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Journal Articles

Treatments and Outcomes of Adult Patients with AML in the Real-Life - First Report of the French Observational ALFA-PPP Study

Hervé Dombret, Alexandra Coelho, Laurène Fenwarth, Jean-Baptiste Micol, Lionel Ades, Thomas Cluzeau, Emmanuel Raffoux, Sylvain Chantepie, Pierre Arnautou, Mathieu Leclerc, Delphine Lebon, Thorsten Braun, Ollivier Legrand, Claire Bories, Céline Berthon, Juliette Lambert, Ahmad Aljijakli, Emilie Lemasle, Pascal Turlure, Benjamin Carpentier, Jamile Frayfer, Stephanie Haiat, Ambroise Marcais, Isabelle Plantier, Kevin-James Wattebled, Madalina Uzunov, Iona Vaida, Mael Heiblig, Lauris Gastaud, Laure Farnault, Dominique Penther, Nicole Raus, Renaud Buffet, Karine Celli-Lebras, Claude Preudhomme, Nicolas Duployez, Raphael Itzykson, Stephane De Botton
Journal: Blood
Blood (2024) 144 (Supplement 1): 2424.
https://doi.org/10.1182/blood-2024-207226
Published: 2024
Journal Articles

Pivekimab Sunirine (PVEK, IMGN632), a CD123-Targeting Antibody-Drug Conjugate, in Combination with Azacitidine and Venetoclax in Patients with Newly Diagnosed Acute Myeloid Leukemia

Naval Daver, Pau Montesinos, Jessica K. Altman, Eunice S. Wang, Giovanni Martinelli, Gail J. Roboz, Kebede Begna, Paresh Vyas, Monia Lunghi, Uwe Platzbecker, Patrick W. Burke, Roland B. Walter, Anjali S. Advani, Sylvain Garciaz, Lauris Gastaud, David A Sallman, Naveen Pemmaraju, Laura Torres, Yasmin Abaza, Onyee Chan, Hagop M. Kantarjian, Benjamin Oshrine, Yining Du, Kara Malcolm, Kendra Sweet
Journal: Blood
Blood (2023) 142 (Supplement 1): 2906.
https://doi.org/10.1182/blood-2023-173413
Published: 2023
Journal Articles

Venetoclax in Combination with Intermediate Doses of Cytarabine in Consolidation Phase for Acute Myeloid Leukemia Patients in First Complete Remission; Results of the Part 1 of the Phase 1/2 Multicentric Covenidac Study

Lauris Gastaud, Pierre Peterlin, Mathilde Hunault, Emmanuel Raffoux, Sarah Bertoli, Martin Carré, Cecile Pautas, Sylvain Chantepie, Juliette Lambert, Nicolas Duployez, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Vey, Arnaud Pigneux, Eric Delabesse, Claude Preudhomme, Adriana Plesa, Francois Vergez, Jean-François Hamel, Herve Dombret, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 4261.
https://doi.org/10.1182/blood-2023-173656
Published: 2023
Journal Articles

Long Term Outcomes and Renal Response Following Autologous Stem Cell Transplantation for Light Chain Deposition Disease:a Retrospective Study on Behalf of the Cmwp of the EBMT

Laurent Garderet, Luuk Gras, Sr., Linda Koster, Montserrat Rovira, Laure Vincent, Guido Kobbe, Srinivas Pillai, Dries Deeren, Martin Kaufmann, Jurgen Kuball, Hakan Ozdogu, Maria Jesús Pascual, Jakob R. Passweg, Adam Rye, Urpu Salmenniemi, John Snowden, Thomas Stauffer Larsen, Xavier Leleu, Lauris Gastaud, Joanna Drozd-Sokolowska, Kavita Raj, Meral Beksac, Stefan Schonland, Patrick John Hayden, Donal P McLornan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3403.
https://doi.org/10.1182/blood-2023-184367
Published: 2023
Journal Articles

