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Journal Articles

Genetic Determinants of Clonal Hematopoiesis and Progression to Hematologic Malignancies in 479,117 Individuals

Jie Liu, Duc Tran, Irenaeus C.C. Chan, Brian Wiley, Caroline Watson, Armel L. Batchi-Bouyou, Xiaoyu Zong, Konrad H. Stopsack, Paul Pharoah, Li Ding, Jamie R Blundell, Yin Cao, Matthew J. Walter, Nilanjan Chatterjee, Kenneth Offit, Lucy Godley, Daniel C. Link, Zsofia Stadler, Kelly L. Bolton

Blood (2023) 142 (Supplement 1): 811.

https://doi.org/10.1182/blood-2023-182423

Published: 2023

Journal Articles

Reduced Subclone Diversity in Clonal Cytopenia of Undetermined Significance Compared to Myelodysplastic Syndrome

Monique Chavez, Sridhar N Srivatsan, Christopher A Miller, Andrew J. Menssen, Ajay Khanna, Jin Shao, Catrina Fronick, Robert Fulton, Sharon E Heath, Constantine Logothetis, Tasha Burton, Victoria Donaldson, Claudia Cabrera, Raya Saba, Kiran R. Vij, Eric J. Duncavage, Meagan Jacoby, Matthew J. Walter

Blood (2023) 142 (Supplement 1): 2696.

https://doi.org/10.1182/blood-2023-189591

Published: 2023

Journal Articles

Primary U2AF1 S34F Mutated Hematopoietic Cells Are Sensitive to Nonsense-Mediated RNA Decay Disruption In Vivo

Claudia Cabrera, Sridhar N Srivatsan, Abigael Cheruiyot, Tanzir Ahmed, Zheng Yang, Jin Shao, Monique Chavez, Sarah Grieb, Julie Bailis, Zhongsheng You, Matthew J. Walter

Blood (2023) 142 (Supplement 1): 43.

https://doi.org/10.1182/blood-2023-181984

Published: 2023

Journal Articles

Plasma Proteomic Signature Predicts Risk of Myeloid Neoplasm

J. Scott Beeler, Duc Tran, Jie Liu, Zilan Xin, Brian Wiley, Irenaeus C.C. Chan, Michael H. Kramer, Armel L. Batchi-Bouyou, Xiaoyu Zong, Matthew J. Walter, Sarantis Chlamydas, Francesca Ferraro, Stephen T. Oh, Ben Busby, Daniel C. Link, Yin Cao, Kelly L. Bolton

Blood (2023) 142 (Supplement 1): 940.

https://doi.org/10.1182/blood-2023-190857

Published: 2023

Journal Articles

Correlation between Peripheral Blood and Bone Marrow Somatic Mutations Among Patients with Suspected or Established Myelodysplastic Syndromes from the National MDS Study

Amy E. DeZern, Johannes Goll, Travis L Jensen, Sridhar N Srivatsan, Nancy K Gillis, Gregory A Abel, Eric Padron, H. Joachim Deeg, Tareq Al Baghdadi, Jane Lijun Liu, Rami S. Komrokji, Steven D. Gore, Wael Saber, Rafael Bejar, Matthew J. Walter, Seth Sherman, Nancy DiFronzo, Mikkael A. Sekeres

Blood (2023) 142 (Supplement 1): 1860.

https://doi.org/10.1182/blood-2023-178587

Published: 2023

Journal Articles

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia

Blood (2022) 140 (21): 2228–2247.

https://doi.org/10.1182/blood.2022015853

Published: 2022

Includes: Supplemental data

Journal Articles

Nonsense-Mediated RNA Decay Disruption Induces Altered Splicing in Spliceosome Mutant Cells

Claudia Cabrera, Sridhar Nonavinkere Srivatsan, Abigael Cheruiyot, Tanzir Ahmed, Zheng Yang, Jin J Shao, Monique Chavez, Julie Bailis, Zhongsheng You, Matthew J Walter

Blood (2022) 140 (Supplement 1): 6907–6908.

https://doi.org/10.1182/blood-2022-160373

Published: 2022

Journal Articles

Spatial Organization of Hematopoietic Clones in the Bone Marrow of a Patient with Polycythemia Vera

Andrew L Young, Hannah C Davis, David H Spencer, Timothy J Ley, Stephen T Oh, Matthew J Walter, Grant A Challen

