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Matthew J. Walter
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Journal Articles

Clearance of Leukemia Associated Mutations (LAMs) after Induction Therapy Is Associated with Favorable Outcomes in Intermediate Risk Acute Myeloid Leukemia: Interim Results of a Multicenter, Prospective Phase II Trial

Meagan Jacoby, David H Spencer, Geoffrey L. Uy, Feng Gao, Tasha Burton, Sharon E Heath, Feiyu Du, Shelly O'Laughlin, Robert Fulton, Zeina A. Al-Mansour, Christopher R. Cogle, Eric J Huselton, John F. DiPersio, Peter Westervelt, Mark A. Schroeder, Armin Ghobadi, Iskra Pusic, Keith Stockerl-Goldstein, Brad S. Kahl, Amanda F. Cashen, Matt Christopher, Nathan Singh, Ravi Vij, Zachary D. Crees, Ryan B. Day, Todd A Fehniger, Karolyn Oetjen, Dilan A. Patel, Miriam Y Kim, Michael Slade, Daniel C. Link, Matthew J. Walter, Camille N. Abboud, Ramzi Abboud, Timothy J Ley
Journal: Blood
Blood (2024) 144 (Supplement 1): 224.
https://doi.org/10.1182/blood-2024-201694
Published: 2024
Journal Articles

Association between Smoking Intensity, Genetic Mutations, and Disease Progression in Myelodysplastic Syndromes

Sangeetha Venugopal, Michael Otterstatter, Amy E. DeZern, Matthew J. Walter, James M. Foran, Rafael Bejar, Tareq Al Baghdadi, H. Joachim Deeg, Rami S. Komrokji, Gregory A Abel, R. Coleman Lindsley, Jane Jijun Liu, Yazan F Madanat, Lynn C. Moscinski, Wael Saber, Jennifer Vidrine, Damon J. Vidrine, Ling Zhang, Christine Borchert, Seth Sherman, Nancy DiFronzo, Nancy Gillis, Mikkael A. Sekeres
Journal: Blood
Blood (2024) 144 (Supplement 1): 4597.
https://doi.org/10.1182/blood-2024-206034
Published: 2024
Journal Articles

Progression of Myelodysplastic Syndromes in the MDS Natural History Study (MDS NHS)

Amy E. DeZern, Michael Otterstatter, Nancy Gillis, Gregory A Abel, Tareq Al Baghdadi, Rafael Bejar, H. Joachim Deeg, James M. Foran, Rami S. Komrokji, R. Coleman Lindsley, Jane Jijun Liu, Lynn C. Moscinski, Wael Saber, Ling Zhang, Christine Borchert, Eric Padron, Seth Sherman, Nancy DiFronzo, Matthew J. Walter, Mikkael A. Sekeres
Journal: Blood
Blood (2024) 144 (Supplement 1): 1831.
https://doi.org/10.1182/blood-2024-201613
Published: 2024
Journal Articles

Clinical Activity and Safety of the Oral ATR Inhibitor Ceralasertib (AZD6738) in Patients with MDS or CMML after Prior HMA Therapy

Andrew M. Brunner, Yiwen Liu, Jacqueline S. Garcia, Lourdes Mendez, Catherine Gutierrez, Philip C. Amrein, Rupa Narayan, Rahul Vedula, Donna S. Neuberg, Marcio Andrade-Campos, Simon Smith, Richard M Stone, Amir T. Fathi, Matthew J. Walter, Timothy Aaron Graubert, Meagan Jacoby
Journal: Blood
Blood (2024) 144 (Supplement 1): 1833.
https://doi.org/10.1182/blood-2024-195793
Published: 2024
Journal Articles

Robust Copy Number Alteration Detection (RCNA): A Novel Algorithm for Detecting Copy-Number Alterations for Targeted Gene Sequencing Experiments

Travis L Jensen, Matthew D Bradley, Ling Zhang, Rafael Bejar, R. Coleman Lindsley, Matthew J. Walter, Johannes Goll
Journal: Blood
Blood (2024) 144 (Supplement 1): 3220.
https://doi.org/10.1182/blood-2024-210552
Published: 2024
Journal Articles

Genetic Determinants of Clonal Hematopoiesis and Progression to Hematologic Malignancies in 479,117 Individuals

Jie Liu, Duc Tran, Irenaeus C.C. Chan, Brian Wiley, Caroline Watson, Armel L. Batchi-Bouyou, Xiaoyu Zong, Konrad H. Stopsack, Paul Pharoah, Li Ding, Jamie R Blundell, Yin Cao, Matthew J. Walter, Nilanjan Chatterjee, Kenneth Offit, Lucy Godley, Daniel C. Link, Zsofia Stadler, Kelly L. Bolton
Journal: Blood
Blood (2023) 142 (Supplement 1): 811.
https://doi.org/10.1182/blood-2023-182423
Published: 2023
Journal Articles

Primary U2AF1 S34F Mutated Hematopoietic Cells Are Sensitive to Nonsense-Mediated RNA Decay Disruption In Vivo