Broad Activity for the Pivekimab Sunirine (PVEK, IMGN632), Azacitidine, and Venetoclax Triplet in High-Risk Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Naval Daver, Pau Montesinos, Ahmed Aribi, Giovanni Marconi, Jessica K. Altman, Eunice S. Wang, Gail J. Roboz, Patrick W. Burke, Gianluca Gaidano, Roland B. Walter, Xavier Thomas, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Elisabetta Todisco, Kebede H. Begna, Anjali Advani, Lauris Gastaud, Adolfo De La Fuente, Antonio Curti, Lourdes M. Mendez, Paresh Vyas, Nicolas Boissel, Norbert Vey, Christian Recher, Thomas Longval, Uwe Platzbecker, Silke Kapp-Schwoerer, Christoph Schliemann, Marina Konopleva, Laura Torres, David A. Sallman, Guido Marcucci, Naveen Pemmaraju, Giovanni Martinelli, Hagop Kantarjian, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2022) 140 (Supplement 1): 145–149.
https://doi.org/10.1182/blood-2022-158030
Published: 2022
Journal Articles

Therapy Related Myeloid Neoplasms Following PARP Inhibitors : Real-Life Experience

Vincent Marmouset, Justine Decroocq, Sylvain Garciaz, Gabriel Etienne, Amine Belhabri, Sarah Bertoli, Lauris Gastaud, Celestine Simand, Sylvain Chantepie, Madalina Uzunov, Alexis Genthon, Celine Berthon, Edmond Chiche, Pierre-Yves Dumas, Jacques Vargaftig, Géraldine Salmeron, Emilie Lemasle, Emmanuelle Tavernier, Jeremy Delage, Marion Loirat, Nadine Morineau, Felix Blanc-Durand, Patricia Pautier, Veronique Vergé, Nathalie Auger, Myrtille Thomas, Laetitia Stefani, Marion Lepelley, Thomas Boyer, Sylvain Thepot, Marie-Pierre Gourin, Pascal Bourquard, Matthieu Duchmann, Pierre Morice, Mauricette Michallet, Lionel Ades, Pierre Fenaux, Christian Recher, Hervé Dombret, Arnaud Pages, Christophe Marzac, Alexandra Leary, Jean-Baptiste Micol
Journal: Blood
Blood (2022) 140 (Supplement 1): 12335–12338.
https://doi.org/10.1182/blood-2022-163478
Published: 2022
Journal Articles

In Multiple Myeloma, High-Risk Secondary Genetic Events Observed at Relapse Are Present from the Diagnosis in Tiny Undetectable Subclones

Herve Avet-Loiseau, Romain Lannes, Aurore Perrot, Céline Mazzotti, Marion Divoux, Titouan Cazaubiel, Xavier Leleu, Anaïs Schavgoulidze, Marie-Lorraine Chretien, Salomon Manier, Didier Adiko, Frédérique Orsini-Piocelle, Francois Lifermann, Sabine Brechignac, Lauris Gastaud, Didier Bouscary, Magaret Macro, Mohamad Mohty, Nikhil C. Munshi, Jill Corre
Journal: Blood
Blood (2021) 138 (Supplement 1): 77.
https://doi.org/10.1182/blood-2021-146869
Published: 2021
Journal Articles

Replacing the Anthracycline By Gemtuzumab Ozogamicin in Older Patients with De Novo Standard-Risk Acute Myeloid Leukemia Treated Intensively - Results of the Randomized ALFA1401-Mylofrance 4 Study

Juliette Lambert, Jérôme Lambert, Emilie Lemasle, Magalie Joris, Sylvain Chantepie, Cecile Pautas, Xavier Thomas, Jean Valere Malfuson, Lauris Gastaud, Denis Caillot, Emmanuelle Tavernier, Pascal Turlure, Diana Carp, Celine Berthon, Olivier Legrand, Ambroise Marçais, Iona Vaida, Sarah Barbieux, Philippe Rousselot, Claude Gardin, Christine Terré, Nicolas Duployez, Claude Preudhomme, Karine Celli-Lebras, Sylvie Castaigne, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 31.
https://doi.org/10.1182/blood-2021-145152
Published: 2021
Journal Articles

