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Journal Articles

Increased Inflammatory Cytokines in Plasma Are Associated with Sustained Treatment-Free Remission in Chronic Myeloid Leukaemia

Chung Hoow Kok, Verity A Saunders, Naranie Shanmuganathan, Liu Liu, Yazad Daruis Irani, Jade Clarson, Phuong Dang, David T Yeung, Agnes S. M. Yong, Susan Branford, Javier Pinilla-Ibarz, Richard A. Larson, Jorge E. Cortes, Michael J. Mauro, James E Thompson, Neil P. Shah, Martha Wadleigh, Ehab L. Atallah, Jerald P. Radich, Timothy P Hughes, David M Ross
Journal: Blood
Blood (2024) 144 (Supplement 1): 993.
https://doi.org/10.1182/blood-2024-201881
Published: 2024
Journal Articles

The Prognostic and Predictive Value of RUNX1 Mutations in Newly Diagnosed Acute Myeloid Leukemia - an International Multicenter Cohort Study

Rebecca P. Bystrom, Jan Philipp Bewersdorf, Yiwen Liu, Eva Johanna Schaefer, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Sylvain Garciaz, Luis E. Aguirre, Daniel J. DeAngelo, Richard M. Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan C. Chen, Martha Wadleigh, Kelly Ling, Eytan M. Stein, Aaron D. Goldberg, Amer M. Zeidan, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 2947.
https://doi.org/10.1182/blood-2024-205581
Published: 2024
Journal Articles

Comparative Analysis of Outcomes with HMA Plus Venetoclax Vs Intensive Chemotherapy in AML Patients Harboring Very-High Risk Cytogenetics

Luis E. Aguirre, Jan Philipp Bewersdorf, Yiwen Liu, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Sylvain Garciaz, Rebecca P. Bystrom, Daniel J. DeAngelo, Richard M. Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Kelly Ling, Evan C. Chen, Martha Wadleigh, Eytan M. Stein, Aaron D. Goldberg, Amer M. Zeidan, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4267.
https://doi.org/10.1182/blood-2024-202744
Published: 2024
Journal Articles

Venetoclax-Based Therapy Versus Intensive Chemotherapy Followed By Allogeneic-Stem Cell Transplantation for High-Risk Elderly Acute Myeloid Leukemia

Alexandre Iat, Jan Philipp Bewersdorf, Julia Gilhodes, Yiwen Liu, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Rebecca P. Bystrom, Daniel J. DeAngelo, Guillaume Berton, Amel Soua, Kelly Ling, Luis E. Aguirre, Richard M Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan C. Chen, Martha Wadleigh, Aaron D. Goldberg, Amer M. Zeidan, Thomas Cluzeau, Shai O. Shimony, Maximilian Stahl, Sylvain Garciaz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1508.
https://doi.org/10.1182/blood-2024-207045
Published: 2024
Journal Articles

Final Analysis of a Phase I Study of Escalating Doses of the BCL-2 Inhibitor Venetoclax in Combination with Daunorubcin/Cytarabine Induction and High Dose Cytarabine Consolidation in Previously Untreated Adults with Acute Myeloid Leukemia

Richard M Stone, Daniel J. DeAngelo, Anthony G. Letai, Ilene A. Galinsky, Howard Weiner, Austen Halpin, Lexi Noyes, Hunter Smith, Carter Lombardi, Rebecca Leonard, Geoffrey Fell, Yael Flammand, Jeremy Ryan, Marina Konopleva, Martha Wadleigh, Maximilian Stahl, Evan Chen, Virginia O. Volpe, Eric S. Winer, Jacqueline S. Garcia, Marlise R. Luskin, Anand Ashwin Patel
Journal: Blood
Blood (2024) 144 (Supplement 1): 4261.
https://doi.org/10.1182/blood-2024-203683
Published: 2024
Journal Articles

Outcomes with HMA Plus Venetoclax Vs Intensive Chemotherapy in AML Patients with Chromosome 5 and 7 Abnormalities

Leora Boussi, Jan Philipp Bewersdorf, Yiwen Liu, Rory M. Shallis, Luis E. Aguirre, Andrius Zucenka, Sylvain Garciaz, Rebecca P. Bystrom, Daniel J. DeAngelo, Richard M Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan Chen, Martha Wadleigh, Kelly Ling, Amer M. Zeidan, Aaron D. Goldberg, Eytan M. Stein, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4281.
https://doi.org/10.1182/blood-2024-204467
Published: 2024
Journal Articles

Redefining Clinical Response Criteria in Myelodysplastic Syndromes to Better Forecast Post-Transplant Outcomes

