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Journal Articles

Valemetostat Monotherapy in Patients with Relapsed or Refractory Large B-Cell Lymphoma: Primary Results of the Phase 2 Valym Study from the Lysa

Emmanuel Bachy, Bernard Drenou, Fabrice Jardin, Keiko Nakajima, Katell Le Du, Gandhi Damaj, Fontanet Bijou, Borhane Slama, Gian Matteo Pica, Gaetan Vanstraelen, Charles Herbaux, Roch Houot, Francois Lemonnier, Julie Gay, Pierre Sujobert, Marguerite Fournier, Marlene Ochmann, Romain Guieze, Jorge Zeron, Alexandra Traverse-Glehen, Jean Marc Schiano De Colella, Franck Morschhauser
Journal: Blood
Blood (2024) 144 (Supplement 1): 4479.
https://doi.org/10.1182/blood-2024-193960
Published: 2024
Journal Articles

Deciphering Thrombosis Risk in Vexas Syndrome Patients through Thrombin Generation Assay Andthromboelastography

Mael Heiblig, Christophe Nougier, Jamilloux Yvan, Pierre Sujobert, Yesim Dargaud
Journal: Blood
Blood (2023) 142 (Supplement 1): 1280.
https://doi.org/10.1182/blood-2023-185809
Published: 2023
Journal Articles

Genotype-Phenotype Mapping Via Single-Cell Multi-Omics Identifies Therapeutic Vulnerabilities in Vexas Syndrome

Saravanan Ganesan, Rebecca Murray, Jesus Sotelo, Theo Botella, Elliot Eton, Nada Chraiki, Carolyne Croizier, Franco Izzo, Catherine Potenski, Benjamin Terrier, Mael Heiblig, Pierre Sujobert, Olivier Kosmider, David B Beck, Dan A. Landau
Journal: Blood
Blood (2023) 142 (Supplement 1): 813.
https://doi.org/10.1182/blood-2023-184313
Published: 2023
Journal Articles

Deep Learning Based Blood Abnormalities Detection As a Tool for Vexas Syndrome Screening

Cedric De Almeida Braga, Maxence Bauvais, Pierre Sujobert, Mael Heiblig, Maxime Jullien, Baptiste Le Calvez, Camille Richard, Valentin Le Roc'h, Emmanuelle Rault, Olivier Herault, Pierre Peterlin, Alice Garnier, Patrice Chevallier, Simon Bouzy, Yannick LE Bris, Antoine Neel, Julie Graveleau, Perrine Paul-Gilloteaux, Olivier Kosmider, Nicolas Normand, Marion Eveillard
Journal: Blood
Blood (2023) 142 (Supplement 1): 3648.
https://doi.org/10.1182/blood-2023-186874
Published: 2023
Journal Articles

BTG1 inactivation drives lymphomagenesis and promotes lymphoma dissemination through activation of BCAR1

Lorric Delage, Mireille Lambert, Émilie Bardel, Cindy Kundlacz, Dimitri Chartoire, Axel Conchon, Anne-Laure Peugnet, Lucas Gorka, Patrick Auberger, Arnaud Jacquel, Carole Soussain, Olivier Destaing, Henri-Jacques Delecluse, Susanne Delecluse, Samir Merabet, Alexandra Traverse-Glehen, Gilles Salles, Emmanuel Bachy, Marc Billaud, Hervé Ghesquières, Laurent Genestier, Jean-Pierre Rouault, Pierre Sujobert
Journal: Blood
Blood (2023) 141 (10): 1209–1220.
https://doi.org/10.1182/blood.2022016943
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

Correlation of Clonal Hematopoiesis in Vexas Syndrome with Immunophenotype Alterations in CD34+ HSPCs (Hematopoietic Stem Progenitors Cells): Multiparametric Flow Cytometry Heterogeneity in CD34+CD38- Stem Cells Fraction and Upregulation of CD90 Thy-1 By Unsupervised Strategy Using PCA, Tsnee and Flowsom

Adriana Plesa, Joris Gutrin, Christophe Roumier, Sandrine Hayette, Isabelle Tigaud, Sarah Huet, Delphine Manzoni, Florent Dumezy, Fiorenza Barraco, Herve Ghesquieres, Claude Preudhomme, Pierre Sujobert, Mael Heiblig
Journal: Blood
Blood (2022) 140 (Supplement 1): 4086–4087.
https://doi.org/10.1182/blood-2022-169959
Published: 2022
Journal Articles

Thrombosis with Non-Proliferative Complete Blood Count Indicative of Underlying Myeloproliferative Neoplasm, Sythrom, a Study on Behalf of the FIM Group