A Phase 1b/2 Study of the CD123-Targeting Antibody-Drug Conjugate IMGN632 As Monotherapy or in Combination with Venetoclax and Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia

Naval Daver, Ahmed Aribi, Pau Montesinos, Gail J. Roboz, Eunice S. Wang, Roland B. Walter, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Anjali Advani, Patrick W. Burke, Giovanni Martinelli, Lauris Gastaud, Xavier Thomas, Jessica K. Altman, Lourdes M. Mendez, Adolfo de la Fuente, Elisabetta Todisco, Gianluca Gaidano, Antonio Curti, Nicolas Boissel, Christian Recher, Christoph Schliemann, Callum M Sloss, Jiuzhou Wang, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2021) 138 (Supplement 1): 4440.
https://doi.org/10.1182/blood-2021-146585
Published: 2021
Journal Articles

Retrospective Analysis of the Outcomes of Patients with Relapsed/Refractory Acute Myeloid Leukemia Included in a Patient Named Program of Gemtuzumab Ozogamicin

Juliette Lambert, Pierre Peterlin, Cecile Pautas, Emmanuel Raffoux, Denis Caillot, Ollivier Legrand, Magalie Joris, Anna Berceanu, Jean Valere Malfuson, Sylvain Chantepie, Marc Bernard, Lauris Gastaud, Arnaud Pigneux, Omar Benbrahim, Caroline Bonmati, Hunault-Berger Mathilde, Hervé Dombret, Philippe Rousselot, Sylvie Chevret, Sylvie Castaigne
Journal: Blood
Blood (2021) 138 (Supplement 1): 876.
https://doi.org/10.1182/blood-2021-145184
Published: 2021
Journal Articles

Safety and Efficacy from a Phase 1b/2 Study of IMGN632 in Combination with Azacitidine and Venetoclax for Patients with CD123-Positive Acute Myeloid Leukemia

Naval Daver, Ahmed Aribi, Pau Montesinos, Gail J. Roboz, Eunice S. Wang, Roland B. Walter, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Anjali Advani, Patrick W. Burke, Giovanni Martinelli, Lauris Gastaud, Xavier Thomas, Jessica K. Altman, Lourdes M. Mendez, Adolfo de la Fuente, Elisabetta Todisco, Gianluca Gaidano, Antonio Curti, Nicolas Boissel, Christian Recher, Christoph Schliemann, Marina Konopleva, David A. Sallman, Laura Torres, Guido Marcucci, Hagop Kantarjian, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2021) 138 (Supplement 1): 372.
https://doi.org/10.1182/blood-2021-146503
Published: 2021
Journal Articles

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

CME Clinical Trials & Observations
Raphael Itzykson, Elise Fournier, Céline Berthon, Christoph Röllig, Thorsten Braun, Alice Marceau-Renaut, Cécile Pautas, Olivier Nibourel, Emilie Lemasle, Jean-Baptiste Micol, Lionel Adès, Delphine Lebon, Jean-Valère Malfuson, Lauris Gastaud, Laure Goursaud, Emmanuel Raffoux, Kevin-James Wattebled, Philippe Rousselot, Xavier Thomas, Sylvain Chantepie, Thomas Cluzeau, Hubert Serve, Nicolas Boissel, Christine Terré, Karine Celli-Lebras, Claude Preudhomme, Christian Thiede, Hervé Dombret, Claude Gardin, Nicolas Duployez
Journal: Blood
Blood (2021) 138 (7): 507–519.
https://doi.org/10.1182/blood.2021011103
Published: 2021
Includes: Supplemental data
Journal Articles

Acute Myeloid Leukemia and Antifungal Prophylaxis Era: Compliance of AML Centers, Invasive Fungal Infection (IFI) Classification, IFI Incidence and AML Outcomes from ALFA 2007- 02 Study

