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Journal Articles

Digestive complications in AML induction: Spotlight on neutropenic enterocolitis

Free
Ornesta Bezhani, Raphaël Pichois, Magalie Joris, Lydia Montes, Hélène Kemp, Amandine Charbonnier, Sylvain Chantepie, Emilie Lemasle, Jean Pierre Marolleau, Delphine Lebon
Journal: Blood
Blood (2025) 146 (Supplement 1): 8201.
https://doi.org/10.1182/blood-2025-8201
Published: 2025
Journal Articles

Only young age and genetics retain prognostic value for 2-year relapse-free survival in AML

Free
Wissam Mahrez, Céline Berthon, Laurene Fenwarth, Carine Hauspie, Nicolas Duployez, Claude Preudhomme, Magalie Joris, Jean Pierre Marolleau, Delphine Lebon
Journal: Blood
Blood (2025) 146 (Supplement 1): 3382.
https://doi.org/10.1182/blood-2025-3382
Published: 2025
Journal Articles

Outcome after relapse in older patients with Philadelphia Chromosome–Negative B-cell ALL treated with inotuzumab ozogamicin and low-dose chemotherapy in first-line therapy: A graall study

Free
Perrine Moyer, Thibaut Leguay, Francoise Huguet, Gabrielle Roth-Guepin, Yosr Hicheri, Amine Belhabri, Thomas Cluzeau, Ana Berceanu, Emmanuelle Tavernier, Stephane Lepretre, Karin Bilger, Pascal Turlure, Jean-Noel Bastie, Marie Balsat, Magda Alexis, Eolia Brissot, Delphine Lebon, Emmanuel Raffoux, Stefan Wickenhauser, Victoria Cacheux, Anne Banos, Sarah Bonnet, Nicolas Boissel, Herve Dombret, Maxime Jullien, Philippe Rousselot, Patrice Chevallier
Journal: Blood
Blood (2025) 146 (Supplement 1): 3340.
https://doi.org/10.1182/blood-2025-3340
Published: 2025
Journal Articles

Comprehensive mutational profiling and clinical outcome of adults AML with NUP98 rearrangement

Free
Ducourneau Benoit, Arnaud Pages, Stéphanie Struski, Matthieu Decamp, Emmanuel Raffoux, Céline Berthon, Laurene Fenwarth, Vincent Marmouset, Cecile Pautas, Thomas Cluzeau, Delphine Lebon, Madalina Uzunov, Patricio Pereyra, Mael Heiblig, Jean-Valère Malfuson, Laure Farnault, Pierre-Yves Dumas, Julia HIEULLE, Sarah Bertoli, Sylvain Chantepie, Nathalie Auger, Audrey Bidet, Marie Joelle Mozziconacci, Augustin Boudry, Isabelle Luquet, Laureen Chat, Romain Loyaux, Lina EL-MURR, Emmanuelle Clappier, Claude Gardin, Mathilde Hunault, Stephane De Botton, Arnaud Pigneux, Dominique Penther, Eric Delabesse, Raphael Itzykson, Claude Preudhomme, Herve Dombret, Christian Recher, Nicolas Duployez, Jean-Baptiste Micol
Journal: Blood
Blood (2025) 146 (Supplement 1): 7002.
https://doi.org/10.1182/blood-2025-7002
Published: 2025
Journal Articles

Ivosidenib in refractory or relapsed IDH1-mutated Acute Myeloid Leukemia patients in real life settings: The ivoobs observational study from the french AML intergroup ALFA/filo

Free
Mael Heiblig, Pierre Peterlin, Stéphane Morisset, Pierre-Yves Dumas, Marie Sebert, Sarah Bertoli, Paolo Musiu, Aurélie Ravinet, Sylvain Garciaz, Delphine Lebon, Pascal Turlure, Yohan Desbrosses, Juliette Lambert, Quentin Cabrera, Sarah Bonnet, Célestine Simand, Kamel Laribi, Anne Banos, Ambroise Marçais, Benjamin Carpentier, Adrien Daniel, Corentin Orvain, Thomas Cluzeau, Marlene Ochmann, Adrien Contejean, Cecile Pautas, Rudy Birsen, Benjamin Papoular, Celia Salanoubat, Jamilé Frayfer, Gianmatteo Pica, Julia HIEULLE, Nicolas Vallet, Ariane Mineur, Stephane De Botton, Christian Recher, Arnaud Pigneux
Journal: Blood
Blood (2025) 146 (Supplement 1): 3455.
https://doi.org/10.1182/blood-2025-3455
Published: 2025
Journal Articles