Claudia Cabrera, Sridhar N Srivatsan, Abigael Cheruiyot, Tanzir Ahmed, Zheng Yang, Jin Shao, Monique Chavez, Sarah Grieb, Julie Bailis, Zhongsheng You, Matthew J. Walter
Journal: Blood
Blood (2023) 142 (Supplement 1): 43.
https://doi.org/10.1182/blood-2023-181984
Published: 2023
Journal Articles

Plasma Proteomic Signature Predicts Risk of Myeloid Neoplasm

J. Scott Beeler, Duc Tran, Jie Liu, Zilan Xin, Brian Wiley, Irenaeus C.C. Chan, Michael H. Kramer, Armel L. Batchi-Bouyou, Xiaoyu Zong, Matthew J. Walter, Sarantis Chlamydas, Francesca Ferraro, Stephen T. Oh, Ben Busby, Daniel C. Link, Yin Cao, Kelly L. Bolton
Journal: Blood
Blood (2023) 142 (Supplement 1): 940.
https://doi.org/10.1182/blood-2023-190857
Published: 2023
Journal Articles

Reduced Subclone Diversity in Clonal Cytopenia of Undetermined Significance Compared to Myelodysplastic Syndrome

Monique Chavez, Sridhar N Srivatsan, Christopher A Miller, Andrew J. Menssen, Ajay Khanna, Jin Shao, Catrina Fronick, Robert Fulton, Sharon E Heath, Constantine Logothetis, Tasha Burton, Victoria Donaldson, Claudia Cabrera, Raya Saba, Kiran R. Vij, Eric J. Duncavage, Meagan Jacoby, Matthew J. Walter
Journal: Blood
Blood (2023) 142 (Supplement 1): 2696.
https://doi.org/10.1182/blood-2023-189591
Published: 2023
Journal Articles

Correlation between Peripheral Blood and Bone Marrow Somatic Mutations Among Patients with Suspected or Established Myelodysplastic Syndromes from the National MDS Study

Amy E. DeZern, Johannes Goll, Travis L Jensen, Sridhar N Srivatsan, Nancy K Gillis, Gregory A Abel, Eric Padron, H. Joachim Deeg, Tareq Al Baghdadi, Jane Lijun Liu, Rami S. Komrokji, Steven D. Gore, Wael Saber, Rafael Bejar, Matthew J. Walter, Seth Sherman, Nancy DiFronzo, Mikkael A. Sekeres
Journal: Blood
Blood (2023) 142 (Supplement 1): 1860.
https://doi.org/10.1182/blood-2023-178587
Published: 2023
Journal Articles

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia

Clinical Trials & Observations
Eric J. Duncavage, Adam Bagg, Robert P. Hasserjian, Courtney D. DiNardo, Lucy A. Godley, Ilaria Iacobucci, Siddhartha Jaiswal, Luca Malcovati, Alessandro M. Vannucchi, Keyur P. Patel, Daniel A. Arber, Maria E. Arcila, Rafael Bejar, Nancy Berliner, Michael J. Borowitz, Susan Branford, Anna L. Brown, Catherine A. Cargo, Hartmut Döhner, Brunangelo Falini, Guillermo Garcia-Manero, Torsten Haferlach, Eva Hellström-Lindberg, Annette S. Kim, Jeffery M. Klco, Rami Komrokji, Mignon Lee-Cheun Loh, Sanam Loghavi, Charles G. Mullighan, Seishi Ogawa, Attilio Orazi, Elli Papaemmanuil, Andreas Reiter, David M. Ross, Michael Savona, Akiko Shimamura, Radek C. Skoda, Francesc Solé, Richard M. Stone, Ayalew Tefferi, Matthew J. Walter, David Wu, Benjamin L. Ebert, Mario Cazzola
Journal: Blood
Blood (2022) 140 (21): 2228–2247.
https://doi.org/10.1182/blood.2022015853
Published: 2022
Includes: Supplemental data
Journal Articles

Phase I Study of Baricitinib Gvhd Prophylaxis in HLA-Matched, Peripheral Blood Allogeneic Hematopoietic Cell Transplant

Mark A. Schroeder, Jaebok Choi, Himachandana Atluri, Jordan Atkins, Melinda Harding, Jeremy Eisele, Feng Gao, Ramzi Abboud, Camille Abboud, Sr., Amanda F. Cashen, Matthew Christopher, Todd A. Fehniger, Francesca Ferraro, Armin Ghobadi, Meagan A. Jacoby, Iskra Pusic, Keith E Stockerl-Goldstein, Geoffrey L. Uy, Ravi Vij, Matthew J Walter, Peter Westervelt, John F. DiPersio
Journal: Blood
Blood (2022) 140 (Supplement 1): 1875–1876.
https://doi.org/10.1182/blood-2022-157214
Published: 2022
Journal Articles

Spatial Organization of Hematopoietic Clones in the Bone Marrow of a Patient with Polycythemia Vera

