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Kenneth Warrington
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Journal Articles

Unique NK-like T cell population identified in UBA1mt cells in vexas associated with IL-8 mediated activity and cytotoxic response pathways

Free
Terra Lasho, Jenna Fernandez, Pankaj Pradeep, Christy Finke, Abhishek Mangaonkar, Nickolas Steinauer, Bhavisha Patel, Neal Young, David Beck, Kenneth Warrington, Matthew J Koster, Yael Kusne, Fernanda Guitterez-Rodrigues, Mrinal Patnaik
Journal: Blood
Blood (2025) 146 (Supplement 1): 1428.
https://doi.org/10.1182/blood-2025-1428
Published: 2025
Journal Articles

Interplay between mutant DNMT3A and UBA1 worsens survival through altered inflammatory and metabolic pathways

Free
Jenna Fernandez, Jerome Hadjadj, Yael Kusne, Pankaj Pradeep, Fernanda Gutierrez-Rodrigues, Bhavisha Patel, Aubrey Pinteric, Christy Finke, Maria Sirenko, Emma Groarke, Matthew J Koster, Abhishek Mangaonkar, Naseema Gangat, Kenneth Warrington, Kaaren Reichard, Horatiu Olteanu, David Viswanatha, Rong He, Megan Sullivan, Kambiz Kalantari, Neal Young, Terra Lasho, David Beck, Mrinal Patnaik
Journal: Blood
Blood (2025) 146 (Supplement 1): 3191.
https://doi.org/10.1182/blood-2025-3191
Published: 2025
Journal Articles

Upfront therapy with allogeneic hematopoietic stem cell transplantation versus DNA methyltransferase inhibitors in patients with vexas syndrome: A comparative matched cohort efficacy analysis of 39 patients

Free
Saubia Fathima, Ali Alsugair, Kimberly Langer, Terra Lasho, Christy Finke, Mark Litzow, Aasiya Matin, Urshila Durani, Mehrdad Hefazi Torghabeh, William Hogan, Mithun Shah, Ronald Go, Gabriel Bartoo, Jade Kutzke, Kristen McCullough, Matthew J Koster, Kenneth Warrington, Kaaren Reichard, Horatiu Olteanu, Yael Kusne, Jeanne Palmer, Saurabh Chhabra, Mary Riwes, Joseph McGuirk, Elizabeth Krakow, Amelia Langston, Taxiarchis Kourelis, David Dingli, Mrinal Patnaik, Hassan Alkhateeb, Abhishek Mangaonkar
Journal: Blood
Blood (2025) 146 (Supplement 1): 981.
https://doi.org/10.1182/blood-2025-981
Published: 2025
Journal Articles

DNMT3A Mutant Clonal Hematopoiesis in Vexas Syndrome Epigenetically Potentiates IL-13 and IL-15 Inflammatory Pathways and Is Associated with Increased Mortality

Free
Jenna A. Fernandez, Yael Kusne, Fernanda Gutierrez-Rodrigues, Bhavisha A. Patel, Christy Finke, Emma M. Groarke, Matthew J Koster, Abhishek A. Mangaonkar, Naseema Gangat, Kenneth Warrington, Kaaren K. Reichard, Horatiu Olteanu, David Viswanatha, Rong He, Megan Sullivan, Kambiz Kalantari, Alexander Hines, Daniel Montes, Neal S. Young, David B Beck, Wazim Ismail Mohammed, Alexandre Gaspar-Maia, Terra L. Lasho, Mrinal M. Patnaik
Journal: Blood
Blood (2024) 144 (Supplement 1): 2686.
https://doi.org/10.1182/blood-2024-204334
Published: 2024
Journal Articles

Clonal Hematopoiesis in Vexas Syndrome

Free
Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, Yael Kusne, Jenna A. Fernandez, Terra Lasho, Ruba Shalhoub, Xiaoyang Ma, Hugh Alessi, Christy Finke, Matthew Koster, Abhishek A. Mangaonkar, Kenneth Warrington, Kebede H. Begna, Zhuoer Xie, Amanda Ombrello, David S. Viswanatha, Marcela Ferrada, Lorena Wilson, Ronald Go, Taxiarchis Kourelis, Kaaren K. Reichard, Horatiu Olteanu, Emma M. Groarke, Ivana Darden, Dalton Hironaka, Sofia Rosenzweig, Daniel L. Kastner, Katherine R. Calvo, Colin O. Wu, Peter C. Grayson, David B. Beck, Mrinal M.M. Patnaik, Neal S. Young
Journal: Blood
Blood (2022) 140 (Supplement 1): 5745–5746.
https://doi.org/10.1182/blood-2022-160263
Published: 2022
Journal Articles

DNMT3A/TET2 Mutant Clonal Hematopoiesis in Vexas Syndrome Results in DNA Hypomethylation and Transcriptional Activation of WT1 and MPL Oncogenic Pathways

Free
Jenna A. Fernandez, Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, Yael Kusne, Terra Lasho, Christy Finke, Matthew Koster, Abhishek A. Mangaonkar, Naseema Gangat, Kenneth Warrington, Kaaren K. Reichard, Horatiu Olteanu, Peter C. Grayson, Neal S. Young, David B. Beck, Mrinal M. Patnaik
Journal: Blood
Blood (2022) 140 (Supplement 1): 11410–11411.
https://doi.org/10.1182/blood-2022-167359
Published: 2022
Journal Articles

Monocytopenia As an Adverse Prognosticator in Vexas Syndrome

Free
Yael Kusne, Matthew Koster, Kenneth Warrington, Ronald Go, Terra Lasho, Christy Finke, Jenna A. Fernandez, Kebede Begna, Allison M. Bock, Kaaren K. Reichard, Horatiu Olteanu, Jennifer Herrick, Mrinal M.M. Patnaik
Journal: Blood
Blood (2022) 140 (Supplement 1): 11406–11407.
https://doi.org/10.1182/blood-2022-165706
Published: 2022
Journal Articles

Clinical Efficacy of JAK Inhibitors in Patients with Vexas Syndrome: A Multicenter Retrospective Study

Free
Maël Heiblig, Marcela A Ferrada, Mathieu Gerfaud-Valentin, Thomas Barba, Arsène Mékinian, Matthew Koster, Henrique Coelho, Gaelle Fossard, Fiorenza Barraco, Lionel Galicier, Boris Bienvenu, Pierre Hirsch, Guillaume Vial, Anne Blandine Boutin, Guillaume Le guenno, Adrien Bigot, Kenneth Warrington, Tanaz Kermani, Yvan Jamilloux, Peter C Grayson, Bhavisha A. Patel, David B. Beck, Pierre Fenaux, Pierre Sujobert
Journal: Blood
Blood (2021) 138 (Supplement 1): 2608.
https://doi.org/10.1182/blood-2021-150394
Published: 2021
Journal Articles

Histopathologic Characterization of Vexas Syndrome

Free
Mohammad I. Barouqa, Aishwarya Ravindran, Dong Chen, Jennifer L Oliveira, Horatiu Olteanu, Matthew T Howard, Gang Zheng, Mrinal M. Patnaik, Kebede H. Begna, Allison M. Bock, Ronald Go, Matthew Koster, Taxiarchis Kourelis, Abhishek A. Mangaonkar, Jay Ryu, Matthew Samec, Julio C. Sartori Valinotti, Kenneth Warrington, Kaaren K. Reichard
Journal: Blood
Blood (2021) 138 (Supplement 1): 4656.
https://doi.org/10.1182/blood-2021-152739
Published: 2021