Diagnostic relevance of SH2B3 mutations in suspected myeloid malignancies: Insights from a large-scale NGS-based screening study

Free
Leïla BEN DHIA, Mathieu Wemeau, Laurene Fenwarth, Alice Marceau-Renaut, Elise Fournier, Ducourneau Benoit, Sabine Tricot, Manon Deschildt, Pascal Huchette, Stéphane DARRE, Ilyes BENHALIMA, Emilie MARGAT, Claire Bories, Maxime DUFOSSE, Thomas Boyer, Etienne Paubelle, Amandine Charbonnier, Delphine Lebon, Julia HIEULLE, Sophie Dennetiere, Zoé MALBRANQUE, Adrien Daniel, Judith BRUGE, Laurent Pascal, Jan BRIJS, Benjamin Carpentier, Alexandre Willaume, Valerie Coiteux, Laure Goursaud, Claude Preudhomme, Olivier NIBOUREL, Nicolas Duployez
Journal: Blood
Blood (2025) 146 (Supplement 1): 2016.
https://doi.org/10.1182/blood-2025-2016
Published: 2025
Journal Articles

Treatments and outcomes of adult patients with TP53-mutated acute myeloid leukemia (AML) in the real-life –Report of the prospective french observational ALFA-PPP study.

Free
Jean-Baptiste Micol, Raphael Itzykson, Laure Farnault, Thomas Cluzeau, Jean-Valère Malfuson, Sylvain Chantepie, Delphine Lebon, Claire Bories, Ramy Rahme, Mathieu Leclerc, Ahmad Aljijakli, Laurene Fenwarth, Alexandra COELHO, Renaud Buffet, Emmanuel Raffoux, Christophe Willekens, Marie Sebert, Stephane De Botton, Claude Preudhomme, Herve Dombret, Dominique Penther, Nicolas Duployez, Elsa Bernard
Journal: Blood
Blood (2025) 146 (Supplement 1): 6386.
https://doi.org/10.1182/blood-2025-6386
Published: 2025
Journal Articles

Real-world patterns of treatment intensity and prognostic model performance in older AML: Insights from the french ALFA-PPP cohort

Free
Lin-Pierre Zhao, Céline Berthon, Lauren Fenwarth, Stephane De Botton, Thomas Cluzeau, Laure Farnault, Sylvain Chantepie, Pierre Arnautou, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Ahmad Aljijakli, Isabelle Plantier, Ollivier Legrand, Juliette Lambert, Christophe Willekens, Emmanuel Raffoux, Claire Bories, Emilie Lemasle, Kevin-James Wattebled, Ambroise Marçais, Celia Salanoubat, Pascal Turlure, Jamilé Frayfer, Benjamin Carpentier, Madalina Uzunov, Reda Garidi, Ioana Vaida, Renaud Buffet, Alexandra COELHO, Karine Celli-Lebras, Raphael Itzykson, Claude Preudhomme, Nicolas Duployez, Hervé Dombret, Lionel Ades
Journal: Blood
Blood (2025) 146 (Supplement 1): 454.
https://doi.org/10.1182/blood-2025-454
Published: 2025
Journal Articles

Real life treatments and outcomes of older patients aged more than 60 years with FLT3-mutated acute myeloid leukemia: Report from the multicentric french observational ALFA-PPP study

Free
Ramy Rahmé, Emmanuel Raffoux, Lionel Ades, Stephane De Botton, Nicolas Duployez, Alexandra COELHO, Jean-Baptiste Micol, Sylvain Chantepie, Thomas Cluzeau, Delphine Lebon, Pierre Arnautou, Mathieu Leclerc, Laure Farnault, Ollivier Legrand, Ahmad Aljijakli, Céline Berthon, Juliette Lambert, Claire Bories, Ambroise Marçais, Julia HIEULLE, Celia Salanoubat, Pascal Turlure, Kevin-James Wattebled, Benjamin Carpentier, Jamile Frayfer, Ioana Vaida, Madalina Uzunov, Reda Garidi, Luca Inchiappa, Karine Celli-Lebras, Dominique Penther, Raynier Devillier, Raphael Itzykson, Claude Preudhomme, Renaud Buffet, Herve Dombret, Thorsten Braun
Journal: Blood
Blood (2025) 146 (Supplement 1): 449.
https://doi.org/10.1182/blood-2025-449
Published: 2025
Journal Articles

