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Journal Articles

The C553-C581 Disulfide of Human Factor XI Is Crucial for Its Activation and Is Targeted By Thiol Isomerase Pdir

Yuxin Zhang, Shuo Liu, Zhenzhen Zhao, Keyu Lv, Chao Fang, Yue Han, Juhong Wu, Depei Wu, Jingyu Zhang, Aizhen Yang, Yi Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1200.
https://doi.org/10.1182/blood-2024-204517
Published: 2024
Journal Articles

iPSC-Derived CAR-Gamma Delta T with Novel Combinatorial KO Demonstrated Extended Longevity and Profound Anti-Tumor Efficacy without Cytokine Support in Preclinical Studies

Jhang-Sian Yu, Chia-Hung Lin, Ying-Tsen Tung, Fang-Pei Chang, Edward Po-Fan Chu, Shiou-Ling Jian, Fu-Fei Hsu, Ming-Chin Ko, Yi-Han Dai, Chieh-Teng Cheng, Tzu-Chien Kuo, I-Ting Chen, Ting-Yi Wu, Jin-Yi Lu, Ke-Hsun Hsu, Wei-Ting Chen, Darien Zhing Herr Chan, Yi-Ting Lai, Shao-Ju Weng, Liang-Yi Chen, Yuan-Yu Hsia, Yi-Hung Ou, Yo-Chuen Lin, Shih-Wen Huang, Yu-Chih Peng, Chien-Hsi Chen, Chien-Yu Hsu, Yi-Ting Lai, Chih-Lung Chen, Chun-Yu Lin, Lin-Yu Liao, Wan-Chen Tsai, Hsin-Hua Cho, Cheng-Kai Wang, Lee-Yieng Lim, Ji-Kuan Wang, Yao-Yu Chen, Chih-Kai Yin, Wen-Hao Wang, Tsung-Hao Yeh, Min-Ren Chiang, Ruyue Ji, Jen-Chih Chi, Lien-Szu Wu, Jennifer Huang, De-Kuan Chang, Alex Shih-Min Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4790.
https://doi.org/10.1182/blood-2024-205086
Published: 2024
Journal Articles

Discovery of the Unique GMP-Grade iPSC Clones That Give Rise to Functional, High Purity, Matured CD8 Alpha Beta T or Gamma Delta T with Exponential Expansion Capacity

Ying-Tsen Tung, Chih-Lung Chen, Annie Yi-Ting Lai, Chien-Yu Hsu, Chien-Hsi Chen, Po-Fan Chu, Lin-Yu Liao, Tzu-Chien Kuo, Chieh-Teng Cheng, Chun-Yu Lin, Wan-Chen Tsai, Wei-Ting Chen, Darien Zhing Herr Chan, Hsin-Hua Cho, Cheng-Kai Wang, Yo-Chuen Lin, Jin-Yi Lu, Lee-Yieng Lim, Jhang-Sian Yu, Ming-Chin Ko, Chia-Hung Lin, Yi-Han Dai, I-Ting Chen, Fang-Pei Chang, Shao-Ju Weng, Ting-Yi Wu, Yuan-Yu Hsia, Fu-Fei Hsu, Lillian Yi-Ting Lai, Shiou-Ling Jian, Shih-Wen Huang, Yu-Chih Peng, Ke-Hsun Hsu, Liang-Yi Chen, Ji-Kuan Wang, Yao-Yu Chen, Chih-Kai Yin, Yi-Hung Ou, Min-Ren Chiang, Wen-Hao Wang, Tsung-Hao Yeh, Xiaming Peng, Yang Shi, Pei Zhang, Ya-Chu Yu, Yun Gao, Yen-Hsien Lee, Pei-Chun Wu, Ta-Hsun Liao, De-Kuan Chang, Lien-Szu Wu, Jen-Chih Chi, Ching-Ying Huang, Alex Shih-Min Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7195.
https://doi.org/10.1182/blood-2024-203106
Published: 2024
Journal Articles

Transmembrane Thiol Isomerase TMX1 Inhibits Fibrin Formation By Down-Regulation of Platelet Phosphatidylserine Exposure

Zhenzhen Zhao, Keyu Lv, Yixin Cheng, Chao Fang, Yi Wu, Aizhen Yang
Journal: Blood
Blood (2024) 144 (Supplement 1): 5466.
https://doi.org/10.1182/blood-2024-203314
Published: 2024
Journal Articles

A novel role for endoplasmic reticulum protein 46 (ERp46) in platelet function and arterial thrombosis in mice

Junsong Zhou, Yi Wu, Lubica Rauova, Gavin Koma, Lu Wang, Mortimer Poncz, Hong Li, Tong Liu, Karen P. Fong, Joel S. Bennett, Satya P. Kunapuli, David W. Essex
Journal: Blood
Blood (2022) 139 (13): 2050–2065.
https://doi.org/10.1182/blood.2021012055
Published: 2022
Includes: Supplemental data
Journal Articles

Plasmin taking contact pathway to inflame liver

Yi Wu
Journal: Blood
Blood (2021) 138 (3): 208–209.
https://doi.org/10.1182/blood.2021011853
Published: 2021
Journal Articles

Extracellular Protein Disulfide Isomerase Cleaves Allosteric Disulfides in Histidine-Rich Glycoprotein to Regulate Thrombus Formation

