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Journal Articles

The C553-C581 Disulfide of Human Factor XI Is Crucial for Its Activation and Is Targeted By Thiol Isomerase Pdir

Yuxin Zhang, Shuo Liu, Zhenzhen Zhao, Keyu Lv, Chao Fang, Yue Han, Juhong Wu, Depei Wu, Jingyu Zhang, Aizhen Yang, Yi Wu

Blood (2024) 144 (Supplement 1): 1200.

https://doi.org/10.1182/blood-2024-204517

Published: 2024

Journal Articles

Transmembrane Thiol Isomerase TMX1 Inhibits Fibrin Formation By Down-Regulation of Platelet Phosphatidylserine Exposure

Zhenzhen Zhao, Keyu Lv, Yixin Cheng, Chao Fang, Yi Wu, Aizhen Yang

Blood (2024) 144 (Supplement 1): 5466.

https://doi.org/10.1182/blood-2024-203314

Published: 2024

Journal Articles

VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2

Anish V. Sharda, Alexandra M. Barr, Joshua A. Harrison, Adrian R. Wilkie, Chao Fang, Lourdes M. Mendez, Ionita C. Ghiran, Joseph E. Italiano, Jr, Robert Flaumenhaft

Blood (2020) 136 (24): 2824–2837.

https://doi.org/10.1182/blood.2020005300

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Extracellular Protein Disulfide Isomerase Cleaves Allosteric Disulfides in Histidine-Rich Glycoprotein to Regulate Thrombus Formation

Shuai Chen, M.S., Xu-Lin Xu, PhD, Joyce Chiu, PhD, Sheryl Bowley, PhD, Yi Wu, MD, PhD, Philip J. Hogg, PhD, Chao Fang, PhD

Blood (2020) 136 (Supplement 1): 11–12.

https://doi.org/10.1182/blood-2020-137810

Published: 2020

Journal Articles

VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex

Anish V. Sharda, MBBS, MPH, Joshua Harrison, BS, Adrian R. Wilkie, PhD, Chao Fang, PhD, Lourdes M. Mendez, MD PhD, Joseph E. Italiano, Jr., BS, PhD, Robert C. Flaumenhaft, MD PhD

Blood (2019) 134 (Supplement_1): 8.

https://doi.org/10.1182/blood-2019-127712

Published: 2019

Journal Articles

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Chao Fang, PhD, Anish V. Sharda, MBBS, MPH, Lin Lin, PhD, Robert C. Flaumenhaft, MD PhD, Bruce Furie, MD

Blood (2017) 130 (Supplement 1): 442.

https://doi.org/10.1182/blood.V130.Suppl_1.442.442

Published: 2017

Journal Articles

Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation

Chao Fang, PhD, Sheryl R. Bowley, PhD, Barbara C. Furie, PhD, Bruce Furie, MD

Blood (2016) 128 (22): 15.

https://doi.org/10.1182/blood.V128.22.15.15

Published: 2016

Journal Articles

Leukocyte XII Regulates Venous Thrombosis Risk

Evi X. Stavrou, MD, Chao Fang, PhD, Alona A. Merkulova, M.S., Lalitha V. Nayak, MD, Howard Meyerson, MD, Alvin H. Schmaier, MD

Blood (2015) 126 (23): 238.

https://doi.org/10.1182/blood.V126.23.238.238

Published: 2015

Journal Articles

Reduced thrombosis in Klkb1 −/− mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor

Evi X. Stavrou, Chao Fang, Alona Merkulova, Omar Alhalabi, Nadja Grobe, Silvio Antoniak, Nigel Mackman, Alvin H. Schmaier

Blood (2015) 125 (4): 710–719.

https://doi.org/10.1182/blood-2014-01-550285

Published: 2015

Includes: Supplemental data

Journal Articles

Thrombosis Protection In Klkb1 -/- (Prekallikrein KO) Mice Is Mediated By Increased Renal Mas Receptor, Plasma Prostacyclin, and Aortic Sirt1

Chao Fang, Evi Stavrou, MD, Yunmei Wang, PhD, Nadja Grobe, PhD, Daniel I. Simon, MD, Alvin H. Schmaier, MD

Blood (2013) 122 (21): 195.

https://doi.org/10.1182/blood.V122.21.195.195

Published: 2013

Journal Articles

Prolylcarboxypeptidase promotes angiogenesis and vascular repair

Gregory N. Adams, Evi X. Stavrou, Chao Fang, Alona Merkulova, M. Amer Alaiti, Kohsuke Nakajima, Toshifumi Morooka, Sergei Merkulov, Gretchen A. LaRusch, Daniel I Simon, Mukesh K. Jain, Alvin H. Schmaier

