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Lourdes M. Mendez
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Journal Articles

Ppara Deletion Promotes Monocytic Leukemia Granulocytic Differentiation

Moussa Diolombi, Anish V Sharda, Ming Chen, Leinal Sejour, Assaf Bester, Daphna Nachmani, John G. Clohessy, Pier Paolo Pandolfi, Lourdes M Mendez
Journal: Blood
Blood (2024) 144 (Supplement 1): 4118.
https://doi.org/10.1182/blood-2024-211508
Published: 2024
Journal Articles

Efficacy and Safety of Pembrolizumab Added to Azacitidine Plus Venetoclax for Patients with Acute Myeloid Leukemia: Results from an Investigator-Initiated, Multi-Center, CTEP-Sponsored Randomized, Phase II Trial (BLAST AML-2)

Jessica M. Stempel, Geoffrey L. Uy, Shira N. Dinner, Ivana Gojo, Daniel Reed, Rupali Roy, Kenneth P Byrd, Swaroopa Yerrabothala, Catherine E. Lai, Kimberley Doucette, Anne Caldwell, Ondrej Blaha, Nikolai A. Podoltsev, Lourdes M Mendez, Jan Philipp Bewersdorf, Tariq Kewan, Ignacio Wistuba, Gheath Alatrash, Cara L Haymaker, Howard Streicher, Elad Sharon, Richard Little, Steven D. Gore, Jerald P. Radich, Brent L. Wood, Amer M. Zeidan, Rory M. Shallis
Journal: Blood
Blood (2024) 144 (Supplement 1): 736.
https://doi.org/10.1182/blood-2024-210370
Published: 2024
Journal Articles

ETV6 Mutations in Myeloid Neoplasia: Unraveling Clinical Features and Molecular Signatures

Tariq Kewan, Luisa Ladel, Ahmad Kiwan, Lourdes M Mendez
Journal: Blood
Blood (2024) 144 (Supplement 1): 4582.
https://doi.org/10.1182/blood-2024-211479
Published: 2024
Journal Articles

Phenotypic and Transcriptomic Profiling of MPN Endothelium

Salma A Abosabie, Lourdes M Mendez, Anish V Sharda
Journal: Blood
Blood (2024) 144 (Supplement 1): 1228.
https://doi.org/10.1182/blood-2024-211468
Published: 2024
Journal Articles

Ipilimumab plus decitabine for patients with MDS or AML in posttransplant or transplant-naïve settings

Clinical Trials & Observations
Jacqueline S. Garcia, Yael Flamand, Livius Penter, Michael Keng, Benjamin K. Tomlinson, Lourdes M. Mendez, Paul Koller, Nicole Cullen, Yohei Arihara, Kathleen Pfaff, Jacquelyn O. Wolff, Andrew M. Brunner, Ilene Galinsky, Asad Bashey, Joseph H. Antin, Corey Cutler, Vincent Ho, Brian A. Jonas, Marlise R. Luskin, Martha Wadleigh, Eric S. Winer, Alexandra Savell, Rebecca Leonard, Taylor Robertson, Matthew S. Davids, Howard Streicher, Scott J. Rodig, Jerome Ritz, Catherine J. Wu, Daniel J. DeAngelo, Donna Neuberg, Richard M. Stone, Robert J. Soiffer
Journal: Blood
Blood (2023) 141 (15): 1884–1888.
https://doi.org/10.1182/blood.2022017686
Published: 2023
Includes: Supplemental data
Journal Articles

Broad Activity for the Pivekimab Sunirine (PVEK, IMGN632), Azacitidine, and Venetoclax Triplet in High-Risk Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Naval Daver, Pau Montesinos, Ahmed Aribi, Giovanni Marconi, Jessica K. Altman, Eunice S. Wang, Gail J. Roboz, Patrick W. Burke, Gianluca Gaidano, Roland B. Walter, Xavier Thomas, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Elisabetta Todisco, Kebede H. Begna, Anjali Advani, Lauris Gastaud, Adolfo De La Fuente, Antonio Curti, Lourdes M. Mendez, Paresh Vyas, Nicolas Boissel, Norbert Vey, Christian Recher, Thomas Longval, Uwe Platzbecker, Silke Kapp-Schwoerer, Christoph Schliemann, Marina Konopleva, Laura Torres, David A. Sallman, Guido Marcucci, Naveen Pemmaraju, Giovanni Martinelli, Hagop Kantarjian, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2022) 140 (Supplement 1): 145–149.
https://doi.org/10.1182/blood-2022-158030
Published: 2022
Journal Articles

