, PhD, Yrjö Koski, BTech, Samuli Eldfors, PhD, Jani Huuhtanen, BMed, Tiina Kelkka, PhD, Sofie Lundgren, BMed, Pekka Ellonen, BSc, Panu Kovanen, MD PhD, Soili Kytölä, PhD, Mikko Seppänen, MD PhD, Satu Mustjoki, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 515.
https://doi.org/10.1182/blood-2018-99-110757
Published: 2018
Journal Articles

Next-Generation Sequencing Reveals a T Cell Receptor Signature Characteristic of Patients with Aplastic Anemia

Sofie Lundgren, BMed, Jani Huuhtanen, BMed, Mikko A Keränen, MD PhD, Cassandra M. Hirsch, Emmi Jokinen, MSc, Markus Heinonen, PhD, Paula Savola, MD, Tiina Kelkka, PhD, Freja Ebeling, MD PhD, Jaroslaw P. Maciejewski, Eva Hellström-Lindberg, MD PhD, Harri Lähdesmäki, PhD, Satu Mustjoki, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 537.
https://doi.org/10.1182/blood-2018-99-117811
Published: 2018
Journal Articles

Somatic Mutations in CD8+ T Cells in Patients with Chronic Immune Thrombocytopenia Are Associated with Increased Clonality and Cytotoxic Phenotype of CD8+ T Cells

Hanna Rajala, MD PhD, Paula Savola, MD, Sofie Lundgren, BMed, Samuli Eldfors, PhD, Tiina Kelkka, PhD, Freja Ebeling, MD PhD, Satu Mustjoki, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 131.
https://doi.org/10.1182/blood-2018-99-113373
Published: 2018
Journal Articles

Mutational Landscape of Aggressive Natural Killer Cell Leukemia and Drug Sensitivity Profiling Reveal Therapeutic Options in Natural Killer Cell Malignancies

Olli Dufva, Matti Kankainen, PhD, Tiina Kelkka, PhD, Shady Adnan Awad, MD, Nodoka Sekiguchi, MD, Bhagwan Yadav, MSc, Samuli Eldfors, MSc, Heikki Kuusanmäki, MSc, Emma I Andersson, MSc, Disha Malani, MSc, Paavo Pietarinen, MSc, Leena Saikko, Panu E Kovanen, MD PhD, Junji Suzumiya, MD PhD, Ritsuro Suzuki, MD PhD, Young Hyeh Ko, MD, Won Seog Kim, MD PhD, Shih-Sung Chuang, MD, Thomas P. Loughran, Jr., MD, Wing Chung Chan, MD, Koichi Ohshima, MD PhD, Tero Aittokallio, Fumihiro Ishida, MD PhD, Satu Mustjoki, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2921.
https://doi.org/10.1182/blood.V128.22.2921.2921
Published: 2016
Journal Articles

Exome Sequencing of Aggressive Natural Killer Cell Leukemia and Drug Profiling Highlight Candidate Driver Pathways in Malignant Natural Killer Cells

Olli Dufva, BMed, Tiina Kelkka, PhD, Shady Awad, MD, Nodoka Sekiguchi, MD, Heikki Kuusanmäki, MSc, Emma I Andersson, MSc, Samuli Eldfors, MSc, Disha Malani, MSc, Paavo Pietarinen, MSc, Leena Saikko, Panu E Kovanen, MD PhD, Junji Suzumiya, MD PhD, Koichi Ohshima, MD PhD, Young Hyeh Ko, MD, Won Seog Kim, MD PhD, Shih-Sung Chuang, MD, Thomas P. Loughran, Jr., MD, Wing C Chan, MD, Fumihiro Ishida, MD PhD, Satu Mustjoki, MD PhD
Journal: Blood
Blood (2015) 126 (23): 700.
https://doi.org/10.1182/blood.V126.23.700.700
Published: 2015