Blood (2022) 140 (Supplement 1): 2910–2911.

https://doi.org/10.1182/blood-2022-167351

Published: 2022

Journal Articles

Phase I Study of Baricitinib Gvhd Prophylaxis in HLA-Matched, Peripheral Blood Allogeneic Hematopoietic Cell Transplant

Blood (2022) 140 (Supplement 1): 1875–1876.

https://doi.org/10.1182/blood-2022-157214

Published: 2022

Journal Articles

Dynamics of Mortality and Transformation Risk within Different Risk Groups of Patients with Myelodysplastic Syndromes Stratified According to the IPSS-R - Comparison of Treated and Untreated Patients and Consequences for the Description of Risk Categories

Blood (2022) 140 (Supplement 1): 6976–6978.

https://doi.org/10.1182/blood-2022-158671

Published: 2022

Journal Articles

Clonal Myeloid Heterogeneity in Older Autopsy Patients Determined By Multiple Bone Marrow Site Sequencing

Rohan Kodgule, Joshua Robinson, Sridhar Nonavinkere Srivatsan, Cara Lunn Shirai, Feiyu Du, Tianjiao Wang, Ajay Khanna, Catrina Fronick, Robert Fulton, David H Spencer, Matthew J Walter, Eric Duncavage

Blood (2022) 140 (Supplement 1): 2874–2875.

https://doi.org/10.1182/blood-2022-162624

Published: 2022

Journal Articles

Therapeutic Targeting of Spliceosome Mutant Myeloid Neoplasms Via PARP1 Inhibition

Sayantani Sinha, Zhiyan Silvia Liu, Maxwell Bannister, Erica Arriaga-Gomez, Axia Song, Dawei Zong, Martina Sarchi, Elizabeth Bonner, Victor Corral, Cassandra Leibson, Wannasiri Chiraphapphaiboon, Derek Stirewalt, Joachim Deeg, Sumit Rai, Matthew J Walter, Timothy A. Graubert, Sergei Doulatov, Dang Hai Nguyen, Stanley Chun-Wei Lee

Blood (2022) 140 (Supplement 1): 217–219.

https://doi.org/10.1182/blood-2022-170574

Published: 2022

Journal Articles

IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function

Sidan Li, Juo-Chin Yao, Karolyn A. Oetjen, Joseph R. Krambs, Jun Xia, Jingzhu Zhang, Amy P. Schmidt, Nichole M. Helton, Robert S. Fulton, Sharon E. Heath, Isaiah R. Turnbull, Gabriel Mbalaviele, Timothy J. Ley, Matthew J. Walter, Daniel C. Link

Blood (2022) 140 (14): 1607–1620.

https://doi.org/10.1182/blood.2022016084

Published: 2022

Includes: Supplemental data

Journal Articles

Proteomic and phosphoproteomic landscapes of acute myeloid leukemia

Michael H. Kramer, Qiang Zhang, Robert Sprung, Ryan B. Day, Petra Erdmann-Gilmore, Yang Li, Ziheng Xu, Nichole M. Helton, Daniel R. George, Yiling Mi, Peter Westervelt, Jacqueline E. Payton, Sai M. Ramakrishnan, Christopher A. Miller, Daniel C. Link, John F. DiPersio, Matthew J. Walter, R. Reid Townsend, Timothy J. Ley

Blood (2022) 140 (13): 1533–1548.

https://doi.org/10.1182/blood.2022016033

Published: 2022

Includes: Supplemental data

Journal Articles

Meagan A. Jacoby, David A. Sallman, Bart L. Scott, Megan Haney, Fei Wan, John F. DiPersio, Ramzi Abboud, Keith E. Stockerl-Goldstein, Rami S. Komrokji, Mark A. Schroeder, Matthew J. Walter, Peter Westervelt, Geoffrey L. Uy

Blood (2021) 138 (Supplement 1): 540.

https://doi.org/10.1182/blood-2021-151137

Published: 2021

Journal Articles

Analysis of the Proteomes of Primary, De Novo Acute Myeloid Leukemia Cells from Adults

Michael H Kramer, Qiang Zhang, Robert W. Sprung, Petra Erdmann-Gilmore, Daniel R George, Nichole M Helton, Sharon E Heath, Jacqueline E. Payton, Peter Westervelt, Christopher A Miller, Matthew J. Walter, Daniel C. Link, John F. DiPersio, R Reid Townsend, Timothy J Ley