Yannick LE Bris, Jean Galtier, Dina Naguib, Mathieu Wemeau, Jean Claude Chomel, Laurence Legros, Yan Beauverd, Lise Willems, Guillaume Denis, Françoise Boyer perrard, Damien Luque-Paz, Kamel Laribi, Mélanie Mercier, Pascale Cony-Makhoul, Olivier Herault, Lydia Roy, Pierre Sujobert, Lenaig Le Clech, Sylvie Tondeur, Gaelle Laboure, Jerome Rey, Guillou Sophie, Cedric Pastoret, Pascaline Etancelin, Suzanne Tavitian, Charles Bescond, Francois Girodon, Shanti Amé, Viviane Dubruille, Eric Lippert, Chloe James, Barbara Burroni, Marc Fouassier, Marie C Béné, Jean Christophe Ianotto
Journal: Blood
Blood (2022) 140 (Supplement 1): 9668–9669.
https://doi.org/10.1182/blood-2022-159928
Published: 2022
Journal Articles

Ruxolitinib is more effective than other JAK inhibitors to treat VEXAS syndrome: a retrospective multicenter study

Clinical Trials & Observations
Maël Heiblig, Marcela A. Ferrada, Matthew T. Koster, Thomas Barba, Mathieu Gerfaud-Valentin, Arsène Mékinian, Henrique Coelho, Gaelle Fossard, Fiorenza Barraco, Lionel Galicier, Boris Bienvenu, Pierre Hirsch, Guillaume Vial, Anne Blandine Boutin, Joris Galland, Guillaume Le Guenno, Adrien Bigot, Kenneth J. Warrington, Tanaz A. Kermani, Peter C. Grayson, Bhavisha A. Patel, David B. Beck, Yvan Jamilloux, Pierre Fenaux, Pierre Sujobert
Journal: Blood
Blood (2022) 140 (8): 927–931.
https://doi.org/10.1182/blood.2022016642
Published: 2022
Includes: Supplemental data
Journal Articles

Clinical Efficacy of JAK Inhibitors in Patients with Vexas Syndrome: A Multicenter Retrospective Study

Maël Heiblig, Marcela A Ferrada, Mathieu Gerfaud-Valentin, Thomas Barba, Arsène Mékinian, Matthew Koster, Henrique Coelho, Gaelle Fossard, Fiorenza Barraco, Lionel Galicier, Boris Bienvenu, Pierre Hirsch, Guillaume Vial, Anne Blandine Boutin, Guillaume Le guenno, Adrien Bigot, Kenneth Warrington, Tanaz Kermani, Yvan Jamilloux, Peter C Grayson, Bhavisha A. Patel, David B. Beck, Pierre Fenaux, Pierre Sujobert
Journal: Blood
Blood (2021) 138 (Supplement 1): 2608.
https://doi.org/10.1182/blood-2021-150394
Published: 2021
Journal Articles

Chromatin Accessibility Profiling to Increase Diagnostic Accuracy and Refine Cell-of-Origin Classification of Mature T-Cell Lymphomas

Edith Julia, Sylvain Mareschal, Amel Chebel, Camille Golfier, Tony Andreas Müller, Camille Lours, Sofiane Hadj-Hamou, Nathalie Bissay, Manon Tschanz, Michele Ceribelli, Dimitri Chartoire, Aurélie Vernay, Sylvain Carras, David Sibon, Ambroise Marçais, Camille Laurent, Laurent Martin, Vahid Asnafi, Lea Payen, Damien Sanlaville, Claire Bardel-Danjean, Mikael Roussel, Vanessa Szablewski, Fanny Drieux, Philippe Ruminy, Marco Herling, Catherine Chassagne-Clément, Gilles Salles, Pierre Sujobert, Alexandra Traverse-Glehen, Lucile Baseggio, Laurence De Leval, Louis M. Staudt, Philippe Gaulard, Laurent Genestier, Emmanuel Bachy
Journal: Blood
Blood (2021) 138 (Supplement 1): 809.
https://doi.org/10.1182/blood-2021-150034
Published: 2021
Journal Articles

Therapeutic options in VEXAS syndrome: insights from a retrospective series

Clinical Trials & Observations
Estelle Bourbon, Maël Heiblig, Mathieu Gerfaud Valentin, Thomas Barba, Cécile-Audrey Durel, Jean Christophe Lega, Fiorenza Barraco, Pascal Sève, Yvan Jamilloux, Pierre Sujobert
Journal: Blood
Blood (2021) 137 (26): 3682–3684.
https://doi.org/10.1182/blood.2020010177
Published: 2021
Includes: Supplemental data
Journal Articles