Outcomes of NPM1-mutated AMLs in first hematological relapse and prognostic value of MRD

Free
Sofiane Fodil, Matthieu Duchmann, Edoardo Tamellini, Anne Couprie, Rathana KIM, Pierre-Edouard Debureaux, Marie Passet, Nicolas Duployez, Etienne Lengline, Mattoe Dragani, Laureen Chat, Reinaldo Dal Bello, Matthieu Jestin, Lin-Pierre Zhao, Regis Peffault De Latour, Marie Sebert, Delphine Lebon, Nicolas Boissel, Lionel Ades, Emmanuelle Clappier, Emmanuel Raffoux, Raphael Itzykson
Journal: Blood
Blood (2025) 146 (Supplement 1): 5294.
https://doi.org/10.1182/blood-2025-5294
Published: 2025
Journal Articles

Impact of midostaurin in younger AML patients intensively treated with high-dose anthracycline

Free
Pierre-Yves Dumas, Mathieu Leclerc, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Thibaut Leguay, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Sylvain Chantepie, Mael Heiblig, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Delphine Lebon, Madalina Uzunov, Jean-Valère Malfuson, Thomas Cluzeau, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Eric Delabesse, Jean-François Hamel, Raphael Itzykson, Claude Preudhomme, Stephane De Botton, Nicolas Duployez, Arnaud Pigneux, Herve Dombret, Christian Recher
Journal: Blood
Blood (2025) 146 (Supplement 1): 1682.
https://doi.org/10.1182/blood-2025-1682
Published: 2025
Journal Articles

Real life study of ivosidenib in either monotherapy or combined with azacytidine for first line mutant IDH1 AML: A study from the french AML intergroup ALFA/filo

Free
Pierre Peterlin, Mael Heiblig, Stéphane Morisset, Sarah Bertoli, Marie Sebert, Thomas Cluzeau, Corentin Orvain, Pierre-Yves Dumas, Paolo Musiu, Sylvain Garciaz, Yohan Desbrosses, Gaspar Aspas Requena, Rudy Birsen, Pascal Turlure, Celestine Simand, Adrien Contejean, Celia Salanoubat, Benjamin Carpentier, Ambroise Marçais, Juliette Lambert, Delphine Lebon, Quentin Cabrera, Sarah Bonnet, Kamel Laribi, Anne Banos, Adrien Daniel, Marlene Ochmann, Cecile Pautas, Benjamin Papoular, Jamile Frayfer, Gian Matteo Pica, Julia HIEULLE, Nicolas Vallet, Ariane Mineur, Arnaud Pigneux, Christian Recher, Stephane De Botton
Journal: Blood
Blood (2025) 146 (Supplement 1): 1658.
https://doi.org/10.1182/blood-2025-1658
Published: 2025
Journal Articles

Secondary-type acute myeloid leukemia is associated with a higher risk of invasive fungal infection during intensive induction therapy. a correlative study on the ALFA 0702 trial.

Free
Jean-Eudes Fahrner, Mauricette Michallet, Laurene Fenwarth, Mohamad Sobh, Stéphane Morisset, Alexandre Deloire, Emmanuel Raffoux, Stephane De Botton, Sylvain Chantepie, Stephane Girault, Céline Berthon, Sarah Bertoli, Stephane Lepretre, Pierre Yves Dumas, Juliette Lambert, Delphine Lebon, Cecile Pautas, Jean Valère Malfuson, Norbert Vey, Thorsten Braun, Felipe Suarez, Aline Schmidt, Remy Gressin, Caroline Bonmati, Karine Celli-Lebras, Mael Heiblig, Mohamed El-Hamri, Claude Preudhomme, Hervé Dombret, Anne Bergeron, Nicolas Duployez, Raphael Itzykson
Journal: Blood
Blood (2025) 146 (Supplement 1): 994.
https://doi.org/10.1182/blood-2025-994
Published: 2025
Journal Articles

The addition of a tyrosine kinase inhibitor to intensive chemotherapy significantly improves outcome in de novo BCR::ABL1+ acute myeloid leukemia treated with intensive chemotherapy