Luis E. Aguirre, Haesook T. Kim, Hany Elmariah, Stacey M. Frumm, Amar H. Kelkar, Vincent T. Ho, Mahasweta Gooptu, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai O. Shimony, Marlise R. Luskin, Jacqueline S. Garcia, Kelly Ling, Evan C. Chen, Martha Wadleigh, Eric S. Winer, Richard M. Stone, Daniel J. DeAngelo, Najla H. Al Ali, Corey S. Cutler, Rami S. Komrokji, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4938.
https://doi.org/10.1182/blood-2024-209087
Published: 2024
Journal Articles

Asciminib plus dasatinib and prednisone for Philadelphia chromosome-positive acute leukemia

Clinical Trials & Observations
Marlise R. Luskin, Mark Alan Murakami, Julia H. Keating, Yael Flamand, Eric S Winer, Jacqueline S. Garcia, Maximilian Stahl, Richard M. Stone, Martha Wadleigh, Stella Louise Jaeckle, Ella Hagopian, David M. Weinstock, Jessica Liegel, Malgorzata McMasters, Eunice S Wang, Wendy Stock, Daniel J DeAngelo
Journal: Blood
Blood blood.2024025800.
https://doi.org/10.1182/blood.2024025800
Published: 2024
Includes: Supplemental data
Journal Articles

A Phase 2 Study of Lenalidomide in Combination with Mitoxantrone, Etoposide, and Cytarabine (Len plus MEC) in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Manik Razdan Kuchroo, Robert A. Redd, Jacqueline S. Garcia, Michael Keng, Gabriela S. Hobbs, Jacalyn Rosenblatt, Marlise R. Luskin, Rupa Narayan, Philip C. Amrein, Malgorzata McMasters, Martha Wadleigh, Hanno Hock, Richard Stone, Donna S. Neuberg, David Avigan, Karen K. Ballen, Amir T. Fathi, Daniel J. DeAngelo, Andrew M. Brunner
Journal: Blood
Blood (2023) 142 (Supplement 1): 2894.
https://doi.org/10.1182/blood-2023-188182
Published: 2023
Journal Articles

Impact of Clinical and Genetic Factors on Myelofibrosis Outcomes after Allogeneic Transplantation

Mahasweta Gooptu, Haesook T. Kim, Kaina Chen, Ann Mullally, Joseph Antin, Corey Cutler, Amar H Kelkar, John Koreth, Roman M. Shapiro, Robert J. Soiffer, Daniel J. DeAngelo, Jacqueline S. Garcia, Marlise R. Luskin, Richard M Stone, Martha Wadleigh, Eric S. Winer, R. Coleman Lindsley, Vincent Ho
Journal: Blood
Blood (2023) 142 (Supplement 1): 4978.
https://doi.org/10.1182/blood-2023-178684
Published: 2023
Journal Articles

Phase 1 Study of BXCL701, a Dipeptidyl Peptidase Inhibitor, in Relapsed/Refractory Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome

Eric S. Winer, Jacqueline S. Garcia, Richard M Stone, Martha Wadleigh, Marlise R. Luskin, Maximilian Stahl, Evan C. Chen, Rebecca Leonard, Alexis Noyes, Ilene Galinsky, Rashmi Deshpande, Pascal Borderies, Vincent O'Neill, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 1549.
https://doi.org/10.1182/blood-2023-186598
Published: 2023
Journal Articles

A Simple Prediction Model of Outcomes after Allogeneic Hematopoietic Stem Cell Transplant (HCT) in Myelodysplastic Syndromes Using HCT-Comorbidity Index, Cytogenetic Risk, and Platelet Count

Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 2246.
https://doi.org/10.1182/blood-2023-185315
Published: 2023
Journal Articles

Updated Results on a Multicenter Phase II Study of a Dose Intensified Pediatric Regimen in Adults with Acute Lymphoblastic Leukemia: The 06-254 DFCI ALL Consortium Trial

Yannis K. Valtis, Yael Flamand, Shai Shimony, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Martha Wadleigh, Jacqueline S. Garcia, Eric S. Winer, Ilene Galinsky, Julie Bergeron, Julie Asch, Matthew D. Seftel, Richard M Stone, Marlise R. Luskin, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4238.
https://doi.org/10.1182/blood-2023-181014
Published: 2023
Journal Articles

Subunit-Specific Analysis of Cohesin-Mutant Myeloid Malignancies Reveals Distinct Ontogeny and Outcomes