Blood (2013) 122 (8): 1522–1531.

https://doi.org/10.1182/blood-2012-10-460360

Published: 2013

Includes: Supplemental data

Journal Articles

Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2 −/− mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation

Chao Fang, Evi Stavrou, Alec A. Schmaier, Nadja Grobe, Mariana Morris, Andrew Chen, Marvin T. Nieman, Gregory N. Adams, Gretchen LaRusch, Yihua Zhou, Matthew L. Bilodeau, Fakhri Mahdi, Mark Warnock, Alvin H. Schmaier

Blood (2013) 121 (15): 3023–3032.

https://doi.org/10.1182/blood-2012-09-459156

Published: 2013

Includes: Supplemental data

Journal Articles

Leukocyte Factor XII Mediates Inflammation and Its Deficiency Promotes Wound Healing

Evi Stavrou, MD, Matthew J. Fullana, Gretchen LaRusch, Cindy Yushin Chang, Chao Fang, Howard J. Meyerson, Cheng-Kui Qu, Wen-Mei Yu, Gary E. Wnek, Alvin H. Schmaier, MD

Blood (2012) 120 (21): 616.

https://doi.org/10.1182/blood.V120.21.616.616

Published: 2012

Journal Articles

Factor XII Promotes Leukocyte Inflammation and Its Deficiency Results in Faster Wound Healing

Evi Stavrou, MD, Gretchen A. LaRusch, Matthew J. Fullana, Gary E. Wnek, Cheng-Kui Qu, Wen-Mei Yu, Howard J. Meyerson, Chao Fang, Nicholas P. Ziats, Alvin H. Schmaier, MD

Blood (2011) 118 (21): 368.

https://doi.org/10.1182/blood.V118.21.368.368

Published: 2011

Journal Articles

Over-Expression of the Mas Receptor Decreases Arterial Thrombosis Risk in B2R KO Mice by Elevating NO and Prostacyclin and Reducing GPVI Activation

Chao Fang, Evi Stavrou, MD, Alec A Schmaier, PhD, Gregory N Adams, Marvin T. Nieman, PhD, Gretchen LaRusch, Matthew Bilodeau, MD, PhD, Fakhri Mahdi, Mark Warnock, Alvin H. Schmaier, MD

Blood (2011) 118 (21): 700.

https://doi.org/10.1182/blood.V118.21.700.700

Published: 2011

Journal Articles

Bradykinin B2 Receptor KO Mice Are Protected From Thrombosis by A Platelet Spreading Defect

Chao Fang, Alec Schmaier, PhD, Evi Stavrou, MD, Gregory Adams, Marvin T. Nieman, PhD, Gretchen LaRusch, Andrew Chen, MD, Yihua Zhou, Matthew Bilodeau, MD, PhD, Fakhri Mahdi, MD, Mark Warnock, Alvin H. Schmaier, MD

Blood (2010) 116 (21): 3198.

https://doi.org/10.1182/blood.V116.21.3198.3198

Published: 2010

NARROW

The C553-C581 Disulfide of Human Factor XI Is Crucial for Its Activation and Is Targeted By Thiol Isomerase Pdir

Transmembrane Thiol Isomerase TMX1 Inhibits Fibrin Formation By Down-Regulation of Platelet Phosphatidylserine Exposure

VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2

Extracellular Protein Disulfide Isomerase Cleaves Allosteric Disulfides in Histidine-Rich Glycoprotein to Regulate Thrombus Formation

VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation

Leukocyte XII Regulates Venous Thrombosis Risk

Reduced thrombosis in Klkb1 −/− mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor

Thrombosis Protection In Klkb1 -/- (Prekallikrein KO) Mice Is Mediated By Increased Renal Mas Receptor, Plasma Prostacyclin, and Aortic Sirt1

Prolylcarboxypeptidase promotes angiogenesis and vascular repair

Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2 −/− mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation

Leukocyte Factor XII Mediates Inflammation and Its Deficiency Promotes Wound Healing

Factor XII Promotes Leukocyte Inflammation and Its Deficiency Results in Faster Wound Healing

Over-Expression of the Mas Receptor Decreases Arterial Thrombosis Risk in B2R KO Mice by Elevating NO and Prostacyclin and Reducing GPVI Activation

Bradykinin B2 Receptor KO Mice Are Protected From Thrombosis by A Platelet Spreading Defect

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