Blood (2021) 138 (Supplement 1): 3427.

https://doi.org/10.1182/blood-2021-148819

Published: 2021

Journal Articles

Inhibition of ATR with AZD6738 (Ceralasertib) for the Treatment of Progressive or Relapsed Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: Safety and Preliminary Activity from a Phase Ib/II Study

Andrew M. Brunner, Yiwen Liu, Lourdes M. Mendez, Jacqueline S. Garcia, Philip C. Amrein, Donna S. Neuberg, Emma Dean, Simon Smith, Richard M. Stone, Amir T. Fathi, Matthew J. Walter, Timothy A. Graubert, Meagan A. Jacoby

Blood (2021) 138 (Supplement 1): 1521.

https://doi.org/10.1182/blood-2021-147301

Published: 2021

Journal Articles

Adverse Outcomes in Acute Myeloid Leukemia Are Associated with Tumor Cell-Mediated Immunosuppression

Blood (2021) 138 (Supplement 1): 800.

https://doi.org/10.1182/blood-2021-148645

Published: 2021

Journal Articles

Mutant TRP53-R172H Has Gain-of-Function or Dominant-Negative Effects in Response to Different Hematopoietic Stressors in Mice

Tanzir Ahmed, PhD, Tuoen Liu, MD PhD, Michael O. Alberti, MDPhD, Brian Wadugu, PhD, Matthew Ndonwi, PhD, Sarah Grieb, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-141091

Published: 2020

Journal Articles

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Andrew J Menssen, BA, Ajay Khanna, Christopher A Miller, PhD, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Michelle O'Laughlin, Catrina Fronick, BS, Robert Fulton, MS, Kimberly J Brendel, Sharon E Heath, Peter Westervelt, MDPhD, John F. DiPersio, MD PhD, Daniel C. Link, MD, Meagan A. Jacoby, Eric Duncavage, MD, Timothy J Ley, MD, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-140394

Published: 2020

NARROW

Genetic Determinants of Clonal Hematopoiesis and Progression to Hematologic Malignancies in 479,117 Individuals

Reduced Subclone Diversity in Clonal Cytopenia of Undetermined Significance Compared to Myelodysplastic Syndrome

Primary U2AF1 S34F Mutated Hematopoietic Cells Are Sensitive to Nonsense-Mediated RNA Decay Disruption In Vivo

Plasma Proteomic Signature Predicts Risk of Myeloid Neoplasm

Correlation between Peripheral Blood and Bone Marrow Somatic Mutations Among Patients with Suspected or Established Myelodysplastic Syndromes from the National MDS Study

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia

Nonsense-Mediated RNA Decay Disruption Induces Altered Splicing in Spliceosome Mutant Cells

Spatial Organization of Hematopoietic Clones in the Bone Marrow of a Patient with Polycythemia Vera

Phase I Study of Baricitinib Gvhd Prophylaxis in HLA-Matched, Peripheral Blood Allogeneic Hematopoietic Cell Transplant

Dynamics of Mortality and Transformation Risk within Different Risk Groups of Patients with Myelodysplastic Syndromes Stratified According to the IPSS-R - Comparison of Treated and Untreated Patients and Consequences for the Description of Risk Categories

Clonal Myeloid Heterogeneity in Older Autopsy Patients Determined By Multiple Bone Marrow Site Sequencing

Therapeutic Targeting of Spliceosome Mutant Myeloid Neoplasms Via PARP1 Inhibition

IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function

Proteomic and phosphoproteomic landscapes of acute myeloid leukemia

A Pilot Study of CPX-351 (Vyxeos © ) for Transplant Eligible, Higher Risk Patients with Myelodysplastic Syndrome

Analysis of the Proteomes of Primary, De Novo Acute Myeloid Leukemia Cells from Adults

Inhibition of ATR with AZD6738 (Ceralasertib) for the Treatment of Progressive or Relapsed Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: Safety and Preliminary Activity from a Phase Ib/II Study

Adverse Outcomes in Acute Myeloid Leukemia Are Associated with Tumor Cell-Mediated Immunosuppression

Mutant TRP53-R172H Has Gain-of-Function or Dominant-Negative Effects in Response to Different Hematopoietic Stressors in Mice

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

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American Society of Hematology

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