Safety and Efficacy from a Phase 1b/2 Study of IMGN632 in Combination with Azacitidine and Venetoclax for Patients with CD123-Positive Acute Myeloid Leukemia

Naval Daver, Ahmed Aribi, Pau Montesinos, Gail J. Roboz, Eunice S. Wang, Roland B. Walter, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Anjali Advani, Patrick W. Burke, Giovanni Martinelli, Lauris Gastaud, Xavier Thomas, Jessica K. Altman, Lourdes M. Mendez, Adolfo de la Fuente, Elisabetta Todisco, Gianluca Gaidano, Antonio Curti, Nicolas Boissel, Christian Recher, Christoph Schliemann, Marina Konopleva, David A. Sallman, Laura Torres, Guido Marcucci, Hagop Kantarjian, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2021) 138 (Supplement 1): 372.
https://doi.org/10.1182/blood-2021-146503
Published: 2021
Journal Articles

A Phase I Study of Asciminib (ABL001) in Combination with Dasatinib and Prednisone for BCR-ABL1-Positive ALL in Adults

Marlise R. Luskin, Kristen E. Stevenson, Lourdes M. Mendez, Eunice S. Wang, Martha Wadleigh, Jacqueline S. Garcia, Richard M. Stone, Hyun Hwan An, Ella Hagopian, Ilene Galinsky, Lindsey Rae, Rebecca Leonard, Daniel J. DeAngelo, Mark A. Murakami
Journal: Blood
Blood (2021) 138 (Supplement 1): 2305.
https://doi.org/10.1182/blood-2021-149225
Published: 2021
Journal Articles

Post-Transplant Vaccination with a Personalized Dendritic Cell/AML Fusion Cell Vaccine for Prevention of Relapse

Jessica J. Liegel, Poorva Bindal, Richard M. Stone, Robert J. Soiffer, Dina Stroopinsky, Giulia Cheloni, Lina Bisharat, Daniela Torres, Maryam Rahimian, Seo Yeon Yoo, Emma K. Logan, Pavania Elavalakanar, Hassan El Banna, Joshua Hauser, Anita G. Koshy, Rizwan Romee, Vincent T. Ho, Donna S. Neuberg, Yiwen Liu, Lourdes M. Mendez, Ajoy L. Dias, Benjamin L. Ebert, Donald Kufe, David Avigan, Jacalyn Rosenblatt
Journal: Blood
Blood (2021) 138 (Supplement 1): 2830.
https://doi.org/10.1182/blood-2021-154166
Published: 2021
Journal Articles

A Phase 1b/2 Study of the CD123-Targeting Antibody-Drug Conjugate IMGN632 As Monotherapy or in Combination with Venetoclax and Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia

Naval Daver, Ahmed Aribi, Pau Montesinos, Gail J. Roboz, Eunice S. Wang, Roland B. Walter, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Anjali Advani, Patrick W. Burke, Giovanni Martinelli, Lauris Gastaud, Xavier Thomas, Jessica K. Altman, Lourdes M. Mendez, Adolfo de la Fuente, Elisabetta Todisco, Gianluca Gaidano, Antonio Curti, Nicolas Boissel, Christian Recher, Christoph Schliemann, Callum M Sloss, Jiuzhou Wang, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2021) 138 (Supplement 1): 4440.
https://doi.org/10.1182/blood-2021-146585
Published: 2021
Journal Articles

Inhibition of ATR with AZD6738 (Ceralasertib) for the Treatment of Progressive or Relapsed Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: Safety and Preliminary Activity from a Phase Ib/II Study

Andrew M. Brunner, Yiwen Liu, Lourdes M. Mendez, Jacqueline S. Garcia, Philip C. Amrein, Donna S. Neuberg, Emma Dean, Simon Smith, Richard M. Stone, Amir T. Fathi, Matthew J. Walter, Timothy A. Graubert, Meagan A. Jacoby
Journal: Blood
Blood (2021) 138 (Supplement 1): 1521.
https://doi.org/10.1182/blood-2021-147301
Published: 2021
Journal Articles

VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2

Anish V. Sharda, Alexandra M. Barr, Joshua A. Harrison, Adrian R. Wilkie, Chao Fang, Lourdes M. Mendez, Ionita C. Ghiran, Joseph E. Italiano, Jr, Robert Flaumenhaft
Journal: Blood
Blood (2020) 136 (24): 2824–2837.
https://doi.org/10.1182/blood.2020005300
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Safety and Efficacy of Decitabine Plus Ipilimumab in Relapsed or Refractory MDS/AML in the Post-BMT or Transplant Naïve Settings