Shuai Chen, M.S., Xu-Lin Xu, PhD, Joyce Chiu, PhD, Sheryl Bowley, PhD, Yi Wu, MD, PhD, Philip J. Hogg, PhD, Chao Fang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-137810
Published: 2020
Journal Articles

The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses

Brief Report
Zhenzhen Zhao, Yi Wu, Junsong Zhou, Fengwu Chen, Aizhen Yang, David W. Essex
Journal: Blood
Blood (2019) 133 (3): 246–251.
https://doi.org/10.1182/blood-2018-04-844480
Published: 2019
Includes: Supplemental data
Journal Articles

Coagulation Factor XII Plays an Important Role in Procoagulant Activity of Apoptotic Cells

Aizhen Yang, Yi Wu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2457.
https://doi.org/10.1182/blood-2018-99-118223
Published: 2018
Journal Articles

The disulfide isomerase ERp72 supports arterial thrombosis in mice

Junsong Zhou, Yi Wu, Fengwu Chen, Lu Wang, Lubica Rauova, Vincent M. Hayes, Mortimer Poncz, Hong Li, Tong Liu, Junling Liu, David W. Essex
Journal: Blood
Blood (2017) 130 (6): 817–828.
https://doi.org/10.1182/blood-2016-12-755587
Published: 2017
Includes: Supplemental data
Journal Articles

The Second CGHC Motif of Protein Disulfide Isomerase Mediates Thrombosis

Junsong Zhou, BS, Yi Wu, Lu Wang, BS, Lubica Rauova, MD PhD, Vincent M Hayes, BS, Mortimer Poncz, MD, David W Essex, MD
Journal: Blood
Blood (2015) 126 (23): 1032.
https://doi.org/10.1182/blood.V126.23.1032.1032
Published: 2015
Journal Articles

Bradykinin Receptors Regulate Proliferation, Migration and Tube Formation of Endothelial Progenitor Cells

Yi Wu, Nadia Backdash, Robert W. Colman
Journal: Blood
Blood (2014) 124 (21): 4176.
https://doi.org/10.1182/blood.V124.21.4176.4176
Published: 2014
Journal Articles

Platelet-derived ERp57 mediates platelet incorporation into a growing thrombus by regulation of the αIIbβ3 integrin

Lu Wang, Yi Wu, Junsong Zhou, Syed S. Ahmad, Bulent Mutus, Natalio Garbi, Günter Hämmerling, Junling Liu, David W. Essex
Journal: Blood
Blood (2013) 122 (22): 3642–3650.
https://doi.org/10.1182/blood-2013-06-506691
Published: 2013
Includes: Supplemental data
Journal Articles

Platelet-Derived ERp57 Mediates Platelet Incorporation Into a Growing Thrombus By Regulation Of The αIIbβ3 Integrin

Lu Wang, Yi Wu, Junsong Zhou, Syed S. Ahmad, Bulent Mutus, Natalio Garbi, Gunter Hammerling, David W Essex, MD
Journal: Blood
Blood (2013) 122 (21): 3505.
https://doi.org/10.1182/blood.V122.21.3505.3505
Published: 2013
Journal Articles

PDK1 regulates platelet activation and arterial thrombosis

Xue Chen, Yue Zhang, Yanhua Wang, Ding Li, Lin Zhang, Kemin Wang, Xinping Luo, Zhongzhou Yang, Yi Wu, Junling Liu
Journal: Blood
Blood (2013) 121 (18): 3718–3726.
https://doi.org/10.1182/blood-2012-10-461897
Published: 2013
Journal Articles

Platelet ERp57 Is Required for Hemostasis and Thrombosis.

Lu Wang, Yi Wu, MD, PhD, Junsong Zhou, Syed S. Ahmad, MD, PhD, Bulent Mutus, David W Essex, MD
Journal: Blood
Blood (2012) 120 (21): 2168.
https://doi.org/10.1182/blood.V120.21.2168.2168
Published: 2012
Journal Articles

Cleaved High Molecular Weight Kininogen Induces Endothelial Progenitor Cell Senescence by Stimulation of JNK/FOXO4/MnSOD Pathway.

Xuemei Zhu, Robert W. Colman, Yi Wu
Journal: Blood
Blood (2012) 120 (21): 2181.
https://doi.org/10.1182/blood.V120.21.2181.2181
Published: 2012
Journal Articles

The disulfide isomerase ERp57 mediates platelet aggregation, hemostasis, and thrombosis

Yi Wu, Syed S. Ahmad, Junsong Zhou, Lu Wang, Matthew P. Cully, David W. Essex
Journal: Blood
Blood (2012) 119 (7): 1737–1746.
https://doi.org/10.1182/blood-2011-06-360685
Published: 2012
Journal Articles

Gas6 Receptors, Tyro3, Axl and Mer, Differentially Participate in Glycoprotein VI-Mediated Platelet activation

Junsong Zhou, Lu Wang, Yi Wu
Journal: Blood
Blood (2011) 118 (21): 364.
https://doi.org/10.1182/blood.V118.21.364.364
Published: 2011
Journal Articles

The Disulfide Isomerase Erp57 Mediates Platelet Aggregation and Hemostasis

Yi Wu, MD, PhD, Syed S. Ahmad, MD, PhD, Junsong Zhou, Lu Wang, Matthew P Cully, David W Essex, MD
Journal: Blood
Blood (2011) 118 (21): 1129.
https://doi.org/10.1182/blood.V118.21.1129.1129
Published: 2011