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Laurent Genestier
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Journal Articles

Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responses

Jana von Jan, Sanna Timonen, Till Braun, Qu Jiang, Aleksandr Ianevski, Yayi Peng, Kathleen McConnell, Paola Sindaco, Tony Andreas Müller, Sabine Pützer, Hanna Klepzig, Dennis Jungherz, Annika Dechow, Linus Wahnschaffe, Anil K. Giri, Matti Kankainen, Heikki Kuusanmäki, Heidi A. Neubauer, Richard Moriggl, Paolo Mazzeo, Nicole Schmidt, Raphael Koch, Michael Hallek, Amel Chebel, David Armisen, Laurent Genestier, Emmanuel Bachy, Anjali Mishra, Alexandra Schrader, Tero Aittokallio, Satu Mustjoki, Marco Herling
Journal: Blood
Blood (2024) 144 (15): 1595–1610.
https://doi.org/10.1182/blood.2023022884
Published: 2024
Includes: Supplemental data
Journal Articles

BTG1 inactivation drives lymphomagenesis and promotes lymphoma dissemination through activation of BCAR1

Lorric Delage, Mireille Lambert, Émilie Bardel, Cindy Kundlacz, Dimitri Chartoire, Axel Conchon, Anne-Laure Peugnet, Lucas Gorka, Patrick Auberger, Arnaud Jacquel, Carole Soussain, Olivier Destaing, Henri-Jacques Delecluse, Susanne Delecluse, Samir Merabet, Alexandra Traverse-Glehen, Gilles Salles, Emmanuel Bachy, Marc Billaud, Hervé Ghesquières, Laurent Genestier, Jean-Pierre Rouault, Pierre Sujobert
Journal: Blood
Blood (2023) 141 (10): 1209–1220.
https://doi.org/10.1182/blood.2022016943
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

KIR3DL2 contributes to the typing of acute adult T-cell leukemia and is a potential therapeutic target

Morgane Cheminant, Ludovic Lhermitte, Julie Bruneau, Hélène Sicard, Cécile Bonnafous, Aurore Touzart, Estelle Bourbon, Nicolas Ortonne, Laurent Genestier, Philippe Gaulard, Patricia Palmic, Felipe Suarez, Laurent Frenzel, Louise Naveau, Ali Bazarbachi, Mickaël Dussiot, Laetitia Waast, Véronique Avettand-Fenoel, Chantal Brouzes, Claudine Pique, Yves Lepelletier, Vahid Asnafi, Ambroise Marçais, Olivier Hermine
Journal: Blood
Blood (2022) 140 (13): 1522–1532.
https://doi.org/10.1182/blood.2022016765
Published: 2022
Includes: Supplemental data
Journal Articles

Chromatin Accessibility Profiling to Increase Diagnostic Accuracy and Refine Cell-of-Origin Classification of Mature T-Cell Lymphomas

Edith Julia, Sylvain Mareschal, Amel Chebel, Camille Golfier, Tony Andreas Müller, Camille Lours, Sofiane Hadj-Hamou, Nathalie Bissay, Manon Tschanz, Michele Ceribelli, Dimitri Chartoire, Aurélie Vernay, Sylvain Carras, David Sibon, Ambroise Marçais, Camille Laurent, Laurent Martin, Vahid Asnafi, Lea Payen, Damien Sanlaville, Claire Bardel-Danjean, Mikael Roussel, Vanessa Szablewski, Fanny Drieux, Philippe Ruminy, Marco Herling, Catherine Chassagne-Clément, Gilles Salles, Pierre Sujobert, Alexandra Traverse-Glehen, Lucile Baseggio, Laurence De Leval, Louis M. Staudt, Philippe Gaulard, Laurent Genestier, Emmanuel Bachy
Journal: Blood
Blood (2021) 138 (Supplement 1): 809.
https://doi.org/10.1182/blood-2021-150034
Published: 2021
Journal Articles

Chronic Borrelia burgdorferi infection triggers NKT lymphomagenesis

Rémy Robinot, Emmanuel Bachy, Sammara Chaubard, Mirjam Urb, Sylvain Carras, Emilie Bardel, Dimitri Chartoire, Alexandra Traverse-Glehen, Patrice N. Marche, Gilles Salles, Benoit Jaulhac, Laurent Genestier
Journal: Blood
Blood (2018) 132 (25): 2691–2695.
https://doi.org/10.1182/blood-2018-07-863381
Published: 2018
Includes: Supplemental data
Journal Articles

