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Yohei Arihara
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Journal Articles

Baseline immune state and T-cell clonal kinetics are associated with durable response to CAR-T therapy in large B-cell lymphoma

Clinical Trials & Observations
Katie Maurer, Isabella N. Grabski, Roch Houot, Satyen H. Gohil, Shogo Miura, Robert Redd, Haoxiang Lyu, Wesley Lu, Yohei Arihara, Justin Budka, Mikaela McDonough, Michela Ansuinelli, Carol Reynolds, Heather Jacene, Shuqiang Li, Kenneth J. Livak, Jerome Ritz, Brodie Miles, Mike Mattie, Donna S. Neuberg, Rafael A. Irizarry, Philippe Armand, Catherine J. Wu, Caron Jacobson
Journal: Blood
Blood (2024) 144 (24): 2490–2502.
https://doi.org/10.1182/blood.2024024381
Published: 2024
Includes: Supplemental data
Journal Articles

Prolonged Persistence and Functional Activity of Anti-BCMA CAR-T Durcabtagene Autoleucel (PHE885) Manufactured Using the T-Charge™ Platform

Shuntaro Ikegawa, Adam S. Sperling, Sarah Nikiforow, Andrew Ghazi, Anthony Christidis, David Quinn, Dexiu Bu, Jennifer Mataraza, David Pearson, Allison Charles, Marc Credi, Nina Orwitz, Madisyn Strange, Rakuyo Tamada, Kevin M. Panaro, Casey Gervais, Michela Ansuinelli, Yohei Arihara, Rao Prabhala, Carol G. Reynolds, Robert Gentleman, Serena De Vita, Nikhil C. Munshi, Jerome Ritz
Journal: Blood
Blood (2024) 144 (Supplement 1): 149.
https://doi.org/10.1182/blood-2024-199890
Published: 2024
Journal Articles

Baseline Immune State and T Cell Clonal Kinetics Are Associated with Response to CAR-T Therapy in Large B-Cell Lymphoma

Katie Maurer, Isabella N. Grabski, Roch Houot, Satyen H Gohil, Shogo Miura, Robert A. Redd, Haoxiang Lyu, Wesley S Lu, Brodie Miles, Mike Mattie, Yohei Arihara, Mikaela M. McDonough, Carol Reynolds, Michela Ansuinelli, Shuqiang Li, Kenneth J. Livak, Jerome Ritz, Scott Rodig, Rafael A. Irizarry, Philippe Armand, Catherine J Wu, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 223.
https://doi.org/10.1182/blood-2023-180819
Published: 2023
Journal Articles

T-Charge™ Manufacturing of the Anti-BCMA CAR-T, Durcabtagene Autoleucel (PHE885), Promotes Expansion and Persistence of CAR-T Cells with High TCR Repertoire Diversity

Shuntaro Ikegawa, Adam S. Sperling, Michela Ansuinelli, Sarah Nikiforow, David Quinn, Dexiu Bu, Jennifer Mataraza, David Pearson, Lawrence Rispoli, Marc A Credi, Nina Orwitz, Yohei Arihara, Rao Prabhala, Lakshmi Bhavani Potluri, Carol Reynolds, Serena De Vita, Nikhil C Munshi, Jerome Ritz
Journal: Blood
Blood (2023) 142 (Supplement 1): 3469.
https://doi.org/10.1182/blood-2023-177721
Published: 2023
Journal Articles

Ipilimumab plus decitabine for patients with MDS or AML in posttransplant or transplant-naïve settings

Clinical Trials & Observations
Jacqueline S. Garcia, Yael Flamand, Livius Penter, Michael Keng, Benjamin K. Tomlinson, Lourdes M. Mendez, Paul Koller, Nicole Cullen, Yohei Arihara, Kathleen Pfaff, Jacquelyn O. Wolff, Andrew M. Brunner, Ilene Galinsky, Asad Bashey, Joseph H. Antin, Corey Cutler, Vincent Ho, Brian A. Jonas, Marlise R. Luskin, Martha Wadleigh, Eric S. Winer, Alexandra Savell, Rebecca Leonard, Taylor Robertson, Matthew S. Davids, Howard Streicher, Scott J. Rodig, Jerome Ritz, Catherine J. Wu, Daniel J. DeAngelo, Donna Neuberg, Richard M. Stone, Robert J. Soiffer
Journal: Blood
Blood (2023) 141 (15): 1884–1888.
https://doi.org/10.1182/blood.2022017686
Published: 2023
Includes: Supplemental data
Journal Articles