Johann-Christoph Jann, Christopher B. Hergott, Marisa Winkler, Yiwen Liu, Benjamin Braun, Anne Charles, Kevin Copson, Shougat Barua, Manja Meggendorfer, Niroshan Nadarajah, Shai Shimony, Eric S. Winer, Martha Wadleigh, Richard M Stone, Daniel J. DeAngelo, Jacqueline S. Garcia, Torsten Haferlach, Coleman Lindsley, Marlise R. Luskin, Maximilian Stahl, Zuzana Tothova
Journal: Blood
Blood (2023) 142 (Supplement 1): 999.
https://doi.org/10.1182/blood-2023-187519
Published: 2023
Journal Articles

A Phase I Study of Asciminib (ABL001) in Combination with Dasatinib and Prednisone for BCR-ABL1-Positive ALL and Blast Phase CML in Adults

Marlise R. Luskin, Mark Alan Murakami, Julia Keating, Eric S. Winer, Jacqueline S. Garcia, Maximilian Stahl, Martha Wadleigh, Yael Flamand, Donna S. Neuberg, Ilene Galinsky, Rebecca Leonard, Ella Hagopian, Chase M Weizer, Carlin McLanahan, Richard M Stone, Eunice S. Wang, Wendy Stock, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 965.
https://doi.org/10.1182/blood-2023-174246
Published: 2023
Journal Articles

Post Allogeneic Stem Cell Transplant Outcomes Following Response to Hypomethylating Agent Therapy in Myelodysplastic Syndromes Are Predicted By Persistent International Prognostic Scoring System-Molecular Risk

Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 3618.
https://doi.org/10.1182/blood-2023-185220
Published: 2023
Journal Articles

Tagraxofusp in Combination with Azacitidine and Venetoclax in Newly Diagnosed CD123+ Acute Myeloid Leukemia, Expansion Cohort of a Phase 1b Multicenter Trial

Andrew A. Lane, Jacqueline S. Garcia, Evangeline G. Raulston, Jada L. Garzon, Ilene Galinsky, Emilie W. Baxter, Rebecca Leonard, Daniel J. DeAngelo, Marlise R. Luskin, Christopher R. Reilly, Maximilian Stahl, Richard M Stone, Rahul Vedula, Martha Wadleigh, Eric S. Winer, Tariq Mughal, Christopher Brooks, Ira V. Gupta, Kristen E. Stevenson, Donna S. Neuberg, Siyang Ren, Marina Y. Konopleva, Anthony Stein, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 4277.
https://doi.org/10.1182/blood-2023-180010
Published: 2023
Journal Articles

Venous Thromboembolism in Adolescents and Young Adults with Acute Lymphoblastic Leukemia Treated on a Pediatric-Inspired Regimen

Hari S. Raman, Shai Shimony, Yannis K. Valtis, Yael Flamand, Andrew E. Place, Lewis B. Silverman, Stephen E. Sallan, Lynda M. Vrooman, Andrew M. Brunner, Donna S. Neuberg, Ilene Galinsky, Jacqueline S. Garcia, Eric S. Winer, Martha Wadleigh, Richard M Stone, Jean M. Connors, Daniel J. DeAngelo, Marlise R. Luskin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1456.
https://doi.org/10.1182/blood-2023-178353
Published: 2023
Journal Articles

Ipilimumab plus decitabine for patients with MDS or AML in posttransplant or transplant-naïve settings

Clinical Trials & Observations
Jacqueline S. Garcia, Yael Flamand, Livius Penter, Michael Keng, Benjamin K. Tomlinson, Lourdes M. Mendez, Paul Koller, Nicole Cullen, Yohei Arihara, Kathleen Pfaff, Jacquelyn O. Wolff, Andrew M. Brunner, Ilene Galinsky, Asad Bashey, Joseph H. Antin, Corey Cutler, Vincent Ho, Brian A. Jonas, Marlise R. Luskin, Martha Wadleigh, Eric S. Winer, Alexandra Savell, Rebecca Leonard, Taylor Robertson, Matthew S. Davids, Howard Streicher, Scott J. Rodig, Jerome Ritz, Catherine J. Wu, Daniel J. DeAngelo, Donna Neuberg, Richard M. Stone, Robert J. Soiffer
Journal: Blood
Blood (2023) 141 (15): 1884–1888.
https://doi.org/10.1182/blood.2022017686
Published: 2023
Includes: Supplemental data
Journal Articles

Body Mass Index Effect on Survival and Toxicities Differs between Age Groups Among Adolescents and Young Adults Treated on DFCI Consortium ALL Trials

Shai Shimony, Yael Flamand, Yannis K. Valtis, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Richard M. Stone, Martha Wadleigh, Donna S. Neuberg, Daniel J DeAngelo, Marlise R. Luskin
Journal: Blood
Blood (2022) 140 (Supplement 1): 3164–3165.
https://doi.org/10.1182/blood-2022-158348
Published: 2022