A personalized approach to guide allogeneic stem cell transplantation in younger adults with acute myeloid leukemia

Clinical Trials & Observations
Laurène Fenwarth, Xavier Thomas, Stéphane de Botton, Nicolas Duployez, Jean-Henri Bourhis, Auriane Lesieur, Gael Fortin, Paul-Arthur Meslin, Ibrahim Yakoub-Agha, Pierre Sujobert, Pierre-Yves Dumas, Christian Récher, Delphine Lebon, Céline Berthon, Mauricette Michallet, Arnaud Pigneux, Stéphanie Nguyen, Sylvain Chantepie, Norbert Vey, Emmanuel Raffoux, Karine Celli-Lebras, Claude Gardin, Juliette Lambert, Jean-Valère Malfuson, Denis Caillot, Sébastien Maury, Benoît Ducourneau, Pascal Turlure, Emilie Lemasle, Cécile Pautas, Sylvie Chevret, Christine Terré, Nicolas Boissel, Gérard Socié, Hervé Dombret, Claude Preudhomme, Raphael Itzykson
Journal: Blood
Blood (2021) 137 (4): 524–532.
https://doi.org/10.1182/blood.2020005524
Published: 2021
Includes: Supplemental data
Journal Articles

Real Time Pathological and Molecular Characterization of Aggressive B-Cell Lymphomas Based on a National Network. a Lysa Project

Christiane Copie Bergman, MDPhD, Elodie Bohers, PhD, Peggy Dartigues-Cuillères, MD, Pierre-Julien Viailly, Philippe Ruminy, PhD, Vinciane Marchand, Marie-Helene Delfau-Larue, Corinne Haioun, MDPhD, Cyrielle Robe, Elsa Poullot, MD, Steven Le Gouill, MD PhD, Yannick Le Bris, PharmD, Céline Bossard, MD, Anne Moreau, MD, Vincent Ribrag, MD, Valérie Camara-clayette, PhD, Cyril Quivoron, PhD, Gilles Salles, MDPhD, Sophie Cotteret, MD PhD, Pierre Sujobert, MD PhD, Alexandra Traverse-Glehen, MD PhD, Claire Mauduit, Pascaline Etancelin, Sarah Huet, Liana Veresezan, MD, Krimo Bouabdallah, MD, Marie Parrens, MD, Audrey Gros, PhD, Samuel Amintas, David Sibon, MD PhD, Ludovic Lhermitte, MD PhD, Thomas Steimle, Sophie Kaltenbach, Bettina Fabiani, MD, Camille Laurent, MD PhD, Barbara Burroni, Laurent Martin, MD PhD, Thierry Jo Molina, MDPhD, Lysa LYSARC study group, Fabrice Jardin, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-141953
Published: 2020
Journal Articles

Impact of DNMT3a Status on Post Induction NPM1 MRD Predictive Value on Survival in Elderly AML Patients Treated Intensively

Maël Heiblig, MD, Hélène Labussière, MD, Marie Virginie Larcher, MD, Gaelle Fossard, MD, Marie Balsat, MD, Sophie Ducastelle, MD, Sandrine Loron, MD, Sandrine Hayette, PhD, Sarah Huet, Pierre Sujobert, MD PhD, Fiorenza Barraco, MD, Xavier Thomas, MD PhD, Alice Marceau, Delphine Lebon, MD, Laure Goursaud, Isabelle Plantier, MD, Laure Stalnikiewich, Cecile Frimat, Nathalie Cambier, Nicolas Duployez, PharmD, PhD, Herve Ghesquieres, MD PhD, Claude Preudhomme, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-141890
Published: 2020
Journal Articles

The Broad Spectrum of TP53 Variants in CLL: NGS Analysis of 573 Pathogenic TP53 Variants

Gregory Lazarian, PharmD, Floriane Theves, Myriam Hormi, Virginie Eclache, Stéphanie Poulain, MD, Audrey Bidet, Cedric Pastoret, MD, Lauren Veronese, MD PhD, Eric Delabesse, MD PhD, Marie-Hélène Estienne, Nathalie Nadal, Frederic Davi, MD PhD, Florence Nguyen-Khac, MD PhD, Laurence Lode, Pierre Sujobert, MD PhD, Dina Naguib, MD, Sophie Raynaud, Stephane Giraudier, MD PhD, Olivier Kosmider, PharmD, PhD, Pascaline Etancelin, Pascale Cornillet-Lefebvre, Laurent Miguet, DPhil, Veronique Leblond, MD PhD, Remi Letestu, Thierry Soussi, Florence Cymbalista, MD PhD, Fanny Baran-Marszak, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3021.
https://doi.org/10.1182/blood-2019-130907
Published: 2019
Journal Articles