Andrew L Young, Hannah C Davis, David H Spencer, Timothy J Ley, Stephen T Oh, Matthew J Walter, Grant A Challen
Journal: Blood
Blood (2022) 140 (Supplement 1): 2910–2911.
https://doi.org/10.1182/blood-2022-167351
Published: 2022
Journal Articles

Therapeutic Targeting of Spliceosome Mutant Myeloid Neoplasms Via PARP1 Inhibition

Sayantani Sinha, Zhiyan Silvia Liu, Maxwell Bannister, Erica Arriaga-Gomez, Axia Song, Dawei Zong, Martina Sarchi, Elizabeth Bonner, Victor Corral, Cassandra Leibson, Wannasiri Chiraphapphaiboon, Derek Stirewalt, Joachim Deeg, Sumit Rai, Matthew J Walter, Timothy A. Graubert, Sergei Doulatov, Dang Hai Nguyen, Stanley Chun-Wei Lee
Journal: Blood
Blood (2022) 140 (Supplement 1): 217–219.
https://doi.org/10.1182/blood-2022-170574
Published: 2022
Journal Articles

Clonal Myeloid Heterogeneity in Older Autopsy Patients Determined By Multiple Bone Marrow Site Sequencing

Rohan Kodgule, Joshua Robinson, Sridhar Nonavinkere Srivatsan, Cara Lunn Shirai, Feiyu Du, Tianjiao Wang, Ajay Khanna, Catrina Fronick, Robert Fulton, David H Spencer, Matthew J Walter, Eric Duncavage
Journal: Blood
Blood (2022) 140 (Supplement 1): 2874–2875.
https://doi.org/10.1182/blood-2022-162624
Published: 2022
Journal Articles

Dynamics of Mortality and Transformation Risk within Different Risk Groups of Patients with Myelodysplastic Syndromes Stratified According to the IPSS-R - Comparison of Treated and Untreated Patients and Consequences for the Description of Risk Categories

Michael Pfeilstocker, Heinz Tuechler, Lionel Ades, Jaroslav Cermak, Fatiha Chermat, Matteo G. Della Porta, Pierre Fenaux, Guillermo Garcia-Manero, Ulrich Germing, Detlef Haase, Andrea Kuendgen, Michael Luebbert, Silvia Maria Meira Magalhaes, Luca Malcovati, Yasushi Miyazaki, Guillermo Sanz, Valeria Santini, Mikkael A. Sekeres, Matthew J Walter, Peter Valent, Peter L Greenberg
Journal: Blood
Blood (2022) 140 (Supplement 1): 6976–6978.
https://doi.org/10.1182/blood-2022-158671
Published: 2022
Journal Articles

Nonsense-Mediated RNA Decay Disruption Induces Altered Splicing in Spliceosome Mutant Cells

Claudia Cabrera, Sridhar Nonavinkere Srivatsan, Abigael Cheruiyot, Tanzir Ahmed, Zheng Yang, Jin J Shao, Monique Chavez, Julie Bailis, Zhongsheng You, Matthew J Walter
Journal: Blood
Blood (2022) 140 (Supplement 1): 6907–6908.
https://doi.org/10.1182/blood-2022-160373
Published: 2022
Journal Articles

IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function

Sidan Li, Juo-Chin Yao, Karolyn A. Oetjen, Joseph R. Krambs, Jun Xia, Jingzhu Zhang, Amy P. Schmidt, Nichole M. Helton, Robert S. Fulton, Sharon E. Heath, Isaiah R. Turnbull, Gabriel Mbalaviele, Timothy J. Ley, Matthew J. Walter, Daniel C. Link
Journal: Blood
Blood (2022) 140 (14): 1607–1620.
https://doi.org/10.1182/blood.2022016084
Published: 2022
Includes: Supplemental data
Journal Articles

Proteomic and phosphoproteomic landscapes of acute myeloid leukemia

Michael H. Kramer, Qiang Zhang, Robert Sprung, Ryan B. Day, Petra Erdmann-Gilmore, Yang Li, Ziheng Xu, Nichole M. Helton, Daniel R. George, Yiling Mi, Peter Westervelt, Jacqueline E. Payton, Sai M. Ramakrishnan, Christopher A. Miller, Daniel C. Link, John F. DiPersio, Matthew J. Walter, R. Reid Townsend, Timothy J. Ley
Journal: Blood
Blood (2022) 140 (13): 1533–1548.
https://doi.org/10.1182/blood.2022016033
Published: 2022
Includes: Supplemental data
Journal Articles

A Pilot Study of CPX-351 (Vyxeos © ) for Transplant Eligible, Higher Risk Patients with Myelodysplastic Syndrome

Meagan A. Jacoby, David A. Sallman, Bart L. Scott, Megan Haney, Fei Wan, John F. DiPersio, Ramzi Abboud, Keith E. Stockerl-Goldstein, Rami S. Komrokji, Mark A. Schroeder, Matthew J. Walter, Peter Westervelt, Geoffrey L. Uy
Journal: Blood
Blood (2021) 138 (Supplement 1): 540.
https://doi.org/10.1182/blood-2021-151137
Published: 2021