Free
Sarah Bertoli, Niklas Landberg, Emilie Bérard, Camille Gondran, Laetitia Largeaud, Véronique De Mas, Pierre-Yves Dumas, Arnaud Pigneux, Audrey Bidet, Sylvain Garciaz, Ludovic Gabellier, Gabrielle Roth-Guepin, Corentin Orvain, Pierre Peterlin, Rudy Birsen, Magda Alexis, Martin Carre, Emmanuelle Tavernier, Marion Boissard Simonet, Chantal Himberlin, Marc Maynadié, Kamel Laribi, Cécile Moluçon-Chabrot, Amine Belhabri, Samy Chraibi, Quentin Cabrera, Delphine Lebon, Emmanuel Raffoux, Thomas Cluzeau, Jean-Baptiste Micol, Mathieu Leclerc, Céline Berthon, Herve Dombret, Gunnar Juliusson, Anna Robelius, Sören Lehmann, Martin Jädersten, Lovisa Wennström, Pau Montesinos, Carmen Botella, Juan Miguel Bergua Burgues, Raimundo Garcia, Josefina Serrano, Mariluz Amigo, Patricia Garcia Ramirez, Claudia Sossa, Juan Manuel Alonso-Dominguez, Hartmut Döhner, Konstanze Döhner, Daniela Späth, Michael Kühn, Claudia Lengerke, Hans-Jörg Tischler, Christoph Röllig, Leo Ruhnke, Christian Thiede, Andreas Burchert, Hubert Serve, Carsten Mueller-Tidow, Claudia Baldus, Jurjen Versluis, Peter Valk, Daniel Kristensen, Anne Stidsholt Roug, Jiri Mayer, Mika Kontro, Pia Ettala, Vladimir Lazarevic, Christian Recher
Journal: Blood
Blood (2025) 146 (Supplement 1): 991.
https://doi.org/10.1182/blood-2025-991
Published: 2025
Journal Articles

Induction chemotherapy with a single anthracycline-containing cycle in younger adults with newly diagnosed AML – the french backbone intergroup (BIG)-1 study on behalf of the filo, ALFA, and SFGM-TC study groups

Free
Christian Recher, Cecile Pautas, Sarah Bertoli, Pierre-Yves Dumas, Emmanuel Raffoux, Marie-Anne Hospital, Raja Prince-Eladnani, Mael Heiblig, Martin Carre, Sylvain Chantepie, Pierre Peterlin, Maria Pilar Gallego Hernanz, Juliette Lambert, Corentin Orvain, Romain Guieze, Pascal Turlure, Celestine Simand, Emilie Lemasle, Chantal Himberlin, Caroline Bonmati, Jean Valère Malfuson, Delphine Lebon, Thomas Cluzeau, Emmanuelle Tavernier, Jean-Baptiste Micol, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Anne Huynh, Thibaut Leguay, Isabelle Luquet, Dominique Penther, Nicolas Duployez, Eric Delabesse, Claude Preudhomme, Herve Dombret, Jean-François Hamel, Arnaud Pigneux, Hunault-Berger Mathilde
Journal: Blood
Blood (2025) 146 (Supplement 1): 43.
https://doi.org/10.1182/blood-2025-43
Published: 2025
Journal Articles

Therapy-related core binding factor Acute Myeloid Leukemia – a Study of the french acute leukemia intergroup

Free
Mathilde Chanut, Loïc Vasseur, Matthieu Duchmann, Pierre Hirsch, Céline Berthon, Mael Heiblig, Thorsten Braun, Mathieu Leclerc, Jean Valère Malfuson, Delphine Lebon, Madalina Uzunov, Jean-Noel Bastie, Gian Matteo Pica, Marie-Anne Hospital, Thomas Cluzeau, Juliette Lambert, Lauris Gastaud, Karine Celli-Lebras, Arnaud Pigneux, Stephane De Botton, Christian Recher, Claude Preudhomme, Eric Jourdan, Herve Dombret, Nicolas Boissel, Nicolas Duployez, Raphael Itzykson, Jean-Baptiste Micol
Journal: Blood
Blood (2025) 146 (Supplement 1): 37.
https://doi.org/10.1182/blood-2025-37
Published: 2025
Journal Articles

Pooled Fecal Allogenic Microbiotherapy for Refractory Gastrointestinal Acute Graft- Versus -Host Disease : Results from Early Access Program in Europe