Mauricette Michallet, MD PhD, Mohamad Sobh, PharmD, Stephane Morisset, BioStat, Alexandre Deloire, CRA, Emmanuel Raffoux, MD, Stephane De Botton, Denis Caillot, MD, Sylvain Chantepie, MD, Stephane Girault, MD, Celine Berthon, MD, Sarah Bertoli, MD PhD, Stephane Lepretre, Thibaut Leguay, MD, Sylvie Castaigne, MD, Jean-Pierre Marolleau, MD PhD, Cecile Pautas, MD, Jean Valère Malfuson, MD, Norbert Vey, MD PhD, Lauris Gastaud, Felipe Suarez, MD PhD, Aline Schmidt, MD, Rémy Gressin, MD, Caroline Bonmati, MD, Karine Celli-Lebras, CRA, Mohamed El-Hamri, CRA, Patricia Ribaud, MD, Herve Dombret, MD PhD, Xavier Thomas, MD PhD, Anne Bergeron
Journal: Blood
Blood (2019) 134 (Supplement_1): 2618.
https://doi.org/10.1182/blood-2019-130642
Published: 2019
Journal Articles

Oncogenic Predictors of Outcome in Older AML Patients Treated Intensively. Analysis of the ALFA-1200 Trial

Raphael Itzykson, MD PhD, Elise Fournier, Thorsten Braun, MD PhD, Céline Berthon, MD PhD, Alice Marceau-Renaut, Cecile Pautas, Olivier Nibourel, Emilie Lemasle, MD, Nicolas Duployez, PharmD, PhD, Jean-Baptiste Micol, MD PhD, Lionel Ades, MD PhD, Jean-Pierre Marolleau, MD PhD, Jean Valère Malfuson, MD, Lauris Gastaud, Emmanuel Raffoux, MD, Philippe Rousselot, MD, Xavier Thomas, MD, Sylvain Chantepie, MD, Thomas Cluzeau, MDPhD, Benjamin Papoular, Nicolas Boissel, MD PhD, Christine Terré, PharmD, PhD, Karine Celli-Lebras, CRA, Herve Dombret, MD, Claude Gardin, Claude Preudhomme
Journal: Blood
Blood (2018) 132 (Supplement 1): 993.
https://doi.org/10.1182/blood-2018-99-111144
Published: 2018
Journal Articles

Number of Mutations and Type of Prior Myeloproliferative Neoplasm Are Prognostic Factors in Acute Myeloid Leukemia Post Myeloproliferative Neoplasms

Edmond Chiche, Sarah Bonnet, Sarah Bertoli, MD PhD, Andrew T Kuykendall, MD, Lauris Gastaud, Pascal Boulay, Veronique De Mas, Eric Delabesse, MD PhD, Alice Marceau-Renaut, Claude Preudhomme, Anne Murati, David A Sallman, MD, S. Dominique Raynaud, MD, Christian Recher, MD PhD, Norbert Vey, MD PhD, Thomas Cluzeau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2806.
https://doi.org/10.1182/blood-2018-99-114428
Published: 2018
Journal Articles

Randomized Phase 2 Trial of Lirilumab (anti-KIR monoclonal antibody, mAb) As Maintenance Treatment in Elderly Patients (pts) with Acute Myeloid Leukemia (AML): Results of the Effikir Trial

Norbert Vey, Pierre-Yves Dumas, MD, Christian Recher, MD PhD, Lauris Gastaud, MD, Bruno Lioure, MD, Claude-Eric Bulabois, MD, Cecile Pautas, Jean-Pierre Marolleau, MD PhD, Stéphane Leprêtre, MD, Emmanuel Raffoux, MD, Xavier Thomas, MD, Yosr Hicheri, Caroline Bonmati, MD, Bruno Quesnel, MD PhD, Philippe Rousselot, Sylvie Castaigne, MD PhD, Eric Jourdan, MD, Jean Valère Malfuson, Gaelle Guillerm, MD, Jean Henri Bouhris, Mario Ojeda, MD, Mathilde Hunault, MD PhD, Norbert Ifrah, MD PhD, Claude Gardin, MD PhD, Andre Delannoy, MD, Lucile Beautier, Carine Paturel, PhD, Pascale Andre, PhD, Robert Zerbib, Claude Preudhomme, PharmD, PhD, Antoine Toubert, MD PhD, Nicolas Dulphy, PhD, Daniel Olive, MD PhD, Arnaud Pigneux, MD, Herve Dombret, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 889.
https://doi.org/10.1182/blood.V130.Suppl_1.889.889
Published: 2017
Journal Articles

