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Journal Articles

Azacytidine Sensitizes AML Cells for Effective Elimination By CD123 CAR T-Cells

Nadia El Khawanky, Bsc(Biomed), BHlthSc(Hons), Amy Hughes, PhD, Wenbo Yu, PhD, Sanaz Taromi, PhD, Jade Clarson, BSc, Angel F. Lopez, MD PhD, Michael P. Brown, MD PhD, Justus Duyster, MD, Timothy P. Hughes, MDMBBS,FRACP,FRCPA, Deborah L. White, PhD FFSc (RCPA), Agnes S. M. Yong, MD PhD, Robert Zeiser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3904.
https://doi.org/10.1182/blood-2019-124684
Published: 2019
Journal Articles

Nilotinib/Interferon-α Combination Rapidly Enhances Leukaemia-Associated Antigen-Specific Cytotoxic T-Lymphocyte Immune Responses, Limits Natural Killer Cell Maturation and Triggers B Cell Remodelling

Amy Hughes, PhD, Jade Clarson, Deborah L White, PhD FFSc (RCPA), David Yeung, PhDBSc,FRACP,FRCPA,MBBS, Timothy P. Hughes, MD MBBS, FRACP, FRCPA, Agnes S. M. Yong, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1581.
https://doi.org/10.1182/blood.V130.Suppl_1.1581.1581
Published: 2017
Journal Articles

CML patients with deep molecular responses to TKI have restored immune effectors and decreased PD-1 and immune suppressors

Amy Hughes, Jade Clarson, Carine Tang, Ljiljana Vidovic, Deborah L. White, Timothy P. Hughes, Agnes S. M. Yong
Journal: Blood
Blood (2017) 129 (9): 1166–1176.
https://doi.org/10.1182/blood-2016-10-745992
Published: 2017
Includes: Supplemental data
Journal Articles

Enhanced Natural Killer and Cytotoxic T Lymphocyte Responses, with Decreased Monocytic Myeloid Derived Suppressor Cells May Promote Treatment Free Remission in Chronic Myeloid Leukaemia Patients Following Tyrosine Kinase Inhibitor Cessation

Amy Hughes, PhD, Jade Clarson, B.Sc, Deborah L White, PhD FFSc (RCPA), David M. Ross, MBBS, PhD FRACP, FRCPA, Timothy P. Hughes, MD FRACP, FRCPA, MBBS, FAAHMS, Agnes S Yong, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1122.
https://doi.org/10.1182/blood.V128.22.1122.1122
Published: 2016
Journal Articles

Chronic Myeloid Leukemia Patients with Deep Molecular Responses to Tyrosine Kinase Inhibitors Have Increased Effector Natural Killer and Cytotoxic T Cell Immune Responses to Leukaemia-Associated Antigens and Concomitant Reduced Immune Suppressors

Amy Hughes, B.Sc (hons), PhD, Carine Tang, B.Sc (hons), PhD, Jade Clarson, B.Sc, Ljiljana Vidovic, Animal Sc (hons), Timothy P. Hughes, MD MBBS, FRACP, FRCPA, Agnes S Yong, MD PhD
Journal: Blood
Blood (2015) 126 (23): 18.
https://doi.org/10.1182/blood.V126.23.18.18
Published: 2015