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Neil P. Shah
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Journal Articles

The promise of allosteric kinase inhibition

Clinical Trials & Observations
Neil P. Shah
Journal: Blood
Blood (2024) 144 (19): 1975–1976.
https://doi.org/10.1182/blood.2024026052
Published: 2024
Journal Articles

Increased Inflammatory Cytokines in Plasma Are Associated with Sustained Treatment-Free Remission in Chronic Myeloid Leukaemia

Chung Hoow Kok, Verity A Saunders, Naranie Shanmuganathan, Liu Liu, Yazad Daruis Irani, Jade Clarson, Phuong Dang, David T Yeung, Agnes S. M. Yong, Susan Branford, Javier Pinilla-Ibarz, Richard A. Larson, Jorge E. Cortes, Michael J. Mauro, James E Thompson, Neil P. Shah, Martha Wadleigh, Ehab L. Atallah, Jerald P. Radich, Timothy P Hughes, David M Ross
Journal: Blood
Blood (2024) 144 (Supplement 1): 993.
https://doi.org/10.1182/blood-2024-201881
Published: 2024
Journal Articles

Living with CML: A Qualitative Analysis

Kelly Schoenbeck, Isabelle Vu, Albert Lee, Mansa Devaki, Insiyah Merchant, Faaiz Ibrahim, Anand Dhruva, Catherine C. Smith, Neil P. Shah, Chloe Atreya
Journal: Blood
Blood (2024) 144 (Supplement 1): 5185.
https://doi.org/10.1182/blood-2024-212336
Published: 2024
Journal Articles

U.S. Expert Consensus on Defining Intolerance to Tyrosine Kinase Inhibitor Treatment in Chronic Phase Chronic Myeloid Leukemia (CML)

Ehab L. Atallah, Michael S. Broder, Onyee Chan, Hannah Dalglish, Kathryn E. Flynn, Jeffrey Gilreath, Marisa Hine, Anthony M. Hunter, Michael J. Mauro, Javier Pinilla-Ibarz, Lindsay A.M. Rein, Neil P. Shah, Evan Stemper, Srinivas K Tantravahi, Jay Yang
Journal: Blood
Blood (2024) 144 (Supplement 1): 5052.
https://doi.org/10.1182/blood-2024-194617
Published: 2024
Journal Articles

BCR :: ABL1 kinase N-lobe mutants confer moderate to high degrees of resistance to asciminib

Clinical Trials & Observations Brief Report
Ariel Leyte-Vidal, Diego Garrido Ruiz, RosaAnna DeFilippis, Inga B. Leske, Delphine Rea, Stacey Phan, Kaeli B. Miller, Feifei Hu, Anjeli Mase, Yibing Shan, Oliver Hantschel, Matthew P. Jacobson, Neil P. Shah
Journal: Blood
Blood (2024) 144 (6): 639–645.
https://doi.org/10.1182/blood.2023022538
Published: 2024
Journal Articles

HJKC3-007: Outcomes of Patients with Chronic Myeloid Leukemia in Chronic Phase Treated with Asciminib and Other Tyrosine Kinase Inhibitors in Routine Clinical Practice

Michael Mauro, Ehab L. Atallah, James E Thompson, Yan Gao, Alexis Visotcky, Emily Giever, Arielle Baim, Idayat Akinola, Richard A. Larson, Omer Jamy, Jorge Cortes, Brian J. Druker, Neil P. Shah, Javier Pinilla-Ibarz, Jay Yang, Ellen K. Ritchie, Lindsay A.M Rein, Srinivas K. Tantravahi, Talha Badar, B. Douglas Smith, Michael W. Deininger, Kathryn E Flynn
Journal: Blood
Blood (2023) 142 (Supplement 1): 7434.
https://doi.org/10.1182/blood-2023-188683
Published: 2023
Journal Articles

Outcomes of Adolescents and Young Adult Patients with Chronic Myeloid Leukemia in the Era of Second-Generation TKIs and Treatment-Free Remission

Kelly Schoenbeck, Anousheh Afjei, Neil P. Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 3173.
https://doi.org/10.1182/blood-2023-188395
Published: 2023
Journal Articles