Topotecan Plus Cytarabine Is an Effective and Safe Regimen for Newly Diagnosed and Adverse ELN-Risk Acute Myeloid Leukemia Subset in Patients with Cardiac Comorbidities

Clemence Marcault, MD, Geoffroy Venton, Lauris Gastaud, MD, Lionel Mannone, MD, Jerome Rey, MD, Evelyne D'Incan, MD, Colombe Saillard, MD, Aude Charbonnier, MD, Sophie Raynaud, MD PhD, Norbert Vey, Thomas Cluzeau, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2615.
https://doi.org/10.1182/blood.V130.Suppl_1.2615.2615
Published: 2017
Journal Articles

Clonal Selection in Therapy Related Myelodysplastic Syndromes Under Azacitidine Treatment

Anne Calleja, Chimene Moreilhon, PhD, Jean Michel Karsenti, MD, Lauris Gastaud, MD, Lionel Mannone, MD, Berengere Dadone, MD, Guillaume Robert, PhD, Patrick Auberger, PhD, Sophie Raynaud, MD PhD, Thomas Cluzeau, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5297.
https://doi.org/10.1182/blood.V130.Suppl_1.5297.5297
Published: 2017
Journal Articles

Role of Allogeneic Reduced Intensity Conditioning Stem Cell Transplantation (RIC-SCT) in Older Patients with Acute Myeloid Leukemia (AML): Analysis of the ALFA-1200 Study

Claude Gardin, Cécile Pautas, Emilie Lemasle, MD, Jean-Henri Bourhis, Lionel Ades, MD PhD, Jean-Pierre Marolleau, MD PhD, Jean Valère Malfuson, Lauris Gastaud, MD, Emmanuel Raffoux, MD, Isabel Cano, Thorsten Braun, MD PhD, Xavier Thomas, MD, Sylvain Chantepie, Thomas Cluzeau, MDPhD, Stephane De Botton, Céline Berthon, MD PhD, Benjamin Papoular, Nicolas Boissel, MD PhD, Claude Preudhomme, PharmD, PhD, Christine Terré, PharmD, PhD, Gérard Socié, MDPhD, Mauricette Michallet, MD PhD, Ibrahim Yakoub-Agha, Karine Celli-Lebras, CRA, Herve Dombret, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 466.
https://doi.org/10.1182/blood.V130.Suppl_1.466.466
Published: 2017
Journal Articles

Antifungal Prophylaxis in AML Patients Receiving Intensive Induction Chemotherapy. Prospective Observational Study from the Acute Leukemia French Association (ALFA) Group

Mauricette Michallet, MD PhD, Mohamad Sobh, PharmD, Alexandre Deloire, CRA, Emmanuel Raffoux, MD, Stephane de Botton, Denis Caillot, Oumedaly Reman, MD, Stephane Girault, MD, Celine Berthon, MD PhD, Francoise Huguet, MD, Stephane Lepretre, Thibaut Leguay, MD, Sylvie Castaigne, MD PhD, Bruno Royer, MD, Cecile Pautas, MD, Jean-Valere Malfuson, MD, Jose Fernandes, MD, Thomas Prebet, MD, Thorsten Braun, MD, Lauris Gastaud, MD, Felipe Suarez, MD PhD, Aline Schmidt, MD, Remy Gressin, MD, Jacques Delaunay, MD, Caroline Bonmati, MD, Karine Celli-Lebras, CRA, Mohamed El-Hamri, CRA, Herve Dombret, MD PhD, Xavier Thomas, MD PhD, Anne Bergeron, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3696.
https://doi.org/10.1182/blood.V128.22.3696.3696
Published: 2016