PKR-like Endoplasmic Reticulum Kinase Mediates Apoptosis Induced By Pharmacological AMP-Activated Protein Kinase Activation in Acute Myeloid Leukemia

Laury Poulain, PhD, Adrien Grenier, MD PhD, Johanna Mondesir, MD, Arnaud Jacquel, PhD, Claudie Bosc, Lucille Stuani, PhD, Rudy Birsen, MD, Sarah Mouche, Justine Decroocq, MD, Fetta Mazed, PhD, Benoit Viollet, PhD, Patrick Auberger, PhD, Pierre Sujobert, MD PhD, Didier Bouscary, MD PhD, Jean-Emmanuel Sarry, PhD, Jerome Tamburini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2552.
https://doi.org/10.1182/blood-2019-123364
Published: 2019
Journal Articles

Integrating ELN Criteria and a 'Knowledge Bank' Approach to Guide Allogeneic Stem Cell Transplantation (SCT) Indication in Younger Adults with Acute Myeloid Leukemia (AML): An Acute Leukemia French Association Study

Laurène Fenwarth, MD MSc, Raphael Itzykson, MD PhD, Stephane De Botton, MD PhD, Nicolas Duployez, PharmD, PhD, Pierre Sujobert, MD PhD, Céline Berthon, MD PhD, Arnaud Pigneux, Sylvain Chantepie, MD, Christian Recher, MD PhD, Emmanuel Raffoux, MD, Juliette Lambert, MD, Karine Celli-Lebras, CRA, Denis Caillot, MD, Benoit Ducourneau, PharmD, Pascal Turlure, MD, Emilie Lemasle, MD, Cecile Pautas, MD, Norbert Vey, MD PhD, Sylvie Chevret, MD PhD, Christine Terré, PharmD, PhD, Xavier Thomas, MD PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1423.
https://doi.org/10.1182/blood-2019-122468
Published: 2019
Journal Articles

A French Multicentric Prospective Cohort of 6000 Patients with Integrative Epidemiological, Clinical, Biological and Treatment Data to Improve Knowledge on Outcome of Lymphoma Patients: Pilot Phase Results of the Real World Data in Lymphoma and Survival in Adults (REALYSA) Study

Herve Ghesquieres, MD PhD, Cedric Rossi, MD PhD, Fanny Cherblanc, PhD, Sandra Le Guyader, PhD, Fontanet Bijou, MD, Pierre Sujobert, MD PhD, Pascale Fabbro-Peray, MD PhD, Luc Mathieu Fornecker, MD PhD, Adeline Bernier, PhD, Isabelle Baldi, MD PhD, Krimo Bouabdallah, MD, Camille Laurent, MD PhD, Lucie Oberic, MD, Nadine Morineau, MD, Gilles A. Salles, MD PhD, Loic Ysebaert, MD PhD, Alain Monnereau, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4762.
https://doi.org/10.1182/blood-2019-129204
Published: 2019
Journal Articles

Prognostic Impact of Clonal Diversity in Acute Myeloid Leukemia (AML) Treated with Intensive Chemotherapy (IC)

Marco Cerrano, MD, Marie Passet, PharmD, Loic Vasseur, MD, Pierre Hirsch, MD PhD, Xavier Thomas, MD PhD, Samuel Quentin, Justine Pasanisi, Florence Rabian, MD, Ramy Rahmé, MD, Etienne Lengline, MD, Emmanuel Raffoux, MD, Nathalie Dhedin, MD, Marie Sebert, MD, Odile Maarek, Anna Raimbault, PhD, Karine Celli-Lebras, CRA, Lionel Ades, MD PhD, Pierre Fenaux, MD PhD, Nicolas Boissel, MD PhD, Francois Delhommeau, MD PhD, Jean Soulier, MD PhD, Herve Dombret, MD PhD, Emmanuelle Clappier, PhD PharmD, Pierre Sujobert, MD PhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2700.
https://doi.org/10.1182/blood-2019-127475
Published: 2019
Journal Articles

Cannibalistic acute myeloid leukemia with ZMYND11-MBTD1 fusion

Adriana Plesa, Pierre Sujobert
Journal: Blood
Blood (2019) 133 (16): 1789.
https://doi.org/10.1182/blood-2019-01-898619
Published: 2019