BGS-2456 Is a Novel Potent Covalent Inhibitor of FLT3 That Highly Discriminates Against KIT and Is Not Toxic Toward Normal Hematopoiesis in Vitro

Ariel Leyte-Vidal, Stacey Phan, Prachi Khare, FeiFei Hu, Chao Zhang, Ping Cao, Neil P. Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 2265.
https://doi.org/10.1182/blood-2023-173116
Published: 2023
Journal Articles

HJKC3-0006: Outcome of Patients with CML Treated on Second Line or Later Therapy in Routine Clinical Practice

James E Thompson, Yan Gao, Alexis Visotcky, Kathryn E Flynn, Michael Mauro, Emily Giever, Arielle Baim, Idayat Akinola, Richard Larson, Omer Jamy, Anthony M. Hunter, Vamsi K. Kota, Jorge Cortes, Brian J. Druker, Neil P. Shah, Javier Pinilla-Ibarz, Jay Yang, Ellen K. Ritchie, Lindsay A.M Rein, B. Douglas Smith, Srinivas K. Tantravahi, Talha Badar, Michael W. Deininger, Ehab L. Atallah
Journal: Blood
Blood (2023) 142 (Supplement 1): 7420.
https://doi.org/10.1182/blood-2023-179963
Published: 2023
Journal Articles

Select P-Loop Mutants in BCR::ABL1 Confer Moderate to High Degrees of Resistance to Asciminib

Ariel Monet Leyte-Vidal, Neil P. Shah
Journal: Blood
Blood (2022) 140 (Supplement 1): 9606–9607.
https://doi.org/10.1182/blood-2022-169828
Published: 2022
Journal Articles

Being Present-CML: A Distress Reduction Intervention for Patients with Chronic Myeloid Leukemia Taking Tyrosine Kinase Inhibitors

Kelly L. Schoenbeck, Anand Dhruva, Albert Lee, Neha G. Goyal, Adrienne K. Yang, Sa Ra Park, Catherine C. Smith, Neil P Shah, Chloe E. Atreya
Journal: Blood
Blood (2021) 138 (Supplement 1): 4051.
https://doi.org/10.1182/blood-2021-152076
Published: 2021
Journal Articles

Dose Modification Dynamics of Ponatinib in Patients with Chronic-Phase Chronic Myeloid Leukemia (CP-CML) from the PACE and Optic Trials

Elias J. Jabbour, Michael W. Deininger, Elisabetta Abruzzese, Jane F Apperley, Jorge E. Cortes, Charles Chuah, Daniel J. DeAngelo, John F. DiPersio, Andreas Hochhaus, Jeffrey H. Lipton, Franck E. Nicolini, Javier Pinilla Ibarz, Delphine Rea, Gianantonio Rosti, Philippe Rousselot, Michael J. Mauro, Neil P Shah, Moshe Talpaz, Alexander Vorog, Vickie Lu, Hagop Kantarjian
Journal: Blood
Blood (2021) 138 (Supplement 1): 2550.
https://doi.org/10.1182/blood-2021-146175
Published: 2021
Journal Articles

Cognitive Dysfunction Associated with Tyrosine Kinase Inhibitors in Patients with CML in Chronic Phase

Kelly L. Schoenbeck, MD, Sirisha Tummala, MD, Neha G. Goyal, PhD, Catherine C. Smith, MD, Neil P. Shah, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-142997
Published: 2020
Journal Articles

Excellent Outcomes Achieved with Medical Management of Chronic Phase CML Patients with Non-Hematologic TKI Intolerance

Kelly L. Schoenbeck, MD, Sirisha Tummala, MD, Rebecca L. Olin, MD, Neha G. Goyal, PhD, Anand Dhruva, MD, Lloyd E. Damon, MD, Aaron C. Logan, MDPhDMPhil, Catherine C. Smith, MD, Neil P. Shah, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-143303
Published: 2020
Journal Articles

Efficacy and Safety of Ponatinib (PON) in Patients with Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Who Failed One or More Second-Generation (2G) Tyrosine Kinase Inhibitors (TKIs): Analyses Based on PACE and Optic