Jacqueline S. Garcia, MD, Yael Flamand, MS, Benjamin K. Tomlinson, MD, Michael Keng, MD, Lourdes M. Mendez, MD PhD, Samer Khaled, MD, Asad Bashey, MD PhD, Andrew M. Brunner, MD, Alexandra Savell, BS, Donna Neuberg, Ilene Galinsky, Marlise R. Luskin, MD, David P. Steensma, MD, Martha Wadleigh, MD, Eric S. Winer, MD, David E. Avigan, MD, Nicole Cullen, Scott Rodig, MD PhD, Livius Penter, R. Coleman Lindsley, MD PhD, Stephanie Andrews, Matthew S. Davids, MD, Catherine J. Wu, MD, Richard M. Stone, MD, Daniel J. DeAngelo, MD PhD, Robert J. Soiffer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–17.
https://doi.org/10.1182/blood-2020-136235
Published: 2020
Journal Articles

Vaccination with a Personalized Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in a Phase 1 Clinical Trial

Jessica Liegel, MD, Richard M. Stone, MD, Robert J. Soiffer, MD, Dina Stroopinsky, PhD, Lina Bisharat, Maryam Rahimian, Emma Logan, Pavania Elavalakanar, MSc, BSc, Vincent T. Ho, MD, Rizwan Romee, MD, Donna S. Neuberg, ScD, Yiwen Liu, Lourdes M. Mendez, MD PhD, Ajoy L. Dias, MD, Poorva Bindal, MD, Anita Koshy, MD, Shira Orr, PhD, Daniela Torres, Giulia Cheloni, PhD, Benjamin L. Ebert, MDPhD, Donald Kufe, MD, David E. Avigan, MD, Jacalyn Rosenblatt, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-141634
Published: 2020
Journal Articles

Aberrant rRNA 2'-O-Methylation Causes Bone Marrow Failure and Defective Immune Function

Daphna Nachmani, Lourdes M. Mendez, MD PhD, Pier Paolo Pandolfi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-141809
Published: 2020
Journal Articles

VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex

Anish V. Sharda, MBBS, MPH, Joshua Harrison, BS, Adrian R. Wilkie, PhD, Chao Fang, PhD, Lourdes M. Mendez, MD PhD, Joseph E. Italiano, Jr., BS, PhD, Robert C. Flaumenhaft, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 8.
https://doi.org/10.1182/blood-2019-127712
Published: 2019
Journal Articles

Ex-Vivo Stimulation with DC/AML Fusion Vaccine in the Presence of Cytokines Leads to an Activated T Cell Memory Phenotype and Enhanced Cytotoxicity with Potential for Use As an Adoptive Cellular Therapy

Jessica Liegel, MD, Dina Stroopinsky, PhD, Lourdes M. Mendez, MD PhD, Malgorzata McMasters, MD, Haider Ghiasuddin, BA, Maryam Rahimian, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Salvia Jain, MD, Marzia Capelletti, PhD MMSc, Lina Bisharat, MA, Adam Morin, BA, Shira Orr, PhD, Jacalyn Rosenblatt, MD, Donald Kufe, MD, David E. Avigan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2728.
https://doi.org/10.1182/blood-2018-99-119996
Published: 2018
Journal Articles

Induction Therapy for Gamma-Heavy Chain Disease with Bortezomib and Dexamethasone: A Case Report

Jon E. Arnason, MD, Lourdes M. Mendez, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 5051.
https://doi.org/10.1182/blood.V120.21.5051.5051
Published: 2012
Journal Articles

Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas

B. Belinda Ding, J. Jessica Yu, Raymond Y.-L. Yu, Lourdes M. Mendez, Rita Shaknovich, Yonghui Zhang, Giorgio Cattoretti, B. Hilda Ye
Journal: Blood
Blood (2008) 111 (3): 1515–1523.
https://doi.org/10.1182/blood-2007-04-087734
Published: 2008
Includes: Supplemental data
Journal Articles

CtBP1 Is a Novel and Essential Corepressor for BCL6 Autoregulation.

Lourdes M. Mendez, Jose Polo, Melissa Krupski, Jessica Yu, Ari M. Melnick, MD, B.H. Ye, PhD
Journal: Blood
Blood (2007) 110 (11): 3581.
https://doi.org/10.1182/blood.V110.11.3581.3581
Published: 2007