Free
Florent Malard, Michael Loschi, Thomas Cluzeau, Raynier Devillier, Faezeh Legrand, Amandine Charbonnier, Delphine Lebon, Anne Huynh, Cecile Borel, Jean-Baptiste Méar, Faustine Lhomme, Hélène Labussière-Wallet, Déborah Desmier, Niels Moya, Martin Carré, Jérôme Cornillon, Vincent Camus, Patrice Ceballos, Francesco Saraceni, Corentin Orvain, Sylvain Chantepie, Jakob Daniel Rudzki, Marie-Anne Couturier, Patrice Chevallier, Clemence Mediavilla, Gabrielle Roth-Guepin, David Beauvais, Etienne Daguindau, Karin Bilger, Stefan A. Klein, Pedro Chorao, Sarah Altmeyer, Francesca Patriarca, Marion Bruelle, Emilie Plantamura, Gianfranco Pittari, Mohamad Mohty
Journal: Blood
Blood (2024) 144 (Supplement 1): 4903.
https://doi.org/10.1182/blood-2024-201251
Published: 2024
Journal Articles

Sequential Intensified Conditioning Regimen Allogeneic Transplantation in Younger Adult Patients with Adverse-Risk Acute Myeloid Leukemia: A Multi-Center Prospective Study from the Acute Leukemia French Intergroup on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Free
Regis Peffault de Latour, Edouard Forcade, Anne Huynh, Mathieu Leclerc, Stéphanie Nguyen Quoc, Patrice Ceballos, Jean-Baptiste Méar, Michael Loschi, Helene Labussiere-vallet, Jean-Henri Bourhis, Bruno Lioure, Ibrahim Yakoub-Agha, Jacques-Olivier Bay, Sylvie François, Claude-Éric Bulabois, Sylvain Chantepie, Marie-Thérèse Rubio, Patrice Chevallier, Anne Lise Mesnard, Delphine Lebon, Jean Valere Malfuson, Jérôme Cornillon, Etienne Daguindau, Pascal Turlure, Natacha Maillard, Alban Villate, Marie Robin, Nicole Raus, Jean-Yves Cahn, Arnaud Pigneux, Mathilde Hunault, Christian Recher, Hervé Dombret, Gerard Socie, Jean François Hamel, Raynier Devillier
Journal: Blood
Blood (2024) 144 (Supplement 1): 3483.
https://doi.org/10.1182/blood-2024-198603
Published: 2024
Journal Articles

Secondary Genetic Alterations and Measurable Residual Disease in Core Binding Factor Acute Myeloid Leukemia - a Study from the Acute Leukemia French Intergroup

Free
Loic Vasseur, Matthieu Duchmann, Nicolas Duployez, Emmanuel Raffoux, Celine Berthon, Mael Heiblig, Alexis Genthon, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Sylvain Chantepie, Jean-Baptiste Micol, Juliette Lambert, Christian Recher, Marie-Lorraine Chrétien, Thomas Cluzeau, Julien Vaidie, Jean-Valère Malfuson, Madalina Uzunov, Arnaud Pigneux, Pierre Peterlin, Sihem Tarfi, Pierre Hirsch, Dominique Penther, Eric Jourdan, Karine Celli-Lebras, Claude Preudhomme, Hervé Dombret, Jérôme Lambert, Nicolas Boissel, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 227.
https://doi.org/10.1182/blood-2024-194060
Published: 2024
Journal Articles

Treatments and Outcomes of Adult Patients with AML in the Real-Life - First Report of the French Observational ALFA-PPP Study

Free
Hervé Dombret, Alexandra Coelho, Laurène Fenwarth, Jean-Baptiste Micol, Lionel Ades, Thomas Cluzeau, Emmanuel Raffoux, Sylvain Chantepie, Pierre Arnautou, Mathieu Leclerc, Delphine Lebon, Thorsten Braun, Ollivier Legrand, Claire Bories, Céline Berthon, Juliette Lambert, Ahmad Aljijakli, Emilie Lemasle, Pascal Turlure, Benjamin Carpentier, Jamile Frayfer, Stephanie Haiat, Ambroise Marcais, Isabelle Plantier, Kevin-James Wattebled, Madalina Uzunov, Iona Vaida, Mael Heiblig, Lauris Gastaud, Laure Farnault, Dominique Penther, Nicole Raus, Renaud Buffet, Karine Celli-Lebras, Claude Preudhomme, Nicolas Duployez, Raphael Itzykson, Stephane De Botton
Journal: Blood
Blood (2024) 144 (Supplement 1): 2424.
https://doi.org/10.1182/blood-2024-207226
Published: 2024