Hagop M. Kantarjian, MD, Michael W. Deininger, MD PhD, Elisabetta Abruzzese, MD, Jane Apperley, FRCP, FRCPath, MB, Jorge E. Cortes, MD, Charles Chuah, MD, Daniel J. DeAngelo, MD PhD, John F. DiPersio, MD PhD, Andreas Hochhaus, MD, Jeffrey H. Lipton, MD PhD, Franck E Nicolini, MDPhD, Javier Pinilla Ibarz, MD PhD, Delphine Rea, MDPhD, Gianantonio Rosti, MD, Philippe Rousselot, MDPhD, Neil P Shah, MD PhD, Moshe Talpaz, MD, Shouryadeep Srivastava, MBBS, PhD, Vickie Lu, PhD, Michael J. Mauro, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43–44.
https://doi.org/10.1182/blood-2020-133922
Published: 2020
Journal Articles

Patient-Reported Outcome Results from the U.S. Life after Stopping TKIs (LAST) Study in Patients with Chronic Myeloid Leukemia

Kathryn E Flynn, PhD, Kevin P. Weinfurt, PhD, Li Lin, MS, Jerald P. Radich, MD, Charles A. Schiffer, MD, Michael J. Mauro, MD, Javier Pinilla Ibarz, MD PhD, Joseph O. Moore, MD, Richard A. Larson, MD, Vivian G. Oehler, MD, Michael W. Deininger, James E. Thompson, MD, Neil P Shah, MD PhD, Martha Wadleigh, MD, Ellen K. Ritchie, MD, Richard T. Silver, MD, Jorge E. Cortes, MD, Vamsi Kota, Ehab L. Atallah, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 705.
https://doi.org/10.1182/blood-2019-126002
Published: 2019
Journal Articles

Symptom Assessment in Patients with BCR-ABL-Negative Myeloproliferative Neoplasms at an Academic Medical Institution

Kelly L. Schoenbeck, MD, Miguel Carlos Cerejo, DO, Patricia A. Cornett, MD, Lloyd E. Damon, MD, Karin L. Gaensler, MD, Andrew D. Leavitt, MD, Aaron C. Logan, MD PhD, Gabriel N. Mannis, MD, Rebecca L. Olin, MD, Giselle Salmasi, MD, Peter H. Sayre, MD PhD, Neil P. Shah, MD PhD, Anand Dhruva, MD, Chloe E. Atreya, MD PhD, Catherine C. Smith, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5859.
https://doi.org/10.1182/blood-2019-129638
Published: 2019
Journal Articles

Cage Transcriptome Analysis Reveals BCL2A1 Upregulation in FLT3 -ITD/D835 Dual Mutated AML Cells Harboring Complex Co-Mutations

Kotoko Yamatani, MD, Tomohiko Ai, MD PhD, Kaori Saito, Haeun Yang, Koya Suzuki, PhD, Atsushi Hori, PhD, Yuko Murakami-Tonami, MD PhD, Weiguo Zhang, MD PhD, Bing Z Carter, PhD, Sonoko Kinjo, PhD, Kazuho Ikeo, PhD, Katayama Kazuhiro, Hironori Harada, MD PhD, Takashi Miida, MD PhD, Neil P. Shah, MD PhD, Marina Y Konopleva, MD PhD, Yoshihide Hayashizaki, MD PhD, Michael Andreeff, MD PhD, Yoko Tabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1264.
https://doi.org/10.1182/blood-2019-124685
Published: 2019
Journal Articles

Association of High Body Mass Index with Response Outcomes in Patients with CML-CP Treated with Dasatinib Versus Imatinib in the First Line: Exploratory Post Hoc Analysis of the Phase 3 DASISION Trial

Massimo Breccia, MD, Jorge E. Cortes, MD, Neil P Shah, MD PhD, Giuseppe Saglio, MD, Antonio Jiménez-Velasco, MD, Philipp Le Coutre, MD, Alexander Brun, PharmD, Irene DeGutis, Sai Bathena, Oumar Sy, PhD, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4155.
https://doi.org/10.1182/blood-2019-121872
Published: 2019
Journal Articles

Multiparameter Single Cell Analysis to Identify Immune Cell States That May Contribute to Successful Treatment Discontinuation in Patients with Chronic Myeloid Leukemia

Kibeom Jang, PhD, Neil P. Shah, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2999.
https://doi.org/10.1182/blood-2018-99-119267
Published: 2018