Phase I Study of PHE885, a Fully Human BCMA-Directed CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma Manufactured in <2 Days Using the T-Charge TM Platform

Adam S. Sperling, Sarah Nikiforow, Omar Nadeem, Clifton C Mo, Jacob P. Laubach, Kenneth C. Anderson, Alejandro Alonso, Shuntaro Ikegawa, Rao Prabhala, Diego Hernandez Rodriguez, Heather Daley, Kit L. Shaw, Yohei Arihara, Soudeh Ansari, David S Quinn, David Pearson, Anniesha Hack, Louise M Treanor, Dexiu Bu, Jennifer Mataraza, Lawrence Rispoli, Marc Credi, Jerome Ritz, Serena De Vita, Nikhil C. Munshi
Journal: Blood
Blood (2021) 138 (Supplement 1): 3864.
https://doi.org/10.1182/blood-2021-146646
Published: 2021
Journal Articles

Early Reconstitution of CD6+ T Cells after Hematopoietic Cell Transplantation Identifies a Suitable Target for Acute Graft Versus Host Disease Treatment Using Anti-CD6 Monoclonal Antibody Itolizumab

Benedetta Rambaldi, MD, Haesook T. Kim, PhD, Carol Reynolds, PhD, Sharmila Chamling Rai, BSc, Takeru Asano, MD PhD, Yohei Arihara, MD PhD, Mahasweta Gooptu, MD, John Koreth, MBBS, DPhil, Corey Cutler, MD MPH, FRCPC, Sarah Nikiforow, MD PhD, Vincent T. Ho, MD, Joseph H. Antin, MD, Rizwan Romee, MD, Robert J. Soiffer, MD, Jeanette Ampudia, Cherie Tracy Ng, PhD MPH, Stephen Connelly, PhD MBA, Jerome Ritz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-138710
Published: 2020
Journal Articles

Clinical and Immunologic Activity of Ipilimumab Following Decitabine Priming in Post-Allogeneic Transplant and Transplant-Naïve Patients with Relapsed or Refractory Myelodysplastic Syndromes and Acute Myeloid Leukemia: A Multi-Center Phase 1, Two-Arm, Dose-Escalation Study

Jacqueline S Garcia, MD, Lillian Werner, Benjamin K. Tomlinson, MD, Michael Keng, MD, Myrna Nahas, MD, Andrew Brunner, MD, Samer K. Khaled, MD, Alexandra Savell, BS, Marlise Luskin, MDMS, David P. Steensma, MD, Martha Wadleigh, MD, Eric S. Winer, MD, Edwin P. Alyea, III, MD, Corey Cutler, MD MPH, FRCPC, Vincent T. Ho, MD, Donna S Neuberg, ScD, Nicole Cullen, Andreas Kantartzis, Ana Lako, Scott Rodig, MD PhD, R. Coleman Lindsley, MD PhD, Yael Flamand, Claire Manuszak, Ryan Brennick, Mariano Severgnini, Stephanie Andrews, Ilene Galinsky, Pavan Bachireddy, MD, Yohei Arihara, MD PhD, Jerome Ritz, MD, Matthew S. Davids, MD, Howard Streicher, MD, Catherine J. Wu, MD, Richard M. Stone, MD, Daniel J. DeAngelo, MD, Robert J. Soiffer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2015.
https://doi.org/10.1182/blood-2019-126238
Published: 2019
Journal Articles

Anti-CD6 Monoclonal Antibody Itolizumab Efficiently Inhibits T Cell Proliferation after in Vitro TCR Stimulation in the Setting of Acute Graft Versus Host Disease

Benedetta Rambaldi, MD, Carol Reynolds, PhD, Sharmila Chamling Rai, BSc, Takeru Asano, MD PhD, Yohei Arihara, MD PhD, Mahasweta Gooptu, MD, John Koreth, MBBS, DPhil, Corey Cutler, MD MPH, FRCPC, Sarah Nikiforow, MD PhD, Vincent T. Ho, MD, Edwin P. Alyea, III, MD, Joseph H. Antin, MD, Rizwan Romee, MD PhD, Robert J. Soiffer, MD, Domenico Russo, MD, Jeanette Ampudia, BSc, Cherie Tracy Ng, PhD MPH, Stephen Connelly, PhD MBA, Jerome Ritz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4517.
https://doi.org/10.1182/blood-2019-125721
Published: 2019