Identification of Previously Unrecognized CD1d-Restricted Peripheral T Cell Lymphomas (PTCLs) in Mouse and Human Reveals Blocking Anti-CD1d Monoclonal Antibodies As a New Therapeutic Possibility in PTCLs

Emmanuel Bachy, MDPhD, Mirjam Urb, PhD, Gabriel Bricard, PhD, Shilpi Jayaswal, PhD, Remy Robinot, Alexandra Traverse-Glehen, MD PhD, Sophie Gazzo, PhD, Lucile Baseggio, PharmD PhD, Martine Ffrench, MD PhD, Paul Mondiere, Morgan Taillardet, PhD, Gilles Salles, MDPhD, Joel Lachuer, PhD, Olivier Hermine, MD PhD, Vahid Asnafi, MDPhD, Mikael Roussel, MD PhD, Thierry Lamy, Patrice Marche, PhD, Philippe Gaulard, MD, Mitchell Kronenberg, PhD, Thierry Defrance, PhD, Laurent Genestier, PhD
Journal: Blood
Blood (2014) 124 (21): 4485.
https://doi.org/10.1182/blood.V124.21.4485.4485
Published: 2014
Journal Articles

P53 Prevents TCR-Dependent Peripheral T-Cell Lymphomagenesis From Chronically Stimulated T Cells.

Emmanuel Bachy, MD, Alexandra Traverse-Glehen, Sophie Gazzo, PhD, Baseggio Lucile, Pharm, PhD, Martine Ffrench, MD, PhD, Morgan Taillardet, PhD, Gilles Salles, MD, Thierry Defrance, PhD, Laurent Genestier, PhD
Journal: Blood
Blood (2012) 120 (21): 2401.
https://doi.org/10.1182/blood.V120.21.2401.2401
Published: 2012
Journal Articles

The thymus-independent immunity conferred by a pneumococcal polysaccharide is mediated by long-lived plasma cells

Morgan Taillardet, Ghina Haffar, Paul Mondière, Marie-Jeanne Asensio, Hanane Gheit, Nicolas Burdin, Thierry Defrance, Laurent Genestier
Journal: Blood
Blood (2009) 114 (20): 4432–4440.
https://doi.org/10.1182/blood-2009-01-200014
Published: 2009
Includes: Supplemental data
Journal Articles

Cathepsin-B-dependent apoptosis triggered by antithymocyte globulins: a novel mechanism of T-cell depletion

Marie-Cécile Michallet, Frederic Saltel, Xavier Preville, Monique Flacher, Jean-Pierre Revillard, Laurent Genestier
Journal: Blood
Blood (2003) 102 (10): 3719–3726.
https://doi.org/10.1182/blood-2003-04-1075
Published: 2003
Journal Articles

Induction of Fas (Apo-1, CD95)-Mediated Apoptosis of Activated Lymphocytes by Polyclonal Antithymocyte Globulins

Laurent Genestier, Sylvie Fournel, Monique Flacher, Olga Assossou, Jean-Pierre Revillard, Nathalie Bonnefoy-Berard
Journal: Blood
Blood (1998) 91 (7): 2360–2368.
https://doi.org/10.1182/blood.V91.7.2360
Published: 1998
Journal Articles

Fas-Independent Apoptosis of Activated T Cells Induced by Antibodies to the HLA Class I α1 Domain

Laurent Genestier, Romain Paillot, Nathalie Bonnefoy-Berard, Geneviéve Meffre, Monique Flacher, David Fèvre, Yong Jun Liu, Philippe Le Bouteiller, Herman Waldmann, Victor H. Engelhard, Jacques Banchereau, Jean Pierre Revillard
Journal: Blood
Blood (1997) 90 (9): 3629–3639.
https://doi.org/10.1182/blood.V90.9.3629
Published: 1997
Journal Articles

Antibodies to HLA Class I α1 Domain Trigger Apoptosis of CD40-Activated Human B Lymphocytes

Laurent Genestier, Geneviève Meffre, Pierre Garrone, Jean-Jacques Pin, Yong-Jun Liu, Jacques Banchereau, Jean-Pierre Revillard
Journal: Blood
Blood (1997) 90 (2): 726–735.
https://doi.org/10.1182/blood.V90.2.726
Published: 1997